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Classification of phyla is from NCBI page
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2 accessions found for Vibrio vulnificus CMCP6  

Data for AE016796  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AE016796.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AE016796_1099 CDS_1280202-1282130 104.7 9.8e-30 1
AE016796_0912 CDS_1057765-1053803 103.5 2.1e-29 1
AE016796_0073 CDS_76060-79278 95.2 4.8e-27 1
AE016796_0711 CDS_815033-812586 92.3 3.2e-26 1
AE016796_0118 CDS_124906-127818 90.7 9.1e-26 1
AE016796_0703 CDS_806680-804107 79.0 1.8e-22 1
AE016796_0353 CDS_393710-397822 77.7 4.3e-22 1
AE016796_0130 CDS_143341-146940 74.5 3.4e-21 1
AE016796_0866 CDS_1007341-1009491 74.4 3.8e-21 1
AE016796_1396 CDS_1645543-1641890 71.0 3.5e-20 1
AE016796_0924 CDS_1072230-1073582 64.9 1.8e-18 1
AE016796_1190 CDS_1402946-1401606 57.5 2.2e-16 1
AE016796_1314 CDS_1562569-1561289 53.5 3e-15 1
AE016796_0726 CDS_830265-828865 47.1 2e-13 1
AE016796_0294 CDS_331066-329651 28.9 2.8e-08 1
AE016796_0201 CDS_234788-237151 28.1 4.9e-08 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AE016796_1099 1/1 240 305 .. 1 87 [] 104.7 9.8e-30
AE016796_0912 1/1 598 663 .. 1 87 [] 103.5 2.1e-29
AE016796_0073 1/1 299 364 .. 1 87 [] 95.2 4.8e-27
AE016796_0711 1/1 307 372 .. 1 87 [] 92.3 3.2e-26
AE016796_0118 1/1 470 535 .. 1 87 [] 90.7 9.1e-26
AE016796_0703 1/1 483 548 .. 1 87 [] 79.0 1.8e-22
AE016796_0353 1/1 668 736 .. 1 87 [] 77.7 4.3e-22
AE016796_0130 1/1 666 731 .. 1 87 [] 74.5 3.4e-21
AE016796_0866 1/1 234 299 .. 1 87 [] 74.4 3.8e-21
AE016796_1396 1/1 673 738 .. 1 87 [] 71.0 3.5e-20
AE016796_0924 1/1 224 290 .. 1 87 [] 64.9 1.8e-18
AE016796_1190 1/1 228 293 .. 1 87 [] 57.5 2.2e-16
AE016796_1314 1/1 210 275 .. 1 87 [] 53.5 3e-15
AE016796_0726 1/1 222 286 .. 1 87 [] 47.1 2e-13
AE016796_0294 1/1 263 330 .. 1 87 [] 28.9 2.8e-08
AE016796_0201 1/1 565 633 .. 1 87 [] 28.1 4.9e-08

Alignments of top-scoring domains:
AE016796_1099: domain 1 of 1, from 240 to 305: score 104.7, E = 9.8e-30
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ksefla++sHE+RTP+++I+g a+lL+e els+eq
AE016796_1 240 KKSEFLATMSHEIRTPMNGIIGVASLLKE---------MELSSEQ-- 275

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++y+e i +++e+ll++ind+Ld+s+ieag
AE016796_1 276 ----------KQYVEMINHSSESLLDIINDILDFSKIEAG 305

AE016796_0912: domain 1 of 1, from 598 to 663: score 103.5, E = 2.1e-29
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak++flan+sHE+RTP++aI+g+a+l+l+ tel++ q
AE016796_0 598 AKGDFLANMSHEIRTPMNAILGMAHLALN---------TELDPSQ-- 633

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+yl +i ++a+ ll +ind+Ld+s+ieag
AE016796_0 634 ----------RKYLTRINESAKNLLGIINDILDFSKIEAG 663

AE016796_0073: domain 1 of 1, from 299 to 364: score 95.2, E = 4.8e-27
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ks flan+sHE+RTP++aI+g+++l+l+ t+l+++q
AE016796_0 299 VKSMFLANMSHEIRTPMNAIIGMSHLALK---------TDLTPKQ-- 334

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++y+++i+++a ll +ind+Ld+s+ieag
AE016796_0 335 ----------HDYVSKIHSSATLLLGIINDILDFSKIEAG 364

AE016796_0711: domain 1 of 1, from 307 to 372: score 92.3, E = 3.2e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks flan+sHE+RTPL++I+g++e+L +els++q
AE016796_0 307 AKSVFLANMSHEIRTPLNGIIGMTEILSQ---------SELSSQQ-- 342

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+l i+ ++++ll L+nd+Ldls+ie+g
AE016796_0 343 ----------KEILGDIDTSSQSLLILLNDILDLSKIESG 372

AE016796_0118: domain 1 of 1, from 470 to 535: score 90.7, E = 9.1e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTP+++++g+a lL + + l++ q
AE016796_0 470 AKSAFLATMSHEIRTPMNGVLGTARLLMD---------SGLNPLQ-- 505

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++y ++i r+++ ll+++nd+Ld+s+ieag
AE016796_0 506 ----------KRYADIINRSGKNLLAILNDVLDYSKIEAG 535

AE016796_0703: domain 1 of 1, from 483 to 548: score 79.0, E = 1.8e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +fla +sHE+RTPL++I+g a+lL++ + ++e
AE016796_0 483 TRADFLAKMSHEIRTPLNGILGIAQLLKR---------SVNDAEN-- 518

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++++ +++e+ll+ +nd+Ld+s+ie+g
AE016796_0 519 ----------LKQVDVLCNSGEHLLAVLNDILDFSKIEQG 548

AE016796_0353: domain 1 of 1, from 668 to 736: score 77.7, E = 4.3e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++I+ +++l + +d++l+++q+
AE016796_0 668 YKSEFLANMSHELRTPLNSILILSQLFAN------NKDGNLTAKQI- 707

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e + i +++ ll+Lin++Ldls+ eag
AE016796_0 708 -----------ESAKAINSSGSDLLSLINEILDLSKVEAG 736

AE016796_0130: domain 1 of 1, from 666 to 731: score 74.5, E = 3.4e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++fla +sHELRTP++a++g+ e+L ++e
AE016796_0 666 ARNQFLAVVSHELRTPIAAMLGLMEILSH---------RLSNSES-- 701

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+ ++r+aerl+ +nd+Ld+s+iea
AE016796_0 702 ----------QQLLDNAIRSAERLSLHVNDILDFSKIEAS 731

AE016796_0866: domain 1 of 1, from 234 to 299: score 74.4, E = 3.8e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ks+flan+sHE RTPL+aI+g++++ + ++ ++se+
AE016796_0 234 TKSKFLANISHEVRTPLNAIIGLSDT--D-------HYLNASEQI-- 269

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
rey++ i+r++++ll+L nd+Ld+s+i++g
AE016796_0 270 ----------REYIDLIHRSGKHLLALMNDILDISKIDSG 299

AE016796_1396: domain 1 of 1, from 673 to 738: score 71.0, E = 3.5e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++fla++sHELRTPL+a g+++l + + se +
AE016796_1 673 ARERFLATMSHELRTPLAATYGLLDLVAT---------HSTSERD-- 708

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e++ ++++++++l+ L++++Ld+s++eag
AE016796_1 709 ----------KELVLRAKQSLNHLNLLVDEVLDYSKLEAG 738

AE016796_0924: domain 1 of 1, from 224 to 290: score 64.9, E = 1.8e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++sef ++++HELRTP+ +++ ++++l+ ++se++
AE016796_0 224 RLSEFSSDIAHELRTPIGNMMTQTQVMLA---------KPRSEQE-- 259

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr++le+ +e+ rl + i+d+L l++ e++
AE016796_0 260 ---------YRDILESNAEELSRLTKTISDMLYLAKSEHN 290

AE016796_1190: domain 1 of 1, from 228 to 293: score 57.5, E = 2.2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +f+++++HEL+TPLt +r++ae +l+ +++q+
AE016796_1 228 REKRFTRTAAHELKTPLTILRLNAENALA----------SENPQQL- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l+ il+ ++r +rLi +lL+l++ e+
AE016796_1 264 ----------SHDLNNILKGIDRTDRLIHQLLTLAKVENA 293

AE016796_1314: domain 1 of 1, from 210 to 275: score 53.5, E = 3e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++ +++HELRTP+ ++ a+lL + ++l+e+q
AE016796_1 210 SNKVLTNAVAHELRTPIFRLQWQADLLAD---------SPLNEKQ-- 245

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ ++++ ++++ ++++++++L ++++e +
AE016796_1 246 ----------QKSVSSMVEDIDEMEAMVEEMLYYAKMERP 275

AE016796_0726: domain 1 of 1, from 222 to 286: score 47.1, E = 2e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + f ++ HE+RTPL+ I+++++l ++ + ++eq
AE016796_0 222 QSQIFSQAIPHEIRTPLSRIQMASDLVRR----------KVPAEQ-- 256

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ i++ +e +++L d+ +lsr+ a
AE016796_0 257 ----------QRLFDDIDEYIEDINELTTDVIQLSRLNAL 286

AE016796_0294: domain 1 of 1, from 263 to 330: score 28.9, E = 2.8e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ l l HELRTP++++++++e ++e+ ++l+e
AE016796_0 263 SRMLVLQILTHELRTPIASLSLTVEGFRREF-------EHLPETV-- 300

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++++ ++++rl++L + d+ + +++
AE016796_0 301 ----------YDEFRRLCEDTRRLRQLAEASKDYLQSDNQ 330

AE016796_0201: domain 1 of 1, from 565 to 633: score 28.1, E = 4.9e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l+HEL++PL+a+++y+ + + +++++eq+
AE016796_0 565 VVGQAMTSLAHELNQPLNAMSTYLYSANLFN-------QKADSEQV- 603

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ l i++ er+++++n l+ +++ g
AE016796_0 604 ----------ATSLTHIESLKERMSKIVNGLRHFAKKSDG 633


Histogram of all scores:
score obs exp (one = represents 5 sequences)
----- --- ---
-15 1 0|=
-14 6 0|==
-13 22 1|*====
-12 79 35|======*=========
-11 135 185|=========================== *
-10 258 344|==================================================== *
-9 295 355|==========================================================*
-8 241 266|================================================= *
-7 186 167|=================================*====
-6 131 96|===================*=======
-5 81 52|==========*======
-4 45 28|=====*===
-3 21 14|==*==
-2 18 7|=*==
-1 10 4|*=
0 7 2|*=
1 5 1|*
2 3 0|=
> 3 21 -|=====


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 154.7496
P(chi-square) = 3.922e-28

Total sequences searched: 1565

Whole sequence top hits:
tophits_s report:
Total hits: 16
Satisfying E cutoff: 16
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 16
Satisfying E cutoff: 16
Total memory: 27K


Acknowledgements:

This research is funded by:

Developed by: