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Classification of phyla is from NCBI page
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264 projects found  

4 accessions found for Yersinia pestis CO92  

Data for AL590842  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AL590842.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AL590842_3109 CDS_3568547-3567231 88.2 1.2e-24 1
AL590842_0250 CDS_258503-255684 86.8 2.9e-24 1
AL590842_3280 CDS_3771386-3774178 85.9 5.1e-24 1
AL590842_1188 CDS_1373592-1376465 79.3 3.8e-22 1
AL590842_3453 CDS_3965124-3962788 75.7 4.2e-21 1
AL590842_1946 CDS_2273764-2272373 69.5 2.3e-19 1
AL590842_2835 CDS_3259546-3258095 68.8 3.7e-19 1
AL590842_2921 CDS_3360876-3362420 67.1 1.1e-18 1
AL590842_0072 CDS_83613-82237 63.6 1.1e-17 1
AL590842_0023 CDS_32878-31829 62.4 2.4e-17 1
AL590842_2618 CDS_3016296-3013570 61.1 5.6e-17 1
AL590842_0872 CDS_981645-980227 58.1 4.1e-16 1
AL590842_2911 CDS_3348183-3346834 53.9 6e-15 1
AL590842_0133 CDS_149411-150763 53.2 9.7e-15 1
AL590842_3406 CDS_3918214-3919281 46.9 6.1e-13 1
AL590842_3856 CDS_4462568-4465123 40.4 4.1e-11 1
AL590842_2247 CDS_2596225-2597502 36.2 6.2e-10 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AL590842_3109 1/1 203 269 .. 1 87 [] 88.2 1.2e-24
AL590842_0250 1/1 397 462 .. 1 87 [] 86.8 2.9e-24
AL590842_3280 1/1 291 356 .. 1 87 [] 85.9 5.1e-24
AL590842_1188 1/1 479 544 .. 1 87 [] 79.3 3.8e-22
AL590842_3453 1/1 282 347 .. 1 87 [] 75.7 4.2e-21
AL590842_1946 1/1 240 306 .. 1 87 [] 69.5 2.3e-19
AL590842_2835 1/1 257 325 .. 1 87 [] 68.8 3.7e-19
AL590842_2921 1/1 280 350 .. 1 87 [] 67.1 1.1e-18
AL590842_0072 1/1 238 300 .. 1 87 [] 63.6 1.1e-17
AL590842_0023 1/1 129 194 .. 1 87 [] 62.4 2.4e-17
AL590842_2618 1/1 665 732 .. 1 87 [] 61.1 5.6e-17
AL590842_0872 1/1 255 320 .. 1 87 [] 58.1 4.1e-16
AL590842_2911 1/1 228 291 .. 1 87 [] 53.9 6e-15
AL590842_0133 1/1 233 293 .. 1 87 [] 53.2 9.7e-15
AL590842_3406 1/1 136 196 .. 1 87 [] 46.9 6.1e-13
AL590842_3856 1/1 497 559 .. 1 87 [] 40.4 4.1e-11
AL590842_2247 1/1 202 262 .. 1 87 [] 36.2 6.2e-10

Alignments of top-scoring domains:
AL590842_3109: domain 1 of 1, from 203 to 269: score 88.2, E = 1.2e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e++ + +el + r
AL590842_3 203 ARRNFFANVSHELRTPLTVLQGYLEMMHD---------QELAGPLR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l t++++++r++ L+ +lL+lsriea
AL590842_3 240 ----------DKALGTMQEQTKRMDGLVKQLLTLSRIEAA 269

AL590842_0250: domain 1 of 1, from 397 to 462: score 86.8, E = 2.9e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks+ l ++sHE+RTPL++ +g++elL++ t+l++ q
AL590842_0 397 RKSDHLTTISHEIRTPLNGALGAVELLQN---------TPLDAGQ-- 432

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ et+++++ +ll++in+lLd+srie+g
AL590842_0 433 ----------MRLAETAHQCSLSLLAIINNLLDFSRIESG 462

AL590842_3280: domain 1 of 1, from 291 to 356: score 85.9, E = 5.1e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l+ t l++ q
AL590842_3 291 IKSEFLANMSHELRTPLNGVIGFTRQTLK---------TSLTPTQ-- 326

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+yl+ti+r+a+ ll +ind+Ld+s++ea
AL590842_3 327 ----------TDYLQTIQRSANNLLCIINDVLDFSKLEAD 356

AL590842_1188: domain 1 of 1, from 479 to 544: score 79.3, E = 3.8e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
AL590842_1 479 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPQGV-- 514

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
AL590842_1 515 ----------DRLVTAMNNSSGLLLKIISDILDFSKIESE 544

AL590842_3453: domain 1 of 1, from 282 to 347: score 75.7, E = 4.2e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ tel++eq
AL590842_3 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TELDAEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+yl+ti+ +a l ++ nd+ ++ ++e
AL590842_3 318 ----------LKYLKTIHVSAITLGNIFNDIIEMDKLERR 347

AL590842_1946: domain 1 of 1, from 240 to 306: score 69.5, E = 2.3e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f a+++HELRTPLt ++g ++l l ++ ++
AL590842_1 240 QLESFNADVAHELRTPLTNLMGQTQLGLS---------RKRETHEL- 276

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++le+ l+e+er+ +++nd+L ls ++ag
AL590842_1 277 ----------EDLLESNLEELERMTSIVNDMLFLSHAQAG 306

AL590842_2835: domain 1 of 1, from 257 to 325: score 68.8, E = 3.7e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ efl+++sHEL+TPL+++r +elL +e+ ++l+ +q
AL590842_2 257 QRHEFLRHISHELKTPLASMREGTELLADEVA------GPLTQDQ-- 295

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e + ++++++++l++Li++lLd+ r a
AL590842_2 296 ----------QEVVAILDHSSRHLQQLIEQLLDYNRKLAD 325

AL590842_2921: domain 1 of 1, from 280 to 350: score 67.1, E = 1.1e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ f+ +sHEL+TPLt I +yae+L+e l+ ++ ++
AL590842_2 280 QQVSFVGQVSHELKTPLTNITLYAEMLQE-----LQPEQSVPPTAE- 320

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yle+il+e++rl+rLi+++L ++++
AL590842_2 321 ----------QRYLEVILNESQRLSRLIQNILSFTKAPKL 350

AL590842_0072: domain 1 of 1, from 238 to 300: score 63.6, E = 1.1e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++++++++sHELRTPLt +++++ l+++ + ++
AL590842_0 238 AQQRLISDISHELRTPLTRLQLATALMRR---------RHGEGKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL lsr ++
AL590842_0 274 -------------LERIEMEAQRLDSMINDLLVLSRSQHK 300

AL590842_0023: domain 1 of 1, from 129 to 194: score 62.4, E = 2.4e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
AL590842_0 129 AARDLVRGLAHEIKNPLGGLRGAAQLLAK----------ALPDPAL- 164

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
ey+++i+++a+rl++L+++lL r ++
AL590842_0 165 ----------LEYTQVIIEQADRLRNLVDRLLGPQRPGQH 194

AL590842_2618: domain 1 of 1, from 665 to 732: score 61.1, E = 5.6e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l ++ ++ +
AL590842_2 665 LRNSLLAALSHDLRTPLTVLFGQAEILTLDL-------AAEGSRH-- 702

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + i++++ + rL+n+lLd++ri++g
AL590842_2 703 ----------APQANQIRQQVLSTTRLVNNLLDMARIQSG 732

AL590842_0872: domain 1 of 1, from 255 to 320: score 58.1, E = 4.1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l HEL+ PL+aI+g+aelL+e ++ +e
AL590842_0 255 YIEQYVHTLTHELKSPLAAISGAAELLRE---------SPPPETA-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l i++++ r+++L++ +L +r+e+
AL590842_0 291 ----------QRFLINIEQQSARIQQLVDKMLVQARLESR 320

AL590842_2911: domain 1 of 1, from 228 to 291: score 53.9, E = 6e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++++l ++sHELR PL+ +++++ l ++++++ +
AL590842_2 228 AREQLLHDVSHELRSPLARLQLAIGL------------AHQNPDNV- 261

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+l++i++e+erl+++i +lL lsr+e+
AL590842_2 262 ----------DNALQRIEHESERLDKMIGELLALSRAENH 291

AL590842_0133: domain 1 of 1, from 233 to 293: score 53.2, E = 9.7e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e ++
AL590842_0 233 DRTLLMAGVSHDLRTPLTRIRLATEMMSE--------------DD-- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + e+i +++e ++++i+++ d+ r +++
AL590842_0 264 ----------AYLSESINKDIEECNAIIEQFIDYLRTGQE 293

AL590842_3406: domain 1 of 1, from 136 to 196: score 46.9, E = 6.1e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + f+a+++HELRTPL++Ir+++el+++ + e +
AL590842_3 136 QERLFTADAAHELRTPLAGIRLHLELMEK---------QGIAESK-- 171

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++ ++ l + i++lL lsr++++
AL590842_3 172 ---------------SLINRIDLLMHTIEQLLMLSRAGQN 196

AL590842_3856: domain 1 of 1, from 497 to 559: score 40.4, E = 4.1e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++ +l+H++++ L++I+g +el + + s+ +r
AL590842_3 497 AVGQLTGGLAHDFNNLLAVIIGSLELTAT----------DSSDATR- 532

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++l++aer +L ++lL +sr ++
AL590842_3 533 -------------IHRALKAAERGAQLTQRLLAFSRKQSL 559

AL590842_2247: domain 1 of 1, from 202 to 262: score 36.2, E = 6.2e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k ++ +++HELRTPL +r + + + l+e ++
AL590842_2 202 SKKLLIDGIAHELRTPLVRLRYRLAMSDN-----------LTESEQ- 236

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++++ +l++Li++lL+++r++ +
AL590842_2 237 --------------QALHHDIGQLEALIDELLTYARLDRP 262


Histogram of all scores:
score obs exp (one = represents 12 sequences)
----- --- ---
-17 1 0|=
-16 0 0|
-15 0 0|
-14 16 0|==
-13 57 2|*====
-12 189 88|=======*========
-11 349 460|============================== *
-10 644 854|====================================================== *
-9 695 882|==========================================================*
-8 707 660|======================================================*====
-7 519 416|==================================*=========
-6 290 239|===================*=====
-5 180 131|==========*====
-4 102 70|=====*===
-3 52 37|===*=
-2 25 19|=*=
-1 22 10|*=
0 5 5|*
1 5 2|*
2 3 1|*
3 1 0|=
4 3 0|=
5 0 0|
6 1 0|=
> 7 19 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 324.2434
P(chi-square) = 0

Total sequences searched: 4008

Whole sequence top hits:
tophits_s report:
Total hits: 17
Satisfying E cutoff: 17
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 17
Satisfying E cutoff: 17
Total memory: 27K


Acknowledgements:

This research is funded by:

Developed by: