Acidobacteria Actinobacteria Alphaproteobacteria
Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria
Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
Search:
7 projects found  

2 accessions found for Thermus thermophilus HB27  

Data for AE017221  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AE017221.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
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Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AE017221_0776 CDS_762492-759601 90.8 1.1e-25 1
AE017221_1133 CDS_1108703-1110109 85.5 3.3e-24 1
AE017221_0463 CDS_451859-449358 76.8 9.7e-22 1
AE017221_1355 CDS_1294527-1295648 66.9 6.2e-19 1
AE017221_1222 CDS_1191327-1190023 63.9 4.5e-18 1
AE017221_0992 CDS_977510-978763 60.7 3.5e-17 1
AE017221_0644 CDS_633007-634224 44.8 1.2e-12 1
AE017221_1844 CDS_1756531-1757424 30.1 1.6e-08 1
AE017221_0388 CDS_377787-376813 27.6 8.8e-08 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AE017221_0776 1/1 736 801 .. 1 87 [] 90.8 1.1e-25
AE017221_1133 1/1 246 312 .. 1 87 [] 85.5 3.3e-24
AE017221_0463 1/1 613 679 .. 1 87 [] 76.8 9.7e-22
AE017221_1355 1/1 146 209 .. 1 87 [] 66.9 6.2e-19
AE017221_1222 1/1 231 292 .. 1 87 [] 63.9 4.5e-18
AE017221_0992 1/1 214 276 .. 1 87 [] 60.7 3.5e-17
AE017221_0644 1/1 198 261 .. 1 87 [] 44.8 1.2e-12
AE017221_1844 1/1 99 159 .. 1 87 [] 30.1 1.6e-08
AE017221_0388 1/1 116 183 .. 1 87 [] 27.6 8.8e-08

Alignments of top-scoring domains:
AE017221_0776: domain 1 of 1, from 736 to 801: score 90.8, E = 1.1e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+efla++sHELRTPL+aI+g+aelL+ ++l++e
AE017221_0 736 LKGEFLAAVSHELRTPLAAILGLAELLRQ---------EPLPPEA-- 771

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e +e il++a rl +++++lLd sr+eag
AE017221_0 772 ----------QESVELILESAFRLKNMVDNLLDTSRLEAG 801

AE017221_1133: domain 1 of 1, from 246 to 312: score 85.5, E = 3.3e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++fl ++sHELRTP+taI+g++ Ll+ +t+l+e q
AE017221_1 246 AQTRFLQDASHELRTPITAILGHVGYLLR--------RTPLTEAQ-- 282

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re le+++reaer+ +L++dlLdls+ ++
AE017221_1 283 ----------RESLEVVKREAERMGKLVSDLLDLSQSGTW 312

AE017221_0463: domain 1 of 1, from 613 to 679: score 76.8, E = 9.7e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+efla++sHEL+TPLta+r++ae+L +e +ee+r
AE017221_0 613 LKDEFLATVSHELKTPLTAVRALAEILAQ---------EEVGEEER- 649

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+++ + +ea rl+rL++++L ++r+ea
AE017221_0 650 ----------RRFTALLAQEAARLSRLVEEILAYTRLEAR 679

AE017221_1355: domain 1 of 1, from 146 to 209: score 66.9, E = 6.2e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ e++ +++HELRTPL+a++gyae L + + ls e++
AE017221_1 146 TRAELIGTVAHELRTPLAALQGYAEGLMD---------GVLSKEKA- 182

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e ilre++ ++rL++dl sr ea
AE017221_1 183 -------------AEGILREVKAMRRLVEDLSLVSRVEAK 209

AE017221_1222: domain 1 of 1, from 231 to 292: score 63.9, E = 4.5e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++f++++sHELRTPLta++gy+e+L++ +
AE017221_1 231 AARRFARHASHELRTPLTALKGYLEVLRR-------------KNE-- 262

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++le +lrea r+++L+ lL lsr+ea
AE017221_1 263 ----------PRALEGALREAGRMEALLAGLLRLSRLEAL 292

AE017221_0992: domain 1 of 1, from 214 to 276: score 60.7, E = 3.5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + fla +sHELRTPLt+++g+++ L + ++++
AE017221_0 214 RERAFLAEASHELRTPLTVLLGHLDRLGR------------NPQD-- 246

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+l+t++ aer++rL++dlL l+r e +
AE017221_0 247 ----------LEALRTARATAERMRRLVEDLLALARGEVE 276

AE017221_0644: domain 1 of 1, from 198 to 261: score 44.8, E = 1.2e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +f+++++HELRTP++a ++ +e+++ ++ +
AE017221_0 198 REKRFTRDAAHELRTPVAAALAQLEAAEGGY-----------LSE-- 231

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+l+ ++e+ r+ rL++ lL l+r +
AE017221_0 232 ----------GEALQATKEELLRMKRLVEALLVLAREGRV 261

AE017221_1844: domain 1 of 1, from 99 to 159: score 30.1, E = 1.6e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +e a l+HE+RTPL+++ ++ +L +++ +
AE017221_1 99 EAEEAGALLAHEFRTPLAGMAVLLRALAP-----------KDPRE-- 132

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l+ +++e+ rl rL++ l + ++ g
AE017221_1 133 ----------AQVLDLLKKEVARLTRLVESL---AHLRPG 159

AE017221_0388: domain 1 of 1, from 116 to 183: score 27.6, E = 8.8e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ + a+l+H+L+TPL + + +++ L++ ++l+ e r
AE017221_0 116 AREALYAALAHDLKTPLLSALRLLDYLER--------ADDLGKERR- 153

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+l+ +++e+ r rL ++lL l+r+ea
AE017221_0 154 ----------VALLRALREELARGYRLTENLLALARLEAR 183


Histogram of all scores:
score obs exp (one = represents 7 sequences)
----- --- ---
-15 1 0|=
-14 2 0|=
-13 19 1|*==
-12 75 45|======*====
-11 154 234|====================== *
-10 324 435|=============================================== *
-9 367 450|===================================================== *
-8 332 336|===============================================*
-7 272 212|==============================*========
-6 183 122|=================*=========
-5 100 67|=========*=====
-4 64 35|====*=====
-3 25 18|==*=
-2 25 9|=*==
-1 12 5|*=
0 10 2|*=
1 2 1|*
> 2 15 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 210.2926
P(chi-square) = 1.025e-308

Total sequences searched: 1982

Whole sequence top hits:
tophits_s report:
Total hits: 9
Satisfying E cutoff: 9
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 9
Satisfying E cutoff: 9
Total memory: 24K


Acknowledgements:

This research is funded by:

Developed by: