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Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
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Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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Data for AE000516  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AE000516.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
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Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AE000516_1094 CDS_1157999-1156470 86.2 4.4e-24 1
AE000516_4014 CDS_4203415-4201895 83.7 2.2e-23 1
AE000516_3463 CDS_3621513-3619810 74.9 7.2e-21 1
AE000516_0803 CDS_854537-855994 73.5 1.8e-20 1
AE000516_0510 CDS_580739-581971 72.4 3.7e-20 1
AE000516_1089 CDS_1151763-1149148 65.2 4.1e-18 1
AE000516_1038 CDS_1097547-1099061 60.6 8e-17 1
AE000516_0952 CDS_1005922-1004513 54.0 5.9e-15 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AE000516_1094 1/1 277 344 .. 1 87 [] 86.2 4.4e-24
AE000516_4014 1/1 277 343 .. 1 87 [] 83.7 2.2e-23
AE000516_3463 1/1 295 362 .. 1 87 [] 74.9 7.2e-21
AE000516_0803 1/1 249 313 .. 1 87 [] 73.5 1.8e-20
AE000516_0510 1/1 157 223 .. 1 87 [] 72.4 3.7e-20
AE000516_1089 1/1 643 711 .. 1 87 [] 65.2 4.1e-18
AE000516_1038 1/1 239 311 .. 1 87 [] 60.6 8e-17
AE000516_0952 1/1 253 319 .. 1 87 [] 54.0 5.9e-15

Alignments of top-scoring domains:
AE000516_1094: domain 1 of 1, from 277 to 344: score 86.2, E = 4.4e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sHELRTPL+aI+gyael + ++ ++l++ +
AE000516_1 277 RMRQFITDASHELRTPLAAIQGYAELTRQDS-------SDLPPTT-- 314

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l +i++ea+r+ L+++lL lsr+ +g
AE000516_1 315 ----------EYALARIESEARRMTLLVDELLLLSRLSEG 344

AE000516_4014: domain 1 of 1, from 277 to 343: score 83.7, E = 2.2e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a++sHELRTPL+aIrgy+el ++ ++e +
AE000516_4 277 RVRQFVADASHELRTPLAAIRGYTELTQR---------IGDDPEAV- 313

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + +++ +e+er+ rL++dlL l+r+++g
AE000516_4 314 ----------AHAMSRVASETERITRLVEDLLLLARLDSG 343

AE000516_3463: domain 1 of 1, from 295 to 362: score 74.9, E = 7.2e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f++++sHELRTPLt++r++a+l+ + ++++l++
AE000516_3 295 LQRRFTSDVSHELRTPLTTVRMAADLIYD-------HSADLDPTL-- 332

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ +e + +e++r + L+ndlL++sr +ag
AE000516_3 333 ----------RRSTELMVSELDRFETLLNDLLEISRHDAG 362

AE000516_0803: domain 1 of 1, from 249 to 313: score 73.5, E = 1.8e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sHELRTPLt+Irg+ael + ++ + ++
AE000516_0 249 RMRQFITDASHELRTPLTTIRGFAELYRQGA-----------ARDV- 283

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+l++i++ea r+ L++dlL l+r++a
AE000516_0 284 ----------GMLLSRIESEASRMGLLVDDLLLLARLDAH 313

AE000516_0510: domain 1 of 1, from 157 to 223: score 72.4, E = 3.7e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+an+sHEL+TP+ a+ ++ae+Ll+ ++ ++e++
AE000516_0 157 ARRDFVANVSHELKTPVGAMALLAEALLA---------SADDSETV- 193

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++ e++l ea+rl +++ +l +lsr++
AE000516_0 194 ----------RRFAEKVLIEANRLGDMVAELIELSRLQGA 223

AE000516_1089: domain 1 of 1, from 643 to 711: score 65.2, E = 4.1e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +l+++sH+LRTPL+a + +++ L++ +d + s+e++
AE000516_1 643 LRRSLLSAVSHDLRTPLAAAKVAVSSLRT-------EDVAFSPEDT- 681

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+l ti++++++l +L+ +lLd sr+ ag
AE000516_1 682 ----------AELLATIEESIDQLTALVANLLDSSRLAAG 711

AE000516_1038: domain 1 of 1, from 239 to 311: score 60.6, E = 8e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +++ ++ HELRTPLt++r+++elL + + ++g + l+ +++
AE000516_1 239 RQARLVTDAGHELRTPLTSLRTNVELLMASM---APGAPRLPKQEM- 281

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ +l ++e l+ L+ dl dlsr +ag
AE000516_1 282 ----------VDLRADVLAQIEELSTLVGDLVDLSRGDAG 311

AE000516_0952: domain 1 of 1, from 253 to 319: score 54.0, E = 5.9e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a sHELRTPLta+r+++e+L + +l+++qr
AE000516_0 253 SARDFAAVSSHELRTPLTAMRTNLEVLST---------LDLPDDQR- 289

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e l+ ++r r+++ ++ l l++ e
AE000516_0 290 ----------KEVLNDVIRTQSRIEATLSALERLAQGELS 319


Histogram of all scores:
score obs exp (one = represents 14 sequences)
----- --- ---
-15 5 0|=
-14 24 0|==
-13 90 3|*======
-12 227 95|======*==========
-11 433 496|=============================== *
-10 744 921|====================================================== *
-9 823 951|==========================================================*
-8 677 712|================================================= *
-7 479 448|===============================*===
-6 282 258|==================*==
-5 176 141|==========*==
-4 104 75|=====*==
-3 61 40|==*==
-2 29 21|=*=
-1 9 10|*
0 8 5|*
1 2 2|*
2 3 1|*
3 2 0|=
4 1 0|=
5 0 0|
> 6 10 -|=


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 279.3917
P(chi-square) = 0

Total sequences searched: 4189

Whole sequence top hits:
tophits_s report:
Total hits: 8
Satisfying E cutoff: 8
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 8
Satisfying E cutoff: 8
Total memory: 24K


Acknowledgements:

This research is funded by:

Developed by: