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Calculating performance of a prediction method
Always estimate performance on an independent test
set of sequences, which is non-similar to the training set.
Calculate:
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True Positives (TP)
positive in reality, positive in prediction
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True Negatives (TN) negative
in reality, negative in prediction
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False Positives (FP)
falsely predicted to be positive (negative in reality)
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False Negatives (FN) falsely
missed by prediction (positive in reality)
Various measures of performance:
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Sensitivity tp/(tp + fn)
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Specificity tn/(fp + tn)
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Correlation coefficient
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