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2005 News Archive

CBS paper in ISI Red Hot Biology Top 10 List (December 1, 2005)
It has happened again (for the third time since CBS was started in 1993): A CBS paper is on the ISI Biology Red Hot Paper Top 10 List, now at position eight with 35 citations accumulated over a two month period - more than one every other day. In this period the paper is thus among the ten most cited papers world-wide (in biology). The publication is Jannick Bendtsens paper, Improved prediction of signal peptides: SignalP 3.0 (J.D. Bendtsen, H. Nielsen, G. von Heijne, S. Brunak, J. Mol. Biol. 340:783-795, July, 2004). As of December 1, 2005 it has 200 ISI citations in total.

For more information, contact professor, center director Søren Brunak

More information about ISI Science Watch

Bioinformatics in the Polar seas (November 29, 2005)
Associate professor Nikolaj Blom, CBS, has been selected to participate in the Galathea3 expedition in the summer of 2006, exploring the secrets of the Polar seas. The expedition will sail to the North as well as the South pole, where Nikolaj Blom and his team will collect samples for the project "The DNA of the Polar seas". The project will contribute a new dimension to the Galathea3, not only by going into the depths, but also by focusing on the smallest components. Together with his team, Nikolaj Blom will study the yet unexplored microbiological diversity in the environments of the Polar seas and how these new discoveries at the DNA-level can be applied in practice.

For more information, contact associate professor Nikolaj Blom

More information about the project (in Danish)
More information about Galathea3

ENFIN! Computational systems biology comes to a lab bench near you (October 31, 2005)
CBS partner in a new EU Experimental Network for Functional INtegration which has been awarded DKK 67 million/Euro 9 million over five years. ENFIN is coordinated by Ewan Birney from The European Bioinformatics Institute in Hinxton, UK and brings together some of Europe's best computational and experimental biology labs - 20 groups across 17 institutions in 13 countries - to build a virtual institute that will put Europe at the centre of the systems biology revolution.

ENFIN's products will be applicable to any area of biological research, but a strong experimental focus of the network is understanding the regulation of cell division; this process is deregulated in many diseases, most notably cancer. By applying ENFIN's methods to this important area of biomedical research, ENFIN will contribute directly to the understanding of disease, in addition to making a significant indirect contribution by making the ENFIN infrastructure freely available to researchers across the globe.
For more information, contact professor, center director Søren Brunak

Press Relase in English (EBI)
Press Relase in Danish (CBS, DTU)

immunological bioinformatics New Textbook on:
Immunological Bioinformatics
by Ole Lund, Morten Nielsen, Claus Lundegaard, Can Kesmir and S?ren Brunak

MIT Press
September 2005
ISBN 0-262-12280-4
7 x 9, 312 pp., 93 illus.
24-page color insert
$50.00/?32.95 (CLOTH)

Blurb and Ordering at MIT Press       Link to Amazon

CBS partner in new EU project on Alzheimer's Disease (June 23, 2005)
CBS researchers part of the ADIT research group, who has been awarded 7.5 million Euros by the European Commission to a 5-year project on Alzheimer's Disease. The project is coordinated by the Italien biotech company, Siena Biotech.
The project focuses on the development and the preclinical stage of novel chemical entities endowed with specific neuroprotective activity in Alzheimer's (AD) and capitalizes on the most widely accepted view on the etiology of AD. A validated in vitro model of Ab neurotoxicity, established transcriptomics and proteomics methodologies and sophisticated bioinformatic tools are used in order to identify proteins causally involved in Ab-mediated neurodegeneration. An efficient drug discovery pipeline, including stringent target validation based on in vitro, in vivo and ex vivo approaches, will be employed to bring two drug candidates to the clinic.

For more information, contact professor, center director Søren Brunak

The Astronaut Finals - Chances of the first bioinformatician in space are now 1:9 (June 9, 2005)
In December 2004, three CBS researchers were among the 266 applicants aspirering to be one of the first Danish astronauts. Graduate engineer, PhD Hanne Jarmer was at the time one out of only 37 female candidates. Now, Hanne Jarmer is the only woman among the nine candidates left.
On June 9 the remaining candidates were presented at a press conference organized by the Danish Ministry for Science, Technology and Innovation, and the Danish Space Center.

DR news article, June 9, 2005 (in Danish)
Read more about the June 9 press conference (in Danish)

New PhD course in Systems Biology (June 6, 2005)
In collaboration with Center for Microbial Biotechnology, CBS now offers an intensive, three-day PhD course in Systems Biology. The course is held from June 3 - 6, 2005 at the Technical University of Denmark. Approximately 40 students from all over Europe participate in this year's course.

More information and course programme

New e-learning concept lauched at CBS (April 5, 2005)
Yesterday, 25 PhD students from all over the world were able to follow a notorically overbooked PhD course within bioinformatics online.

As a consequence of the massive interest in the PhD course in Biological Sequence Analysis that has been running since 1996, CBS now offers an internet transmitted version of the course.

The internet version of the course is a combination of live, real-time transmitted lectures and webbased exercises, where the students will be introduced to a range of computational methods used in the field and to internet biocomputing services available. It is possible to communicate and ask questions during the lectures and exercises via chat lines maintained by CBS staff.

The transmission of the course is made possible through the software Breeze Live and the Technical University of Denmark is the first Danish university to use this system. The project is supported by DTU and FOBI (Research School for Biotechnology).

Course page
Read more (in Danish)

CBS researcher co-author on article in Nature (March 2005)
CBS post doc Thomas Sicheritz-Pontén part of the research team who has sequenced and analyzed the whole genome of Entamoeba histolytica - an intestinal parasite that is the causative agent of amoebiasis, which is a significant source of morbidity and mortality in developing countries.
Analysis of the genome provides new insights into the workings and genome evolution of a major human pathogen.

Abstract of article

Biology in four dimensions - the factor of time gives scientists insight into cellular machines(February 3, 2005)
CBS and EMBL researchers publish an article in this week's edition of Science on the time element in the cell cycle.
Most things that happen in the cell are the work of molecular machines?-? complexes of proteins that carry out important cellular functions. Until now, scientists didn't have a clear idea of when proteins form these machines ?- are these complexes pre-fabricated or put together on the spot for each specific job? By drawing together many types of data in a fascinating new model, this question has now been answered.

Abstract of article
Read more in joint CBS/EMBL press release
Danish version of press release
Read more about the CBS Integrative Systems Biology research group

CBS partner in the EU Network of Excellence EMBRACE (January 31, 2005)
CBS researchers are part of a pan-European bioinformatics task force who has been awarded 8.3 million Euros by the European Commission. The EMBRACE network will improve access to biological information for scientists throughtout and beyond Europe by essentially creating a 'data-grid' - the EMBRACEgrid - which will allow researchers to make the most of dispersed data resources.
By enabling data providers to provide well-defined interfaces to their databases that will conform to the same standards, EMBRACE will turn the relationship between user and provideron its head.

The network encompasses computational biologists from 17 institutes in 11 countries and is coordinated by associate director Graham Cameron from the European Bioinformatics Institute (EBI) in Hinxton, UK.

Read more