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Classification of phyla is from NCBI page
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2 accessions found for Coxiella burnetii RSA 493  

Data for AE016828  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AE016828.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AE016828_1033 CDS_1030126-1028075 94.2 1.1e-26 1
AE016828_0352 CDS_331619-330861 86.4 1.9e-24 1
AE016828_0611 CDS_581614-583269 76.4 1.3e-21 1
AE016828_1692 CDS_1693082-1691109 55.9 8.2e-16 1
AE016828_1173 CDS_1177685-1179121 55.2 1.3e-15 1
AE016828_1931 CDS_1911986-1910709 45.4 7.9e-13 1
AE016828_0757 CDS_734759-737185 41.4 1.1e-11 2

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AE016828_1033 1/1 305 370 .. 1 87 [] 94.2 1.1e-26
AE016828_0352 1/1 27 94 .. 1 87 [] 86.4 1.9e-24
AE016828_0611 1/1 178 243 .. 1 87 [] 76.4 1.3e-21
AE016828_1692 1/1 140 205 .. 1 87 [] 55.9 8.2e-16
AE016828_1173 1/1 253 318 .. 1 87 [] 55.2 1.3e-15
AE016828_1931 1/1 217 275 .. 1 87 [] 45.4 7.9e-13
AE016828_0757 1/2 269 293 .. 1 25 [. 35.6 4.7e-10

Alignments of top-scoring domains:
AE016828_1033: domain 1 of 1, from 305 to 370: score 94.2, E = 1.1e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ks+fla++sHELRTPL+aI+g++++L++ ++ls+eq
AE016828_1 305 TKSDFLAMMSHELRTPLNAILGMSQILKT---------HNLSDEQ-- 340

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++i ++++ ll+L+ndlLd++++eag
AE016828_1 341 ----------QGQIDVISQAGQNLLALLNDLLDFAKLEAG 370

AE016828_0352: domain 1 of 1, from 27 to 94: score 86.4, E = 1.9e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+s+f+an+sHELRTPLt+Irgy+e+Ll+ + ++++
AE016828_0 27 IRSDFVANVSHELRTPLTVIRGYLETLLK--------KEVRDSKS-- 63

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+++++ +++ + r++ +i+dlL lsr+e+
AE016828_0 64 ---------YQKIFQQMYQHSARMETIIDDLLLLSRLESD 94

AE016828_0611: domain 1 of 1, from 178 to 243: score 76.4, E = 1.3e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aksef+an+sH+LRTP+++I+g a++ + +e + +q
AE016828_0 178 AKSEFIANISHDLRTPINGILGIAQIFNM---------HEHTKKQ-- 213

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ + +a+ ll L++d+Ld++r+e g
AE016828_0 214 ----------EPLINDLSASANLLLGLVEDILDFARLEVG 243

AE016828_1692: domain 1 of 1, from 140 to 205: score 55.9, E = 8.2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+ H+LRTPLt+I++ ae L + +++ee+
AE016828_1 140 VKSEFLANMGHDLRTPLTGIILIAEYLWK----------KQTEEKD- 175

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + ++ ++++ll+ in++L+++ eag
AE016828_1 176 ----------KQLSKDLILAGKQLLHFINEVLEITNVEAG 205

AE016828_1173: domain 1 of 1, from 253 to 318: score 55.2, E = 1.3e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +f+a+++HELRTPL+a+ ++++++l+ ++++e+r
AE016828_1 253 REKRFTADAAHELRTPLAALNTHTQVALR----------AKTPEER- 288

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+l ++l ++r + +++lL+l r+ +
AE016828_1 289 ----------KEALLKVLAGVNRGTHVVQQLLTLNRMVPE 318

AE016828_1931: domain 1 of 1, from 217 to 275: score 45.4, E = 7.9e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++la++sH+LRTP+t +++ a+ L +
AE016828_1 217 NRTQMLAAISHDLRTPITRMKLRAQFLDN------------------ 245

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + ++++ ++ +in+ L ++r +
AE016828_1 246 ----------STTRNALVKDLNEMEVMINETLSFARDDFA 275

AE016828_0757: domain 1 of 2, from 269 to 293: score 35.6, E = 4.7e-10
*->akseflanlsHELRTPLtaIrgyae<-*
aksef+an+sH++RTP+++++g+++
AE016828_0 269 AKSEFIANMSHDIRTPIAGMLGMLQ 293


Histogram of all scores:
score obs exp (one = represents 7 sequences)
----- --- ---
-15 2 0|=
-14 36 0|======
-13 71 1|*==========
-12 147 46|======*==============
-11 228 238|=================================*
-10 347 443|================================================== *
-9 368 457|===================================================== *
-8 288 342|========================================== *
-7 214 216|==============================*
-6 118 124|=================*
-5 72 68|=========*=
-4 61 36|=====*===
-3 21 19|==*
-2 17 10|=*=
-1 6 5|*
0 6 2|*
1 2 1|*
2 3 0|=
3 1 0|=
> 4 8 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 290.7999
P(chi-square) = 0

Total sequences searched: 2016

Whole sequence top hits:
tophits_s report:
Total hits: 7
Satisfying E cutoff: 7
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 7
Satisfying E cutoff: 7
Total memory: 23K


Acknowledgements:

This research is funded by:

Developed by: