Acidobacteria Actinobacteria Alphaproteobacteria
Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria
Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
Search:
264 projects found  

1 accessions found for Escherichia coli CFT073  

Data for AE014075  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AE014075.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AE014075_3270 CDS_3189875-3192631 100.1 6.5e-28 1
AE014075_0487 CDS_491955-493250 91.0 2.6e-25 1
AE014075_2831 CDS_2766762-2770355 81.6 1.2e-22 1
AE014075_1096 CDS_1089916-1088186 80.7 2e-22 1
AE014075_2690 CDS_2606729-2603880 80.6 2.3e-22 1
AE014075_3879 CDS_3786517-3784181 78.9 6.9e-22 1
AE014075_2691 CDS_2606884-2608722 77.9 1.3e-21 1
AE014075_3003 CDS_2954010-2952520 75.4 6.7e-21 1
AE014075_2535 CDS_2449462-2450865 70.4 1.7e-19 1
AE014075_3482 CDS_3414690-3413218 68.1 7.9e-19 1
AE014075_4760 CDS_4624633-4623260 66.6 2.1e-18 1
AE014075_5375 CDS_5226472-5227896 62.4 3.1e-17 1
AE014075_4858 CDS_4733127-4734503 61.5 5.8e-17 1
AE014075_0631 CDS_638391-636949 61.0 8e-17 1
AE014075_3679 CDS_3598892-3600241 60.7 1e-16 1
AE014075_4716 CDS_4581834-4580785 59.7 1.9e-16 1
AE014075_0753 CDS_765152-762465 59.6 2e-16 1
AE014075_4087 CDS_3962733-3961381 55.0 4e-15 1
AE014075_2321 CDS_2189790-2188432 51.1 5.1e-14 1
AE014075_5010 CDS_4891817-4890717 45.0 2.8e-12 1
AE014075_1939 CDS_1843577-1844878 42.4 1.5e-11 1
AE014075_5094 CDS_4956962-4958971 29.4 7.3e-08 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AE014075_3270 1/1 292 357 .. 1 87 [] 100.1 6.5e-28
AE014075_0487 1/1 203 269 .. 1 87 [] 91.0 2.6e-25
AE014075_2831 1/1 711 777 .. 1 87 [] 81.6 1.2e-22
AE014075_1096 1/1 109 174 .. 1 87 [] 80.7 2e-22
AE014075_2690 1/1 469 534 .. 1 87 [] 80.6 2.3e-22
AE014075_3879 1/1 282 347 .. 1 87 [] 78.9 6.9e-22
AE014075_2691 1/1 392 457 .. 1 87 [] 77.9 1.3e-21
AE014075_3003 1/1 270 338 .. 1 87 [] 75.4 6.7e-21
AE014075_2535 1/1 240 304 .. 1 87 [] 70.4 1.7e-19
AE014075_3482 1/1 268 336 .. 1 87 [] 68.1 7.9e-19
AE014075_4760 1/1 238 300 .. 1 87 [] 66.6 2.1e-18
AE014075_5375 1/1 255 320 .. 1 87 [] 62.4 3.1e-17
AE014075_4858 1/1 237 303 .. 1 87 [] 61.5 5.8e-17
AE014075_0631 1/1 261 327 .. 1 87 [] 61.0 8e-17
AE014075_3679 1/1 236 302 .. 1 87 [] 60.7 1e-16
AE014075_4716 1/1 129 186 .. 1 79 [. 59.7 1.9e-16
AE014075_0753 1/1 664 731 .. 1 87 [] 59.6 2e-16
AE014075_4087 1/1 233 293 .. 1 87 [] 55.0 4e-15
AE014075_2321 1/1 235 301 .. 1 87 [] 51.1 5.1e-14
AE014075_5010 1/1 145 205 .. 1 87 [] 45.0 2.8e-12
AE014075_1939 1/1 211 271 .. 1 87 [] 42.4 1.5e-11
AE014075_5094 1/1 448 516 .. 1 87 [] 29.4 7.3e-08

Alignments of top-scoring domains:
AE014075_3270: domain 1 of 1, from 292 to 357: score 100.1, E = 6.5e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ tel++ q
AE014075_3 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------TELTPTQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ti+r+a+ ll++ind+Ld+s++eag
AE014075_3 328 ----------RDHLNTIERSANNLLAIINDVLDFSKLEAG 357

AE014075_0487: domain 1 of 1, from 203 to 269: score 91.0, E = 2.6e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e++ e ++l r
AE014075_0 203 ARRNFFANVSHELRTPLTVLQGYLEMMDE---------QPLEGAVR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t++++++r++ L+ +lL+ls+iea
AE014075_0 240 ----------EKALHTMREQTQRMEGLVKQLLTLSKIEAA 269

AE014075_2831: domain 1 of 1, from 711 to 777: score 81.6, E = 1.2e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fla++sHE+RTP+++I+g++elL + ls eqr
AE014075_2 711 AKSQFLATMSHEIRTPISSIMGFLELLSG---------SGLSKEQR- 747

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+++ ++ +++ll Li ++Ld +ie+g
AE014075_2 748 ----------VEAISLAYATGQSLLGLIGEILDVDKIESG 777

AE014075_1096: domain 1 of 1, from 109 to 174: score 80.7, E = 2e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL +I+g+a+lL + ++ q
AE014075_1 109 AKSAFLAAMSHEIRTPLYGILGTAQLLAD---------NPALNAQ-- 144

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ i +++e+ll ++nd+Ld+s ieag
AE014075_1 145 ----------RDDLRAITDSGESLLTILNDILDYSAIEAG 174

AE014075_2690: domain 1 of 1, from 469 to 534: score 80.6, E = 2.3e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
AE014075_2 469 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPKGV-- 504

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
AE014075_2 505 ----------DRLVTAMNNSSSLLLKIISDILDFSKIESE 534

AE014075_3879: domain 1 of 1, from 282 to 347: score 78.9, E = 6.9e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ tel++eq
AE014075_3 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TELTAEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
AE014075_3 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

AE014075_2691: domain 1 of 1, from 392 to 457: score 77.9, E = 1.3e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++a+++HE R+PLtaIrgy+++L+ +++++ +
AE014075_2 392 TLGELMAGVAHEVRNPLTAIRGYVQILRQ---------QTRDPIH-- 427

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+eyl+++l+e++++++ i++lL++sr ++
AE014075_2 428 ----------QEYLSVVLKEIDSINKVIQQLLEFSRPRHS 457

AE014075_3003: domain 1 of 1, from 270 to 338: score 75.4, E = 6.7e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +fl++lsHEL+TPL+++r +elL +++ ++l++eq
AE014075_3 270 QRHQFLRHLSHELKTPLASMREGTELLADQV------VGPLTPEQ-- 308

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e +++++++++ l++Li++lLd+ r +a
AE014075_3 309 ----------KEVVSILDSSSRNLQKLIEQLLDYNRKQAD 338

AE014075_2535: domain 1 of 1, from 240 to 304: score 70.4, E = 1.7e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPL+++rg +e++++++ + ++e+
AE014075_2 240 MRRDFMADISHELRTPLAVLRGELEAIQDGV-------RKFTPET-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l +++ e+ l +L++dl +ls ++g
AE014075_2 278 -------------LASLQAEVGTLTKLVDDLHQLSMSDEG 304

AE014075_3482: domain 1 of 1, from 268 to 336: score 68.1, E = 7.9e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ef+an+sH+LRTPLt+++gy+e+L +++ + ls+e+
AE014075_3 268 QRREFIANISHDLRTPLTSLLGYLETLSMKS-------DSLSSED-- 305

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl t+lr+++ ++L +l +l+r+e+g
AE014075_3 306 ---------CHKYLTTALRQGHKVRHLSCQLFELARLEHG 336

AE014075_4760: domain 1 of 1, from 238 to 300: score 66.6, E = 2.1e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
AE014075_4 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RSGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr ++
AE014075_4 274 -------------LERIETEAQRLDSMINDLLVMSRNQQK 300

AE014075_5375: domain 1 of 1, from 255 to 320: score 62.4, E = 3.1e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l HEL+ PL+aIrg+ae+L+e ++ +e
AE014075_5 255 YIEQYVYALTHELKSPLAAIRGAAEILRE---------GPPPEVV-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ il + r+++L++ lL +r+e+
AE014075_5 291 ----------ARFTDNILTQNARMQALVETLLRQARLENR 320

AE014075_4858: domain 1 of 1, from 237 to 303: score 61.5, E = 5.8e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE+R+PL++I+g+a+ e +++++ e
AE014075_4 237 ALGHLAAGVAHEIRNPLSSIKGLAKYFAE--------RAPAGGEA-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++ +ea+rl+r +++lL+l + +
AE014075_4 274 ----------HQLAQVMAKEADRLNRVVSELLELVKPTHL 303

AE014075_0631: domain 1 of 1, from 261 to 327: score 61.0, E = 8e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s f a+++HE+RTP+t +++ +e++l + +s +++
AE014075_0 261 RQSNFSADIAHEIRTPITNLITQTEIALS---------QSRSQKEL- 297

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l + l+e+ r+ ++++d+L l++++++
AE014075_0 298 ----------EDVLYSNLEELTRMAKMVSDMLFLAQADNN 327

AE014075_3679: domain 1 of 1, from 236 to 302: score 60.7, E = 1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PLta++ +e+++ ++ +++ r
AE014075_3 236 RERRFTSDAAHELRSPLTALKVQTEVAQL---------SDDDPQAR- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l +++ ++r rL+++lL+lsr+++
AE014075_3 273 ----------KKALLQLHSGIDRATRLVDQLLTLSRLDSL 302

AE014075_4716: domain 1 of 1, from 129 to 186: score 59.7, E = 1.9e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
AE014075_4 129 AARDLVRGLAHEIKNPLGGLRGAAQLLSK----------ALPDPSL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
AE014075_4 165 ----------LEYTKVIIEQADRLRNLVDRLL 186

AE014075_0753: domain 1 of 1, from 664 to 731: score 59.6, E = 2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l + ++++
AE014075_0 664 IRNALLAALSHDLRTPLTVLFGQAEILTLDL-------ASEGSPH-- 701

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + i++ + rL+n+lLd++ri++g
AE014075_0 702 ----------ARQASEIRQHVLNTTRLVNNLLDMARIQSG 731

AE014075_4087: domain 1 of 1, from 233 to 293: score 55.0, E = 4e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e ++
AE014075_4 233 DRTLLMAGVSHDLRTPLTRIRLATEMMSE---------QD------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
AE014075_4 264 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 293

AE014075_2321: domain 1 of 1, from 235 to 301: score 51.1, E = 5.1e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f+ +l+HELRTP++a++g ++ l + +s +
AE014075_2 235 RLSQFADDLAHELRTPINALLGQNQVTLS---------QIRSIAE-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y++ + ++e+e ++rL +++L l+r++ +
AE014075_2 271 ---------YQKTIAGNIEELENISRLTENILFLARADKN 301

AE014075_5010: domain 1 of 1, from 145 to 205: score 45.0, E = 2.8e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+++r+++elL + t+
AE014075_5 145 NERLFTADVAHELRTPLAGVRLHLELLAK---------TH------- 175

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + ++++ + +++lL+l+r+++
AE014075_5 176 ----------HIDVAPLVARLDQMMESVSQLLQLARAGQS 205

AE014075_1939: domain 1 of 1, from 211 to 271: score 42.4, E = 1.5e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ + ls+ +
AE014075_1 211 SKKQLIDGIAHELRTPLVRLRYRLEMSDN-----------LSAAE-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
AE014075_1 245 -------------SQALNRDISQLEALIEELLTYARLDRP 271

AE014075_5094: domain 1 of 1, from 448 to 516: score 29.4, E = 7.3e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l+HE+++PL+a+++y+ ++++ a+++++ e+
AE014075_5 448 VVGQTMTTLAHEINQPLNALSMYLFTARR------AIEQTQKEQA-- 486

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+l +++ + r++++i+ l++++r +
AE014075_5 487 ----------SMMLGKAEGVISRIDAIIRSLRQFTRRAEL 516


Histogram of all scores:
score obs exp (one = represents 17 sequences)
----- --- ---
-16 1 0|=
-15 5 0|=
-14 56 0|====
-13 138 4|*========
-12 353 122|=======*=============
-11 625 637|=====================================*
-10 935 1182|======================================================= *
-9 958 1221|========================================================= *
-8 826 914|================================================= *
-7 604 576|=================================*==
-6 379 331|===================*===
-5 215 181|==========*==
-4 103 97|=====*=
-3 56 51|==*=
-2 33 26|=*
-1 32 14|*=
0 17 7|*
1 7 3|*
2 7 1|*
3 2 1|*
4 1 0|=
> 5 26 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 599.5790
P(chi-square) = 0

Total sequences searched: 5379

Whole sequence top hits:
tophits_s report:
Total hits: 22
Satisfying E cutoff: 22
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 22
Satisfying E cutoff: 22
Total memory: 29K


Acknowledgements:

This research is funded by:

Developed by: