Acidobacteria Actinobacteria Alphaproteobacteria
Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria
Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
Search:
264 projects found  

1 accessions found for Legionella pneumophila subsp. pneumophila str. Philadelphia 1  

Data for AE017354  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AE017354.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AE017354_1874 CDS_2133598-2136330 99.0 7.4e-28 1
AE017354_2104 CDS_2394053-2391603 91.6 9e-26 2
AE017354_2137 CDS_2451717-2454203 70.4 9.3e-20 1
AE017354_1151 CDS_1296252-1297838 59.2 1.4e-16 1
AE017354_1266 CDS_1420091-1418676 56.6 7.5e-16 1
AE017354_1411 CDS_1587319-1585925 52.0 1.6e-14 1
AE017354_1734 CDS_1969333-1968302 47.4 3.2e-13 1
AE017354_0695 CDS_780667-779576 42.9 6e-12 1
AE017354_2410 CDS_2773103-2771823 35.1 9.8e-10 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AE017354_1874 1/1 297 362 .. 1 87 [] 99.0 7.4e-28
AE017354_2137 1/1 288 353 .. 1 87 [] 70.4 9.3e-20
AE017354_2104 1/2 194 260 .. 1 87 [] 63.4 9e-18
AE017354_1151 1/1 310 376 .. 1 87 [] 59.2 1.4e-16
AE017354_1266 1/1 246 311 .. 1 87 [] 56.6 7.5e-16
AE017354_1411 1/1 240 304 .. 1 87 [] 52.0 1.6e-14
AE017354_1734 1/1 126 192 .. 1 87 [] 47.4 3.2e-13
AE017354_0695 1/1 144 210 .. 1 87 [] 42.9 6e-12
AE017354_2410 1/1 206 274 .. 1 87 [] 35.1 9.8e-10
AE017354_2104 2/2 592 660 .. 1 87 [] 28.2 8.5e-08

Alignments of top-scoring domains:
AE017354_1874: domain 1 of 1, from 297 to 362: score 99.0, E = 7.4e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ksef+an+sHE+RTP+++++g++ +Lle ++l++ q
AE017354_1 297 QKSEFIANMSHEIRTPMNGVIGFTNVLLE---------SKLDPLQ-- 332

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+y++ti+++a+ ll++ind+Ld+s+i+ag
AE017354_1 333 ----------LDYVKTIKSSAQDLLSIINDILDFSKIDAG 362

AE017354_2137: domain 1 of 1, from 288 to 353: score 70.4, E = 9.3e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ef+an+sH+LRTPL+++ g+ael++e + ++ q
AE017354_2 288 VKTEFIANMSHDLRTPLSGVVGMAELMKE---------QVTDPVQ-- 323

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+y e i +++++ll+L++ +Ld+ +++
AE017354_2 324 ----------VQYAEWIFDCSQQLLSLLDGILDIVSLGNV 353

AE017354_2104: domain 1 of 2, from 194 to 260: score 63.4, E = 9e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k++f+an+sHELRTPL I+ +e+Ll+ + +l++
AE017354_2 194 IKTQFFANVSHELRTPLMLILDPLEMLLA--------EKKLPSFV-- 230

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ l++i++ a+ ll+ +ndlL +s+++ag
AE017354_2 231 ----------QNTLRRIQNNAQILLKHVNDLLNISKLDAG 260

AE017354_1151: domain 1 of 1, from 310 to 376: score 59.2, E = 1.4e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f a+++HELR+PL aI +++l ++ ++l+ee
AE017354_1 310 ALGRFSASIAHELRNPLGAIAHAIQLFGDN--------EDLNEEN-- 346

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + i + er++r i ++L+lsr +
AE017354_1 347 ----------TRLKQLIMNNCERMNRVIKNVLQLSRRQKS 376

AE017354_1266: domain 1 of 1, from 246 to 311: score 56.6, E = 7.5e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +f+a+++HELRTPL+a+++ a+++l+ ++ ee+
AE017354_1 246 REKRFAADAAHELRTPLAALKAQAQVALN---------SNDIEEK-- 281

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l++++ +++r +++++lL++s++ +
AE017354_1 282 ----------NQALQKLIASVNRSTHIVQQLLTMSKLVPE 311

AE017354_1411: domain 1 of 1, from 240 to 304: score 52.0, E = 1.6e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k++++ ++sHELR PL+ ++ ++el +++ +l + +
AE017354_1 240 SKERLIQDISHELRSPLARLKIAIELGKKKT-------KHLADNE-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ e+ rl++Li ++Ld++r+e
AE017354_1 278 -------------FARMEIETSRLNDLIGEILDFARLEKS 304

AE017354_1734: domain 1 of 1, from 126 to 192: score 47.4, E = 3.2e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + ++a l+H++RTPL++ ++y+e L + + l+
AE017354_1 126 SIGTMTAQLAHQIRTPLSSAILYTEHLNN--------LPSLDHRI-- 162

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++++++ +++++i+dlL ++r +
AE017354_1 163 ----------KNWIHRLQECHASIEQQIQDLLLFARGTSI 192

AE017354_0695: domain 1 of 1, from 144 to 210: score 42.9, E = 6e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+f a+++HELR+P++ +r+++e+ l+ +++ e+
AE017354_0 144 HIKQFSASIAHELRNPIHYLRTATEITLT---------KPQTIET-- 179

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ l+t l+e ++l +Li++l l+r e+g
AE017354_0 180 ---------YQHVLQTHLEEYQSLTQLIDNLIFLTRCEHG 210

AE017354_2410: domain 1 of 1, from 206 to 274: score 35.1, E = 9.8e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ef +sH+L+ PL aI+ +a ++e+ +l++
AE017354_2 206 NLEEFSYIISHDLKAPLRAIIQLATWIEEDCG------NKLDSLS-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ +++ ++r++ +++ lL+++r++
AE017354_2 245 ----------RKNLQLLRERTRRMSGMVDGLLQYARAGRV 274

AE017354_2104: domain 2 of 2, from 592 to 660: score 28.2, E = 8.5e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sH+L+ PL a+ +++ ++e+l +e+ +eq
AE017354_2 592 ELDQFVYHASHDLKAPLPAMEHLISWIEEDL-------GEMLSEQS- 630

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl +++ a r+++L++ lL +++ +
AE017354_2 631 ----------KKYLLLLRQRASRMSKLLDGLLKYAQSGYV 660


Histogram of all scores:
score obs exp (one = represents 11 sequences)
----- --- ---
-15 1 0|=
-14 8 0|=
-13 44 2|*===
-12 136 67|======*======
-11 277 348|========================== *
-10 484 646|============================================ *
-9 601 668|======================================================= *
-8 465 500|=========================================== *
-7 357 315|============================*====
-6 229 181|================*====
-5 141 99|========*====
-4 81 53|====*===
-3 41 28|==*=
-2 27 14|=*=
-1 15 7|*=
0 11 4|*
1 7 2|*
2 3 1|*
3 1 0|=
4 1 0|=
5 0 0|
> 6 12 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 207.9819
P(chi-square) = 1.637e-38

Total sequences searched: 2942

Whole sequence top hits:
tophits_s report:
Total hits: 9
Satisfying E cutoff: 9
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 10
Satisfying E cutoff: 10
Total memory: 24K


Acknowledgements:

This research is funded by:

Developed by: