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Thermotogae
Classification of phyla is from NCBI page
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106 projects found  

1 accessions found for Mycobacterium avium subsp. paratuberculosis K-10  

Data for AE016958  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AE016958.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AE016958_1001 CDS_1045068-1043530 86.0 5.2e-24 1
AE016958_0260 CDS_279272-280762 83.4 2.8e-23 1
AE016958_3359 CDS_3732865-3731171 73.9 1.4e-20 1
AE016958_3982 CDS_4440671-4441900 72.3 4e-20 1
AE016958_0592 CDS_618028-619464 71.1 9.1e-20 1
AE016958_0996 CDS_1038458-1035882 63.3 1.5e-17 1
AE016958_0917 CDS_949137-950672 61.4 4.9e-17 1
AE016958_1222 CDS_1279708-1281150 58.0 4.5e-16 1
AE016958_1101 CDS_1154491-1155894 55.4 2.4e-15 1
AE016958_0153 CDS_156382-157710 54.5 4.5e-15 1
AE016958_3390 CDS_3766970-3765375 48.0 3.1e-13 1
AE016958_0833 CDS_851892-850537 47.1 5.5e-13 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AE016958_1001 1/1 277 344 .. 1 87 [] 86.0 5.2e-24
AE016958_0260 1/1 269 335 .. 1 87 [] 83.4 2.8e-23
AE016958_3359 1/1 294 361 .. 1 87 [] 73.9 1.4e-20
AE016958_3982 1/1 156 222 .. 1 87 [] 72.3 4e-20
AE016958_0592 1/1 249 313 .. 1 87 [] 71.1 9.1e-20
AE016958_0996 1/1 628 696 .. 1 87 [] 63.3 1.5e-17
AE016958_0917 1/1 232 304 .. 1 87 [] 61.4 4.9e-17
AE016958_1222 1/1 257 325 .. 1 87 [] 58.0 4.5e-16
AE016958_1101 1/1 245 310 .. 1 87 [] 55.4 2.4e-15
AE016958_0153 1/1 222 288 .. 1 87 [] 54.5 4.5e-15
AE016958_3390 1/1 290 358 .. 1 87 [] 48.0 3.1e-13
AE016958_0833 1/1 229 295 .. 1 87 [] 47.1 5.5e-13

Alignments of top-scoring domains:
AE016958_1001: domain 1 of 1, from 277 to 344: score 86.0, E = 5.2e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sHELRTPL+aI+gyael + ++ ++l++ +
AE016958_1 277 RMRQFITDASHELRTPLAAIQGYAELTRQDS-------STLPPTT-- 314

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l +i++ea+r+ L+++lL lsr+++g
AE016958_1 315 ----------EYALARIESEARRMALLVDELLLLSRLGEG 344

AE016958_0260: domain 1 of 1, from 269 to 335: score 83.4, E = 2.8e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a++sHELRTPL+aIrgy+el ++ + e +
AE016958_0 269 RVRQFVADASHELRTPLAAIRGYTELTQR---------MGDDREAV- 305

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++ +e+er+ rL++dlL l+r+++g
AE016958_0 306 ----------AQAMSRVASETERMTRLVEDLLLLARLDSG 335

AE016958_3359: domain 1 of 1, from 294 to 361: score 73.9, E = 1.4e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f++++sHELRTPLt++r++a+l+ + ++++l++
AE016958_3 294 LQRRFTSDVSHELRTPLTTVRMAADLIYD-------HSADLDPTL-- 331

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ +e + +e++r ++L+ndlL++sr +ag
AE016958_3 332 ----------ARSTELMVNELDRFESLLNDLLEISRHDAG 361

AE016958_3982: domain 1 of 1, from 156 to 222: score 72.3, E = 4e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+an+sHEL+TP+ a+ ++ae+Ll+ ++ ++e++
AE016958_3 156 TRRDFVANVSHELKTPVGAMALLAEALLA---------SADDSETV- 192

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++ e++l ea+rl +++ +l +lsr++
AE016958_3 193 ----------RRFAEKVLVEANRLGDMVAELIELSRLQGA 222

AE016958_0592: domain 1 of 1, from 249 to 313: score 71.1, E = 9.1e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sHELRTPLt+Irg+ael + ++ + ++
AE016958_0 249 RMRRFITDASHELRTPLTTIRGFAELYRQGA-----------ARDV- 283

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l++i++ea r+ L++dlL l+r++ +
AE016958_0 284 ----------AMLLSRIESEASRMGLLVDDLLLLARLDVQ 313

AE016958_0996: domain 1 of 1, from 628 to 696: score 63.3, E = 1.5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +l+++sH+LRTPL+a + +++ L++ +d + s+ ++
AE016958_0 628 LRRSLLSAVSHDLRTPLAAAKVAVSSLRA-------EDVAFSPTDT- 666

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+l ti++++++l +L+ +lLd sr+ ag
AE016958_0 667 ----------AELLATIEESIDQLTALVGNLLDSSRLAAG 696

AE016958_0917: domain 1 of 1, from 232 to 304: score 61.4, E = 4.9e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +++ ++ HELRTPLt++r+++elL + ++ +g + l+e+++
AE016958_0 232 RQARLVTDAGHELRTPLTSLRTNVELLMASME---PGAPRLPEQEM- 274

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+ +l ++e l+ L+ dl dl+r +ag
AE016958_0 275 ----------VELRADVLAQIEELSTLVGDLVDLTRDDAG 304

AE016958_1222: domain 1 of 1, from 257 to 325: score 58.0, E = 4.5e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++fl +++HELRTP+++++ +ae L ++ +e +++ +
AE016958_1 257 ATRRFLVDAAHELRTPIAGMQVAAEQLAHGA-------SEHPDDGQ- 295

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l++a+r rL+nd+Ldlsri+ag
AE016958_1 296 ----------YRRAGLLLSDARRAGRLVNDMLDLSRIDAG 325

AE016958_1101: domain 1 of 1, from 245 to 310: score 55.4, E = 2.4e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+ ++sHELR PLt+I+ +e++++ +++l
AE016958_1 245 AQQRFVGDASHELRSPLTTIISGLEVAEA-------------HPELL 278

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + +++t+l ea+r+++Li+dlL l+r+++
AE016958_1 279 DA--------ELAVNTLLPEAHRMRALIDDLLLLARADER 310

AE016958_0153: domain 1 of 1, from 222 to 288: score 54.5, E = 4.5e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a +sHELRTPLta+r+++e+L + +l+ eqr
AE016958_0 222 SARDFAAVASHELRTPLTAMRTNLEVLST---------LDLPHEQR- 258

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e + ++r r+++ + l l++ e
AE016958_0 259 ----------QEVIGDVIRTQSRIEATLTALERLAQGELT 288

AE016958_3390: domain 1 of 1, from 290 to 358: score 48.0, E = 3.1e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ +sH+L PL + +++lL++++ +++ +e
AE016958_3 290 ELEQFAYVASHDLQEPLRKVASFCQLLERRY-------GDQLDERG- 328

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
ey+ + + a+r+++LindlL++sr +
AE016958_3 329 ----------LEYIGFAVDGAKRMQALINDLLTFSRVGRL 358

AE016958_0833: domain 1 of 1, from 229 to 295: score 47.1, E = 5.5e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f a +HELR PLta+r+++e+L + ++++eqr
AE016958_0 229 SARDFSAVTAHELRSPLTAMRTNLEVLST---------LDMPDEQR- 265

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e l ++r r++ + l l++ e
AE016958_0 266 ----------KEVLGDVIRTQSRIETTLTALERLAQGELS 295


Histogram of all scores:
score obs exp (one = represents 16 sequences)
----- --- ---
-14 3 0|=
-13 34 3|*==
-12 160 99|======*===
-11 371 515|======================== *
-10 773 956|================================================= *
-9 901 987|========================================================= *
-8 771 739|==============================================*==
-7 577 466|=============================*=======
-6 331 268|================*====
-5 176 147|=========*=
-4 97 78|====*==
-3 72 41|==*==
-2 31 21|=*
-1 25 11|*=
0 9 5|*
1 3 3|*
2 2 1|*
3 0 0|
> 4 14 -|=


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 216.4548
P(chi-square) = 2.44e-309

Total sequences searched: 4350

Whole sequence top hits:
tophits_s report:
Total hits: 12
Satisfying E cutoff: 12
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 12
Satisfying E cutoff: 12
Total memory: 25K


Acknowledgements:

This research is funded by:

Developed by: