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Classification of phyla is from NCBI page
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106 projects found  

1 accessions found for Saccharopolyspora erythraea NRRL 2338  

Data for AM420293  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AM420293.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AM420293_3409 CDS_3847895-3851875 88.1 2.3e-24 1
AM420293_5912 CDS_6837484-6836036 82.1 1.1e-22 1
AM420293_3264 CDS_3696222-3697271 76.6 4e-21 1
AM420293_0100 CDS_127314-125860 71.1 1.5e-19 1
AM420293_5177 CDS_5918828-5920186 67.2 1.9e-18 1
AM420293_1778 CDS_2000869-2001999 67.2 1.9e-18 1
AM420293_6773 CDS_7787135-7785927 66.7 2.6e-18 1
AM420293_0975 CDS_1112392-1113780 66.0 4.1e-18 1
AM420293_6261 CDS_7229322-7227580 65.4 6.1e-18 1
AM420293_4703 CDS_5354034-5355338 65.4 6.2e-18 1
AM420293_0748 CDS_852771-854270 63.9 1.6e-17 1
AM420293_5904 CDS_6826868-6824229 61.7 6.8e-17 1
AM420293_0260 CDS_302007-300493 57.5 1.1e-15 1
AM420293_2756 CDS_3092460-3091075 52.8 2.3e-14 1
AM420293_6415 CDS_7403667-7402330 46.0 1.9e-12 1
AM420293_0186 CDS_223693-222494 43.9 7.3e-12 1
AM420293_4004 CDS_4499843-4498440 42.1 2.4e-11 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AM420293_3409 1/1 878 946 .. 1 87 [] 88.1 2.3e-24
AM420293_5912 1/1 244 311 .. 1 87 [] 82.1 1.1e-22
AM420293_3264 1/1 118 185 .. 1 87 [] 76.6 4e-21
AM420293_0100 1/1 261 324 .. 1 87 [] 71.1 1.5e-19
AM420293_5177 1/1 234 301 .. 1 87 [] 67.2 1.9e-18
AM420293_1778 1/1 155 222 .. 1 87 [] 67.2 1.9e-18
AM420293_6773 1/1 145 211 .. 1 87 [] 66.7 2.6e-18
AM420293_0975 1/1 231 296 .. 1 87 [] 66.0 4.1e-18
AM420293_6261 1/1 298 365 .. 1 87 [] 65.4 6.1e-18
AM420293_4703 1/1 219 285 .. 1 87 [] 65.4 6.2e-18
AM420293_0748 1/1 250 322 .. 1 87 [] 63.9 1.6e-17
AM420293_5904 1/1 617 685 .. 1 87 [] 61.7 6.8e-17
AM420293_0260 1/1 278 342 .. 1 87 [] 57.5 1.1e-15
AM420293_2756 1/1 237 301 .. 1 87 [] 52.8 2.3e-14
AM420293_6415 1/1 222 269 .. 1 69 [. 46.0 1.9e-12
AM420293_0186 1/1 204 262 .. 1 87 [] 43.9 7.3e-12
AM420293_4004 1/1 236 300 .. 1 87 [] 42.1 2.4e-11

Alignments of top-scoring domains:
AM420293_3409: domain 1 of 1, from 878 to 946: score 88.1, E = 2.3e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ks+flan+sHELRTPL++ + +a+lL ++++ ++l+++q
AM420293_3 878 YKSDFLANMSHELRTPLNSALILAKLLADNME------GNLTPQQ-- 916

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ +ti++++ ll+Lind+Ldls+ eag
AM420293_3 917 ----------VDLAKTIHSAGTDLLQLINDVLDLSKVEAG 946

AM420293_5912: domain 1 of 1, from 244 to 311: score 82.1, E = 1.1e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPLt+Irg+ael ++ +dt++ e+
AM420293_5 244 RMRRFVADASHELRTPLTSIRGFAELYRR-------SDTHREEDV-- 281

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++ ++i+ ea r+ ++++dlL l+r++ +
AM420293_5 282 ----------RRIMSRIEGEAVRMGAMVEDLLLLARLDRE 311

AM420293_3264: domain 1 of 1, from 118 to 185: score 76.6, E = 4e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++e++a +sH+LRTPL++Ir++ae+L +++ + +ee
AM420293_3 118 SRRELVAWISHDLRTPLAGIRAMAEALSDGV-------VAGPEEV-- 155

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
ey +i+ ea+rl +++dl +lsri ag
AM420293_3 156 ----------CEYAGRIHGEAQRLAGMVDDLFELSRINAG 185

AM420293_0100: domain 1 of 1, from 261 to 324: score 71.1, E = 1.5e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+ ++sHELRTP+t +rg++elL + ++e
AM420293_0 261 TQRRFVDDASHELRTPITIVRGNLELLGD-----------DPAER-- 294

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e ++ +e++r+ r+++dlL l++++ +
AM420293_0 295 ----------EEVVRLCTDELDRMTRIVEDLLMLAKADRP 324

AM420293_5177: domain 1 of 1, from 234 to 301: score 67.2, E = 1.9e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++a++sHELRTPLt++r++++lL + + l++ qr
AM420293_5 234 AQRRLVADASHELRTPLTGLRTNIDLLAR--------AERLTPRQR- 271

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +e ++ + l L+ndl dl+r + +
AM420293_5 272 ----------FDTVEALRVKGTELTGLVNDLIDLARGDDP 301

AM420293_1778: domain 1 of 1, from 155 to 222: score 67.2, E = 1.9e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+an+sHELRTPL+++r+ +e+ l d++++e+++
AM420293_1 155 SQRRFVANASHELRTPLSVVRTELEVTLS--------DPDADEQEL- 192

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++ +++++++ r +rL++ lL l+r e
AM420293_1 193 ----------RRMADVVREATARAERLVEALLLLARTEGV 222

AM420293_6773: domain 1 of 1, from 145 to 211: score 66.7, E = 2.6e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+an+sHEL+TP+ a+ ++ae+ l+ ++ ++e++
AM420293_6 145 TRRDFVANVSHELKTPVGALALLAEAVLD---------AADDPEEV- 181

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++ +il+e+ rl L+++l lsr++
AM420293_6 182 ----------RRFSTKILHESTRLGTLVSELIALSRLQGA 211

AM420293_0975: domain 1 of 1, from 231 to 296: score 66.0, E = 4.1e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+ +++HELR+P++aIr ae++ + ++eq+
AM420293_0 231 WLRRFTGDAAHELRNPVSAIRVQAEVAVV----------HPDPEQA- 266

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+l+ i +e++rl++L++ lL l+r+e g
AM420293_0 267 ----------QEALQEIADETKRLSDLVDGLLALARAERG 296

AM420293_6261: domain 1 of 1, from 298 to 365: score 65.4, E = 6.1e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f++++sHELRTPLt++r++a++L + +++ ++
AM420293_6 298 LQRRFTSDVSHELRTPLTTVRMAADVLHA-------SREQFPPGL-- 335

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +e + +e++r ++L+ dlL++sr++ag
AM420293_6 336 ----------SRSTELLVDELDRFESLLADLLEISRLDAG 365

AM420293_4703: domain 1 of 1, from 219 to 285: score 65.4, E = 6.2e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a+++HELRTP +++r++ae+Ll +e+++e+r
AM420293_4 219 RTRRFVADAAHELRTPTAGVRAAAEALLH---------AEADPETR- 255

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++ ++ ea+r rL++dlL l+ri+ag
AM420293_4 256 ----------ERMTALLIGEARRTGRLVEDLLSLARIDAG 285

AM420293_0748: domain 1 of 1, from 250 to 322: score 63.9, E = 1.6e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++++a++ HELRTPLt++r+++elL + ++ +g ++ls+e+r
AM420293_0 250 RQRRLVADAGHELRTPLTSLRTNLELLMASAE---PGAPALSAEDR- 292

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e++ ++ ++ l++L+ dl +l+r +++
AM420293_0 293 ----------EEMFADVRAQITELSSLVGDLVELAREDTP 322

AM420293_5904: domain 1 of 1, from 617 to 685: score 61.7, E = 6.8e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +l+++ H+LRTPL++I++ ++ L++ d lsee++
AM420293_5 617 LRTALLSAVGHDLRTPLASIKASVSSLRA-------PDLRLSEEDT- 655

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+l ++++a+rl +L+++lLd sr+ +g
AM420293_5 656 ----------TELLTGVEESADRLTALVDNLLDSSRLATG 685

AM420293_0260: domain 1 of 1, from 278 to 342: score 57.5, E = 1.1e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a+++H+LRTP +++ ++a+ L+ + +e
AM420293_0 278 QQQRFVADVAHDLRTPTASLVAAADSLEH----------PDPESR-- 312

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +a+rl rL++dlL++sr ++g
AM420293_0 313 ----------SRAVALVSTQARRLARLVDDLLEISRFDSG 342

AM420293_2756: domain 1 of 1, from 237 to 301: score 52.8, E = 2.3e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f++++sH+LR+PL+a+++ ++L++ +l++e
AM420293_2 237 RQRSFVSDASHQLRNPLSALLLRQQALEM----------DLPPEL-- 271

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re ++++e++rl r +++lL l+ +e+
AM420293_2 272 ----------REDWASAQEEGRRLHRVLDELLALATAEQS 301

AM420293_6415: domain 1 of 1, from 222 to 269: score 46.0, E = 1.9e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +e++a+lsH LRTPLta+r++ae+L + +++ e++
AM420293_6 222 AEREMAADLSHRLRTPLTALRLNAEALGD---------GPAAEQT-- 257

peLRledpeyreyletilreae<-*
r ++++++re++
AM420293_6 258 ----------RVAVDRLEREVD 269

AM420293_0186: domain 1 of 1, from 204 to 262: score 43.9, E = 7.3e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++ +a+++H+LRTP++++ ++aelL
AM420293_0 204 AEQRVTADIAHDLRTPVAGLVTAAELLPP------------------ 232

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +e +++ + l+ L++d+L+ +r++a
AM420293_0 233 ----------SRGTELVRDRVAVLRTLVEDVLEVARLDAD 262

AM420293_4004: domain 1 of 1, from 236 to 300: score 42.1, E = 2.4e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++++a++sH+LR+P++a+r+ +++L++ +e +
AM420293_4 236 RQRRMVADASHQLRNPMAALRLRVDALER----------RIQPEAM- 271

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ y +t+ +e+erl++L+++lL ls ++
AM420293_4 272 ----------AGYWSTV-EEVERLEALLDRLLVLSTADDS 300


Histogram of all scores:
score obs exp (one = represents 24 sequences)
----- --- ---
-15 1 0|=
-14 28 0|==
-13 108 5|*====
-12 302 164|======*======
-11 666 853|============================ *
-10 1256 1582|===================================================== *
-9 1368 1634|========================================================= *
-8 1224 1223|==================================================*
-7 912 771|================================*=====
-6 579 443|==================*======
-5 313 243|==========*===
-4 195 130|=====*===
-3 92 68|==*=
-2 68 36|=*=
-1 34 18|*=
0 14 9|*
1 6 5|*
2 8 2|*
3 2 1|*
4 1 0|=
5 1 0|=
> 6 19 -|=


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 2385.0906
P(chi-square) = 0

Total sequences searched: 7198

Whole sequence top hits:
tophits_s report:
Total hits: 17
Satisfying E cutoff: 17
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 17
Satisfying E cutoff: 17
Total memory: 27K


Acknowledgements:

This research is funded by:

Developed by: