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2 accessions found for Brucella abortus bv. 1 str. 9-941  

Data for AE017223  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AE017223.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AE017223_0587 CDS_633114-630763 90.3 1.5e-25 1
AE017223_1495 CDS_1567998-1571105 89.7 2.3e-25 1
AE017223_0301 CDS_332115-333431 85.6 3.3e-24 1
AE017223_1943 CDS_2030547-2032352 72.5 1.7e-20 1
AE017223_1950 CDS_2035921-2038500 71.3 3.7e-20 1
AE017223_0553 CDS_591452-593281 63.3 6.6e-18 1
AE017223_1041 CDS_1114475-1113333 55.3 1.3e-15 1
AE017223_0584 CDS_623859-625262 47.5 2e-13 1
AE017223_0319 CDS_352550-349026 45.0 1e-12 1
AE017223_1039 CDS_1111770-1109446 42.4 5.5e-12 1
AE017223_0120 CDS_150203-151495 40.1 2.5e-11 1
AE017223_0970 CDS_1022936-1025773 39.5 3.8e-11 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AE017223_0587 1/1 543 612 .. 1 87 [] 90.3 1.5e-25
AE017223_1495 1/1 795 864 .. 1 87 [] 89.7 2.3e-25
AE017223_0301 1/1 200 267 .. 1 87 [] 85.6 3.3e-24
AE017223_1943 1/1 364 429 .. 1 87 [] 72.5 1.7e-20
AE017223_1950 1/1 627 695 .. 1 87 [] 71.3 3.7e-20
AE017223_0553 1/1 328 397 .. 1 87 [] 63.3 6.6e-18
AE017223_1041 1/1 135 199 .. 1 87 [] 55.3 1.3e-15
AE017223_0584 1/1 240 306 .. 1 87 [] 47.5 2e-13
AE017223_0319 1/1 801 866 .. 1 87 [] 45.0 1e-12
AE017223_1039 1/1 525 596 .. 1 87 [] 42.4 5.5e-12
AE017223_0120 1/1 209 275 .. 1 87 [] 40.1 2.5e-11
AE017223_0970 1/1 567 633 .. 1 87 [] 39.5 3.8e-11

Alignments of top-scoring domains:
AE017223_0587: domain 1 of 1, from 543 to 612: score 90.3, E = 1.5e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
akseflan+sHELRTPL+aI+g++e+++++ + ++l+++
AE017223_0 543 AKSEFLANMSHELRTPLNAIIGFSEMIQAGTF------GPLGSDR-- 581

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ey++ i+ +++ ll+ ind+Ld+s+ieag
AE017223_0 582 ---------YEEYINDIHTSGNFLLNVINDILDMSKIEAG 612

AE017223_1495: domain 1 of 1, from 795 to 864: score 89.7, E = 2.3e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k+efla +sHE+RTPL+aI+g++el+ + + ++ + +
AE017223_1 795 QKTEFLARISHEIRTPLNAIIGFSELMAD------EKFGPIGNDR-- 833

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr+yl+ i r++++ l+L+ndlLd+s+ieag
AE017223_1 834 ---------YRDYLRDINRSGNHVLALVNDLLDISKIEAG 864

AE017223_0301: domain 1 of 1, from 200 to 267: score 85.6, E = 3.3e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f+an+sHELRTPL+++rg++e+L+ +++++ ++
AE017223_0 200 MRSDFIANASHELRTPLASLRGFIETLQG---------PARNDAAAR 237

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l++++++aer++rLi+dlL lsr+e
AE017223_0 238 ----------DRFLDIMQKQAERMSRLIDDLLSLSRLEMR 267

AE017223_1943: domain 1 of 1, from 364 to 429: score 72.5, E = 1.7e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + f+a++sHEL++PLt++r ++e+L ++++e r
AE017223_1 364 AIESFAADVSHELKNPLTSLRSAVETLPL----------AKTDESR- 399

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l++i+++++rl+rLi d+ d sr++a+
AE017223_1 400 ----------KRLLDVIQHDVRRLDRLITDISDASRLDAE 429

AE017223_1950: domain 1 of 1, from 627 to 695: score 71.3, E = 3.7e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k++f+ ++s ELR PLt I+g++elL++ + + l+e q
AE017223_1 627 IKNDFVQHVSYELRSPLTNIIGFTELLQT------PAFGSLNERQ-- 665

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
eyl+ i ++ ll ++nd+Ldl+ +ag
AE017223_1 666 ----------LEYLDYISTSSSVLLTIVNDILDLATVDAG 695

AE017223_0553: domain 1 of 1, from 328 to 397: score 63.3, E = 6.6e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+++la++sHELRTPL++I+g++++L + ++l ++ +
AE017223_0 328 GKGRLLATVSHELRTPLNSIIGFSDMLTH------EIGGKLASDRQ- 367

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
rey i++++++ll+L+n +Ld sr+e+g
AE017223_0 368 ----------REYAGLIHQSGHYLLELVNAVLDNSRLETG 397

AE017223_1041: domain 1 of 1, from 135 to 199: score 55.3, E = 1.3e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + ++++l+HE+++PL++Irg+a+lL+ s+e+
AE017223_1 135 SVTGLASMLAHEIKNPLSGIRGAAQLLEQ----------VVSDED-- 169

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r + + i +e++r+ +L++++ +s +
AE017223_1 170 ----------RALARLITEETDRIVSLVDRMEVFSDERPI 199

AE017223_0584: domain 1 of 1, from 240 to 306: score 47.5, E = 2e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + n++H+L+TPLt +r ae +l +e+ e++
AE017223_0 240 GLKQVSDNIAHDLKTPLTRLRNRAEEALG---------GEKVEPE-- 275

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr +le i+ e+++l r n +L +sr+e+g
AE017223_0 276 ---------YRAALEDIIGESDQLIRTFNAILMISRLETG 306

AE017223_0319: domain 1 of 1, from 801 to 866: score 45.0, E = 1e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k++fla++ H++ +PL+a r+y+ +L e +l+ ++
AE017223_0 801 GKTRFLAAAGHDILQPLNAARLYSTALAE----------KLGRSET- 836

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+ + i++++e ++++ +Ld+sr+++g
AE017223_0 837 ----------SEFARNIDSSLEAVEAILGMVLDISRLDTG 866

AE017223_1039: domain 1 of 1, from 525 to 596: score 42.4, E = 5.5e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + ++ ++HE+++PLt I++ ae +++++ ++ + + e
AE017223_1 525 AWADVARRIAHEIKNPLTPIQLSAERIRRRY----GKVITEDREV-- 565

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + ++ti+r++ + r+++++ ++r+ +
AE017223_1 566 ---------FDQCTDTIIRQVGDIGRMVDEFSAFARMPKP 596

AE017223_0120: domain 1 of 1, from 209 to 275: score 40.1, E = 2.5e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HEL TPL++I + ++ +++ +++++
AE017223_0 209 ALDGLAAAAAHELGTPLATIALVVKEMQR--------AHTKDPGL-- 245

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e + ++++++r+++++++l ls +++
AE017223_0 246 ----------EEDIALLHSQTQRCREILQRLTSLSSEGEE 275

AE017223_0970: domain 1 of 1, from 567 to 633: score 39.5, E = 3.8e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++ +++H++++ LtaI++ ++lLl++ + +s++
AE017223_0 567 AVGQLAGGIAHDFNNVLTAIIMSSDLLLTN--------HRASDPS-- 603

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ i++ a+r +L+++lL +sr ++
AE017223_0 604 ----------FPDIMNIKQNANRAASLVRQLLAFSRRQTL 633


Histogram of all scores:
score obs exp (one = represents 7 sequences)
----- --- ---
-15 2 0|=
-14 15 0|===
-13 38 1|*=====
-12 132 46|======*============
-11 232 240|==================================*
-10 340 446|================================================= *
-9 392 461|======================================================== *
-8 322 345|============================================== *
-7 235 217|==============================*===
-6 134 125|=================*==
-5 80 68|=========*==
-4 47 36|=====*=
-3 21 19|==*
-2 11 10|=*
-1 7 5|*
0 4 2|*
1 1 1|*
2 0 0|
3 1 0|=
> 4 16 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 202.9642
P(chi-square) = 1.804e-37

Total sequences searched: 2030

Whole sequence top hits:
tophits_s report:
Total hits: 12
Satisfying E cutoff: 12
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 12
Satisfying E cutoff: 12
Total memory: 25K


Acknowledgements:

This research is funded by:

Developed by: