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Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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106 projects found  

3 accessions found for Streptomyces coelicolor A3(2)  

Data for AL645882  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AL645882.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AL645882_5731 CDS_6279265-6284754 92.4 1.5e-25 1
AL645882_4006 CDS_4415941-4417515 89.0 1.3e-24 1
AL645882_7306 CDS_8138762-8134767 86.6 6.4e-24 1
AL645882_4891 CDS_5339528-5337921 76.9 3.6e-21 1
AL645882_5854 CDS_6426319-6428865 76.2 5.6e-21 1
AL645882_5267 CDS_5755076-5753949 75.5 9e-21 1
AL645882_1584 CDS_1709248-1708109 75.1 1.2e-20 1
AL645882_3725 CDS_4112645-4111533 72.7 5.5e-20 1
AL645882_2998 CDS_3288888-3286822 66.7 2.9e-18 1
AL645882_2130 CDS_2302365-2303729 66.5 3.1e-18 1
AL645882_7210 CDS_8036497-8038008 65.9 4.7e-18 1
AL645882_7513 CDS_8353224-8354738 65.4 6.7e-18 1
AL645882_4214 CDS_4633199-4634479 64.9 9.3e-18 1
AL645882_6351 CDS_7030354-7031664 60.7 1.4e-16 1
AL645882_5288 CDS_5777874-5776630 58.4 6.4e-16 1
AL645882_5762 CDS_6316347-6317792 54.6 7.6e-15 1
AL645882_3345 CDS_3717647-3719170 54.5 8e-15 1
AL645882_5846 CDS_6419968-6421212 53.1 2e-14 1
AL645882_4140 CDS_4573116-4571671 50.9 8.6e-14 1
AL645882_6335 CDS_7016286-7014907 50.5 1.1e-13 1
AL645882_0859 CDS_918377-916782 49.9 1.6e-13 1
AL645882_5388 CDS_5875963-5877399 47.3 9e-13 1
AL645882_3574 CDS_3967929-3966835 39.5 1.5e-10 1
AL645882_3048 CDS_3355955-3354681 39.3 1.6e-10 1
AL645882_2787 CDS_3059226-3057814 38.2 3.3e-10 1
AL645882_7055 CDS_7864480-7865931 34.7 3.4e-09 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AL645882_5731 1/1 1365 1433 .. 1 87 [] 92.4 1.5e-25
AL645882_4006 1/1 272 339 .. 1 87 [] 89.0 1.3e-24
AL645882_7306 1/1 769 837 .. 1 87 [] 86.6 6.4e-24
AL645882_4891 1/1 284 361 .. 1 87 [] 76.9 3.6e-21
AL645882_5854 1/1 613 681 .. 1 87 [] 76.2 5.6e-21
AL645882_5267 1/1 132 196 .. 1 87 [] 75.5 9e-21
AL645882_1584 1/1 149 217 .. 1 87 [] 75.1 1.2e-20
AL645882_3725 1/1 150 214 .. 1 87 [] 72.7 5.5e-20
AL645882_2998 1/1 344 411 .. 1 87 [] 66.7 2.9e-18
AL645882_2130 1/1 237 300 .. 1 87 [] 66.5 3.1e-18
AL645882_7210 1/1 264 331 .. 1 87 [] 65.9 4.7e-18
AL645882_7513 1/1 278 347 .. 1 87 [] 65.4 6.7e-18
AL645882_4214 1/1 155 221 .. 1 87 [] 64.9 9.3e-18
AL645882_6351 1/1 220 285 .. 1 87 [] 60.7 1.4e-16
AL645882_5288 1/1 217 275 .. 1 87 [] 58.4 6.4e-16
AL645882_5762 1/1 251 314 .. 1 87 [] 54.6 7.6e-15
AL645882_3345 1/1 261 319 .. 1 87 [] 54.5 8e-15
AL645882_5846 1/1 195 261 .. 1 87 [] 53.1 2e-14
AL645882_4140 1/1 247 318 .. 1 87 [] 50.9 8.6e-14
AL645882_6335 1/1 248 314 .. 1 87 [] 50.5 1.1e-13
AL645882_0859 1/1 290 358 .. 1 87 [] 49.9 1.6e-13
AL645882_5388 1/1 263 324 .. 1 87 [] 47.3 9e-13
AL645882_3574 1/1 140 204 .. 1 87 [] 39.5 1.5e-10
AL645882_3048 1/1 202 267 .. 1 87 [] 39.3 1.6e-10
AL645882_2787 1/1 227 278 .. 1 73 [. 38.2 3.3e-10
AL645882_7055 1/1 242 316 .. 1 87 [] 34.7 3.4e-09

Alignments of top-scoring domains:
AL645882_5731: domain 1 of 1, from 1365 to 1433: score 92.4, E = 1.5e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++ +a+lL +++d ++l+++q
AL645882_5 1365 YKSEFLANMSHELRTPLNSLLILAKLLADNAD------ANLTPKQ-- 1403

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+ eti+ ++ ll+Lind+Ldls+ +ag
AL645882_5 1404 ----------VEFAETIHGAGSDLLQLINDILDLSKVDAG 1433

AL645882_4006: domain 1 of 1, from 272 to 339: score 89.0, E = 1.3e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a++sHELRTPL++Irgyael ++ g++ ++++
AL645882_4 272 RVRQFVADASHELRTPLASIRGYAELTRR-------GREQVGPDT-- 309

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r +l +i++ea r+ L++dlL l+r++ag
AL645882_4 310 ----------RHALGRIESEAGRMTLLVEDLLLLARLDAG 339

AL645882_7306: domain 1 of 1, from 769 to 837: score 86.6, E = 6.4e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++ +a+lL + +l+++q
AL645882_7 769 YKSEFLANMSHELRTPLNSLLILAQLLAQ------NPSRNLTPKQ-- 807

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
ey +i++++ ll+Lind+Ldls+ eag
AL645882_7 808 ----------VEYAGIIHSAGSDLLQLINDILDLSKVEAG 837

AL645882_4891: domain 1 of 1, from 284 to 361: score 76.9, E = 3.6e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++f+a++sHELRTPLta+ + +e+L+eel+ +ag++e
AL645882_4 284 ASRRFVADMSHELRTPLTALTAVTEVLEEELE--YAGEGEGEGGS-- 326

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+dp+++ +++ + +e++rl++L+++l++ +r +ag
AL645882_4 327 -----FDPMVEPAVRLVVSETRRLNDLVENLMEVTRFDAG 361

AL645882_5854: domain 1 of 1, from 613 to 681: score 76.2, E = 5.6e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la++sH+LRTPL++I++++ L+ d ++see+r
AL645882_5 613 IRTALLAAVSHDLRTPLAGIKAAVTSLRS-------DDVAWSEEDR- 651

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+le i++ a+rl++L+ +lLd+sr+++g
AL645882_5 652 ----------AELLEGIEEGADRLDHLVGNLLDMSRLQTG 681

AL645882_5267: domain 1 of 1, from 132 to 196: score 75.5, E = 9e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ e++an+sHELRTP++++r+ +e + +++ te+++e++
AL645882_5 132 QRKELVANVSHELRTPIAGLRAVLENIVDGV-------TEADPETM- 170

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+t+l ++erl rL++ lLdlsr+++g
AL645882_5 171 --------------RTALGQTERLGRLVETLLDLSRLDNG 196

AL645882_1584: domain 1 of 1, from 149 to 217: score 75.1, E = 1.2e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ e++a+++HELR PLt+++g++ +Ll+ +++ +++q+
AL645882_1 149 SHAELIATVAHELRSPLTSVKGFTATLLA-------KWERFTDDQK- 187

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r +let++ +a+r rLi +lLd+sri++g
AL645882_1 188 ----------RLMLETVDADADRVTRLIAELLDISRIDSG 217

AL645882_3725: domain 1 of 1, from 150 to 214: score 72.7, E = 5.5e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++e++a +sH+LRTPL+++r+++e+L++ + + +++
AL645882_3 150 SRRELVAWISHDLRTPLAGLRAMSEALED---------GVAADPD-- 185

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+yl+ i+ e+erl++++ dl +lsri ag
AL645882_3 186 -----------RYLRQIRAEVERLNDMVGDLFELSRIHAG 214

AL645882_2998: domain 1 of 1, from 344 to 411: score 66.7, E = 2.9e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f++++sHELRTPLt++r++a+++ + + + ++ +
AL645882_2 344 MQRRFVSDVSHELRTPLTTVRMAADVIHD-------ARVDFDPVT-- 381

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ e + ++++r + L+ dlL++sr +ag
AL645882_2 382 ----------ARSAELLADQLDRFETLLADLLEISRFDAG 411

AL645882_2130: domain 1 of 1, from 237 to 300: score 66.5, E = 3.1e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+ ++ HELRTP+t +rg++el+ + ++e
AL645882_2 237 TQRRFVDDAGHELRTPITIVRGHLELMGD-----------DPAER-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e ++ + +e++r++r+++dlL l+++e +
AL645882_2 271 ----------EETVRLVTDELDRMSRIVEDLLLLAKAERP 300

AL645882_7210: domain 1 of 1, from 264 to 331: score 65.9, E = 4.7e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++f+a++sHELRTPL+a+++ +++L e++ + l+e++
AL645882_7 264 GARRFAADVSHELRTPLAAMSAVTDVLDEDA-------AGLDEDT-- 301

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ i e+ l +L++dl++ sr +ag
AL645882_7 302 ----------ATAVRLISTETTKLAALVDDLMEVSRFDAG 331

AL645882_7513: domain 1 of 1, from 278 to 347: score 65.4, E = 6.7e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++f+a+++HELRTPL+a+ + +e+L e++ ++ l++++
AL645882_7 278 GARRFAADVAHELRTPLAAMAAVTEVLDEDAA-----SGVLPADT-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ i +e++ l r+++dl++ sr +a
AL645882_7 318 ----------EDAVRLISEEVRTLTRMVEDLMEVSRFDAK 347

AL645882_4214: domain 1 of 1, from 155 to 221: score 64.9, E = 9.3e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+an+sHEL+TP+ a+++++e+ + ++ ++e +
AL645882_4 155 VRRDFVANVSHELKTPVGALSLLSEAVMD---------AADDPEAV- 191

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++ ea rl +L+++l dlsr ++
AL645882_4 192 ----------ERFAGRMQIEATRLTNLVQELIDLSRVQND 221

AL645882_6351: domain 1 of 1, from 220 to 285: score 60.7, E = 1.4e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+an+sH+LRTPLt++++++e+ l+ ++ ++ +
AL645882_6 220 RERDFTANASHQLRTPLTGLQLTLEAGLA---------QDDDAGT-- 255

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r +l+ +l ++rl r ++++L lsr
AL645882_6 256 ----------RPALQEALATTRRLHRTVEEVLRLSRFHGL 285

AL645882_5288: domain 1 of 1, from 217 to 275: score 58.4, E = 6.4e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++f+a+++HELRTPLt++ ++aelL
AL645882_5 217 AEQRFTADVAHELRTPLTGLHAAAELLPP------------------ 245

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +e +++ + l+ L +dlL++sr+e+g
AL645882_5 246 ----------GRPTELVRDRVAALRTLTEDLLEISRLESG 275

AL645882_5762: domain 1 of 1, from 251 to 314: score 54.6, E = 7.6e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f+a++sH+LR+PL+a+++ +elL el +e +ee
AL645882_5 251 QQRAFVADASHQLRNPLAALLLRIELLALEL-------PEGNEEI-- 288

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ e++rl r ++dlLdl+ +e+
AL645882_5 289 --------------ASVQTEGKRLARVLDDLLDLALAEHS 314

AL645882_3345: domain 1 of 1, from 261 to 319: score 54.5, E = 8e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++ +a+++HELRTP+t+++++aelL
AL645882_3 261 AERRVTADIAHELRTPVTGLLTAAELLPP------------------ 289

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +e +l+ a+ ++ L++d+L+ +r++
AL645882_3 290 ----------GRPTELVLDRAKAMRTLVEDVLEVARLDGA 319

AL645882_5846: domain 1 of 1, from 195 to 261: score 53.1, E = 2e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+ n+sHELRTPL+ r+++e+ l ++ + ++
AL645882_5 195 AQQRFVGNASHELRTPLAINRTLLEVHLS---------DPGAPVEL- 231

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +t+l er + L++ lL l+r +++
AL645882_5 232 ----------QQLGKTLLATNERSELLVEGLLLLARSDNQ 261

AL645882_4140: domain 1 of 1, from 247 to 318: score 50.9, E = 8.6e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++a++ HELRTPLt++r+++elL + +e + ++
AL645882_4 247 LQQQLIADAGHELRTPLTSLRTNIELLTR---------SEETGRPIP 284

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ R + +l +++ + l +Li dl +lsr ++g
AL645882_4 285 EADR------KALLASVKAQMTELAALIGDLQELSRPDTG 318

AL645882_6335: domain 1 of 1, from 248 to 314: score 50.5, E = 1.1e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++ lsHELRTPL+ I++ ++ ++ +++++q+
AL645882_6 248 HERQLTGELSHELRTPLSRIIAELDWWQT---------RPRTADQT- 284

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++i ++a++++ + + lLd +r +a+
AL645882_6 285 ----------HATHKVIAEAAQSMRTICDTLLDDARGGAP 314

AL645882_0859: domain 1 of 1, from 290 to 358: score 49.9, E = 1.6e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ +sH+L PL + +++lL++++ +++ ++
AL645882_0 290 ELEQFAYVASHDLQEPLRKVASFCQLLEKRY-------GDKLDDRG- 328

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+y++ + + a+r++ LindlL++sr +
AL645882_0 329 ----------RQYIDFAVDGAKRMQVLINDLLTFSRVGRL 358

AL645882_5388: domain 1 of 1, from 263 to 324: score 47.3, E = 9e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f+a++sHELR P++++r+ +e++ + ++
AL645882_5 263 RQRGFVADASHELRSPIASLRTQLEVAAA-------------HPE-- 294

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l+ + ++ rl+rL dlL l+r++ag
AL645882_5 295 ----------LLDLDGAVADTVRLQRLAADLLLLARLDAG 324

AL645882_3574: domain 1 of 1, from 140 to 204: score 39.5, E = 1.5e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+an+sHELRTPL++ ++ ++++++ d+++++ ++
AL645882_3 140 EQRRFAANASHELRTPLAVSKAILDVART--------DPHQDPGEI- 177

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ r +L + lL lsr+++
AL645882_3 178 -------------IDRLHAVNTRAIDLTEALLLLSRAGQR 204

AL645882_3048: domain 1 of 1, from 202 to 267: score 39.3, E = 1.6e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++a++sH+LRTPLta+++ +e + t+ +e
AL645882_3 202 AERRLAADASHQLRTPLTALSMRLEEITL---------TDEPETV-- 237

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e ++l+++erl + +++lL+ sr
AL645882_3 238 ----------KEEATIALSQVERLTDVVDRLLTNSRDPRS 267

AL645882_2787: domain 1 of 1, from 227 to 278: score 38.2, E = 3.3e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+e++a+lsH LRTPLt++r++a L + +++ e++
AL645882_2 227 NERELAADLSHRLRTPLTVLRLNAASLGD---------GPAAEQT-- 262

peLRledpeyreyletilreaerllr<-*
r ++e ++re++ + r
AL645882_2 263 ----------RAAVEQLEREVDTIIR 278

AL645882_7055: domain 1 of 1, from 242 to 316: score 34.7, E = 3.4e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldk...vlagdtelsee
a++ ++ +++HEL+TPLt++r+++elL + ld+++++ d++l++e
AL645882_7 242 AQRLLAEDAAHELKTPLTSLRLNVELLIR-LDRrgtL---DSALPAE 284

qrlpeLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r ++l+ + ++ l+ L+ +l dl+r +
AL645882_7 285 SR-----------TRLLNDLGAQVAELSTLVAELTDLARGDVS 316


Histogram of all scores:
score obs exp (one = represents 27 sequences)
----- --- ---
-15 1 0|=
-14 20 0|=
-13 82 5|*===
-12 316 177|======*=====
-11 746 920|============================ *
-10 1297 1708|================================================= *
-9 1559 1764|==========================================================*
-8 1340 1320|================================================*=
-7 964 832|==============================*=====
-6 596 479|=================*=====
-5 354 262|=========*====
-4 183 140|=====*=
-3 132 74|==*==
-2 61 38|=*=
-1 40 20|*=
0 24 10|*
1 11 5|*
2 6 2|*
3 2 1|*
4 1 0|=
5 2 0|=
6 0 0|
7 3 0|=
> 8 29 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 1451.7814
P(chi-square) = 0

Total sequences searched: 7825

Whole sequence top hits:
tophits_s report:
Total hits: 26
Satisfying E cutoff: 26
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 26
Satisfying E cutoff: 26
Total memory: 31K


Acknowledgements:

This research is funded by:

Developed by: