Acidobacteria Actinobacteria Alphaproteobacteria
Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria
Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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264 projects found  

1 accessions found for Salmonella enterica subsp. enterica serovar Typhi str. Ty2  

Data for AE014613  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AE014613.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AE014613_2678 CDS_2947953-2950709 100.2 5.2e-28 1
AE014613_2311 CDS_2538052-2536757 86.6 3.7e-24 1
AE014613_1178 CDS_1334065-1331303 82.3 5.8e-23 1
AE014613_0565 CDS_674170-677016 80.6 1.8e-22 1
AE014613_3036 CDS_3332845-3330509 78.9 5.4e-22 1
AE014613_3443 CDS_3807761-3805026 72.8 2.8e-20 1
AE014613_0283 CDS_333203-334588 69.6 2.3e-19 1
AE014613_3321 CDS_3661344-3662717 67.0 1.2e-18 1
AE014613_0701 CDS_822836-821433 63.5 1.3e-17 1
AE014613_3229 CDS_3549757-3548360 62.5 2.4e-17 1
AE014613_2038 CDS_2235518-2238202 61.1 6.2e-17 1
AE014613_3371 CDS_3715665-3716714 60.3 1e-16 1
AE014613_4314 CDS_4779459-4780883 59.6 1.6e-16 1
AE014613_1711 CDS_1886713-1888077 57.5 6.4e-16 1
AE014613_2898 CDS_3184452-3185801 55.9 1.8e-15 1
AE014613_3730 CDS_4155629-4156981 54.9 3.5e-15 1
AE014613_3917 CDS_4363486-4362407 47.7 3.9e-13 1
AE014613_1253 CDS_1401701-1400397 47.4 4.5e-13 1
AE014613_2503 CDS_2772694-2771279 36.6 5.2e-10 1
AE014613_0439 CDS_534271-536277 35.3 1.3e-09 1
AE014613_1172 CDS_1325817-1327595 31.5 1.5e-08 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AE014613_2678 1/1 292 357 .. 1 87 [] 100.2 5.2e-28
AE014613_2311 1/1 203 269 .. 1 87 [] 86.6 3.7e-24
AE014613_1178 1/1 395 460 .. 1 87 [] 82.3 5.8e-23
AE014613_0565 1/1 469 534 .. 1 87 [] 80.6 1.8e-22
AE014613_3036 1/1 282 347 .. 1 87 [] 78.9 5.4e-22
AE014613_3443 1/1 444 509 .. 1 87 [] 72.8 2.8e-20
AE014613_0283 1/1 234 302 .. 1 87 [] 69.6 2.3e-19
AE014613_3321 1/1 238 300 .. 1 87 [] 67.0 1.2e-18
AE014613_0701 1/1 240 304 .. 1 87 [] 63.5 1.3e-17
AE014613_3229 1/1 246 312 .. 1 87 [] 62.5 2.4e-17
AE014613_2038 1/1 663 730 .. 1 87 [] 61.1 6.2e-17
AE014613_3371 1/1 129 186 .. 1 79 [. 60.3 1e-16
AE014613_4314 1/1 255 320 .. 1 87 [] 59.6 1.6e-16
AE014613_1711 1/1 236 302 .. 1 87 [] 57.5 6.4e-16
AE014613_2898 1/1 236 302 .. 1 87 [] 55.9 1.8e-15
AE014613_3730 1/1 233 293 .. 1 87 [] 54.9 3.5e-15
AE014613_3917 1/1 145 205 .. 1 87 [] 47.7 3.9e-13
AE014613_1253 1/1 212 272 .. 1 87 [] 47.4 4.5e-13
AE014613_2503 1/1 246 311 .. 1 87 [] 36.6 5.2e-10
AE014613_0439 1/1 447 515 .. 1 87 [] 35.3 1.3e-09
AE014613_1172 1/1 357 426 .. 1 87 [] 31.5 1.5e-08

Alignments of top-scoring domains:
AE014613_2678: domain 1 of 1, from 292 to 357: score 100.2, E = 5.2e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ tel++ q
AE014613_2 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------TELNPTQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ti+r+a+ ll++ind+Ld+s++eag
AE014613_2 328 ----------RDHLNTIERSANNLLAIINDVLDFSKLEAG 357

AE014613_2311: domain 1 of 1, from 203 to 269: score 86.6, E = 3.7e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e+++e ++l +r
AE014613_2 203 ARRNFFANVSHELRTPLTVLQGYLEMMQE---------QALEGATR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t+++++ r++ L+ +lL+ls+ie
AE014613_2 240 ----------EKALHTMREQTYRMEGLVKQLLTLSKIEVA 269

AE014613_1178: domain 1 of 1, from 395 to 460: score 82.3, E = 5.8e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks l +sHELRTP+++++g++elL++ t+l+ eq
AE014613_1 395 RKSIHLTVISHELRTPMNGVLGAIELLQT---------TPLNIEQ-- 430

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + +t+++++ +ll++in+lLd+srie+g
AE014613_1 431 ----------QGLADTARNCTLSLLAIINNLLDFSRIESG 460

AE014613_0565: domain 1 of 1, from 469 to 534: score 80.6, E = 1.8e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
AE014613_0 469 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPKGV-- 504

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
AE014613_0 505 ----------DRLVTAMNNSSSLLLKIISDILDFSKIESE 534

AE014613_3036: domain 1 of 1, from 282 to 347: score 78.9, E = 5.4e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ t+l++eq
AE014613_3 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TDLTAEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
AE014613_3 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

AE014613_3443: domain 1 of 1, from 444 to 509: score 72.8, E = 2.8e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL +I+g+++lL + +l +
AE014613_3 444 AKSTFLAAMSHEIRTPLYGILGTVQLLAD---------KPLMANY-- 479

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ i +++e+ll+++nd+Ld+s ie g
AE014613_3 480 ----------RDDLQAINDSGESLLAILNDILDYSAIEVG 509

AE014613_0283: domain 1 of 1, from 234 to 302: score 69.6, E = 2.3e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +fl++lsHEL+TPL+++r +elL +++ ++l++eq
AE014613_0 234 QRHQFLRHLSHELKTPLASMREGTELLADQV------VGPLTPEQ-- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e +++++++++ l++Li++lLd+ r
AE014613_0 273 ----------KEVVDILDDSSRNLQKLIEQLLDYNRKLVD 302

AE014613_3321: domain 1 of 1, from 238 to 300: score 67.0, E = 1.2e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
AE014613_3 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RGGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr ++
AE014613_3 274 -------------LERIETEAQRLDSMINDLLVMSRNQQK 300

AE014613_0701: domain 1 of 1, from 240 to 304: score 63.5, E = 1.3e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPL+++rg +e++++++ ++e
AE014613_0 240 MRRDFMADISHELRTPLAVLRGELEAIQDGV-------RQFTPES-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ e+ l +L++dl +ls ++g
AE014613_0 278 -------------VTSLQAEVGTLTKLVDDLHQLSLSDEG 304

AE014613_3229: domain 1 of 1, from 246 to 312: score 62.5, E = 2.4e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE+R+PL++I+g+a+ e +t+++ e
AE014613_3 246 AMGHLAAGVAHEIRNPLSSIKGLAKYFAE--------RTPAGGES-- 282

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+ +++ +ea+rl+r +++lL+l + +
AE014613_3 283 ----------HELAQVMAKEADRLNRVVSELLELVKPAHL 312

AE014613_2038: domain 1 of 1, from 663 to 730: score 61.1, E = 6.2e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l + +++++
AE014613_2 663 IRNALLAALSHDLRTPLTVLFGQAEILTLDL-------ASAGSPH-- 700

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + i++ + rL+n+lLd++ri++g
AE014613_2 701 ----------ARQASEIRQHILNTTRLVNNLLDMARIQSG 730

AE014613_3371: domain 1 of 1, from 129 to 186: score 60.3, E = 1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
AE014613_3 129 AARDLVRGLAHEIKNPLGGLRGAAQLLSK----------ALPDPAL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
AE014613_3 165 ----------TEYTKVIIEQADRLRNLVDRLL 186

AE014613_4314: domain 1 of 1, from 255 to 320: score 59.6, E = 1.6e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l HEL+ PL+aIrg+ae+L+e ++ +
AE014613_4 255 DIEQYVYALTHELKSPLAAIRGAAEILRE---------GPPADVV-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++e il + r+++L++ lL +r+e+
AE014613_4 291 ----------TRFTENILAQNTRMQALVETLLRQARLENR 320

AE014613_1711: domain 1 of 1, from 236 to 302: score 57.5, E = 6.4e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ +l+HELRTP++ ++g +++l +e+s+e+
AE014613_1 236 RLNQFADDLAHELRTPVNILLGKNQVMLS---------QERSAEE-- 271

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+++l ++e+e l+rL +++L l+r+e++
AE014613_1 272 ---------YQQALVDNIEELEGLSRLTENILFLARAEHQ 302

AE014613_2898: domain 1 of 1, from 236 to 302: score 55.9, E = 1.8e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PL+a++ +e+++ + ++ r
AE014613_2 236 RERRFTSDAAHELRSPLAALKVQTEVAQL---------SGDDPLSR- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l ++ ++r rL+++lL+lsr+++
AE014613_2 273 ----------DKALTQLHAGIDRATRLVDQLLTLSRLDSL 302

AE014613_3730: domain 1 of 1, from 233 to 293: score 54.9, E = 3.5e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e e+
AE014613_3 233 DRTLLMAGVSHDLRTPLTRIRLATEMMGE--------------ED-- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
AE014613_3 264 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 293

AE014613_3917: domain 1 of 1, from 145 to 205: score 47.7, E = 3.9e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+++r+++elL + t+
AE014613_3 145 NERLFTADVAHELRTPLSGVRLHLELLSK---------TH------- 175

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++ ++++ + +++lL+l+r ++
AE014613_3 176 ----------NVDVAPLIARLDQMMDSVSQLLQLARVGQS 205

AE014613_1253: domain 1 of 1, from 212 to 272: score 47.4, E = 4.5e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ ++ l++++
AE014613_1 212 SKKQLIDGIAHELRTPLVRLRYRLEMSEN-----------LTPPE-- 245

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
AE014613_1 246 -------------SQALNRDIGQLEALIEELLTYARLDRP 272

AE014613_2503: domain 1 of 1, from 246 to 311: score 36.6, E = 5.2e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f a++sH+L+TPL+++++ a ++l+ + + +
AE014613_2 246 RQERFSADASHQLKTPLAVLKTQAAVALA----------SQHPHH-- 280

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e l+ + +++ +L ++lL+ls +
AE014613_2 281 ---------WYESLQAMSVTLDSTIQLTERLLQLSAVKHK 311

AE014613_0439: domain 1 of 1, from 447 to 515: score 35.3, E = 1.3e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l+HE+++PL+a+++y+ ++ + a+++ +s +
AE014613_0 447 VVGQTMTTLAHEINQPLNALSMYLFTAGR------AIEQGQSGQA-- 485

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r l +++ ++r++++i+ l++++r +
AE014613_0 486 ----------RNTLTKAEGLINRIDAIIRSLRQFTRRAEL 515

AE014613_1172: domain 1 of 1, from 357 to 426: score 31.5, E = 1.5e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++++ +HEL++PL+aIr ya+ +l +l +++e++ l
AE014613_1 357 VLGEMTSGFAHELNQPLSAIRHYAQGCLIRL-------RAADEQHPL 396

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+le i+++a+r + +++l+ +g
AE014613_1 397 ----------LPALEQIDQQAQRGADTLRNLRHWVSQAQG 426


Histogram of all scores:
score obs exp (one = represents 14 sequences)
----- --- ---
-16 1 0|=
-15 4 0|=
-14 25 0|==
-13 76 3|*=====
-12 221 98|======*=========
-11 479 512|=================================== *
-10 740 950|===================================================== *
-9 815 981|==========================================================*
-8 709 735|=================================================== *
-7 510 463|=================================*===
-6 303 266|==================*===
-5 206 146|==========*====
-4 90 78|=====*=
-3 36 41|==*
-2 33 21|=*=
-1 24 11|*=
0 15 5|*=
1 5 3|*
2 6 1|*
3 2 0|=
4 0 0|
> 5 23 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 299.7645
P(chi-square) = 0

Total sequences searched: 4323

Whole sequence top hits:
tophits_s report:
Total hits: 21
Satisfying E cutoff: 21
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 21
Satisfying E cutoff: 21
Total memory: 29K


Acknowledgements:

This research is funded by:

Developed by: