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2013
Parallel evolution of tumor subclones mimics diversity between tumors.
Martinez P, Birkbak NJ, Gerlinger M, McGranahan N, Burrell R, Rowan A, Joshi T, Fisher R, Larkin J, Szallasi Z, Swanton C
J Pathol. 2013 May 28, 2013 |
PubMed
Relevant URL
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Deconvoluting complex tissues for expression quantitative trait locus-based analyses.
Seo JH, Li Q, Fatima A, Eklund A, Szallasi Z, Polyak K, Richardson AL, Freedman ML
Philos Trans R Soc Lond B Biol Sci., 2013 |
PubMed
Relevant URL
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Prognostic and Predictive Markers in Metastatic Renal Cell Carcinoma
Khattak MA, Bakr F, Krzystanek M, Szallasi Z, Gerlinger M, Santos C, Swanton C, Pickering LM, Gore ME, Larkin JM
Journal of Clinical Oncology, Vol. 31, No. 7, 2013, p. 20971-972., 2013 |
PubMed
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Biasogram: Visualization of Confounding Technical Bias in Gene Expression Data
Krzystanek M, Szallasi Z, Eklund AC
PLOS ONE, April 16 2013, 2013 |
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2012
Telomeric allelic imbalance indicates defective DNA repair and sensitivity to DNA-damaging agents
Birkbak NJ, Wang ZC, Kim JY, Eklund AC, Li Q, Tian R, Bowman-Colin C, Li Y, Greene-Colozzi A, Iglehart JD, Tung N, Ryan PD, Garber JE, Silver DP, Szallasi Z, Richardson AL
Cancer Discov. 2012 Apr;2(4):366-75. Epub 2012 Mar 22., 2012 |
PubMed
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Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
Gerlinger M, Rowan AJ, Horswell S, Larkin J, Endesfelder D, Gronroos E, Martinez P, Matthews N, Stewart A, Tarpey P, Varela I, Phillimore B, Begum S, McDonald NQ, Butler A, Jones D, Raine K, Latimer C, Santos CR, Nohadani M, Eklund AC, Spencer-Dene B, Clark G, Pickering L, Stamp G, Gore M, Szallasi Z, Downward J, Futreal PA, Swanton C
N Engl J Med., 2012 |
Relevant URL
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2011
Chromosomal instability confers intrinsic multidrug resistance
Lee AJ, Endesfelder D, Rowan AJ, Walther A, Birkbak NJ, Futreal PA, Downward J, Szallasi Z, Tomlinson IP, Howell M, Kschischo M, Swanton C
Cancer Res. 2011 Mar 1;71(5):1858-70., 2011 |
PubMed
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A breast cancer meta-analysis of two expression measures of chromosomal instability reveals a relationship with younger age at diagnosis and high risk histopathological variables
Endesfelder D, McGranahan N, Birkbak NJ, Szallasi Z, Kschischo M, Graham TA, Swanton C
Oncotarget. 2011 Jul;2(7):529-37., 2011 |
PubMed
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CERT depletion predicts chemotherapy benefit and mediates cytotoxic and polyploid-specific cancer cell death through autophagy induction
Lee AJ, Roylance R, Sander J, Gorman P, Endesfelder D, Kschischo M, Jones NP, East P, Nicke B, Spassieva S, Obeid LM, Birkbak NJ, Szallasi Z, McKnight NC, Rowan AJ, Speirs V, Hanby AM, Downward J, Tooze SA, Swanton C
J Pathol. 2012 Feb;226(3):482-94. doi: 10.1002/path.2998. Epub 2011 Oct 19., 2011 |
PubMed
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Jetset: selecting the optimal microarray probe set to represent a gene
Li Q, Birkbak NJ, Gyorffy B, Szallasi Z, Eklund AC
BMC Bioinformatics, 2011 |
PubMed
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Relationship of Extreme Chromosomal Instability with Long-term Survival in a Retrospective Analysis of Primary Breast Cancer
Roylance R, Endesfelder D, Gorman P, Burrell RA, Sander J, Tomlinson I, Hanby AM, Speirs V, Richardson AL, Birkbak NJ, Eklund AC, Downward J, Szallasi Z, Kschischo M, Swanton C
Cancer Epidemiol Biomarkers Prev., August 2, 2011 |
PubMed
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Consistent metagenes from cancer expression profiles yield agent specific predictors of chemotherapy response
Li Q, Eklund AC, Birkbak NJ, Desmedt C, Haibe-Kains B, Sotiriou C, Symmans WF, Pusztai L, Brunak S, Richardson AL, Szallasi Z
BMC Bioinformatics, July 28, 2011 |
PubMed
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Paradoxical relationship between chromosomal instability and survival outcome in cancer
Birkbak NJ, Eklund AC, Li Q, McClelland SE, Endesfelder D, Tan P, Tan IB, Richardson AL, Szallasi Z, Swanton C
Cancer Research, January 26, 2011 |
PubMed
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2010
Minimising Immunohistochemical False Negative ER Classification Using a Complementary 23 Gene Expression Signature of ER Status
Li Q, Eklund AC, Juul N, Haibe-Kains B, Workman CT, Richardson AL, Szallasi Z, Swanton C
PLoS One, December 1, 2010 |
PubMed
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Predictive biomarker discovery through the parallel integration of clinical trial and functional genomics datasets
Swanton C, Larkin JM, Gerlinger M, Eklund AC, Howell M, Stamp G, Downward J, Gore M, Futreal PA, Escudier B, Andre F, Albiges L, Beuselinck B, Oudard S, Hoffmann J, Gyorffy B, Torrance C, Boehme KA, Volkmer H, Toschi L, Nicke B, Beck M, Szallasi Z
Genome Med., 2010 |
PubMed
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Targeting chromosomal instability and tumour heterogeneity in HER2 positive breast cancer
Burrell RA, Juul N, Johnston SR, Reis-Filho J, Szallasi Z, Swanton C
Journal of Cell Biochemistry, 2010 |
PubMed
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Assessment of an RNA interference screen-derived mitotic and ceramide pathway metagene as a predictor of response to neoadjuvant paclitaxel for primary triple-negative breast cancer: a retrospective analysis of five clinical trials
Juul N, Szallasi Z, Eklund AC, Li Q, Burrell RA, Gerlinger M, Valero V, Andreopoulou E, Esteva FJ, Symmans WF, Desmedt C, Haibe-Kains B, Sotiriou C, Pusztai L, Swanton C
Lancet Oncol., 2010 |
PubMed
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Amplification of LAPTM4B and YWHAZ contributes to chemotherapy resistance and recurrence of breast cancer
Li Y, Zou L, Li Q, Haibe-Kains B, Tian R, Li Y, Desmedt C, Sotiriou C, Szallasi Z, Iglehart JD, Richardson AL, Wang ZC
Nat Med, 2010 |
PubMed
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Efficacy of Neoadjuvant Cisplatin in Triple-Negative Breast Cancer
Silver DP, Richardson AL, Eklund AC, Wang ZC, Szallasi Z, Li Q, Juul N, Leong CO, Calogrias D, Buraimoh A, Fatima A, Gelman RS, Ryan PD, Tung NM, De Nicolo A, Ganesan S, Miron A, Colin C, Sgroi DC, Ellisen LW, Winer EP, Garber JE
J Clin Oncol, 2010 |
PubMed
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2009
An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients
Györffy B, Lanczky A, Eklund AC, Denkert C, Budczies J, Li Q, Szallasi Z
Breast Cancer Res Treat, 2009 |
PubMed
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Optimization of the BLASTN substitution matrix for prediction of non-specific DNA microarray hybridization
Aron C Eklund; Pia Friis; Rasmus Wernersson; Zoltan Szallasi
Nucleic Acids Research doi: 10.1093/nar/gkp1116, 2009 |
PubMed
Read article
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Evaluation of microarray preprocessing algorithms based on concordance with rt-PCR in clinical samples
Gyorffy B, Molnar B, Lage H, Szallasi Z, Eklund AC
PLoS ONE;4(5):e5645, 2009 |
PubMed
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Chromosomal instability determines taxane response
Swanton C, Nicke B, Schuett M, Eklund AC, Ng C, Li Q, Hardcastle T, Lee A, Roy R, East P, Kschischo M, Endesfelder D, Wylie P, Kim SN, Chen JG, Howell M, Ried T, Habermann JK, Auer G, Brenton JD, Szallasi Z, Downward J
Proc Natl Acad Sci U S A;106(21):8671-6, 2009 |
PubMed
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2008
Concordance of exon array and real-time PCR assessment of gene expression following cancer cell cytotoxic drug exposure
Lee AJ, East P, Pepper S, Nicke B, Szallasi Z, Eklund AC, Downward J, Swanton C
Cell Cycle. 15;7(24):3947-8. Epub 2008 Dec 17, 2008 |
PubMed
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Functional genomic analysis of drug sensitivity pathways to guide adjuvant strategies in breast cancer
Swanton C, Szallasi Z, Brenton JD, Downward J
Breas Cancer Research, 2008;10(5):214. Epub 2008 Oct 31, 2008 |
PubMed
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A large-scale analysis of tissue-specific pathology and gene expression of human disease genes and complexes
Lage K, Hansen NT, Karlberg EO, Eklund AC, Roque F, Donahoe PK, Szallasi Z, Jensen TS, Brunak S
Proceedings of the National Academy of Sciences of the United States of America, 2008 Dec 30;105(52):20870-5. Epub 2008 Dec 22, 2008 |
PubMed
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Correction of technical bias in clinical microarray data improves concordance with known biological information
Eklund AC, Szallasi Z
Genome Biol., 4;9(2):R26, 2008 |
PubMed
Web
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2006
A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers
Carter SL, Eklund AC, Kohane IS, Harris LN, Szallasi Z
Nat Genet 38(9):1043-8, 2006 |
PubMed
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This file was last modified Friday 31st 2013f May 2013 08:37:15 GMT |
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