Work on a large number of biological problems benefits tremendously from having an easy way
to access the annotation of DNA sequence features, such as intron/exon structure, the contents
of promoter regions and the location of other genes in upsteam and downstream regions. For
example, taking the placement of introns within a gene into account can help in a phylogenetic
analysis of homologous genes. Designing experiments for investigating UTR regions using PCR or
DNA microarrays require knowledge of known elements in UTR regions and the positions and
strandness of other genes nearby on the chromosome. A wealth of such information is already
known and documented in databases such as GenBank and the NCBI Human Genome builds. However,
it usually requires significant bioinformatics skills and intimate knowledge of the data format
to access this information.
Presented here is a highly flexible and easy-to-use tool for
extracting feature annotation from GenBank entries. The tool is also useful for extracting
datasets corresponding to a particular feature (e.g. promoters). Most importantly, the output
data format is highly consistent, easy to handle for the user and easy to parse computationally.
FeatureExtract - extraction of sequence annotation made easy.
Nucleic Acids Research, 2005, Vol. 33, Web Server issue W567-W569
Rasmus Wernersson: email@example.com