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Thermotogae
Classification of phyla is from NCBI page
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2 accessions found for Vibrio cholerae O1 biovar El Tor str. N16961  

Data for AE003853  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AE003853.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AE003853_0694 CDS_655882-652820 94.5 5.1e-27 1
AE003853_0721 CDS_683045-680472 91.9 2.8e-26 1
AE003853_0520 CDS_468993-470486 55.8 4.8e-16 1
AE003853_0235 CDS_258742-260391 52.9 3.2e-15 1
AE003853_0690 CDS_648174-645805 44.3 8.7e-13 2
AE003853_0254 CDS_278438-276984 28.2 3.1e-08 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AE003853_0694 1/1 505 570 .. 1 87 [] 94.5 5.1e-27
AE003853_0721 1/1 479 544 .. 1 87 [] 91.9 2.8e-26
AE003853_0520 1/1 269 337 .. 1 87 [] 55.8 4.8e-16
AE003853_0235 1/1 312 379 .. 1 87 [] 52.9 3.2e-15
AE003853_0690 2/2 563 631 .. 1 87 [] 41.9 4.2e-12
AE003853_0254 1/1 279 333 .. 1 74 [. 28.2 3.1e-08

Alignments of top-scoring domains:
AE003853_0694: domain 1 of 1, from 505 to 570: score 94.5, E = 5.1e-27
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTP+++++g+a lL++ t+l++ q
AE003853_0 505 AKSAFLATMSHEIRTPMNGVLGTARLLQD---------TTLTSTQ-- 540

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ y+++i r++++ll+++nd+Ld+s+ieag
AE003853_0 541 ----------QHYVQVINRSGRSLLAILNDVLDYSKIEAG 570

AE003853_0721: domain 1 of 1, from 479 to 544: score 91.9, E = 2.8e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ efla +sHELRTPL++++g ++lL++ t+l++eq
AE003853_0 479 VRAEFLAKMSHELRTPLNGVLGVSQLLKR---------TPLNDEQ-- 514

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re + ++ +++e+ll+ +nd+Ld+sr+e+g
AE003853_0 515 ----------REHVAVLCSSGEHLLAVLNDILDFSRLEQG 544

AE003853_0520: domain 1 of 1, from 269 to 337: score 55.8, E = 4.8e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la++sH+L+TPL aI+g a +L + + +ls e++
AE003853_0 269 TRTTLLASVSHDLKTPLGAIIGSATTLTD-------PSLHLSTETQ- 307

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+l +i +++erl+r + lLd++r a
AE003853_0 308 ----------QELLTSIAEQGERLNRSLTKLLDITRYTAS 337

AE003853_0235: domain 1 of 1, from 312 to 379: score 52.9, E = 3.2e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ef+an+sHELR P taI+g a++ l+ + ++++
AE003853_0 312 QQKEFFANVSHELRSPATAILGEAQITLR---------SRHNSDD-- 347

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
eyr+ l +i ++ae+l i+dlL l r ++
AE003853_0 348 --------EYRQTLLRISESAEQLAFRIEDLLMLIRHDER 379

AE003853_0690: domain 2 of 2, from 563 to 631: score 41.9, E = 4.2e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l+HEL++PL+a+++y+ ++ l +e++ q+
AE003853_0 563 VVGQTMTSLAHELNQPLSAMSAYLFSARLAL-------EEAPQAQL- 601

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ l+ i++ +er+ +++n l+ ++r +
AE003853_0 602 ----------ATSLDHIENLTERMGKIVNSLRHFARKNSS 631

AE003853_0254: domain 1 of 1, from 279 to 333: score 28.2, E = 3.1e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ l l HELRTP+t++ +++e L+ ++ +els++
AE003853_0 279 ERRFILQLLTHELRTPITSLGFTVESLRSQF-------DELSPKA-- 316

peLRledpeyreyletilreaerllrL<-*
+e l ++ + +rl +L
AE003853_0 317 ----------QESLWRLMADHQRLAQL 333


Histogram of all scores:
score obs exp (one = represents 4 sequences)
----- --- ---
-15 2 0|=
-14 22 0|======
-13 29 0|========
-12 74 24|=====*=============
-11 130 129|================================*
-10 179 240|============================================= *
-9 190 247|================================================ *
-8 138 185|=================================== *
-7 125 117|=============================*==
-6 68 67|================*
-5 57 36|========*======
-4 22 19|====*=
-3 16 10|==*=
-2 14 5|=*==
-1 9 2|*==
> 0 17 -|=====


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 165.6315
P(chi-square) = 2.224e-30

Total sequences searched: 1092

Whole sequence top hits:
tophits_s report:
Total hits: 6
Satisfying E cutoff: 6
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 6
Satisfying E cutoff: 6
Total memory: 23K


Acknowledgements:

This research is funded by:

Developed by: