Acidobacteria Actinobacteria Alphaproteobacteria
Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria
Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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2 accessions found for   

Data for AE006468  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AE006468.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AE006468_2874 CDS_3106519-3109275 100.2 5.3e-28 1
AE006468_0388 CDS_451554-452849 90.2 3.6e-25 1
AE006468_1352 CDS_1479598-1476836 82.3 6e-23 1
AE006468_2208 CDS_2373593-2370747 81.3 1.2e-22 1
AE006468_3233 CDS_3492828-3490492 78.9 5.5e-22 1
AE006468_3722 CDS_4026452-4029187 73.8 1.6e-20 1
AE006468_2494 CDS_2707616-2706174 69.6 2.4e-19 1
AE006468_3935 CDS_4269749-4268376 67.0 1.3e-18 1
AE006468_2070 CDS_2223137-2224540 63.5 1.3e-17 1
AE006468_4038 CDS_4388436-4389833 62.5 2.4e-17 1
AE006468_0683 CDS_769697-767013 61.1 6.4e-17 1
AE006468_3882 CDS_4215324-4214275 60.3 1.1e-16 1
AE006468_4441 CDS_4844922-4846346 59.8 1.4e-16 1
AE006468_1063 CDS_1183644-1182280 57.5 6.6e-16 1
AE006468_3088 CDS_3341454-3342803 55.9 1.9e-15 1
AE006468_3399 CDS_3659609-3658257 54.9 3.6e-15 1
AE006468_4152 CDS_4533709-4532639 47.7 4e-13 1
AE006468_1427 CDS_1547706-1546405 47.4 4.7e-13 1
AE006468_2705 CDS_2933774-2932359 36.6 5.4e-10 1
AE006468_2333 CDS_2510504-2508498 35.3 1.3e-09 1
AE006468_1346 CDS_1471349-1473127 31.5 1.5e-08 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AE006468_2874 1/1 292 357 .. 1 87 [] 100.2 5.3e-28
AE006468_0388 1/1 203 269 .. 1 87 [] 90.2 3.6e-25
AE006468_1352 1/1 395 460 .. 1 87 [] 82.3 6e-23
AE006468_2208 1/1 469 534 .. 1 87 [] 81.3 1.2e-22
AE006468_3233 1/1 282 347 .. 1 87 [] 78.9 5.5e-22
AE006468_3722 1/1 444 509 .. 1 87 [] 73.8 1.6e-20
AE006468_2494 1/1 253 321 .. 1 87 [] 69.6 2.4e-19
AE006468_3935 1/1 238 300 .. 1 87 [] 67.0 1.3e-18
AE006468_2070 1/1 240 304 .. 1 87 [] 63.5 1.3e-17
AE006468_4038 1/1 246 312 .. 1 87 [] 62.5 2.4e-17
AE006468_0683 1/1 663 730 .. 1 87 [] 61.1 6.4e-17
AE006468_3882 1/1 129 186 .. 1 79 [. 60.3 1.1e-16
AE006468_4441 1/1 255 320 .. 1 87 [] 59.8 1.4e-16
AE006468_1063 1/1 236 302 .. 1 87 [] 57.5 6.6e-16
AE006468_3088 1/1 236 302 .. 1 87 [] 55.9 1.9e-15
AE006468_3399 1/1 233 293 .. 1 87 [] 54.9 3.6e-15
AE006468_4152 1/1 142 202 .. 1 87 [] 47.7 4e-13
AE006468_1427 1/1 211 271 .. 1 87 [] 47.4 4.7e-13
AE006468_2705 1/1 246 311 .. 1 87 [] 36.6 5.4e-10
AE006468_2333 1/1 447 515 .. 1 87 [] 35.3 1.3e-09
AE006468_1346 1/1 357 426 .. 1 87 [] 31.5 1.5e-08

Alignments of top-scoring domains:
AE006468_2874: domain 1 of 1, from 292 to 357: score 100.2, E = 5.3e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ tel++ q
AE006468_2 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------TELNPTQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ti+r+a+ ll++ind+Ld+s++eag
AE006468_2 328 ----------RDHLNTIERSANNLLAIINDVLDFSKLEAG 357

AE006468_0388: domain 1 of 1, from 203 to 269: score 90.2, E = 3.6e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e+++e ++l +r
AE006468_0 203 ARRNFFANVSHELRTPLTVLQGYLEMMQE---------QALEGATR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t+++++ r++ L+ +lL+ls+iea
AE006468_0 240 ----------EKALHTMREQTYRMEGLVKQLLTLSKIEAA 269

AE006468_1352: domain 1 of 1, from 395 to 460: score 82.3, E = 6e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks l +sHELRTP+++++g++elL++ t+l+ eq
AE006468_1 395 RKSIHLTVISHELRTPMNGVLGAIELLQT---------TPLNIEQ-- 430

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + +t+++++ +ll++in+lLd+srie+g
AE006468_1 431 ----------QGLADTARNCTLSLLAIINNLLDFSRIESG 460

AE006468_2208: domain 1 of 1, from 469 to 534: score 81.3, E = 1.2e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
AE006468_2 469 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPKGV-- 504

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++ + +++ ll++i+d+Ld+s+ie++
AE006468_2 505 ----------ERLVTAMNNSSSLLLKIISDILDFSKIESE 534

AE006468_3233: domain 1 of 1, from 282 to 347: score 78.9, E = 5.5e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ t+l++eq
AE006468_3 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TDLTAEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
AE006468_3 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

AE006468_3722: domain 1 of 1, from 444 to 509: score 73.8, E = 1.6e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL +I+g+++lL + ++ +
AE006468_3 444 AKSTFLAAMSHEIRTPLYGILGTVQLLAD-----------KPLMT-- 477

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+yr+ l+ i +++e+ll+++nd+Ld+s ie g
AE006468_3 478 --------NYRDDLQAINDSGESLLAILNDILDYSAIEVG 509

AE006468_2494: domain 1 of 1, from 253 to 321: score 69.6, E = 2.4e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +fl++lsHEL+TPL+++r +elL +++ ++l++eq
AE006468_2 253 QRHQFLRHLSHELKTPLASMREGTELLADQV------VGPLTPEQ-- 291

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e +++++++++ l++Li++lLd+ r
AE006468_2 292 ----------KEVVDILDDSSRNLQKLIEQLLDYNRKLVD 321

AE006468_3935: domain 1 of 1, from 238 to 300: score 67.0, E = 1.3e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
AE006468_3 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RGGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr ++
AE006468_3 274 -------------LERIETEAQRLDSMINDLLVMSRNQQK 300

AE006468_2070: domain 1 of 1, from 240 to 304: score 63.5, E = 1.3e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPL+++rg +e++++++ ++e
AE006468_2 240 MRRDFMADISHELRTPLAVLRGELEAIQDGV-------RQFTPES-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ e+ l +L++dl +ls ++g
AE006468_2 278 -------------VTSLQAEVGTLTKLVDDLHQLSLSDEG 304

AE006468_4038: domain 1 of 1, from 246 to 312: score 62.5, E = 2.4e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE+R+PL++I+g+a+ e +t+++ e
AE006468_4 246 AMGHLAAGVAHEIRNPLSSIKGLAKYFAE--------RTPAGGES-- 282

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+ +++ +ea+rl+r +++lL+l + +
AE006468_4 283 ----------HELAQVMAKEADRLNRVVSELLELVKPAHL 312

AE006468_0683: domain 1 of 1, from 663 to 730: score 61.1, E = 6.4e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l + +++++
AE006468_0 663 IRNALLAALSHDLRTPLTVLFGQAEILTLDL-------ASAGSPH-- 700

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + i++ + rL+n+lLd++ri++g
AE006468_0 701 ----------ARQASEIRQHILNTTRLVNNLLDMARIQSG 730

AE006468_3882: domain 1 of 1, from 129 to 186: score 60.3, E = 1.1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
AE006468_3 129 AARDLVRGLAHEIKNPLGGLRGAAQLLSK----------ALPDPAL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
AE006468_3 165 ----------TEYTKVIIEQADRLRNLVDRLL 186

AE006468_4441: domain 1 of 1, from 255 to 320: score 59.8, E = 1.4e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++ + +l HEL+ PL+aIrg+ae+L+e ++ +
AE006468_4 255 EIEQYVYALTHELKSPLAAIRGAAEILRE---------GPPADVV-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++e il + r+++L++ lL +r+e+
AE006468_4 291 ----------TRFTENILAQNTRMQALVETLLRQARLENR 320

AE006468_1063: domain 1 of 1, from 236 to 302: score 57.5, E = 6.6e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ +l+HELRTP++ ++g +++l +e+s+e+
AE006468_1 236 RLNQFADDLAHELRTPVNILLGKNQVMLS---------QERSAEE-- 271

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+++l ++e+e l+rL +++L l+r+e++
AE006468_1 272 ---------YQQALVDNIEELEGLSRLTENILFLARAEHQ 302

AE006468_3088: domain 1 of 1, from 236 to 302: score 55.9, E = 1.9e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PL+a++ +e+++ + ++ r
AE006468_3 236 RERRFTSDAAHELRSPLAALKVQTEVAQL---------SGDDPLSR- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l ++ ++r rL+++lL+lsr+++
AE006468_3 273 ----------DKALTQLHAGIDRATRLVDQLLTLSRLDSL 302

AE006468_3399: domain 1 of 1, from 233 to 293: score 54.9, E = 3.6e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e e+
AE006468_3 233 DRTLLMAGVSHDLRTPLTRIRLATEMMGE--------------ED-- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
AE006468_3 264 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 293

AE006468_4152: domain 1 of 1, from 142 to 202: score 47.7, E = 4e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+++r+++elL + t+
AE006468_4 142 NERLFTADVAHELRTPLSGVRLHLELLSK---------TH------- 172

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++ ++++ + +++lL+l+r ++
AE006468_4 173 ----------NVDVAPLIARLDQMMDSVSQLLQLARVGQS 202

AE006468_1427: domain 1 of 1, from 211 to 271: score 47.4, E = 4.7e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ ++ l++++
AE006468_1 211 SKKQLIDGIAHELRTPLVRLRYRLEMSEN-----------LTPPE-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
AE006468_1 245 -------------SQALNRDIGQLEALIEELLTYARLDRP 271

AE006468_2705: domain 1 of 1, from 246 to 311: score 36.6, E = 5.4e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f a++sH+L+TPL+++++ a ++l+ + + +
AE006468_2 246 RQERFSADASHQLKTPLAVLKTQAAVALA----------SQHPHH-- 280

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e l+ + +++ +L ++lL+ls +
AE006468_2 281 ---------WYESLQAMSVTLDSTIQLTERLLQLSAVKHK 311

AE006468_2333: domain 1 of 1, from 447 to 515: score 35.3, E = 1.3e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l+HE+++PL+a+++y+ ++ + a+++ +s +
AE006468_2 447 VVGQTMTTLAHEINQPLNALSMYLFTAGR------AIEQGQSGQA-- 485

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r l +++ ++r++++i+ l++++r +
AE006468_2 486 ----------RNTLTKAEGLINRIDAIIRSLRQFTRRAEL 515

AE006468_1346: domain 1 of 1, from 357 to 426: score 31.5, E = 1.5e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++++ +HEL++PL+aIr ya+ +l +l +++e++ l
AE006468_1 357 VLGEMTSGFAHELNQPLSAIRHYAQGCLIRL-------RAADEQHPL 396

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+le i+++a+r + +++l+ +g
AE006468_1 397 ----------LPALEQIDQQAQRGADTLRNLRHWVSQAQG 426


Histogram of all scores:
score obs exp (one = represents 15 sequences)
----- --- ---
-14 18 0|==
-13 64 3|*====
-12 220 101|======*========
-11 487 527|================================= *
-10 745 979|================================================== *
-9 850 1011|========================================================= *
-8 762 756|==================================================*
-7 524 477|===============================*===
-6 322 274|==================*===
-5 219 150|=========*=====
-4 95 80|=====*=
-3 38 42|==*
-2 30 22|=*
-1 26 11|*=
0 14 6|*
1 7 3|*
2 6 1|*
3 2 0|=
> 4 23 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 299.5804
P(chi-square) = 0

Total sequences searched: 4452

Whole sequence top hits:
tophits_s report:
Total hits: 21
Satisfying E cutoff: 21
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 21
Satisfying E cutoff: 21
Total memory: 29K


Acknowledgements:

This research is funded by:

Developed by: