Acidobacteria Actinobacteria Alphaproteobacteria
Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria
Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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14 projects found  

1 accessions found for Dehalococcoides sp. CBDB1  

Data for AJ965256  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AJ965256.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AJ965256_0507 CDS_502128-499570 73.6 5.9e-21 1
AJ965256_0064 CDS_65088-66593 73.3 6.9e-21 1
AJ965256_0133 CDS_149120-150865 73.3 7.2e-21 1
AJ965256_1336 CDS_1278634-1281912 72.0 1.7e-20 1
AJ965256_0123 CDS_143021-139833 70.1 5.7e-20 1
AJ965256_1344 CDS_1289094-1293398 68.8 1.4e-19 1
AJ965256_1350 CDS_1297148-1299706 66.6 5.8e-19 1
AJ965256_0074 CDS_77239-76013 64.4 2.3e-18 1
AJ965256_0827 CDS_801894-798106 63.5 4.2e-18 1
AJ965256_0861 CDS_834239-835660 62.5 8e-18 1
AJ965256_1021 CDS_988611-987427 61.8 1.3e-17 1
AJ965256_1256 CDS_1197506-1198918 51.2 1.3e-14 1
AJ965256_1369 CDS_1321244-1322422 49.6 3.7e-14 1
AJ965256_1241 CDS_1184972-1186270 48.0 1.1e-13 1
AJ965256_1288 CDS_1230682-1232295 47.9 1.1e-13 1
AJ965256_0198 CDS_212773-210950 46.0 3.9e-13 1
AJ965256_1335 CDS_1278301-1276697 40.7 1.2e-11 1
AJ965256_1309 CDS_1252574-1250829 40.7 1.2e-11 1
AJ965256_1235 CDS_1179150-1180466 37.7 8.9e-11 1
AJ965256_0155 CDS_169512-167719 37.3 1.1e-10 1
AJ965256_0193 CDS_207874-206594 32.1 3.3e-09 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AJ965256_0507 1/1 632 697 .. 1 87 [] 73.6 5.9e-21
AJ965256_0064 1/1 268 336 .. 1 87 [] 73.3 6.9e-21
AJ965256_0133 1/1 359 426 .. 1 87 [] 73.3 7.2e-21
AJ965256_1336 1/1 731 797 .. 1 87 [] 72.0 1.7e-20
AJ965256_0123 1/1 830 895 .. 1 87 [] 70.1 5.7e-20
AJ965256_1344 1/1 1068 1134 .. 1 87 [] 68.8 1.4e-19
AJ965256_1350 1/1 488 554 .. 1 87 [] 66.6 5.8e-19
AJ965256_0074 1/1 165 230 .. 1 87 [] 64.4 2.3e-18
AJ965256_0827 1/1 901 967 .. 1 87 [] 63.5 4.2e-18
AJ965256_0861 1/1 246 310 .. 1 87 [] 62.5 8e-18
AJ965256_1021 1/1 142 207 .. 1 87 [] 61.8 1.3e-17
AJ965256_1256 1/1 242 308 .. 1 87 [] 51.2 1.3e-14
AJ965256_1369 1/1 168 233 .. 1 87 [] 49.6 3.7e-14
AJ965256_1241 1/1 214 278 .. 1 87 [] 48.0 1.1e-13
AJ965256_1288 1/1 313 378 .. 1 87 [] 47.9 1.1e-13
AJ965256_0198 1/1 362 427 .. 1 87 [] 46.0 3.9e-13
AJ965256_1335 1/1 302 367 .. 1 87 [] 40.7 1.2e-11
AJ965256_1309 1/1 362 427 .. 1 87 [] 40.7 1.2e-11
AJ965256_1235 1/1 204 270 .. 1 87 [] 37.7 8.9e-11
AJ965256_0155 1/1 357 423 .. 1 87 [] 37.3 1.1e-10
AJ965256_0193 1/1 198 259 .. 1 83 [. 32.1 3.3e-09

Alignments of top-scoring domains:
AJ965256_0507: domain 1 of 1, from 632 to 697: score 73.6, E = 5.9e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++e+ a+l+HEL++PLt+++g++el++e l+e+
AJ965256_0 632 SLGELSAGLAHELNNPLTSVIGFSELIQE---------KILPEDL-- 667

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ +++i +ea+r ++i++lL+++r ++
AJ965256_0 668 ----------RQDIQIISQEAQRAAEIIRNLLTFARRHEP 697

AJ965256_0064: domain 1 of 1, from 268 to 336: score 73.3, E = 6.9e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k e+l+ +sHELRTPLt+I+g+++ Ll+ +d ++++ ++
AJ965256_0 268 VKAELLSVVSHELRTPLTSIKGLTDSLLR-------KDVNWDDNTK- 306

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++le+i++e+ l+rLi+dlLd +++e +
AJ965256_0 307 ----------KDFLESIRSETGKLSRLIDDLLDTTKLERN 336

AJ965256_0133: domain 1 of 1, from 359 to 426: score 73.3, E = 7.2e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+an+sHELRTP+t++++++e+L+e +++s+++++
AJ965256_0 359 VRRDFVANISHELRTPITSLKLLTETLQE---------GAASDPDVA 396

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++++i+ e++ l +L+ +l dls ie+g
AJ965256_0 397 ----------AGFIDKIHLEVDKLAQLVTELSDLSAIESG 426

AJ965256_1336: domain 1 of 1, from 731 to 797: score 72.0, E = 1.7e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +e++a+++HE+++PLt+++g++elLle +++l+++
AJ965256_1 731 AVGEMAAGIAHEINNPLTGVIGFSELLLE--------REDLPDDI-- 767

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ l++i + ++r ++i ++L+++r ++
AJ965256_1 768 ----------KANLKIINDGSQRAKEIIKRMLTFARQTTP 797

AJ965256_0123: domain 1 of 1, from 830 to 895: score 70.1, E = 5.7e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +e++++l+HE+++PLt+I g++elLl+ el e
AJ965256_0 830 SVGELASGLAHEINNPLTGIVGFSELLLM---------NELEESI-- 865

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e ++ti+rea r +++++lL+++r ++
AJ965256_0 866 ----------KEDIQTIHREALRAAEIVRNLLTFARQHTP 895

AJ965256_1344: domain 1 of 1, from 1068 to 1134: score 68.8, E = 1.4e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +e++a+++HE+++PLt+++g+aelL + +++l+++
AJ965256_1 1068 AVGEMAAGIAHEINNPLTGVIGFAELLAN--------RPDLPADI-- 1104

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ +++i + + r +++ +lL+++r +
AJ965256_1 1105 ----------QDSIKIINNGSLRVVEIVKRLLTFARQTRP 1134

AJ965256_1350: domain 1 of 1, from 488 to 554: score 66.6, E = 5.8e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +e++a+++HE+++PLt+++g++elL + +++l+e+
AJ965256_1 488 AIGEMAAGIAHEINNPLTGVIGFSELLAA--------REDLPEDI-- 524

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l++i + ++r +++++lL+++r +
AJ965256_1 525 ----------MADLQVINHGSQRVVEIVRRLLTFARQNKP 554

AJ965256_0074: domain 1 of 1, from 165 to 230: score 64.4, E = 2.3e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ef+++l+HEL+TPLt+I+++ el+ + + ls+e
AJ965256_0 165 QRLEFTRALAHELKTPLTVIQAANELMGT---------QILSPEL-- 200

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++i r +++l++ +n+lLdl++ e g
AJ965256_0 201 ----------TNISDSIARGVQSLQKRVNELLDLAKGEVG 230

AJ965256_0827: domain 1 of 1, from 901 to 967: score 63.5, E = 4.2e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +e++a+++HE+++PLt+++g+a++L e +++l+++
AJ965256_0 901 AVGEMAAGIAHEINNPLTGVIGFASILME--------REDLPADV-- 937

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ l++i + ++r +++ ++L+++r +
AJ965256_0 938 ----------MDELQIINSGSQRVVEIVKRMLTFARQAKP 967

AJ965256_0861: domain 1 of 1, from 246 to 310: score 62.5, E = 8e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++la+++HELRTPLt+I g+++ +l+ + +++
AJ965256_0 246 SRQRLLADIAHELRTPLTVIEGTVDGMLD---------GVFAADT-- 281

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l ti++e+ l rLi dl+d+s +e+g
AJ965256_0 282 -----------HHLTTIKEESATLTRLIKDLRDISLAESG 310

AJ965256_1021: domain 1 of 1, from 142 to 207: score 61.8, E = 1.3e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + ++a+++HE++ PLt+I+g++e L + seeq
AJ965256_1 142 SVGALTAGVAHEINSPLTSILGFSERLAR---------KCTSEEQ-- 177

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ +e+i+ ea r + +n+l++++r ++
AJ965256_1 178 ----------HRDIERIHTEALRAAKVVNNLRTFARSYEQ 207

AJ965256_1256: domain 1 of 1, from 242 to 308: score 51.2, E = 1.3e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+++++HELRTPL+++++++ l +++s q
AJ965256_1 242 LQRRFVSDAAHELRTPLASVKTAVTHSLS---------GKRSISQ-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+e++ + + +e l++LindlL lsr+++
AJ965256_1 278 ---------YKELTILLSQRLEALENLINDLLFLSRADES 308

AJ965256_1369: domain 1 of 1, from 168 to 233: score 49.6, E = 3.7e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ f+++l HEL+TPLt++++++elL + +l ee +
AJ965256_1 168 QRITFTRALVHELKTPLTSMLATSELLSK----------NLAEEPN- 203

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y + ++ ++ l+ i++lLd++r e g
AJ965256_1 204 ----------LSYMKCLYAGIQDLNLRIDELLDIARGEVG 233

AJ965256_1241: domain 1 of 1, from 214 to 278: score 48.0, E = 1.1e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ef +l HEL+TPLt I +++e+L++ +l e
AJ965256_1 214 QRTEFYKALVHELKTPLTPIVLNSEVLED----------NLEGES-- 248

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + i ++ ll in+l d+++ e g
AJ965256_1 249 ----------KKLANNINIASLELLTRINELYDMAKGEVG 278

AJ965256_1288: domain 1 of 1, from 313 to 378: score 47.9, E = 1.1e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ef++ l HEL+TPLt I +++++Ll+ l+++++
AJ965256_1 313 KRTEFTRILIHELKTPLTPIVAASDMLLK----------ILPSDDT- 348

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + i + ae l++ ndl dl r e g
AJ965256_1 349 ----------HALAYQINKGAEELENRMNDLFDLVRGELG 378

AJ965256_0198: domain 1 of 1, from 362 to 427: score 46.0, E = 3.9e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ef+++l HEL+TPLt I++++++L l e
AJ965256_0 362 NRIEFTRALVHELKTPLTPIMAASDTLSS----------GLKQEP-- 396

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + i + a l++ i++lLdl+r e g
AJ965256_0 397 ---------WLNLAQNINKGALNLNKRIDELLDLARGEIG 427

AJ965256_1335: domain 1 of 1, from 302 to 367: score 40.7, E = 1.2e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f+++l HEL+TPLt +++ +e L els+ ++
AJ965256_1 302 QRNYFMRALVHELKTPLTPLLASSEYLVS----------ELSDSTL- 337

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y + +++ a l++ i+dl+ l++ e g
AJ965256_1 338 ----------LGYARNMQNGAINLNNKIDDLMNLAKGEIG 367

AJ965256_1309: domain 1 of 1, from 362 to 427: score 40.7, E = 1.2e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+ +l HELRTPLt I++++++L + + +
AJ965256_1 362 KRIYFTWALVHELRTPLTPIILASDALHS---------VAVDNKL-- 397

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ i + a l+ i++lLdl+r e g
AJ965256_1 398 ----------KSLVNNINNGASELNTRISELLDLARGEVG 427

AJ965256_1235: domain 1 of 1, from 204 to 270: score 37.7, E = 8.9e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ef++ l HEL+TPLt I++ +e+L + ++++++
AJ965256_1 204 TRIEFTRCLVHELKTPLTPILASSEALVK----------MEPAKTIQ 240

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+ + i+r a l+ in+lLdl+r+e
AJ965256_1 241 ----------GELARNIHRGACGLNVRINELLDLARLEIS 270

AJ965256_0155: domain 1 of 1, from 357 to 423: score 37.3, E = 1.1e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ l +l HE+RTPLt +++++++L + +e++ e
AJ965256_0 357 KRQAHLKALVHEIRTPLTPLLAASDALVN--------VSEKGTEL-- 393

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++i++ ae l++ i dl +l+r g
AJ965256_0 394 ----------YNLASSIREGAETLNSRIHDLIELERGKIG 423

AJ965256_0193: domain 1 of 1, from 198 to 259: score 32.1, E = 3.3e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ef++ + H+L+TPLt+I+ + +L + + + +
AJ965256_0 198 SRLEFTRIVVHDLKTPLTSIISSSGVLSN----------IAADGK-- 232

peLRledpeyreyletilreaerllrLindlLdlsr<-*
y+ + + i++++ l+ +++lLd+++
AJ965256_0 233 ---------YKALASNIYESTMNLNIRLDELLDMAQ 259


Histogram of all scores:
score obs exp (one = represents 5 sequences)
----- --- ---
-14 9 0|==
-13 44 1|*========
-12 101 33|======*==============
-11 179 172|==================================*=
-10 241 320|================================================= *
-9 260 331|==================================================== *
-8 236 247|================================================ *
-7 146 156|============================== *
-6 89 89|=================*
-5 67 49|=========*====
-4 26 26|=====*
-3 12 13|==*
-2 14 7|=*=
-1 7 3|*=
0 2 1|*
> 1 25 -|=====


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 186.6759
P(chi-square) = 9.609e-35

Total sequences searched: 1458

Whole sequence top hits:
tophits_s report:
Total hits: 21
Satisfying E cutoff: 21
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 21
Satisfying E cutoff: 21
Total memory: 29K


Acknowledgements:

This research is funded by:

Developed by: