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BioPeople Course in Immunological Bioinformatics - A Hands On Practical Course for Industry

The course will be held on November 30, 9.00 - 17.00, 2011 at The Technical University of Denmark, Bygning 116 Auditorium 81.

BRIEF COURSE DESCRIPTION:

The course will cover the state-of-the-art methods for in-silico T- and B cell epitope discovery. We will touch upon different prediction tools and database searches.

In the course will be used publically available web servers, and no advanced computer skills are needed.

We assume a basic knowledge of the major functions of the immune system although important parts will be briefly explained.

A review regarding different prediction servers and methods will soon be published in Bioinformatics, but is available ahead of publication here.

Programme

8.30 - 9.00: Coffee and breakfast
9.00 - 9.15: Introduction to the immune system Claus Lundegaard; Slides [PDF] .
9.15 - 9.35: Overview of database resources Claus Lundegaard; Slides [PDF] .
9.35 - 10.00: B cell epitope identification and prediction Ole Lund; Slides [PDF] .
10.00 - 10.15: Coffee break
10.15 - 11.20: Prediction of MHC binding Morten Nielsen; Prediction of the MHC-I pathway and integration of prediction systems Morten Nielsen; Slides [PDF] .
11.20 - 12.00: Epitope discovery and rational vaccine design Ole Lund; Slides [PDF] .
12.00 - 13.00: Lunch
13.00 - 16.30: Some notes on performance measures Slides [PDF] .; Hands-on practical session. Development of a T cell-based vaccine against HCV.
16.30 - 17.00: Concluding Remarks and Evaluation