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Classification of phyla is from NCBI page
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2 accessions found for Brucella suis 1330  

Data for AE014291  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AE014291.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AE014291_0591 CDS_611617-609266 90.3 1.5e-25 1
AE014291_1558 CDS_1549933-1553040 89.7 2.4e-25 1
AE014291_0289 CDS_310223-311539 85.6 3.4e-24 1
AE014291_2029 CDS_2013889-2015694 73.9 7.1e-21 1
AE014291_2037 CDS_2019333-2021912 69.6 1.1e-19 1
AE014291_0554 CDS_569937-571766 63.3 6.9e-18 1
AE014291_1085 CDS_1097075-1095972 55.3 1.3e-15 1
AE014291_0588 CDS_602362-603765 48.8 9.2e-14 1
AE014291_0307 CDS_330657-327133 45.0 1.1e-12 1
AE014291_1083 CDS_1094409-1092085 42.4 5.8e-12 1
AE014291_0129 CDS_148850-150142 40.1 2.6e-11 1
AE014291_1007 CDS_1003944-1006781 39.5 4e-11 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AE014291_0591 1/1 543 612 .. 1 87 [] 90.3 1.5e-25
AE014291_1558 1/1 795 864 .. 1 87 [] 89.7 2.4e-25
AE014291_0289 1/1 200 267 .. 1 87 [] 85.6 3.4e-24
AE014291_2029 1/1 364 429 .. 1 87 [] 73.9 7.1e-21
AE014291_2037 1/1 627 695 .. 1 87 [] 69.6 1.1e-19
AE014291_0554 1/1 328 397 .. 1 87 [] 63.3 6.9e-18
AE014291_1085 1/1 122 186 .. 1 87 [] 55.3 1.3e-15
AE014291_0588 1/1 240 306 .. 1 87 [] 48.8 9.2e-14
AE014291_0307 1/1 801 866 .. 1 87 [] 45.0 1.1e-12
AE014291_1083 1/1 525 596 .. 1 87 [] 42.4 5.8e-12
AE014291_0129 1/1 209 275 .. 1 87 [] 40.1 2.6e-11
AE014291_1007 1/1 567 633 .. 1 87 [] 39.5 4e-11

Alignments of top-scoring domains:
AE014291_0591: domain 1 of 1, from 543 to 612: score 90.3, E = 1.5e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
akseflan+sHELRTPL+aI+g++e+++++ + ++l+++
AE014291_0 543 AKSEFLANMSHELRTPLNAIIGFSEMIQAGTF------GPLGSDR-- 581

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ey++ i+ +++ ll+ ind+Ld+s+ieag
AE014291_0 582 ---------YEEYINDIHTSGNFLLNVINDILDMSKIEAG 612

AE014291_1558: domain 1 of 1, from 795 to 864: score 89.7, E = 2.4e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k+efla +sHE+RTPL+aI+g++el+ + + ++ + +
AE014291_1 795 QKTEFLARISHEIRTPLNAIIGFSELMAD------EKFGPIGNDR-- 833

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr+yl+ i r++++ l+L+ndlLd+s+ieag
AE014291_1 834 ---------YRDYLRDINRSGNHVLALVNDLLDISKIEAG 864

AE014291_0289: domain 1 of 1, from 200 to 267: score 85.6, E = 3.4e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f+an+sHELRTPL+++rg++e+L+ +++++ ++
AE014291_0 200 MRSDFIANASHELRTPLASLRGFIETLQG---------PARNDAAAR 237

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l++++++aer++rLi+dlL lsr+e
AE014291_0 238 ----------DRFLDIMQKQAERMSRLIDDLLSLSRLEMR 267

AE014291_2029: domain 1 of 1, from 364 to 429: score 73.9, E = 7.1e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + f+a++sHEL++PLt++r ++e+L ++++e r
AE014291_2 364 AIESFAADVSHELKNPLTSLRSAVETLPL----------AKTDESR- 399

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l++i+++++rl+rLi d+ d sr++a+
AE014291_2 400 ----------KRLLDVIQHDVRRLDRLITDISDVSRLDAE 429

AE014291_2037: domain 1 of 1, from 627 to 695: score 69.6, E = 1.1e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k++f+ ++s ELR PLt I+g++elL++ + + l+e q
AE014291_2 627 IKNDFVQHVSYELRSPLTNIIGFTELLQT------PAFGSLNERQ-- 665

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
eyl+ i ++ ll ++nd+Ldl+ +ag
AE014291_2 666 ----------LEYLDHISTSSSVLLTIVNDILDLATVDAG 695

AE014291_0554: domain 1 of 1, from 328 to 397: score 63.3, E = 6.9e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+++la++sHELRTPL++I+g++++L + ++l ++ +
AE014291_0 328 GKGRLLATVSHELRTPLNSIIGFSDMLTH------EIGGKLASDRQ- 367

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
rey i++++++ll+L+n +Ld sr+e+g
AE014291_0 368 ----------REYAGLIHQSGHYLLELVNAVLDNSRLETG 397

AE014291_1085: domain 1 of 1, from 122 to 186: score 55.3, E = 1.3e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + ++++l+HE+++PL++Irg+a+lL+ s+e+
AE014291_1 122 SVTGLASMLAHEIKNPLSGIRGAAQLLEQ----------VVSDED-- 156

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r + + i +e++r+ +L++++ +s +
AE014291_1 157 ----------RALARLITEETDRIVSLVDRMEVFSDERPI 186

AE014291_0588: domain 1 of 1, from 240 to 306: score 48.8, E = 9.2e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + n++H+L+TPLt +r ae +l +e+ e++
AE014291_0 240 GLKQVSDNIAHDLKTPLTRLRNRAEEALG---------GEKVEPE-- 275

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr +le i+ e+++l r n +L +sr+eag
AE014291_0 276 ---------YRAALEDIIGESDQLIRTFNAILMISRLEAG 306

AE014291_0307: domain 1 of 1, from 801 to 866: score 45.0, E = 1.1e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k++fla++ H++ +PL+a r+y+ +L e +l+ ++
AE014291_0 801 GKTRFLAAAGHDILQPLNAARLYSTALAE----------KLGRSET- 836

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+ + i++++e ++++ +Ld+sr+++g
AE014291_0 837 ----------SEFARNIDSSLEAVEAILGMVLDISRLDTG 866

AE014291_1083: domain 1 of 1, from 525 to 596: score 42.4, E = 5.8e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + ++ ++HE+++PLt I++ ae +++++ ++ + + e
AE014291_1 525 AWADVARRIAHEIKNPLTPIQLSAERIRRRY----GKVITEDREV-- 565

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + ++ti+r++ + r+++++ ++r+ +
AE014291_1 566 ---------FDQCTDTIIRQVGDIGRMVDEFSAFARMPKP 596

AE014291_0129: domain 1 of 1, from 209 to 275: score 40.1, E = 2.6e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HEL TPL++I + ++ +++ +++++
AE014291_0 209 ALDGLAAAAAHELGTPLATIALVVKEMQR--------AHTKDPGL-- 245

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e + ++++++r+++++++l ls +++
AE014291_0 246 ----------EEDIALLHSQTQRCREILQRLTSLSSEGEE 275

AE014291_1007: domain 1 of 1, from 567 to 633: score 39.5, E = 4e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++ +++H++++ LtaI++ ++lLl++ + +s++
AE014291_1 567 AVGQLAGGIAHDFNNVLTAIIMSSDLLLTN--------HRASDPS-- 603

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ i++ a+r +L+++lL +sr ++
AE014291_1 604 ----------FPDIMNIKQNANRAASLVRQLLAFSRRQTL 633


Histogram of all scores:
score obs exp (one = represents 7 sequences)
----- --- ---
-15 3 0|=
-14 18 0|===
-13 51 1|*=======
-12 147 48|======*==============
-11 257 251|===================================*=
-10 349 466|================================================== *
-9 406 482|==========================================================*
-8 333 360|================================================ *
-7 240 227|================================*==
-6 133 130|==================*
-5 79 71|==========*=
-4 44 38|=====*=
-3 21 20|==*
-2 12 10|=*
-1 7 5|*
0 5 2|*
1 1 1|*
2 0 0|
3 1 0|=
> 4 16 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 246.7189
P(chi-square) = 0

Total sequences searched: 2123

Whole sequence top hits:
tophits_s report:
Total hits: 12
Satisfying E cutoff: 12
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 12
Satisfying E cutoff: 12
Total memory: 25K


Acknowledgements:

This research is funded by:

Developed by: