Prediction of novel archaeal enzymes from sequence-derived features.
Jensen LJ, Skovgaard M, Brunak S.
Protein Science: 11: 2894-2898, 2002.
Center for Biological Sequence Analysis, BioCentrum-DTU,
The Technical University of Denmark, DK-2800 Lyngby, Denmark
The completely sequenced archaeal genomes potentially encode, among their
many functionally uncharacterized genes, novel enzymes of biotechnological
interest. We have developed a prediction method for detection and
classification of enzymes from sequence alone (available at
). The method does not make use
of sequence similarity; rather, it relies on predicted protein features like
cotranslational and posttranslational modifications, secondary structure, and
simple physical/chemical properties.
Lars Juhl Jensen,