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Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
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Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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Data for AE004091  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AE004091.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AE004091_0930 CDS_1015752-1012975 105.1 2.7e-29 1
AE004091_1613 CDS_1755562-1753607 93.7 4.6e-26 1
AE004091_4854 CDS_5452150-5454978 93.0 7.2e-26 1
AE004091_4112 CDS_4600102-4595849 92.6 9.4e-26 1
AE004091_3463 CDS_3870795-3873554 91.3 2.2e-25 1
AE004091_2825 CDS_3177090-3179450 89.7 6.1e-25 1
AE004091_5359 CDS_6027542-6028873 85.2 1.2e-23 1
AE004091_4980 CDS_5598275-5595279 76.9 2.5e-21 1
AE004091_3946 CDS_4426850-4423212 76.6 3.1e-21 1
AE004091_1440 CDS_1567848-1569293 76.5 3.3e-21 1
AE004091_3045 CDS_3408546-3406321 74.7 1.1e-20 1
AE004091_1638 CDS_1780536-1783193 73.3 2.7e-20 1
AE004091_4546 CDS_5093378-5094970 72.9 3.4e-20 1
AE004091_2811 CDS_3163382-3164713 72.5 4.5e-20 1
AE004091_5482 CDS_6174694-6176481 69.3 3.8e-19 1
AE004091_0465 CDS_523943-525367 68.0 8.4e-19 1
AE004091_1160 CDS_1256094-1257452 65.4 4.7e-18 1
AE004091_0758 CDS_825073-826455 65.4 4.8e-18 1
AE004091_5122 CDS_5772298-5773374 64.9 6.6e-18 1
AE004091_3974 CDS_4455676-4453289 64.5 8.3e-18 1
AE004091_4380 CDS_4912151-4910871 64.2 1.1e-17 1
AE004091_4884 CDS_5481070-5482461 63.5 1.6e-17 1
AE004091_2584 CDS_2922569-2919591 62.6 2.8e-17 1
AE004091_1100 CDS_1189172-1190380 62.6 3e-17 1
AE004091_1398 CDS_1518768-1517146 60.7 1e-16 1
AE004091_4117 CDS_4604621-4606807 60.0 1.6e-16 1
AE004091_3207 CDS_3595942-3597279 56.2 2e-15 1
AE004091_3272 CDS_3660022-3663501 55.4 3.3e-15 1
AE004091_1978 CDS_2160363-2163008 54.8 4.6e-15 1
AE004091_3079 CDS_3451506-3452801 52.4 2.3e-14 1
AE004091_0932 CDS_1016657-1017994 52.3 2.4e-14 1
AE004091_4775 CDS_5364760-5366193 51.4 4.2e-14 1
AE004091_1800 CDS_1951725-1950439 51.4 4.2e-14 1
AE004091_5197 CDS_5852558-5851239 50.3 8.8e-14 1
AE004091_4723 CDS_5304011-5306962 49.2 1.9e-13 1
AE004091_2688 CDS_3038803-3040143 48.4 3.1e-13 1
AE004091_2481 CDS_2798412-2799734 48.3 3.3e-13 1
AE004091_2179 CDS_2397569-2399668 46.5 1.1e-12 1
AE004091_2525 CDS_2844489-2845907 45.5 2e-12 1
AE004091_1245 CDS_1347824-1345248 44.4 4.3e-12 1
AE004091_5510 CDS_6206210-6204444 44.0 5.5e-12 1
AE004091_1994 CDS_2178121-2179815 43.5 7.4e-12 1
AE004091_5163 CDS_5813727-5815565 38.2 2.5e-10 1
AE004091_4293 CDS_4819348-4816580 36.3 8e-10 1
AE004091_3192 CDS_3583592-3582171 35.2 1.7e-09 1
AE004091_1338 CDS_1450449-1448548 32.6 9.1e-09 1
AE004091_4398 CDS_4927998-4930094 32.4 1e-08 2
AE004091_4494 CDS_5030248-5028980 31.7 1.6e-08 1
AE004091_4197 CDS_4696035-4693759 29.5 7e-08 1
AE004091_1182 CDS_1278362-1279708 27.2 3.1e-07 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AE004091_0930 1/1 283 348 .. 1 87 [] 105.1 2.7e-29
AE004091_1613 1/1 265 330 .. 1 87 [] 93.7 4.6e-26
AE004091_4854 1/1 414 479 .. 1 87 [] 93.0 7.2e-26
AE004091_4112 1/1 764 829 .. 1 87 [] 92.6 9.4e-26
AE004091_3463 1/1 407 472 .. 1 87 [] 91.3 2.2e-25
AE004091_2825 1/1 305 370 .. 1 87 [] 89.7 6.1e-25
AE004091_5359 1/1 209 276 .. 1 87 [] 85.2 1.2e-23
AE004091_4980 1/1 506 571 .. 1 87 [] 76.9 2.5e-21
AE004091_3946 1/1 709 775 .. 1 87 [] 76.6 3.1e-21
AE004091_1440 1/1 243 309 .. 1 87 [] 76.5 3.3e-21
AE004091_3045 1/1 247 313 .. 1 87 [] 74.7 1.1e-20
AE004091_1638 1/1 650 718 .. 1 87 [] 73.3 2.7e-20
AE004091_4546 1/1 309 375 .. 1 87 [] 72.9 3.4e-20
AE004091_2811 1/1 225 291 .. 1 87 [] 72.5 4.5e-20
AE004091_5482 1/1 375 443 .. 1 87 [] 69.3 3.8e-19
AE004091_0465 1/1 255 320 .. 1 87 [] 68.0 8.4e-19
AE004091_1160 1/1 222 287 .. 1 87 [] 65.4 4.7e-18
AE004091_0758 1/1 244 309 .. 1 87 [] 65.4 4.8e-18
AE004091_5122 1/1 131 196 .. 1 87 [] 64.9 6.6e-18
AE004091_3974 1/1 418 483 .. 1 87 [] 64.5 8.3e-18
AE004091_4380 1/1 211 277 .. 1 87 [] 64.2 1.1e-17
AE004091_4884 1/1 243 309 .. 1 87 [] 63.5 1.6e-17
AE004091_2584 1/1 607 673 .. 1 87 [] 62.6 2.8e-17
AE004091_1100 1/1 181 247 .. 1 87 [] 62.6 3e-17
AE004091_1398 1/1 179 244 .. 1 87 [] 60.7 1e-16
AE004091_4117 1/1 503 566 .. 1 87 [] 60.0 1.6e-16
AE004091_3207 1/1 227 291 .. 1 87 [] 56.2 2e-15
AE004091_3272 1/1 798 864 .. 1 87 [] 55.4 3.3e-15
AE004091_1978 1/1 513 579 .. 1 87 [] 54.8 4.6e-15
AE004091_3079 1/1 235 299 .. 1 87 [] 52.4 2.3e-14
AE004091_0932 1/1 233 292 .. 1 87 [] 52.3 2.4e-14
AE004091_4775 1/1 239 304 .. 1 87 [] 51.4 4.2e-14
AE004091_1800 1/1 208 273 .. 1 87 [] 51.4 4.2e-14
AE004091_5197 1/1 222 282 .. 1 87 [] 50.3 8.8e-14
AE004091_4723 1/1 756 822 .. 1 87 [] 49.2 1.9e-13
AE004091_2688 1/1 234 293 .. 1 87 [] 48.4 3.1e-13
AE004091_2481 1/1 225 289 .. 1 87 [] 48.3 3.3e-13
AE004091_2179 1/1 330 396 .. 1 87 [] 46.5 1.1e-12
AE004091_2525 1/1 249 315 .. 1 87 [] 45.5 2e-12
AE004091_1245 1/1 496 561 .. 1 87 [] 44.4 4.3e-12
AE004091_5510 1/1 362 430 .. 1 87 [] 44.0 5.5e-12
AE004091_1994 1/1 202 267 .. 1 87 [] 43.5 7.4e-12
AE004091_5163 1/1 378 446 .. 1 87 [] 38.2 2.5e-10
AE004091_4293 1/1 690 760 .. 1 87 [] 36.3 8e-10
AE004091_3192 1/1 270 313 .. 1 65 [. 35.2 1.7e-09
AE004091_1338 1/1 407 475 .. 1 87 [] 32.6 9.1e-09
AE004091_4494 1/1 207 273 .. 1 87 [] 31.7 1.6e-08
AE004091_4197 1/1 526 599 .. 1 87 [] 29.5 7e-08
AE004091_1182 1/1 238 300 .. 1 87 [] 27.2 3.1e-07

Alignments of top-scoring domains:
AE004091_0930: domain 1 of 1, from 283 to 348: score 105.1, E = 2.7e-29
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHE+RTPL++I+g++ lL++ +els+ q
AE004091_0 283 IKSEFLANMSHEIRTPLNGILGFTNLLQK---------SELSPRQ-- 318

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl ti+++ae+ll +in++Ld+s+ieag
AE004091_0 319 ----------QDYLTTIQKSAESLLGIINEILDFSKIEAG 348

AE004091_1613: domain 1 of 1, from 265 to 330: score 93.7, E = 4.6e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fla++sHELRTP+++++g+++lL++ te++ eq
AE004091_1 265 AKSDFLAMMSHELRTPMNGVLGMLQLLET---------TEQTREQ-- 300

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ey+ + +++e+ll+ ind+Ld+srie g
AE004091_1 301 ----------AEYTALATESTEHLLKVINDILDFSRIERG 330

AE004091_4854: domain 1 of 1, from 414 to 479: score 93.0, E = 7.2e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k efla +sHE+RTP+++++g++elLl t+ls++q
AE004091_4 414 TKAEFLAKISHEIRTPMNGVLGMTELLLG---------TPLSAKQ-- 449

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+y++ti+++++ ll Lin++Ld+s++e+g
AE004091_4 450 ----------RDYVQTIHSAGNELLTLINEILDISKLESG 479

AE004091_4112: domain 1 of 1, from 764 to 829: score 92.6, E = 9.4e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks flan+sHE+RTP++a++g+++l++ t+l+e q
AE004091_4 764 AKSSFLANMSHEIRTPMNAVLGMLQLARQ---------TDLNERQ-- 799

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+yl+++ ++a +ll L+nd+Ld+s+ieag
AE004091_4 800 ----------RDYLDKASSAATSLLGLLNDILDYSKIEAG 829

AE004091_3463: domain 1 of 1, from 407 to 472: score 91.3, E = 2.2e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fla +sHE+RTPL++++g+++lL++ t+l+ q
AE004091_3 407 AKSRFLAKMSHEIRTPLNGVLGMLQLLRD---------TPLDRGQ-- 442

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ y+eti +++ l + ind+Ld++rie+g
AE004091_3 443 ----------AAYVETIASSGSALMSVINDILDYARIESG 472

AE004091_2825: domain 1 of 1, from 305 to 370: score 89.7, E = 6.1e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+ flan+sHE+RTPL++++g+++l l+ ++l++eq
AE004091_2 305 ARASFLANMSHEIRTPLNGLLGMLSLSLD---------GPLTPEQ-- 340

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l++++++++ l +L+nd+Ldls+ eag
AE004091_2 341 ----------RQQLSIAHDSGKVLVELLNDVLDLSKFEAG 370

AE004091_5359: domain 1 of 1, from 209 to 276: score 85.2, E = 1.2e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +f+an+sHELRTPLt+I gy+e+Ll+++ ++ ++
AE004091_5 209 MRKDFVANVSHELRTPLTVIAGYLETLLDNV-------EDVNPRW-- 246

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l+ ++++a r+++L+ndlL l+++ea
AE004091_5 247 ----------LRALQQMQQQAGRMQNLLNDLLLLAKLEAT 276

AE004091_4980: domain 1 of 1, from 506 to 571: score 76.9, E = 2.5e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fla++sHE+RTPL++I+g+aelL+e + l+e +
AE004091_4 506 AKSRFLATMSHEIRTPLNGILGMAELLRE---------ASLGERD-- 541

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ + ++e ll+++n++L ++r+e+
AE004091_4 542 ----------RQRLRALATAGEGLLAILNEVLHFARLEEA 571

AE004091_3946: domain 1 of 1, from 709 to 775: score 76.6, E = 3.1e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ fla++sHE+RTP++a++g +el+l+ ++e + +
AE004091_3 709 AKTTFLATMSHEIRTPMNAVIGILELALK--------RAETGRVD-- 745

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r +e+++ +a++ll+Li d+Ld++rie+g
AE004091_3 746 ----------RSSIEIAYASAKSLLELIGDILDIARIESG 775

AE004091_1440: domain 1 of 1, from 243 to 309: score 76.5, E = 3.3e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f a+++HELRTPLt ++g ++++l e+s e+
AE004091_1 243 RLESFNADVAHELRTPLTNLIGQTQVALS---------RERSGEH-- 278

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+e l++ l+e+erl++++nd+L l+r+++g
AE004091_1 279 ---------YEEVLQSNLEELERLRAIVNDMLFLARADQG 309

AE004091_3045: domain 1 of 1, from 247 to 313: score 74.7, E = 1.1e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTP++a++g +el l l +eqr
AE004091_3 247 AKSVFLATMSHEIRTPMNAVIGILELVLQ----------RLAPEQRE 283

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r le+++++a +l+ Li d+Ld ++ie+g
AE004091_3 284 ----------RASLEVAYEAAGSLQLLIGDILDVAKIESG 313

AE004091_1638: domain 1 of 1, from 650 to 718: score 73.3, E = 2.7e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+s +la++sH+LRTPLta+rg ++ Ll+ + ++ ++ +r
AE004091_1 650 LRSALLASVSHDLRTPLTAMRGSIDSLLALG-------EAIPPADR- 688

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re+le+ ++eaerl+r i++lLd++r+++g
AE004091_1 689 ----------RELLESTRDEAERLDRYIQNLLDMTRLGHG 718

AE004091_4546: domain 1 of 1, from 309 to 375: score 72.9, E = 3.4e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++a+++HE+R+PL aI+ +a+lL+e ++el++++
AE004091_4 309 GLGRLTAGIAHEIRNPLGAISHAAQLLQE--------SEELDAPD-- 345

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+++++i+++++r++ i+++L+lsr ++
AE004091_4 346 ----------RRLTQIIQDQSKRMNLVIENVLQLSRRRQA 375

AE004091_2811: domain 1 of 1, from 225 to 291: score 72.5, E = 4.5e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s f a+++HELRTPLt++++ +++ l ++s e+
AE004091_2 225 RLSAFSADIAHELRTPLTSLLTQTQVVLS---------RPRSLED-- 260

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yre+l+ l+e+erl +++nd+L l+++++g
AE004091_2 261 ---------YREALHGNLEELERLTAMVNDMLLLAKADHG 291

AE004091_5482: domain 1 of 1, from 375 to 443: score 69.3, E = 3.8e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+sef+ +sHELRTP+t+++++ +lL+e + + ++e r
AE004091_5 375 VRSEFVLRASHELRTPVTGMQMAFSLLRE--------RLDFPAESRE 413

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++t+++e rl LindlL +sr ++g
AE004091_5 414 ----------ADLIQTVDEEMSRLVLLINDLLNFSRYQTG 443

AE004091_0465: domain 1 of 1, from 255 to 320: score 68.0, E = 8.4e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l HEL+ PL+aIrg+aelL e+++eqr
AE004091_0 255 YVERYVHTLTHELKSPLAAIRGAAELLDG----------EMPAEQR- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++ i e+erl++Li++lL l++ e+
AE004091_0 291 ----------ARFVGNIAGESERLQQLIERLLSLAQVEQR 320

AE004091_1160: domain 1 of 1, from 222 to 287: score 65.4, E = 4.7e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e+++++sHELRTP++ +r+ +e++++ +e +
AE004091_1 222 VQREMVRAVSHELRTPVARLRFGLEMIET---------AETDGAR-- 257

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+yle ++++++ l++L++++L+++r+e+g
AE004091_1 258 ----------LKYLEGMDNDIQDLDKLVDEMLTYARLEQG 287

AE004091_0758: domain 1 of 1, from 244 to 309: score 65.4, E = 4.8e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s f+a+++HELRTPL+a+++ +el l+ e+ +e
AE004091_0 244 RQSHFIADAAHELRTPLAALKARLELGLR----------EQEPEA-- 278

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+r let + ++rl +L n+lL l+rie+g
AE004091_0 279 ---------WRSTLETTAKNTDRLIHLANQLLSLARIESG 309

AE004091_5122: domain 1 of 1, from 131 to 196: score 64.9, E = 6.6e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++l+HE+++PL +Irg+a+lL + el+ee +
AE004091_5 131 TTKLLVRGLAHEIKNPLGGIRGAAQLLSR----------ELPEESL- 166

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++y+++i++ea+rl++L++++L ++ +
AE004091_5 167 ----------KDYTNVIIEEADRLRNLVDRMLGSNKLPNL 196

AE004091_3974: domain 1 of 1, from 418 to 483: score 64.5, E = 8.3e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+efla++ HELRTP+++++g +el+++ +++ e
AE004091_3 418 LKDEFLATVTHELRTPMSGVIGSLELMQT---------VPMDVEL-- 453

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ey +t+ +a+ + r++nd+L l ++ag
AE004091_3 454 ----------AEYQRTAAGSARDMMRMVNDILALIELQAG 483

AE004091_4380: domain 1 of 1, from 211 to 277: score 64.2, E = 1.1e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + f++++sHELRTPL +I + +elL e ++ l++
AE004091_4 211 REQLFTSDVSHELRTPLMVIATSCELLAE--------EPSLGPRA-- 247

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r le++ +++e +++L++ +L l+r++ g
AE004091_4 248 ----------RGQLERMTKATEEMRDLVQTFLLLARAQKG 277

AE004091_4884: domain 1 of 1, from 243 to 309: score 63.5, E = 1.6e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f a+l+HE+RTP+ +++g+ +++l+ +++s e+
AE004091_4 243 RLQQFSADLAHEIRTPIGSLMGHGQVALR---------QPRSNEE-- 278

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ ++ + ++e+er+ r+++ +L l+r++
AE004091_4 279 ---------YQALIASNQEELERIARMVESILFLARADDV 309

AE004091_2584: domain 1 of 1, from 607 to 673: score 62.6, E = 2.8e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fl+++sHE+RTPL+a++g+ el l++++k + l+ +
AE004091_2 607 AKSVFLSTMSHEIRTPLNAVIGLQELVLKKGEK-----GVLDLDS-- 646

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l++++++a+ ll L+ ++Ldlsrie+g
AE004091_2 647 -------------LSIAQEAAQGLLLLLGNILDLSRIESG 673

AE004091_1100: domain 1 of 1, from 181 to 247: score 62.6, E = 3e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++a+l+H++RTPL+a ++ya L e ++l+ +q+
AE004091_1 181 ALGRMVASLAHQIRTPLSAALLYAGHLSE---------QALPTDQQ- 217

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ ++++ ++ l+++++d+L ++r e +
AE004091_1 218 ----------QRFAGRLKERLHELEHQVRDMLVFARGELP 247

AE004091_1398: domain 1 of 1, from 179 to 244: score 60.7, E = 1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks++la +sH+LR+P+++I +++ L++ + l++e+
AE004091_1 179 EKSRLLAQASHDLRQPIHSIGLFTACLRD---------ARLGDEE-- 214

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++++ i+r++ ++L + +Ldl +++g
AE004091_1 215 ----------RRLVDNIDRSLLNVSQLFRSILDLYTLDNG 244

AE004091_4117: domain 1 of 1, from 503 to 566: score 60.0, E = 1.6e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++++a l H+LR+PL +I+++a lL +++r
AE004091_4 503 MRQRLIAVLGHDLRNPLQSISMAAALLSS-------------SDTRT 536

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+ + i ++ r++rL++++Ld+sr+++g
AE004091_4 537 ----------TELRQHISASSSRMERLVSQILDMSRLQSG 566

AE004091_3207: domain 1 of 1, from 227 to 291: score 56.2, E = 2e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELR PL+ +r ++ l+++ + +e r
AE004091_3 227 SQRQLLRDVSHELRSPLARLRIALALAER-----------AEPEAR- 261

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ ++++e +rl++Li ++L l+r++a+
AE004091_3 262 ----------AQMWPRLEQECDRLEALIGEILALARLDAE 291

AE004091_3272: domain 1 of 1, from 798 to 864: score 55.4, E = 3.3e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k++fla++sH+L +PL+a r+++ +L +++ + ++
AE004091_3 798 SKTRFLAAVSHDLMQPLNAARLFSAALAH---------QDALPGEV- 834

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++++ +++++++ ++Li dlLd+sr+e+g
AE004091_3 835 ----------RDLVQHLDSSLRSAEDLITDLLDISRLESG 864

AE004091_1978: domain 1 of 1, from 513 to 579: score 54.8, E = 4.6e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k++fla++sH+L +PL+a r+++++L+e ++ ++ +
AE004091_1 513 SKTKFLAAVSHDLLQPLNAARLFTSALQE--------RGSATRDN-- 549

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ i +++e ++L+ l d+s+++ag
AE004091_1 550 ----------EALVNNISHSLEDVENLLGTLVDISKLDAG 579

AE004091_3079: domain 1 of 1, from 235 to 299: score 52.4, E = 2.3e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++fl+++sHELRTPL++I +++elL + + +
AE004091_3 235 REERFLRYASHELRTPLAVIGMNLELLDQ---------PGRAPSP-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+l++i+r+a ++++ + lL lsr +
AE004091_3 271 -----------HALQRIRRSALGMQQMTETLLWLSRESGE 299

AE004091_0932: domain 1 of 1, from 233 to 292: score 52.3, E = 2.4e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++l++lsHELRTPL+ ++ +ae l
AE004091_0 233 LQRQLLRDLSHELRTPLARLQVAAEGTLS------------------ 261

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + e++++e++ +++L+++ L+l++++++
AE004091_0 262 ---------AQLLRERLEQEVQGMQQLVDNTLELAWMDTE 292

AE004091_4775: domain 1 of 1, from 239 to 304: score 51.4, E = 4.2e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++++HE+RTPL+++r++a+++l+ +e + +
AE004091_4 239 AERRLTSDAAHEIRTPLASLRTHAQVALR---------SEDPKAH-- 274

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l + r++er++ L +++L l+r++
AE004091_4 275 ----------ARGLLQVSRSVERISTLMEQILLLARLDGD 304

AE004091_1800: domain 1 of 1, from 208 to 273: score 51.4, E = 4.2e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++ ++sHELRTP++ +++ +e L + ++e r
AE004091_1 208 NQRELTNAVSHELRTPISRLSFELEQLNK----------QVDAEVR- 243

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++e ++ ++ l++++++lL+++r+e+g
AE004091_1 244 ----------HDLIEDMRADLGELEEMVSELLTYARLEHG 273

AE004091_5197: domain 1 of 1, from 222 to 282: score 50.3, E = 8.8e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ +la++sH+LRTPLt +r+ +elL e +e
AE004091_5 222 ERELMLAGVSHDLRTPLTRLRLSLELLPE---------SE------- 252

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re++e ++r++e ++++++++L + r +
AE004091_5 253 ----------REMVEDMIRDIEDMDAILDQFLAFIRDGRD 282

AE004091_4723: domain 1 of 1, from 756 to 822: score 49.2, E = 1.9e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++++a+++HE+ +P+t+I +a+ L+e + e + e
AE004091_4 756 SIGRLAAGVAHEIGNPITGIACLAQNLRE--------EREGDGEL-- 792

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+ e il++++r +r+++ l+ ++ ++
AE004091_4 793 ----------TEISEQILDQTKRVSRIVQSLMSFAHSGSH 822

AE004091_2688: domain 1 of 1, from 234 to 293: score 48.4, E = 3.1e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ +l++lsHELRTPL+ +r + + el++eq+
AE004091_2 234 QQRLLLRTLSHELRTPLARLRIAHDS-------------ELPPEQL- 266

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++re+ ++rL++d Ldl++++++
AE004091_2 267 -------------RQRLDREIGDMQRLLEDTLDLAWMDTE 293

AE004091_2481: domain 1 of 1, from 225 to 289: score 48.3, E = 3.3e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++++ +++HELR PLtaI+++++++++ te + +
AE004091_2 225 RERRLTGDAAHELRSPLTAIKTHLQVARM---------TEGAAAE-- 260

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l +++ a+rl r +++lL l+r e
AE004091_2 261 -----------QALAHAEEGADRLHRTLDQLLLLARVEGS 289

AE004091_2179: domain 1 of 1, from 330 to 396: score 46.5, E = 1.1e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ ++ +++H++++ Lt+I+g + lL++ l+ +qr
AE004091_2 330 SLGHLTGGVAHDFNNLLTVIIGSLGLLKK----------RLPGDQRT 366

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+ +l++a+r +L +++L ++r +
AE004091_2 367 ----------ADLLQNALEAAQRGANLTQRMLSFARKQRL 396

AE004091_2525: domain 1 of 1, from 249 to 315: score 45.5, E = 2e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f +l+HELR P+ ++ ++Ll ++++
AE004091_2 249 QLSQFSDDLAHELRAPICNLLVRNQVLLS---------QHRDGAA-- 284

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yre+le+ +e+erl+r++ d+L l + +++
AE004091_2 285 ---------YREALESNAEELERLSRIVTDMLFLVQVDNP 315

AE004091_1245: domain 1 of 1, from 496 to 561: score 44.4, E = 4.3e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++++ +++H++++ Lt I++ +el+++ ++
AE004091_1 496 MVGQLTGGIAHDFNNLLTPIMASLELIRR---------RLDDARS-- 531

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++ +l++aer ++L+ +lL+++r ++
AE004091_1 532 ----------TDLIDGALQSAERARNLVGRLLTFARRQTL 561

AE004091_5510: domain 1 of 1, from 362 to 430: score 44.0, E = 5.5e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++++ a+l+HE+++PLta r+ + L+ ld + + +e
AE004091_5 362 ALGQMSAALAHEINQPLTAQRMQLASLRLLLD------AGRHDEA-- 400

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++l +i++ +er+ +L l +++r ag
AE004091_5 401 ----------RQALPRIDQMLERMAALTGHLKTFARKSAG 430

AE004091_1994: domain 1 of 1, from 202 to 267: score 43.5, E = 7.4e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k++ la++sH+L +PL+a r+++++L+e l++ +
AE004091_1 202 SKDKYLAAASHDLLQPLNAARLLVDTLRE---------RGLPAAE-- 237

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++e+ + ++e + L+ dlL+++r+++
AE004091_1 238 ----------LQLVERTHLALEGAETLLTDLLEIARLDQS 267

AE004091_5163: domain 1 of 1, from 378 to 446: score 38.2, E = 2.5e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ + a++sHEL++PL+aIr ya+ ++ ld + ++e+
AE004091_5 378 ALGTMSASISHELNQPLAAIRSYADNARVLLD------HQRTEDA-- 416

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r le i + + r+ ++i l ++r
AE004091_5 417 ----------RGNLEQISDLTTRMASIIAHLKAYARGARR 446

AE004091_4293: domain 1 of 1, from 690 to 760: score 36.3, E = 8e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++e++++l+HE ++PL+++r+++ ++ +++ + l+ + +
AE004091_4 690 SLGEMVSGLAHEVKQPLHVLRMTLFNMRQRMN-----SVGLDGDYL- 730

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e le+++ ++ r +rL++ l +sr a
AE004091_4 731 ----------GEKLERMDAQVLRVDRLVSHLGVFSRKSAL 760

AE004091_3192: domain 1 of 1, from 270 to 313: score 35.2, E = 1.7e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++++++sH+LRTP+t +r+ +elL++ + l e+
AE004091_3 270 ERGQLFSAISHDLRTPITRLRLRVELLED---------ERLQEKF-- 305

peLRledpeyreyletil<-*
+ l+ ++
AE004091_3 306 ----------GRDLDELE 313

AE004091_1338: domain 1 of 1, from 407 to 475: score 32.6, E = 9.1e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ +++HEL++PL+a+r+++ ++l + e++
AE004091_1 407 VIGQMSTSIAHELNQPLAALRTLSGNTVRFL-------QRGKLETA- 445

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l ti + ++r+ r+ l+ ++r
AE004091_1 446 ----------STNLATINELVDRMGRITASLRAFARRSDD 475

AE004091_4494: domain 1 of 1, from 207 to 273: score 31.7, E = 1.6e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +a+++HEL TPL++++ ++ L+ + ++++
AE004091_4 207 AVATQAAGAAHELGTPLATMSVLLNELRQ---------ERPQDPTL- 243

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e l ++++++++ + +++l + ++
AE004091_4 244 ----------QEDLALLQEQVKQCKHTLQQLVRAAEADRR 273

AE004091_4197: domain 1 of 1, from 526 to 599: score 29.5, E = 7e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkv.lagdtelseeqr
++e++++++HE+++PL+a++ ya++ +++l l++ +e+
AE004091_4 526 TLGELASGIAHEINQPLAAVMNYASTSQRYL--AvLGSQPEAAGRV- 569

lpeLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e l +i + a + + i +l+ + r ++
AE004091_4 570 -----------AEGLARIGEHAGHAAEVIKRLRAFLRKGQR 599

AE004091_1182: domain 1 of 1, from 238 to 300: score 27.2, E = 3.1e-07
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + l +l+H L+TPL++++g + L e ++ + eq
AE004091_1 238 RYRHSLGDLAHSLKTPLAVLQGVGDQLAE---------EPGNREQ-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ ++er++++i L+ + ++
AE004091_1 274 -------------VRVLQGQIERMSQQIGYQLQRASLRKS 300


Histogram of all scores:
score obs exp (one = represents 18 sequences)
----- --- ---
-15 1 0|=
-14 3 0|=
-13 36 4|*=
-12 158 127|=======*=
-11 378 660|===================== *
-10 798 1224|============================================= *
-9 1048 1264|==========================================================*
-8 1039 946|====================================================*=====
-7 753 596|=================================*========
-6 559 343|===================*============
-5 315 188|==========*=======
-4 165 100|=====*====
-3 101 53|==*===
-2 73 27|=*===
-1 37 14|*==
0 23 7|*=
1 12 3|*
2 5 2|*
3 3 1|*
4 2 0|=
5 0 0|
6 1 0|=
7 2 0|=
> 8 56 -|====


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 805.8693
P(chi-square) = 0

Total sequences searched: 5568

Whole sequence top hits:
tophits_s report:
Total hits: 50
Satisfying E cutoff: 50
Total memory: 22K

Domain top hits:
tophits_s report:
Total hits: 49
Satisfying E cutoff: 49
Total memory: 40K


Acknowledgements:

This research is funded by:

Developed by: