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Tuesday, September 05-15

Pairwise Alignment and Database searching


  1. Statistics parameters for local alignments
  2. Protein sequence comparison
  3. Alignment scores

Tuesday, September 19

Maximum likelihood phylogeny


  1. Huelsenbeck
  2. Models of Molecular Evolution and Phylogeny
  3. Statistical methods

Tuesday, September 26

Gene Expression and DNA array technology


  1. Overview (ppt)
  2. Allergy (ppt)

Tuesday, October 10

Protein Modelling, Drug Discovery and Fold recognition


  1. Homology Modeling

Tuesday, October 31

Datadriven Predictions and gene finding with Hidden Markov Models and Neural Networks


  1. Computational prediction of eukaryotic protein-coding genes

Tuesday, November 28

Disease gene finding


  1. Network Biology
  2. From syndrome families to functional genomics