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1 accessions found for Methanosarcina acetivorans C2A  

Data for AE010299  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AE010299.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
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Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AE010299_1962 CDS_2498282-2495280 102.7 1.1e-28 1
AE010299_4265 CDS_5398551-5395465 98.7 1.4e-27 1
AE010299_2284 CDS_2893050-2890873 96.9 4.5e-27 1
AE010299_2483 CDS_3181698-3179476 94.6 2e-26 1
AE010299_1906 CDS_2420127-2418628 94.2 2.6e-26 1
AE010299_1692 CDS_2089290-2087062 93.1 5.3e-26 1
AE010299_2481 CDS_3177757-3175577 92.8 6.5e-26 1
AE010299_3318 CDS_4210861-4208576 91.7 1.3e-25 1
AE010299_2233 CDS_2822401-2824119 89.0 7.9e-25 1
AE010299_3859 CDS_4861673-4860546 87.8 1.7e-24 1
AE010299_2196 CDS_2775244-2777907 87.6 1.9e-24 1
AE010299_3283 CDS_4157233-4161576 86.9 3e-24 1
AE010299_1116 CDS_1362234-1359685 80.8 1.7e-22 1
AE010299_1235 CDS_1517687-1513317 49.2 1.5e-13 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AE010299_1962 1/1 444 509 .. 1 87 [] 102.7 1.1e-28
AE010299_4265 1/1 487 555 .. 1 87 [] 98.7 1.4e-27
AE010299_2284 1/1 495 563 .. 1 87 [] 96.9 4.5e-27
AE010299_2483 1/1 490 558 .. 1 87 [] 94.6 2e-26
AE010299_1906 1/1 248 316 .. 1 87 [] 94.2 2.6e-26
AE010299_1692 1/1 499 567 .. 1 87 [] 93.1 5.3e-26
AE010299_2481 1/1 497 565 .. 1 87 [] 92.8 6.5e-26
AE010299_3318 1/1 523 591 .. 1 87 [] 91.7 1.3e-25
AE010299_2233 1/1 326 394 .. 1 87 [] 89.0 7.9e-25
AE010299_3859 1/1 150 218 .. 1 87 [] 87.8 1.7e-24
AE010299_2196 1/1 336 404 .. 1 87 [] 87.6 1.9e-24
AE010299_3283 1/1 1212 1280 .. 1 87 [] 86.9 3e-24
AE010299_1116 1/1 590 658 .. 1 87 [] 80.8 1.7e-22
AE010299_1235 1/1 1226 1294 .. 1 87 [] 49.2 1.5e-13

Alignments of top-scoring domains:
AE010299_1962: domain 1 of 1, from 444 to 509: score 102.7, E = 1.1e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak++flan+sHE+RTP++a++g++e+Lle t l++eq
AE010299_1 444 AKGDFLANMSHEIRTPMNAVLGMLEMLLE---------TSLTDEQ-- 479

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
reyl+ ++ +ae+ll++i+d+Ld+s+ie++
AE010299_1 480 ----------REYLQLAHASAESLLSIIDDVLDFSKIEQN 509

AE010299_4265: domain 1 of 1, from 487 to 555: score 98.7, E = 1.4e-27
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++I+g++++L e+++ +el+e+q
AE010299_4 487 TKSEFLANMSHELRTPLNSIIGFSDILIERVF------GELNEKQ-- 525

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+y++ i ++++ll Lind+Ldls+ eag
AE010299_4 526 ----------LKYVNNISGSGKHLLGLINDILDLSKVEAG 555

AE010299_2284: domain 1 of 1, from 495 to 563: score 96.9, E = 4.5e-27
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ksefl+n+sHELRTPL+a++g+a++L ee++ ++l+ +q
AE010299_2 495 SKSEFLSNMSHELRTPLNAVIGFADILNEEGF------GPLNKKQ-- 533

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++ i ++++ll+Lin++Ldls+ieag
AE010299_2 534 ----------KRFVGNISTSGKHLLKLINEILDLSKIEAG 563

AE010299_2483: domain 1 of 1, from 490 to 558: score 94.6, E = 2e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++I+g+++lL e+ + ++l+e+q
AE010299_2 490 TKSEFLANMSHELRTPLNSIIGFSDLLYEKIY------GDLNEKQ-- 528

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ i r++++ll+Lind+Ldls+ eag
AE010299_2 529 ----------LKAVGNISRSGKHLLNLINDILDLSKVEAG 558

AE010299_1906: domain 1 of 1, from 248 to 316: score 94.2, E = 2.6e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aksef+a++sHEL+TPL++I+g+++lLle++ +++lse q
AE010299_1 248 AKSEFIATVSHELKTPLNSIIGFSDLLLEDS------SGKLSERQ-- 286

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++y++ i ++++ll+ i+d+Ldls+ieag
AE010299_1 287 ----------ARYINNISISGKHLLQFIDDILDLSKIEAG 316

AE010299_1692: domain 1 of 1, from 499 to 567: score 93.1, E = 5.3e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++I+g+++lL e ++ +el+e+q
AE010299_1 499 TKSEFLANISHELRTPLNSIIGFSDLLCE------QIFGELNEKQ-- 537

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+y i +++++ll+Lind+Ldls+ eag
AE010299_1 538 ----------LRYAGNISKSGKHLLSLINDILDLSKVEAG 567

AE010299_2481: domain 1 of 1, from 497 to 565: score 92.8, E = 6.5e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks flan+sHELRTPL++I+g+++lL e+++ +el+ +q
AE010299_2 497 AKSAFLANMSHELRTPLNSIIGFSDLLYEKVY------GELNLKQ-- 535

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ i +++++ll+Lin++Ldls+ eag
AE010299_2 536 ----------TKAVGNISNSGKHLLNLINEILDLSKVEAG 565

AE010299_3318: domain 1 of 1, from 523 to 591: score 91.7, E = 1.3e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ksefl n+sHEL+TPL++I+g+++lL+e + ++l+e+q
AE010299_3 523 TKSEFLTNMSHELKTPLNSIIGFSDLLKE------EIAGPLNEKQ-- 561

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+y++ i ++++ ll++ind+Ldls++e+g
AE010299_3 562 ----------SRYVQFISSSGKNLLEIINDILDLSKAESG 591

AE010299_2233: domain 1 of 1, from 326 to 394: score 89.0, E = 7.9e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aksefla++sHELRTPL++I+g++++Ll+ + ++l+ +q
AE010299_2 326 AKSEFLASMSHELRTPLNSIIGFSDMLLT------QNFGPLNKKQ-- 364

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+y++ i ++++ll+Lin +Ldls+ eag
AE010299_2 365 ----------LRYVNNISVSGNHLLKLINGILDLSKVEAG 394

AE010299_3859: domain 1 of 1, from 150 to 218: score 87.8, E = 1.7e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ f+ n+sHELRTPL++++g+++lLle+++ ++l+ +q
AE010299_3 150 AKNSFIMNMSHELRTPLNSVIGFSDLLLEGAF------GPLNTKQ-- 188

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+y++ il +++ ll++in+lLd+sr+eag
AE010299_3 189 ----------SKYVNNILISGKNLLEIINNLLDISRLEAG 218

AE010299_2196: domain 1 of 1, from 336 to 404: score 87.6, E = 1.9e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+sefla++sHELRTPLtaI+g++el+l e+ +e +e
AE010299_2 336 AMSEFLATMSHELRTPLTAIIGFSELMLGEAT------GEFDELN-- 374

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++l i +++++ll+Lin + dlsrieag
AE010299_2 375 ----------RKFLGHISNSGKHLLSLINSVIDLSRIEAG 404

AE010299_3283: domain 1 of 1, from 1212 to 1280: score 86.9, E = 3e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k++flan+sHELRTPL++I+g++++L e+++ +el+ +q
AE010299_3 1212 TKNDFLANMSHELRTPLNSIIGFSDMLYEQAY------GELNRKQ-- 1250

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ i +++++ll+Lin +Ldls+iea+
AE010299_3 1251 ----------LRAIGNISSSGKHLLNLINGILDLSKIEAN 1280

AE010299_1116: domain 1 of 1, from 590 to 658: score 80.8, E = 1.7e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak f+ n+sHELRTPL+a++g+++lLl e ++l+e+q
AE010299_1 590 AKINFIVNMSHELRTPLNAVIGFSDLLLSETA------GPLNEKQ-- 628

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++y+e i +++ +ll+ ind+Ld+sr+e g
AE010299_1 629 ----------KRYTENISKSGSHLLDVINDVLDISRLELG 658

AE010299_1235: domain 1 of 1, from 1226 to 1294: score 49.2, E = 1.5e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+ sH+L PL I y++lL++++ +el+e
AE010299_1 1226 DLEQFAYVSSHDLQEPLRMIASYLQLLQRRYQ------GELDERA-- 1264

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+y+ + + a r+++LindlL++sr +
AE010299_1 1265 ----------DKYIYFAVDGASRMQSLINDLLEFSRVTTK 1294


Histogram of all scores:
score obs exp (one = represents 15 sequences)
----- --- ---
-15 1 0|=
-14 17 0|==
-13 97 3|*======
-12 344 103|======*================
-11 537 538|===================================*
-10 869 998|==========================================================*
-9 845 1031|========================================================= *
-8 685 771|============================================== *
-7 450 486|============================== *
-6 274 279|==================*
-5 184 153|==========*==
-4 91 82|=====*=
-3 53 43|==*=
-2 34 22|=*=
-1 19 11|*=
0 9 6|*
1 8 3|*
2 3 1|*
3 3 0|=
4 1 0|=
> 5 16 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 639.2460
P(chi-square) = 0

Total sequences searched: 4540

Whole sequence top hits:
tophits_s report:
Total hits: 14
Satisfying E cutoff: 14
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 14
Satisfying E cutoff: 14
Total memory: 26K


Acknowledgements:

This research is funded by:

Developed by: