Acidobacteria Actinobacteria Alphaproteobacteria
Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria
Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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264 projects found  

5 accessions found for Yersinia pestis biovar Microtus str. 91001  

Data for AE017042  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AE017042.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AE017042_0713 CDS_787671-788987 88.2 1.2e-24 1
AE017042_0399 CDS_438187-435398 86.8 2.8e-24 1
AE017042_0298 CDS_319794-317029 85.9 5e-24 1
AE017042_0894 CDS_989082-986209 79.3 3.7e-22 1
AE017042_3675 CDS_4336631-4334295 75.7 4.1e-21 1
AE017042_1786 CDS_2058859-2057468 69.5 2.2e-19 1
AE017042_2457 CDS_2814024-2815475 68.8 3.6e-19 1
AE017042_2543 CDS_2919404-2920948 67.1 1.1e-18 1
AE017042_2626 CDS_3019103-3020434 67.0 1.2e-18 1
AE017042_1615 CDS_1838800-1834931 65.8 2.5e-18 1
AE017042_0072 CDS_83409-82033 63.6 1.1e-17 1
AE017042_0024 CDS_32703-31624 62.4 2.3e-17 1
AE017042_2410 CDS_2763874-2761148 61.1 5.5e-17 1
AE017042_3461 CDS_4086586-4085168 58.1 4e-16 1
AE017042_2534 CDS_2906711-2905362 53.9 5.8e-15 1
AE017042_0135 CDS_150137-151489 53.3 8.6e-15 1
AE017042_0955 CDS_1061378-1059555 53.0 1.1e-14 1
AE017042_0564 CDS_615483-614416 46.9 5.9e-13 1
AE017042_3212 CDS_3721360-3723915 40.4 4e-11 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AE017042_0713 1/1 203 269 .. 1 87 [] 88.2 1.2e-24
AE017042_0399 1/1 387 452 .. 1 87 [] 86.8 2.8e-24
AE017042_0298 1/1 291 356 .. 1 87 [] 85.9 5e-24
AE017042_0894 1/1 479 544 .. 1 87 [] 79.3 3.7e-22
AE017042_3675 1/1 282 347 .. 1 87 [] 75.7 4.1e-21
AE017042_1786 1/1 240 306 .. 1 87 [] 69.5 2.2e-19
AE017042_2457 1/1 257 325 .. 1 87 [] 68.8 3.6e-19
AE017042_2543 1/1 280 350 .. 1 87 [] 67.1 1.1e-18
AE017042_2626 1/1 219 283 .. 1 87 [] 67.0 1.2e-18
AE017042_1615 1/1 739 803 .. 1 87 [] 65.8 2.5e-18
AE017042_0072 1/1 238 300 .. 1 87 [] 63.6 1.1e-17
AE017042_0024 1/1 139 204 .. 1 87 [] 62.4 2.3e-17
AE017042_2410 1/1 665 732 .. 1 87 [] 61.1 5.5e-17
AE017042_3461 1/1 255 320 .. 1 87 [] 58.1 4e-16
AE017042_2534 1/1 228 291 .. 1 87 [] 53.9 5.8e-15
AE017042_0135 1/1 233 293 .. 1 87 [] 53.3 8.6e-15
AE017042_0955 1/1 373 439 .. 1 87 [] 53.0 1.1e-14
AE017042_0564 1/1 136 196 .. 1 87 [] 46.9 5.9e-13
AE017042_3212 1/1 497 559 .. 1 87 [] 40.4 4e-11

Alignments of top-scoring domains:
AE017042_0713: domain 1 of 1, from 203 to 269: score 88.2, E = 1.2e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e++ + +el + r
AE017042_0 203 ARRNFFANVSHELRTPLTVLQGYLEMMHD---------QELAGPLR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l t++++++r++ L+ +lL+lsriea
AE017042_0 240 ----------DKALGTMQEQTKRMDGLVKQLLTLSRIEAA 269

AE017042_0399: domain 1 of 1, from 387 to 452: score 86.8, E = 2.8e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks+ l ++sHE+RTPL++ +g++elL++ t+l++ q
AE017042_0 387 RKSDHLTTISHEIRTPLNGALGAVELLQN---------TPLDAGQ-- 422

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ et+++++ +ll++in+lLd+srie+g
AE017042_0 423 ----------MRLAETAHQCSLSLLAIINNLLDFSRIESG 452

AE017042_0298: domain 1 of 1, from 291 to 356: score 85.9, E = 5e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l+ t l++ q
AE017042_0 291 IKSEFLANMSHELRTPLNGVIGFTRQTLK---------TSLTPTQ-- 326

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+yl+ti+r+a+ ll +ind+Ld+s++ea
AE017042_0 327 ----------TDYLQTIQRSANNLLCIINDVLDFSKLEAD 356

AE017042_0894: domain 1 of 1, from 479 to 544: score 79.3, E = 3.7e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
AE017042_0 479 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPQGV-- 514

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
AE017042_0 515 ----------DRLVTAMNNSSGLLLKIISDILDFSKIESE 544

AE017042_3675: domain 1 of 1, from 282 to 347: score 75.7, E = 4.1e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ tel++eq
AE017042_3 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TELDAEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+yl+ti+ +a l ++ nd+ ++ ++e
AE017042_3 318 ----------LKYLKTIHVSAITLGNIFNDIIEMDKLERR 347

AE017042_1786: domain 1 of 1, from 240 to 306: score 69.5, E = 2.2e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f a+++HELRTPLt ++g ++l l ++ ++
AE017042_1 240 QLESFNADVAHELRTPLTNLMGQTQLGLS---------RKRETHEL- 276

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++le+ l+e+er+ +++nd+L ls ++ag
AE017042_1 277 ----------EDLLESNLEELERMTSIVNDMLFLSHAQAG 306

AE017042_2457: domain 1 of 1, from 257 to 325: score 68.8, E = 3.6e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ efl+++sHEL+TPL+++r +elL +e+ ++l+ +q
AE017042_2 257 QRHEFLRHISHELKTPLASMREGTELLADEVA------GPLTQDQ-- 295

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e + ++++++++l++Li++lLd+ r a
AE017042_2 296 ----------QEVVAILDHSSRHLQQLIEQLLDYNRKLAD 325

AE017042_2543: domain 1 of 1, from 280 to 350: score 67.1, E = 1.1e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ f+ +sHEL+TPLt I +yae+L+e l+ ++ ++
AE017042_2 280 QQVSFVGQVSHELKTPLTNITLYAEMLQE-----LQPEQSVPPTAE- 320

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yle+il+e++rl+rLi+++L ++++
AE017042_2 321 ----------QRYLEVILNESQRLSRLIQNILSFTKAPKL 350

AE017042_2626: domain 1 of 1, from 219 to 283: score 67.0, E = 1.2e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPL+++rg +e+L+++l ++e
AE017042_2 219 MRRDFMADVSHELRTPLAVLRGELEALQDGL-------RQPTPES-- 256

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l++++ e+ l +L+ndl +ls+ + g
AE017042_2 257 -------------LSSLQAEVAILTKLVNDLHQLSQSDRG 283

AE017042_1615: domain 1 of 1, from 739 to 803: score 65.8, E = 2.5e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ks fla++sHELRTP+ aI+g++el + ++++ e+
AE017042_1 739 TKSTFLATISHELRTPMYAIMGLLELEIR---------SNRPVEK-- 774

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ l t+ ++a++l L++d+ d ++ieag
AE017042_1 775 -----------DTLVTVSKSAQSLMLLLDDIIDSAKIEAG 803

AE017042_0072: domain 1 of 1, from 238 to 300: score 63.6, E = 1.1e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++++++++sHELRTPLt +++++ l+++ + ++
AE017042_0 238 AQQRLISDISHELRTPLTRLQLATALMRR---------RHGEGKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL lsr ++
AE017042_0 274 -------------LERIEMEAQRLDSMINDLLVLSRSQHK 300

AE017042_0024: domain 1 of 1, from 139 to 204: score 62.4, E = 2.3e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
AE017042_0 139 AARDLVRGLAHEIKNPLGGLRGAAQLLAK----------ALPDPAL- 174

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
ey+++i+++a+rl++L+++lL r ++
AE017042_0 175 ----------LEYTQVIIEQADRLRNLVDRLLGPQRPGQH 204

AE017042_2410: domain 1 of 1, from 665 to 732: score 61.1, E = 5.5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l ++ ++ +
AE017042_2 665 LRNSLLAALSHDLRTPLTVLFGQAEILTLDL-------AAEGSRH-- 702

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + i++++ + rL+n+lLd++ri++g
AE017042_2 703 ----------APQANQIRQQVLSTTRLVNNLLDMARIQSG 732

AE017042_3461: domain 1 of 1, from 255 to 320: score 58.1, E = 4e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l HEL+ PL+aI+g+aelL+e ++ +e
AE017042_3 255 YIEQYVHTLTHELKSPLAAISGAAELLRE---------SPPPETA-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l i++++ r+++L++ +L +r+e+
AE017042_3 291 ----------QRFLINIEQQSARIQQLVDKMLVQARLESR 320

AE017042_2534: domain 1 of 1, from 228 to 291: score 53.9, E = 5.8e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++++l ++sHELR PL+ +++++ l ++++++ +
AE017042_2 228 AREQLLHDVSHELRSPLARLQLAIGL------------AHQNPDNV- 261

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+l++i++e+erl+++i +lL lsr+e+
AE017042_2 262 ----------DNALQRIEHESERLDKMIGELLALSRAENH 291

AE017042_0135: domain 1 of 1, from 233 to 293: score 53.3, E = 8.6e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ + ++
AE017042_0 233 DRTLLMAGVSHDLRTPLTRIRLATEMMSD--------------DD-- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + e+i +++e ++++i+++ d+ r +++
AE017042_0 264 ----------AYLSESINKDIEECNAIIEQFIDYLRTGQE 293

AE017042_0955: domain 1 of 1, from 373 to 439: score 53.0, E = 1.1e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + ++a+++HE+R+PL++I+g+a+ + +++++e+
AE017042_0 373 AIGNLAAGVAHEIRNPLSSIKGFAKYFEG--------HSPQGSEE-- 409

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+ +++++e++rl+r + +lL l r
AE017042_0 410 ----------QELAKVMIKEVDRLNRAVTELLGLVRPSDL 439

AE017042_0564: domain 1 of 1, from 136 to 196: score 46.9, E = 5.9e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + f+a+++HELRTPL++Ir+++el+++ + e +
AE017042_0 136 QERLFTADAAHELRTPLAGIRLHLELMEK---------QGIAESK-- 171

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++ ++ l + i++lL lsr++++
AE017042_0 172 ---------------SLINRIDLLMHTIEQLLMLSRAGQN 196

AE017042_3212: domain 1 of 1, from 497 to 559: score 40.4, E = 4e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++ +l+H++++ L++I+g +el + + s+ +r
AE017042_3 497 AVGQLTGGLAHDFNNLLAVIIGSLELTAT----------DSSDATR- 532

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++l++aer +L ++lL +sr ++
AE017042_3 533 -------------IHRALKAAERGAQLTQRLLAFSRKQSL 559


Histogram of all scores:
score obs exp (one = represents 12 sequences)
----- --- ---
-14 27 0|===
-13 57 2|*====
-12 205 89|=======*==========
-11 368 461|=============================== *
-10 641 856|====================================================== *
-9 707 884|==========================================================*
-8 690 662|=======================================================*==
-7 487 417|==================================*======
-6 291 240|===================*=====
-5 181 131|==========*=====
-4 104 70|=====*===
-3 50 37|===*=
-2 24 19|=*
-1 25 10|*==
0 5 5|*
1 4 2|*
2 3 1|*
3 1 0|=
4 3 0|=
5 0 0|
6 1 0|=
> 7 21 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 344.6039
P(chi-square) = 0

Total sequences searched: 3895

Whole sequence top hits:
tophits_s report:
Total hits: 19
Satisfying E cutoff: 19
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 19
Satisfying E cutoff: 19
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: