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2 accessions found for Brucella melitensis biovar Abortus 2308  

Data for AM040264  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AM040264.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
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Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AM040264_0640 CDS_629411-627060 90.3 1.6e-25 1
AM040264_1621 CDS_1565152-1568259 89.7 2.4e-25 1
AM040264_0328 CDS_328483-329799 85.6 3.5e-24 1
AM040264_2093 CDS_2027666-2029471 72.5 1.8e-20 1
AM040264_2101 CDS_2033040-2035619 71.3 4e-20 1
AM040264_0601 CDS_587749-589578 63.3 7.1e-18 1
AM040264_1141 CDS_1111587-1110484 55.3 1.4e-15 1
AM040264_0637 CDS_620156-621559 48.8 9.4e-14 1
AM040264_0346 CDS_348918-345394 45.0 1.1e-12 1
AM040264_1139 CDS_1108921-1106597 42.4 5.9e-12 1
AM040264_0132 CDS_146570-147862 40.1 2.7e-11 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AM040264_0640 1/1 543 612 .. 1 87 [] 90.3 1.6e-25
AM040264_1621 1/1 795 864 .. 1 87 [] 89.7 2.4e-25
AM040264_0328 1/1 200 267 .. 1 87 [] 85.6 3.5e-24
AM040264_2093 1/1 364 429 .. 1 87 [] 72.5 1.8e-20
AM040264_2101 1/1 627 695 .. 1 87 [] 71.3 4e-20
AM040264_0601 1/1 328 397 .. 1 87 [] 63.3 7.1e-18
AM040264_1141 1/1 122 186 .. 1 87 [] 55.3 1.4e-15
AM040264_0637 1/1 240 306 .. 1 87 [] 48.8 9.4e-14
AM040264_0346 1/1 801 866 .. 1 87 [] 45.0 1.1e-12
AM040264_1139 1/1 525 596 .. 1 87 [] 42.4 5.9e-12
AM040264_0132 1/1 209 275 .. 1 87 [] 40.1 2.7e-11

Alignments of top-scoring domains:
AM040264_0640: domain 1 of 1, from 543 to 612: score 90.3, E = 1.6e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
akseflan+sHELRTPL+aI+g++e+++++ + ++l+++
AM040264_0 543 AKSEFLANMSHELRTPLNAIIGFSEMIQAGTF------GPLGSDR-- 581

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ey++ i+ +++ ll+ ind+Ld+s+ieag
AM040264_0 582 ---------YEEYINDIHTSGNFLLNVINDILDMSKIEAG 612

AM040264_1621: domain 1 of 1, from 795 to 864: score 89.7, E = 2.4e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k+efla +sHE+RTPL+aI+g++el+ + + ++ + +
AM040264_1 795 QKTEFLARISHEIRTPLNAIIGFSELMAD------EKFGPIGNDR-- 833

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr+yl+ i r++++ l+L+ndlLd+s+ieag
AM040264_1 834 ---------YRDYLRDINRSGNHVLALVNDLLDISKIEAG 864

AM040264_0328: domain 1 of 1, from 200 to 267: score 85.6, E = 3.5e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f+an+sHELRTPL+++rg++e+L+ +++++ ++
AM040264_0 200 MRSDFIANASHELRTPLASLRGFIETLQG---------PARNDAAAR 237

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l++++++aer++rLi+dlL lsr+e
AM040264_0 238 ----------DRFLDIMQKQAERMSRLIDDLLSLSRLEMR 267

AM040264_2093: domain 1 of 1, from 364 to 429: score 72.5, E = 1.8e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + f+a++sHEL++PLt++r ++e+L ++++e r
AM040264_2 364 AIESFAADVSHELKNPLTSLRSAVETLPL----------AKTDESR- 399

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l++i+++++rl+rLi d+ d sr++a+
AM040264_2 400 ----------KRLLDVIQHDVRRLDRLITDISDASRLDAE 429

AM040264_2101: domain 1 of 1, from 627 to 695: score 71.3, E = 4e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k++f+ ++s ELR PLt I+g++elL++ + + l+e q
AM040264_2 627 IKNDFVQHVSYELRSPLTNIIGFTELLQT------PAFGSLNERQ-- 665

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
eyl+ i ++ ll ++nd+Ldl+ +ag
AM040264_2 666 ----------LEYLDYISTSSSVLLTIVNDILDLATVDAG 695

AM040264_0601: domain 1 of 1, from 328 to 397: score 63.3, E = 7.1e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+++la++sHELRTPL++I+g++++L + ++l ++ +
AM040264_0 328 GKGRLLATVSHELRTPLNSIIGFSDMLTH------EIGGKLASDRQ- 367

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
rey i++++++ll+L+n +Ld sr+e+g
AM040264_0 368 ----------REYAGLIHQSGHYLLELVNAVLDNSRLETG 397

AM040264_1141: domain 1 of 1, from 122 to 186: score 55.3, E = 1.4e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + ++++l+HE+++PL++Irg+a+lL+ s+e+
AM040264_1 122 SVTGLASMLAHEIKNPLSGIRGAAQLLEQ----------VVSDED-- 156

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r + + i +e++r+ +L++++ +s +
AM040264_1 157 ----------RALARLITEETDRIVSLVDRMEVFSDERPI 186

AM040264_0637: domain 1 of 1, from 240 to 306: score 48.8, E = 9.4e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + n++H+L+TPLt +r ae +l +e+ e++
AM040264_0 240 GLKQVSDNIAHDLKTPLTRLRNRAEEALG---------GEKVEPE-- 275

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr +le i+ e+++l r n +L +sr+eag
AM040264_0 276 ---------YRAALEDIIGESDQLIRTFNAILMISRLEAG 306

AM040264_0346: domain 1 of 1, from 801 to 866: score 45.0, E = 1.1e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k++fla++ H++ +PL+a r+y+ +L e +l+ ++
AM040264_0 801 GKTRFLAAAGHDILQPLNAARLYSTALAE----------KLGRSET- 836

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+ + i++++e ++++ +Ld+sr+++g
AM040264_0 837 ----------SEFARNIDSSLEAVEAILGMVLDISRLDTG 866

AM040264_1139: domain 1 of 1, from 525 to 596: score 42.4, E = 5.9e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + ++ ++HE+++PLt I++ ae +++++ ++ + + e
AM040264_1 525 AWADVARRIAHEIKNPLTPIQLSAERIRRRY----GKVITEDREV-- 565

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + ++ti+r++ + r+++++ ++r+ +
AM040264_1 566 ---------FDQCTDTIIRQVGDIGRMVDEFSAFARMPKP 596

AM040264_0132: domain 1 of 1, from 209 to 275: score 40.1, E = 2.7e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HEL TPL++I + ++ +++ +++++
AM040264_0 209 ALDGLAAAAAHELGTPLATIALVVKEMQR--------AHTKDPGL-- 245

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e + ++++++r+++++++l ls +++
AM040264_0 246 ----------EEDIALLHSQTQRCREILQRLTSLSSEGEE 275


Histogram of all scores:
score obs exp (one = represents 7 sequences)
----- --- ---
-15 3 0|=
-14 12 0|==
-13 34 1|*====
-12 126 45|======*===========
-11 232 237|=================================*
-10 338 439|================================================= *
-9 383 454|======================================================= *
-8 322 340|============================================== *
-7 232 214|==============================*===
-6 131 123|=================*=
-5 79 67|=========*==
-4 46 36|=====*=
-3 22 19|==*=
-2 11 10|=*
-1 8 5|*=
0 4 2|*
1 1 1|*
2 0 0|
3 1 0|=
> 4 15 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 185.2694
P(chi-square) = 8.361e-34

Total sequences searched: 2186

Whole sequence top hits:
tophits_s report:
Total hits: 11
Satisfying E cutoff: 11
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 11
Satisfying E cutoff: 11
Total memory: 25K


Acknowledgements:

This research is funded by:

Developed by: