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Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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264 projects found  

2 accessions found for Vibrio vulnificus CMCP6  

Data for AE016795  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AE016795.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AE016795_2905 CDS_3199600-3197444 95.2 9.1e-27 1
AE016795_2020 CDS_2180851-2183172 94.8 1.2e-26 1
AE016795_1452 CDS_1546173-1543387 94.1 1.8e-26 1
AE016795_2466 CDS_2708240-2710528 86.6 2.5e-24 1
AE016795_0444 CDS_467093-465885 82.5 3.7e-23 1
AE016795_1546 CDS_1655060-1651671 81.2 8.6e-23 1
AE016795_2427 CDS_2659419-2661143 77.8 7.5e-22 1
AE016795_2098 CDS_2279419-2281134 75.1 4.4e-21 1
AE016795_0522 CDS_553759-551417 73.9 1e-20 1
AE016795_2971 CDS_3274613-3278272 71.6 4.5e-20 1
AE016795_1153 CDS_1221795-1225226 59.6 1.1e-16 1
AE016795_0849 CDS_901411-902421 59.2 1.4e-16 1
AE016795_1787 CDS_1922559-1923593 56.0 1.2e-15 1
AE016795_1860 CDS_2005957-2004350 55.3 1.8e-15 1
AE016795_0815 CDS_867292-865994 50.7 3.6e-14 2
AE016795_1164 CDS_1239356-1237968 50.1 5.5e-14 1
AE016795_0118 CDS_112163-110907 49.6 7.5e-14 1
AE016795_0024 CDS_27482-29269 46.5 5.7e-13 1
AE016795_2385 CDS_2615123-2617105 42.4 8e-12 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AE016795_2905 1/1 265 331 .. 1 87 [] 95.2 9.1e-27
AE016795_2020 1/1 320 385 .. 1 87 [] 94.8 1.2e-26
AE016795_1452 1/1 290 355 .. 1 87 [] 94.1 1.8e-26
AE016795_2466 1/1 239 304 .. 1 87 [] 86.6 2.5e-24
AE016795_0444 1/1 175 242 .. 1 87 [] 82.5 3.7e-23
AE016795_1546 1/1 459 527 .. 1 87 [] 81.2 8.6e-23
AE016795_2427 1/1 214 279 .. 1 87 [] 77.8 7.5e-22
AE016795_2098 1/1 207 272 .. 1 87 [] 75.1 4.4e-21
AE016795_0522 1/1 282 347 .. 1 87 [] 73.9 1e-20
AE016795_2971 1/1 635 700 .. 1 87 [] 71.6 4.5e-20
AE016795_1153 1/1 788 853 .. 1 87 [] 59.6 1.1e-16
AE016795_0849 1/1 117 182 .. 1 87 [] 59.2 1.4e-16
AE016795_1787 1/1 122 188 .. 1 87 [] 56.0 1.2e-15
AE016795_1860 1/1 305 371 .. 1 87 [] 55.3 1.8e-15
AE016795_1164 1/1 244 306 .. 1 87 [] 50.1 5.5e-14
AE016795_0118 1/1 220 286 .. 1 87 [] 49.6 7.5e-14
AE016795_0815 2/2 222 282 .. 1 87 [] 47.3 3.3e-13
AE016795_0024 1/1 372 440 .. 1 87 [] 46.5 5.7e-13
AE016795_2385 1/1 428 495 .. 1 87 [] 42.4 8e-12

Alignments of top-scoring domains:
AE016795_2905: domain 1 of 1, from 265 to 331: score 95.2, E = 9.1e-27
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks flan+sHELRTPL+a++gy++l++ d+ l++++
AE016795_2 265 AKSIFLANMSHELRTPLNAVLGYTQLMKC--------DQRLTAKH-- 301

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+eyle+i r++e+ll+Lind+Ld+s+i+ag
AE016795_2 302 ----------HEYLEIINRSGEHLLSLINDVLDMSKIDAG 331

AE016795_2020: domain 1 of 1, from 320 to 385: score 94.8, E = 1.2e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ fla+lsHE+RTP+++++g+a++Ll+ t+l+eeq
AE016795_2 320 AKTAFLATLSHEIRTPMNGVLGTAQILLK---------TPLNEEQ-- 355

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+t++++++++ L+n++Ld+s+ie+g
AE016795_2 356 ----------RKHLKTLYDSGDHMMTLLNEILDYSKIEQG 385

AE016795_1452: domain 1 of 1, from 290 to 355: score 94.1, E = 1.8e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ +l+ t l+ q
AE016795_1 290 VKSEFLANMSHELRTPLNGVIGFTRQMLK---------TQLTNSQ-- 325

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+yl+ti+++a+ ll++ind+Ld+s++eag
AE016795_1 326 ----------TDYLQTIEKSANNLLNIINDILDFSKLEAG 355

AE016795_2466: domain 1 of 1, from 239 to 304: score 86.6, E = 2.5e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks+fla++sHE+RTP+++++g++ +L e t+l+ q
AE016795_2 239 SKSRFLASMSHEIRTPMNGVLGLLGILGE---------TKLDNHQ-- 274

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++t+++++e ll++ind+Ld+sr+ea+
AE016795_2 275 ----------QNLVHTAKESGELLLSIINDILDFSRMEAN 304

AE016795_0444: domain 1 of 1, from 175 to 242: score 82.5, E = 3.7e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f+an+sHELRTP+t+++gy+e+ ++ +++
AE016795_0 175 MRRNFFANVSHELRTPMTVLQGYLEMTED---------PDMLVGP-- 210

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ ++ +++ ++++r+++L+n+lL+ls+iea
AE016795_0 211 --------MWGKAHRVMTEQLNRMNSLVNQLLTLSKIEAS 242

AE016795_1546: domain 1 of 1, from 459 to 527: score 81.2, E = 8.6e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+efla+ sHELRTPL++++g ae+L +++ ++l++ q
AE016795_1 459 LKDEFLATTSHELRTPLHGMIGIAETLISGAN------GPLPSNQ-- 497

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r l++i+++++rl L++dlLd+ +++ g
AE016795_1 498 ----------RYQLDIIIKSGQRLATLVDDLLDYHKMRYG 527

AE016795_2427: domain 1 of 1, from 214 to 279: score 77.8, E = 7.5e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aksefla++sHELRTPL++++g++++L+ +++s+ ++
AE016795_2 214 AKSEFLAMMSHELRTPLNSVLGMLDVLKQ---------SDMSAGHI- 250

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+l+ ++++a ll++i+d+Ldls+ie+g
AE016795_2 251 -----------NLLSHMESSAGLLLAIISDILDLSKIESG 279

AE016795_2098: domain 1 of 1, from 207 to 272: score 75.1, E = 4.4e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ef+a++ HELRTPL++++g aelL + t l++eq
AE016795_2 207 ATKEFVAMINHELRTPLNGVLGSAELLGN---------TYLNDEQ-- 242

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ yl+ +++ +e l+ +indlLd+s++ ag
AE016795_2 243 ----------QLYLRNLRQGGELLRVIINDLLDFSKMNAG 272

AE016795_0522: domain 1 of 1, from 282 to 347: score 73.9, E = 1e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ t l++eq
AE016795_0 282 DKTTFISTISHELRTPLNGIVGLSRMLLD---------TRLTDEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+y +ti +a l ++ nd+ d+ + +
AE016795_0 318 ----------RKYMQTINVSAITLGNIFNDIIDMDKFDRR 347

AE016795_2971: domain 1 of 1, from 635 to 700: score 71.6, E = 4.5e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ fla++sHELRTP+++++g++e+ + + e
AE016795_2 635 ARQMFLATMSHELRTPIAGMMGLLEMVTS---------KTEDKES-- 670

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+l+ i +a+ l+ L+nd+Ld+s++e++
AE016795_2 671 ----------LFLLDQISASAKNLNFLVNDILDFSKLESN 700

AE016795_1153: domain 1 of 1, from 788 to 853: score 59.6, E = 1.1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks+fla++sH+L +PL+a r++a+ L e ++++e
AE016795_1 788 SKSRFLAAVSHDLMQPLNAARLFASSLSE---------VAKDDES-- 823

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++ + i++++ ++Li dlLd+sr+e+g
AE016795_1 824 ----------RKLAHHIESALGAAEDLIGDLLDISRLESG 853

AE016795_0849: domain 1 of 1, from 117 to 182: score 59.2, E = 1.4e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++l+HE+++PL ++rg+a+lL++ l+++ +
AE016795_0 117 AAKLLVRGLAHEIKNPLGGLRGAAQLLEK----------MLPDPSL- 152

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
ey+++i+++a+rl++L+++lL + +
AE016795_0 153 ----------TEYTQIIIEQADRLRALVDRLLGPQKPGKK 182

AE016795_1787: domain 1 of 1, from 122 to 188: score 56.0, E = 1.2e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++++a+l+H+ RTPL++ ++ya+ L + ++l+ +r
AE016795_1 122 SLGRMVASLAHQVRTPLSSAMLYASNLSA---------PNLPNTTR- 158

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++ + ++ l++++nd+L +++ + +
AE016795_1 159 ----------ERFQSKLMDRLQDLEKQVNDMLLFAKGGDN 188

AE016795_1860: domain 1 of 1, from 305 to 371: score 55.3, E = 1.8e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++e++ +++H+LRTPL +r+++e+L++ ++ s+ q+
AE016795_1 305 RQRELTNAVAHDLRTPLYRLRFAIEMLED---------PHTSDAQK- 341

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++y + ++ +++ l++Lin+ L lsr
AE016795_1 342 ----------EKYQRALHTSIDDLDHLINQNLLLSRYNRI 371

AE016795_1164: domain 1 of 1, from 244 to 306: score 50.1, E = 5.5e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++l+++sHELR PLt +r++ l+ + + +
AE016795_1 244 GQQRLLSDISHELRSPLTRLRMANALATR---------KQGESNE-- 279

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l++i+ ea+rl+++i++lL+lsr++ +
AE016795_1 280 -------------LQRIDTEAQRLEQMISELLELSRMQMN 306

AE016795_0118: domain 1 of 1, from 220 to 286: score 49.6, E = 7.5e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +ef + +sHELRTP+ +I+g a++L + e ++ +
AE016795_0 220 REQEFSRFASHELRTPIMVIQGSADILSR---------VEGQPQVA- 256

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++++++++++ + L + +L l + e +
AE016795_0 257 ----------QKAIRRLHQAGQEMKVLTETFLLLGKSEIE 286

AE016795_0815: domain 2 of 2, from 222 to 282: score 47.3, E = 3.3e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++a++sH+LRTPLt Ir+++e++ e+
AE016795_0 222 DRALLMAGISHDLRTPLTRIRLATEMMSP--------------ED-- 252

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e i++++e ++++i++++d+ + +
AE016795_0 253 ----------SYLAEGIISDTEECNEIISQFMDYLKPVNT 282

AE016795_0024: domain 1 of 1, from 372 to 440: score 46.5, E = 5.7e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ a++sHEL++PL+aIr +a+ + +l+ e+ +
AE016795_0 372 VIGQMSASISHELNNPLAAIRSFADNGRLFLE------KEKYPRV-- 410

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e l++i +er+ ++ ++l+ ++r ag
AE016795_0 411 ----------DENLSRISALTERMAKISQQLRSFARKSAG 440

AE016795_2385: domain 1 of 1, from 428 to 495: score 42.4, E = 8e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++e++a+++HE+++P ++I+g++el++ el +e +
AE016795_2 428 ALGELTAGIAHEINNPTAVILGNVELIRFEL-------GEDAARV-- 465

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e +et+ +++r++++ + lL++sr +
AE016795_2 466 ----------EEEIETVMAQIDRIRNITRSLLQYSRQGGV 495


Histogram of all scores:
score obs exp (one = represents 10 sequences)
----- --- ---
-14 7 0|=
-13 43 2|*====
-12 162 67|======*==========
-11 298 352|============================== *
-10 514 653|==================================================== *
-9 554 675|======================================================== *
-8 465 505|=============================================== *
-7 372 318|===============================*======
-6 216 183|==================*===
-5 124 100|=========*===
-4 71 53|=====*==
-3 55 28|==*===
-2 28 14|=*=
-1 17 7|*=
0 10 4|*
1 8 2|*
2 3 1|*
3 1 0|=
4 1 0|=
5 1 0|=
6 0 0|
7 0 0|
> 8 23 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 266.3364
P(chi-square) = 0

Total sequences searched: 2973

Whole sequence top hits:
tophits_s report:
Total hits: 19
Satisfying E cutoff: 19
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 19
Satisfying E cutoff: 19
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: