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2 accessions found for Brucella melitensis bv. 1 str. 16M  

Data for AE008917  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AE008917.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AE008917_1324 CDS_1374959-1377310 90.3 1.5e-25 1
AE008917_0416 CDS_437528-435087 89.7 2.3e-25 1
AE008917_1623 CDS_1672000-1670762 85.6 3.3e-24 1
AE008917_2034 CDS_2097304-2095499 72.5 1.7e-20 1
AE008917_2026 CDS_2091587-2089281 69.6 1.1e-19 1
AE008917_1356 CDS_1412570-1411263 63.3 6.7e-18 1
AE008917_0864 CDS_891518-892660 55.3 1.3e-15 1
AE008917_1327 CDS_1384214-1382811 48.8 8.9e-14 1
AE008917_1605 CDS_1651656-1655573 45.0 1.1e-12 1
AE008917_0866 CDS_894292-896547 44.3 1.7e-12 1
AE008917_1815 CDS_1854162-1852939 40.1 2.5e-11 1
AE008917_0946 CDS_983868-981565 39.5 3.9e-11 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AE008917_1324 1/1 543 612 .. 1 87 [] 90.3 1.5e-25
AE008917_0416 1/1 573 642 .. 1 87 [] 89.7 2.3e-25
AE008917_1623 1/1 174 241 .. 1 87 [] 85.6 3.3e-24
AE008917_2034 1/1 364 429 .. 1 87 [] 72.5 1.7e-20
AE008917_2026 1/1 536 604 .. 1 87 [] 69.6 1.1e-19
AE008917_1356 1/1 154 223 .. 1 87 [] 63.3 6.7e-18
AE008917_0864 1/1 135 199 .. 1 87 [] 55.3 1.3e-15
AE008917_1327 1/1 240 306 .. 1 87 [] 48.8 8.9e-14
AE008917_1605 1/1 798 863 .. 1 87 [] 45.0 1.1e-12
AE008917_0866 1/1 502 573 .. 1 87 [] 44.3 1.7e-12
AE008917_1815 1/1 186 252 .. 1 87 [] 40.1 2.5e-11
AE008917_0946 1/1 389 455 .. 1 87 [] 39.5 3.9e-11

Alignments of top-scoring domains:
AE008917_1324: domain 1 of 1, from 543 to 612: score 90.3, E = 1.5e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
akseflan+sHELRTPL+aI+g++e+++++ + ++l+++
AE008917_1 543 AKSEFLANMSHELRTPLNAIIGFSEMIQAGTF------GPLGSDR-- 581

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ey++ i+ +++ ll+ ind+Ld+s+ieag
AE008917_1 582 ---------YEEYINDIHTSGNFLLNVINDILDMSKIEAG 612

AE008917_0416: domain 1 of 1, from 573 to 642: score 89.7, E = 2.3e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k+efla +sHE+RTPL+aI+g++el+ + + ++ + +
AE008917_0 573 QKTEFLARISHEIRTPLNAIIGFSELMAD------EKFGPIGNDR-- 611

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr+yl+ i r++++ l+L+ndlLd+s+ieag
AE008917_0 612 ---------YRDYLRDINRSGNHVLALVNDLLDISKIEAG 642

AE008917_1623: domain 1 of 1, from 174 to 241: score 85.6, E = 3.3e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f+an+sHELRTPL+++rg++e+L+ +++++ ++
AE008917_1 174 MRSDFIANASHELRTPLASLRGFIETLQG---------PARNDAAAR 211

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l++++++aer++rLi+dlL lsr+e
AE008917_1 212 ----------DRFLDIMQKQAERMSRLIDDLLSLSRLEMR 241

AE008917_2034: domain 1 of 1, from 364 to 429: score 72.5, E = 1.7e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + f+a++sHEL++PLt++r ++e+L ++++e r
AE008917_2 364 AIESFAADVSHELKNPLTSLRSAVETLPL----------AKTDESR- 399

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l++i+++++rl+rLi d+ d sr++a+
AE008917_2 400 ----------KRLLDVIQHDVRRLDRLITDISDASRLDAE 429

AE008917_2026: domain 1 of 1, from 536 to 604: score 69.6, E = 1.1e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k++f+ ++s ELR PLt I+g++elL++ + + l+e q
AE008917_2 536 IKNDFVQHVSYELRSPLTNIIGFTELLQT------PAFGSLNERQ-- 574

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
eyl+ i ++ ll ++nd+Ldl+ +ag
AE008917_2 575 ----------LEYLDHISTSSSVLLTIVNDILDLATVDAG 604

AE008917_1356: domain 1 of 1, from 154 to 223: score 63.3, E = 6.7e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+++la++sHELRTPL++I+g++++L + ++l ++ +
AE008917_1 154 GKGRLLATVSHELRTPLNSIIGFSDMLTH------EIGGKLASDRQ- 193

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
rey i++++++ll+L+n +Ld sr+e+g
AE008917_1 194 ----------REYAGLIHQSGHYLLELVNAVLDNSRLETG 223

AE008917_0864: domain 1 of 1, from 135 to 199: score 55.3, E = 1.3e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + ++++l+HE+++PL++Irg+a+lL+ s+e+
AE008917_0 135 SVTGLASMLAHEIKNPLSGIRGAAQLLEQ----------VVSDED-- 169

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r + + i +e++r+ +L++++ +s +
AE008917_0 170 ----------RALARLITEETDRIVSLVDRMEVFSDERPI 199

AE008917_1327: domain 1 of 1, from 240 to 306: score 48.8, E = 8.9e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + n++H+L+TPLt +r ae +l +e+ e++
AE008917_1 240 GLKQVSDNIAHDLKTPLTRLRNRAEEALG---------GEKVEPE-- 275

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr +le i+ e+++l r n +L +sr+eag
AE008917_1 276 ---------YRAALEDIIGESDQLIRTFNAILMISRLEAG 306

AE008917_1605: domain 1 of 1, from 798 to 863: score 45.0, E = 1.1e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k++fla++ H++ +PL+a r+y+ +L e +l+ ++
AE008917_1 798 GKTRFLAAAGHDILQPLNAARLYSTALAE----------KLGRSET- 833

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+ + i++++e ++++ +Ld+sr+++g
AE008917_1 834 ----------SEFARNIDSSLEAVEAILGMVLDISRLDTG 863

AE008917_0866: domain 1 of 1, from 502 to 573: score 44.3, E = 1.7e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + ++ ++HE+++PLt I++ ae +++++ ++ + + e
AE008917_0 502 AWADVARRIAHEIKNPLTPIQLSAERIRRRY----GKVITEDREV-- 542

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + ++ti+r++ + r+++++ ++r+ ++
AE008917_0 543 ---------FDQCTDTIIRQVGDIGRMVDEFSAFARMPQP 573

AE008917_1815: domain 1 of 1, from 186 to 252: score 40.1, E = 2.5e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HEL TPL++I + ++ +++ +++++
AE008917_1 186 ALDGLAAAAAHELGTPLATIALVVKEMQR--------AHTKDPGL-- 222

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e + ++++++r+++++++l ls +++
AE008917_1 223 ----------EEDIALLHSQTQRCREILQRLTSLSSEGEE 252

AE008917_0946: domain 1 of 1, from 389 to 455: score 39.5, E = 3.9e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++ +++H++++ LtaI++ ++lLl++ + +s++
AE008917_0 389 AVGQLAGGIAHDFNNVLTAIIMSSDLLLTN--------HRASDPS-- 425

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ i++ a+r +L+++lL +sr ++
AE008917_0 426 ----------FPDIMNIKQNANRAASLVRQLLAFSRRQTL 455


Histogram of all scores:
score obs exp (one = represents 7 sequences)
----- --- ---
-14 6 0|=
-13 27 1|*===
-12 121 47|======*===========
-11 220 244|================================ *
-10 377 452|====================================================== *
-9 406 467|==========================================================*
-8 332 350|================================================ *
-7 243 220|===============================*===
-6 135 126|=================*==
-5 81 69|=========*==
-4 48 37|=====*=
-3 21 19|==*
-2 12 10|=*
-1 7 5|*
0 4 2|*
1 1 1|*
2 0 0|
3 2 0|=
> 4 16 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 148.8158
P(chi-square) = 2.601e-26

Total sequences searched: 2059

Whole sequence top hits:
tophits_s report:
Total hits: 12
Satisfying E cutoff: 12
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 12
Satisfying E cutoff: 12
Total memory: 25K


Acknowledgements:

This research is funded by:

Developed by: