|
|||||||||||||||
 |
|
||||||||||||||
|
|||||||||||||||
| |||||||||||||||
|
Exercise: Intellectual property rights in bioinformaticsThe purpose of this exercise is to learn how to use the internet to search for existing patents and to be able to answer questions likeHas my protein sequence already been patented? What are the prior arts? How might I broaden my patent claim? First you can read about what a patent is: (read here or here). The danish speaking can also look at Patent og varemærkestyrelsens glimrende hjemmeside or Ãstjysk Innovation's hjemmeside (se , Hvad enhver forsker bør vide om patenter), som er den bedste introduktion jeg har fundet pÃ¥ dansk, pdf oversættelse. What is a patent? What does it allow you to do? exclude other from doing? How long does it last? In which countries? What is a claim? and why are they important? Patent text searchUse the links below to find patents where HIV and vaccine are mentioned in the title. What do these patents cover? European patent office (EPO) search Delphion Intellectual Property Network (formerly IBM Intellectual Property Network - Full access requires subscription) Patent sequence searchNCBI and EMBL maintains databases of patented sequences:Patent sequence databases at embl In this exercise you will use blast to search the NCBI database of patented sequences. Search for the sequence "SYFPEITHI" by going to the blast homepage Select "Standard protein-protein BLAST [blastp]" Paste in the sequence Select the pat (patent) database and press "blast" Press "format" on the results page How many maches did you get? Try also to search using the "search for short nearly exact matches" option on blast homepage. How many maches do you get now? What do the patents corresponding to the top 2 hits cover? (tip: use links above to USPTO or Delphion) You can also use blast to search for homologues to the HLA-A2 sequence in these two databases. >sp|P01892|1A02_HUMAN HLA class I histocompatibility antigen, A-2 alpha chain precursor - Homo sapiens (Human). MAVMAPRTLVLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRF DSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQ RMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQL RAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLT WQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRWEP SSQPTIPIVGIIAGLVLFGAVITGAVVAAVMWRRKSSDRKGGSYSQAASSDSAQGSDVSL TACKVThe top scoring sequences is from sequence US patent 6140305. What does the US patents 6140305 and 5976551 cover? Related LinksCommercial patent sequence databasesDerwent's GENESEQ patent database Articles about interlectual property rights in bioinformaticsFernandez and associates article about IP portfolios in bioinformaticsInterllectual property strategy in bioinformatics Patenting bioinformatic inventions: Emerging trends in the United States (pdf file) Information about US patentsTypes of US Patent Applications/Proceedings Provisional patent application Other linksWorld intellectual property organization Intellectual Property Digital Library The Protein Patent Query System (PPQS). A query system that integrates information from protein sequences databases and SCOP. DNA Patent Database text search. |
| Follow CBS on Twitter |
