Acidobacteria Actinobacteria Alphaproteobacteria
Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria
Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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19 projects found  

2 accessions found for Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130  

Data for AE016823  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AE016823.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AE016823_1661 CDS_2078425-2075927 124.7 4.5e-35 2
AE016823_3100 CDS_3909961-3907493 99.0 8.5e-28 1
AE016823_1394 CDS_1762057-1759004 94.1 2.2e-26 1
AE016823_0536 CDS_677904-675814 93.0 4.4e-26 1
AE016823_2994 CDS_3766557-3768233 92.3 6.7e-26 1
AE016823_3177 CDS_4008668-4010059 86.2 3.7e-24 1
AE016823_1487 CDS_1890866-1888671 81.5 7.7e-23 1
AE016823_1994 CDS_2496220-2493296 76.0 2.8e-21 1
AE016823_1387 CDS_1751396-1752517 66.9 1e-18 1
AE016823_2311 CDS_2883898-2885286 61.0 4.9e-17 1
AE016823_1992 CDS_2492595-2491480 60.3 7.9e-17 1
AE016823_2170 CDS_2702119-2700653 57.5 5e-16 1
AE016823_1660 CDS_2075888-2074740 54.5 3.4e-15 1
AE016823_2031 CDS_2535790-2536923 50.9 3.7e-14 1
AE016823_0967 CDS_1207792-1210404 49.6 8.8e-14 1
AE016823_3020 CDS_3808106-3805797 43.4 4.9e-12 1
AE016823_1507 CDS_1909889-1911679 43.0 6.3e-12 1
AE016823_1844 CDS_2293497-2292172 42.7 7.7e-12 1
AE016823_2021 CDS_2525511-2526965 37.6 2.2e-10 1
AE016823_1170 CDS_1478223-1480895 37.3 2.5e-10 1
AE016823_3019 CDS_3805751-3804228 37.0 3.2e-10 1
AE016823_1172 CDS_1481329-1482834 28.7 7e-08 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AE016823_3100 1/1 436 501 .. 1 87 [] 99.0 8.5e-28
AE016823_1394 1/1 504 569 .. 1 87 [] 94.1 2.2e-26
AE016823_0536 1/1 323 388 .. 1 87 [] 93.0 4.4e-26
AE016823_2994 1/1 185 250 .. 1 87 [] 92.3 6.7e-26
AE016823_3177 1/1 232 300 .. 1 87 [] 86.2 3.7e-24
AE016823_1661 1/2 208 274 .. 1 87 [] 83.1 2.7e-23
AE016823_1487 1/1 342 407 .. 1 87 [] 81.5 7.7e-23
AE016823_1994 1/1 548 616 .. 1 87 [] 76.0 2.8e-21
AE016823_1387 1/1 148 214 .. 1 87 [] 66.9 1e-18
AE016823_2311 1/1 238 306 .. 1 87 [] 61.0 4.9e-17
AE016823_1992 1/1 152 220 .. 1 87 [] 60.3 7.9e-17
AE016823_2170 1/1 274 340 .. 1 87 [] 57.5 5e-16
AE016823_1660 1/1 151 217 .. 1 87 [] 54.5 3.4e-15
AE016823_2031 1/1 152 220 .. 1 87 [] 50.9 3.7e-14
AE016823_0967 1/1 648 716 .. 1 87 [] 49.6 8.8e-14
AE016823_3020 1/1 549 616 .. 1 87 [] 43.4 4.9e-12
AE016823_1507 1/1 365 437 .. 1 87 [] 43.0 6.3e-12
AE016823_1844 1/1 223 286 .. 1 87 [] 42.7 7.7e-12
AE016823_1661 2/2 606 674 .. 1 87 [] 41.6 1.6e-11
AE016823_2021 1/1 264 332 .. 1 87 [] 37.6 2.2e-10
AE016823_1170 1/1 665 732 .. 1 87 [] 37.3 2.5e-10
AE016823_3019 1/1 288 354 .. 1 87 [] 37.0 3.2e-10
AE016823_1172 1/1 153 219 .. 1 87 [] 28.7 7e-08

Alignments of top-scoring domains:
AE016823_3100: domain 1 of 1, from 436 to 501: score 99.0, E = 8.5e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ks flan+sHE+RTP+++++g+++lL + t+l++eq
AE016823_3 436 VKSNFLANMSHEIRTPMNGVLGMVQLLGT---------TKLNDEQ-- 471

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ey+e++ +a++ll++ind+Ld+s+ieag
AE016823_3 472 ----------KEYVEVLSVSAKSLLQIINDILDFSKIEAG 501

AE016823_1394: domain 1 of 1, from 504 to 569: score 94.1, E = 2.2e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak++fla++sHE+RTPL++++g+++lL+ t l+ eq
AE016823_1 504 AKTDFLAMMSHEIRTPLNGVIGTVSLLEG---------TFLNTEQ-- 539

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+eyl++i+++++ ll L+nd+Ldlsrie+g
AE016823_1 540 ----------KEYLDIIKSSGQNLLILLNDILDLSRIESG 569

AE016823_0536: domain 1 of 1, from 323 to 388: score 93.0, E = 4.4e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ f++n+sHE+RTP+t+I+g +elLl+ t+l+++q
AE016823_0 323 AKTVFISNISHEIRTPMTGILGITELLLN---------TPLNPDQ-- 358

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ le i+r+++ ll+++n lLd+s++++g
AE016823_0 359 ----------KDSLELIQRSGDKLLKIVNHLLDFSKADTG 388

AE016823_2994: domain 1 of 1, from 185 to 250: score 92.3, E = 6.7e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks f+an+sHE+RTP+++I+g + lL e tel eq
AE016823_2 185 SKSLFFANMSHEIRTPVHGILGVSGLLSE---------TELQQEQ-- 220

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ey++ti+r+++ ll+L+nd+Ld+s++e+
AE016823_2 221 ----------KEYVDTIQRSGKLLLNLLNDILDFSKLESF 250

AE016823_3177: domain 1 of 1, from 232 to 300: score 86.2, E = 3.7e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+ n+sHEL+TP+t+I+gy+e+Ll+ + ls+e +
AE016823_3 232 IREQFVQNASHELKTPITSIKGYTETLLD--------RLRLSPESHE 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+ i r ++r+ r+++d+L+++rie++
AE016823_3 271 ----------KRFLDAISRNTDRMVRIVEDMLTITRIENQ 300

AE016823_1661: domain 1 of 2, from 208 to 274: score 83.1, E = 2.7e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ks+f+an+sHELRTPLt I+g + +Ll+ d+ ++ q
AE016823_1 208 LKSQFFANVSHELRTPLTLILGPTRALLK--------DQGITSTQ-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r +leti+r + ll+ +ndlLdls++++g
AE016823_1 245 ----------RTFLETIERNSYTLLKHVNDLLDLSKLDSG 274

AE016823_1487: domain 1 of 1, from 342 to 407: score 81.5, E = 7.7e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
akseflan+sHELRTPL++I+g++ l++ +e e +
AE016823_1 342 AKSEFLANMSHELRTPLNSIIGFSRLMQF---------PEGMERE-- 377

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+yl+ i +++ +ll++ind+Ldlsriea
AE016823_1 378 ----------NRYLDLIFHSGVHLLNIINDILDLSRIEAD 407

AE016823_1994: domain 1 of 1, from 548 to 616: score 76.0, E = 2.8e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++ +++ L + ++ +lse+q
AE016823_1 548 YKSEFLANMSHELRTPLNSLLILSKDLAD------NKRKNLSEDQ-- 586

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e ++i+++++ ll Lind+Ldls+ie+g
AE016823_1 587 ----------VESANIIYKSGHDLLVLINDVLDLSKIESG 616

AE016823_1387: domain 1 of 1, from 148 to 214: score 66.9, E = 1e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + + a+++HE+++PL +++ yae++ + + + +
AE016823_1 148 AIGTLSAGVAHEINNPLMGVINYAEMMVN---------GIENGNPL- 184

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+y +ilre++r+++++ d+L+++rie +
AE016823_1 185 ----------RKYAGIILREGNRISEIVKDMLTFTRIEKE 214

AE016823_2311: domain 1 of 1, from 238 to 306: score 61.0, E = 4.9e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ f ++sH+LR P+ +I+g++++Lle + ++e r
AE016823_2 238 DLEAFSYSVSHDLRSPIRGILGFSKILLE----------DHGAELRE 274

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ r+++++i+r +e + +Li+dlL++sr++
AE016823_2 275 DS--------RRIVNIIIRNSENMGKLIDDLLEYSRLGRR 306

AE016823_1992: domain 1 of 1, from 152 to 220: score 60.3, E = 7.9e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f+ ++sH+L+ PL aIrgy+++L+e+++ ++ +ee
AE016823_1 152 ELDAFTYSVSHDLKAPLRAIRGYTKILKEDYE------EKFDEEG-- 190

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l i++ + +++Li+ lL ls+++
AE016823_1 191 ----------KRVLGLIIDNSLKMSSLIDSLLLLSKLGKK 220

AE016823_2170: domain 1 of 1, from 274 to 340: score 57.5, E = 5e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++++a+l+HE+++PL +I+ y +++++ ++ ++ ++
AE016823_2 274 SIQKLAAGLAHEINNPLMGIINYGHVIQN---------HKGGDAET- 310

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ y + i++++er+ ++i++l +s+ + +
AE016823_2 311 ----------KNYARLIIEQGERIAAIIRNLVLFSKKDPE 340

AE016823_1660: domain 1 of 1, from 151 to 217: score 54.5, E = 3.4e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++ +++HE+++PL aI+ ya ++ + +e ++e++
AE016823_1 151 AMGVMAGTMAHEINNPLIAISEYAAMIAK---------GEVDSEKA- 187

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ ++i++e+ r++ + +lL +sr + g
AE016823_1 188 ----------KQLASKIRDESARISTIMKNLLRFSRDDKG 217

AE016823_2031: domain 1 of 1, from 152 to 220: score 50.9, E = 3.7e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f+++++HEL++PLt+++++++ Ll++l t +++
AE016823_2 152 SLGIFISGVAHELNNPLTGMSLTLQSLLNNL-------TSIDPDF-- 189

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+r+ l+ +++++ r ++ d+ +++ +
AE016823_2 190 ---------FRKRLDMMKEDLTRAAMIVTDIISFAKPDRL 220

AE016823_0967: domain 1 of 1, from 648 to 716: score 49.6, E = 8.8e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + +lsHEL+TPL++Irg++ +Lle +e
AE016823_0 648 LYTIIFNSLSHELKTPLSSIRGAVTALLE---------PEIENSR-- 683

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+R e+l+ i +++ l+ L+ +lLd+sr e+g
AE016823_0 684 -EAR------VELLNEINESSMILNLLLGNLLDMSRYESG 716

AE016823_3020: domain 1 of 1, from 549 to 616: score 43.4, E = 4.9e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +e++a+++HE ++PL a ++y+e L e +e ++ +r
AE016823_3 549 SIGELAAGIAHEVNNPLQASLLYLEELIE--------TEESDPAER- 586

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ ++i+ ++ r+++Li lLdl r a
AE016823_3 587 ----------LKIYKRIEAASVRIRDLIKSLLDLGRTVAR 616

AE016823_1507: domain 1 of 1, from 365 to 437: score 43.0, E = 6.3e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a e + ++HE+++PLt I++ ae +++++ + eq
AE016823_1 365 AWKEVAQRMAHEIKNPLTPIQLSAERIRRKM-------NSENKEQ-- 402

peLRledpeyreyl....etilreaerllrLindlLdlsrieag<-*
+ e+++++++ti+++++ l++L+n++ d++r+ a+
AE016823_1 403 ---------FYEIVssgtDTIIKQVRVLEHLVNEFSDFARMPAP 437

AE016823_1844: domain 1 of 1, from 223 to 286: score 42.7, E = 7.7e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + ++ HE++ PL+++++ +el+ e +++ +
AE016823_1 223 YVENYVQSMTHEIKSPLSSLLASSELIIE------------NPDRL- 256

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ i+ e++r++ +++ lL+ls +e++
AE016823_1 257 ----------ESLVSNIQLEGRRIQTILEKLLELSSLENQ 286

AE016823_1661: domain 2 of 2, from 606 to 674: score 41.6, E = 1.6e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ f ++sH+LR P+ +I g+++++le++ ++++++e
AE016823_1 606 DMESFSYSVSHDLRAPILVIEGFLQIILEDF------SEKMDPEA-- 644

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ l+++++ + ++++Li+dlL + +
AE016823_1 645 ----------LRSLKIVHKNVVYMNHLIQDLLSFHKVSKI 674

AE016823_2021: domain 1 of 1, from 264 to 332: score 37.6, E = 2.2e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ +sH+L PL +++ y+++L+e++ + ++
AE016823_2 264 ELEQFAFLASHDLQEPLRTVSNYIQVLEEDYG------NTFDSNA-- 302

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+yl+ti+++++r++ L+ lL ++ri+
AE016823_2 303 ----------TRYLKTIDQATKRMSVLVKALLMYARIGRD 332

AE016823_1170: domain 1 of 1, from 665 to 732: score 37.3, E = 2.5e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+ +sH+L PL I+++ + Ll+ + ++l++e
AE016823_1 665 DLEDFAFIASHDLQEPLRKIMAFGDRLLK-------KNSNLDSES-- 702

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+yl++++++a rl++Li+ lL +sri +
AE016823_1 703 ----------MDYLQRMYSSACRLSNLIEGLLSYSRIKSK 732

AE016823_3019: domain 1 of 1, from 288 to 354: score 37.0, E = 3.2e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+s +++++ HE+++ LtaI+g++e+++ ++++++ r
AE016823_3 288 FLSILASSIGHEINNSLTAIQGHIEIAKL---------PDATDPIR- 324

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++++ +++ l L n+lL+l + +++
AE016823_3 325 ----------QKAIQITWSQLVKLKTLTNNLLQLGKPGEN 354

AE016823_1172: domain 1 of 1, from 153 to 219: score 28.7, E = 7e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
s+f +++H++++ L+ I +++++L++ ++ +++
AE016823_1 153 IISQFSGGVAHDFNNILNIIVANLDILEM---------KCKDQPEV- 189

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++++++ r + lL +sr ++
AE016823_1 190 ----------LNRIQSAQNAVLRGAEVNKKLLNFSRKQSL 219


Histogram of all scores:
score obs exp (one = represents 11 sequences)
----- --- ---
-14 21 0|==
-13 60 2|*=====
-12 194 77|======*===========
-11 454 402|====================================*=====
-10 608 746|======================================================== *
-9 635 770|==========================================================*
-8 541 577|================================================== *
-7 346 363|================================*
-6 204 209|==================*
-5 134 114|==========*==
-4 67 61|=====*=
-3 48 32|==*==
-2 18 17|=*
-1 19 8|*=
0 9 4|*
1 4 2|*
2 1 1|*
3 0 0|
4 1 0|=
> 5 30 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 256.8563
P(chi-square) = 0

Total sequences searched: 3394

Whole sequence top hits:
tophits_s report:
Total hits: 22
Satisfying E cutoff: 22
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 23
Satisfying E cutoff: 23
Total memory: 30K


Acknowledgements:

This research is funded by:

Developed by: