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Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
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Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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76 projects found  

4 accessions found for Burkholderia cenocepacia J2315  

Data for AM747721  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AM747721.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AM747721_0232 CDS_284665-281630 87.4 1.4e-24 1
AM747721_0223 CDS_258694-255662 76.2 2.1e-21 1
AM747721_2768 CDS_3116427-3118961 72.2 2.7e-20 1
AM747721_1506 CDS_1671083-1673065 71.2 5.5e-20 1
AM747721_0722 CDS_793116-794540 67.9 4.7e-19 1
AM747721_1421 CDS_1575820-1574336 67.0 8.5e-19 1
AM747721_2769 CDS_3121154-3119001 62.9 1.2e-17 1
AM747721_1387 CDS_1537081-1538505 61.0 4.2e-17 1
AM747721_0447 CDS_498588-497179 60.2 7.1e-17 1
AM747721_2179 CDS_2432651-2431521 59.3 1.3e-16 1
AM747721_2003 CDS_2213627-2212176 57.5 4.2e-16 1
AM747721_2166 CDS_2409274-2410641 54.5 3e-15 1
AM747721_0329 CDS_377465-378817 52.2 1.3e-14 1
AM747721_0382 CDS_431014-429194 50.7 3.4e-14 1
AM747721_0113 CDS_124424-123339 45.5 1.1e-12 1
AM747721_0888 CDS_975093-974314 39.1 6.6e-11 1
AM747721_0234 CDS_285989-287419 38.3 1.2e-10 1
AM747721_0623 CDS_686570-685146 30.6 1.7e-08 1
AM747721_2545 CDS_2872239-2874152 26.9 2e-07 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AM747721_0232 1/1 529 594 .. 1 87 [] 87.4 1.4e-24
AM747721_0223 1/1 525 590 .. 1 87 [] 76.2 2.1e-21
AM747721_2768 1/1 334 399 .. 1 87 [] 72.2 2.7e-20
AM747721_1506 1/1 282 347 .. 1 87 [] 71.2 5.5e-20
AM747721_0722 1/1 242 308 .. 1 87 [] 67.9 4.7e-19
AM747721_1421 1/1 234 301 .. 1 87 [] 67.0 8.5e-19
AM747721_2769 1/1 325 390 .. 1 87 [] 62.9 1.2e-17
AM747721_1387 1/1 245 310 .. 1 87 [] 61.0 4.2e-17
AM747721_0447 1/1 247 313 .. 1 87 [] 60.2 7.1e-17
AM747721_2179 1/1 161 226 .. 1 87 [] 59.3 1.3e-16
AM747721_2003 1/1 255 320 .. 1 87 [] 57.5 4.2e-16
AM747721_2166 1/1 230 295 .. 1 87 [] 54.5 3e-15
AM747721_0329 1/1 231 296 .. 1 87 [] 52.2 1.3e-14
AM747721_0382 1/1 235 300 .. 1 87 [] 50.7 3.4e-14
AM747721_0113 1/1 134 198 .. 1 87 [] 45.5 1.1e-12
AM747721_0888 1/1 28 95 .. 1 87 [] 39.1 6.6e-11
AM747721_0234 1/1 253 322 .. 1 87 [] 38.3 1.2e-10
AM747721_0623 1/1 241 298 .. 1 79 [. 30.6 1.7e-08
AM747721_2545 1/1 398 466 .. 1 87 [] 26.9 2e-07

Alignments of top-scoring domains:
AM747721_0232: domain 1 of 1, from 529 to 594: score 87.4, E = 1.4e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL+aI+g++el+ + ++l + q
AM747721_0 529 AKSAFLATMSHEIRTPLNAILGNLELIGR---------EPLAATQ-- 564

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re l+t++ ++ ll+Lind+Ldls+ieag
AM747721_0 565 ----------RERLQTVEGASSVLLDLINDILDLSKIEAG 594

AM747721_0223: domain 1 of 1, from 525 to 590: score 76.2, E = 2.1e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL+a++g++elL + ++ ++ q
AM747721_0 525 AKSTFLATISHEIRTPLNAMLGNLELLDK---------APDPSRQ-- 560

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ l+ + ++a+ ll+++n++Ld+++iea
AM747721_0 561 ----------KPRLHAVTSAARMLLDMLNNVLDMTKIEAD 590

AM747721_2768: domain 1 of 1, from 334 to 399: score 72.2, E = 2.7e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k f+a +sHE+RTP+++I+ +elL++ ++l+++q
AM747721_2 334 DKAMFFAFISHEIRTPMHTILSSLELLQR---------AKLPPKQ-- 369

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + ++e+ll L++d+Ld+sr+e+
AM747721_2 370 ----------AGRADAAVAASESLLTLLDDILDYSRLESR 399

AM747721_1506: domain 1 of 1, from 282 to 347: score 71.2, E = 5.5e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+e+la++sHELRTPL++I g +e+L++ ++ +
AM747721_1 282 LKDELLATVSHELRTPLNVIYGWVEVLRN---------ADGPGFV-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++ i+r+a++l++++ dlLd s + +g
AM747721_1 318 ----------QQAVAAIDRSARSLSHMVADLLDASSLATG 347

AM747721_0722: domain 1 of 1, from 242 to 308: score 67.9, E = 4.7e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f +nl+H++RTPLt ++++a++ l +++++++
AM747721_0 242 RLSQFSSNLAHDMRTPLTNLQAAAQVVLS---------QPRGADE-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr +e+ ++e +rl+r+i+d+L l+r e+
AM747721_0 278 ---------YRSVIESSIDEYQRLSRMIEDMLFLARSEQA 308

AM747721_1421: domain 1 of 1, from 234 to 301: score 67.0, E = 8.5e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f a+++HELRTP++ ++g ++++l+ + ++s + +
AM747721_1 234 RLEAFNADVAHELRTPISILIGQTQVALT--------SRDRSVDRM- 271

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l++ l+e erl+ +ind+L lsr + g
AM747721_1 272 ----------RQTLQSNLEEFERLRVIINDMLFLSRSDRG 301

AM747721_2769: domain 1 of 1, from 325 to 390: score 62.9, E = 1.2e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k fla +sHE+RTP+ +++ +e L++ + ls +q
AM747721_2 325 DKAMFLAFVSHEIRTPMQTVLSSLEFLQR---------SRLSVQQ-- 360

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + ++ae ll L++d+Ld+sr+e+
AM747721_2 361 ----------GGRVDAAASAAETLLTLLDDILDYSRLESR 390

AM747721_1387: domain 1 of 1, from 245 to 310: score 61.0, E = 4.2e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a+++H+L+TPL+a+++ +el+l+ ++ +
AM747721_1 245 ARRRFFADAAHQLKTPLAAVQAGVELALR---------PDEQPRA-- 280

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l+++ ++++ +++++lL lsr+++
AM747721_1 281 ----------NVHLRRANGAVRQAAKIVQQLLSLSRLDSD 310

AM747721_0447: domain 1 of 1, from 247 to 313: score 60.2, E = 7.1e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f ++l+H++RTPL+ ++ +++ l +++ ++
AM747721_0 247 RLSQFSSDLAHDMRTPLANVISSSQITLS---------RARTVDE-- 282

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ ++e+ ++e erl+r+i+++L l+r ++
AM747721_0 283 ---------YEALIESNIEECERLQRMIENMLFLARTDNA 313

AM747721_2179: domain 1 of 1, from 161 to 226: score 59.3, E = 1.3e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++ ++sHELRTPL+ +r+++e+L+e + s+ +
AM747721_2 161 AQRDLTNGISHELRTPLARVRFALEMLRE----------PGSAAE-- 195

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ +le+i +++ l++Li+ L+++r+e
AM747721_2 196 ---------YQGALESIAQDVTELEELIDMSLTYARLEYS 226

AM747721_2003: domain 1 of 1, from 255 to 320: score 57.5, E = 4.2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + +l HE++ PL+aI+g+aelL+e +++ r
AM747721_2 255 YVETYIHTLTHEMKSPLAAISGAAELLQE----------DMPVANR- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+++e i+r+a rl+++i+ lL l+ e+
AM747721_2 291 ----------RRFTENIRRQAGRLEQMIRKLLALAEVEQK 320

AM747721_2166: domain 1 of 1, from 230 to 295: score 54.5, E = 3e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ f+a+++HELRTP+ +++ ++lL++ ++++e+r
AM747721_2 230 LQRHFIADAAHELRTPIMGLSIQSQLLRR----------AATAEER- 265

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l i+ + rl +L ++lL+l+r+e
AM747721_2 266 ----------EHILAQIHAGTTRLGHLAEQLLTLARLEPD 295

AM747721_0329: domain 1 of 1, from 231 to 296: score 52.2, E = 1.3e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + f+++++HEL+TPL+a++ a+++l+ + ++ q
AM747721_0 231 RERAFTSDAAHELKTPLAALKVQAQVALT---------ARDPARQ-- 266

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++ +++ + ++r +L ++lL l+r+++
AM747721_0 267 ----------RRAMQRVVEGVDRSTHLADQLLALARLDEA 296

AM747721_0382: domain 1 of 1, from 235 to 300: score 50.7, E = 3.4e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ fl ++sHELRTPL aI g +e+Ll+ +s+
AM747721_0 235 AKNAFLGMVSHELRTPLQAICGSIEILLA---------RSQSDAN-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++++++a +l++L+ dl d+ ++++
AM747721_0 271 ----------LKTIRRLQNSALSLEALVKDLTDYIKLRST 300

AM747721_0113: domain 1 of 1, from 134 to 198: score 45.5, E = 1.1e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ + a+++HELRTP+t++rg ++ L e + ++ +
AM747721_0 134 EQTFWNAAIAHELRTPVTVLRGRLQGLAE---------GVFTPSD-- 169

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++l ++e l rLi+dl+ s +++g
AM747721_0 170 -----------ALYRSLLAQVEGLTRLIEDLRVVSLADSG 198

AM747721_0888: domain 1 of 1, from 28 to 95: score 39.1, E = 6.6e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ l+++sH+LR PL+a+ a +L+++l +++++
AM747721_0 28 LRDQALSTASHDLRSPLNAMHSWAYVLERQL-------ANADPNL-- 65

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l i+ +++ +Li+ +Ld r+e+
AM747721_0 66 ----------QRALAGIRTGIDQQVALIDGVLDAPRAETR 95

AM747721_0234: domain 1 of 1, from 253 to 322: score 38.3, E = 1.2e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+e++a+l+HEL++PLtaI ++ ++++ ld +++ + +
AM747721_0 253 TFGEMAAGLAHELNQPLTAIVSHTRAAERLLD------QPAERDSV- 292

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++l+t +a+r ++++++++ +g
AM747721_0 293 ----------RRALQTSVAQAKRAAAILERMREAVTTAHG 322

AM747721_0623: domain 1 of 1, from 241 to 298: score 30.6, E = 1.7e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a+++H++RTPL+ + + +elL + ++ +
AM747721_0 241 AMQRFIADAAHQMRTPLARLDAQIELLDG---------ESDPARH-- 276

peLRledpeyreyletilreaerllrLindlL<-*
+ l+ ++ + rL +lL
AM747721_0 277 ----------AARLDALRATSSDVGRLTGQLL 298

AM747721_2545: domain 1 of 1, from 398 to 466: score 26.9, E = 2e-07
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++a+l HEL++PL aIr++++ ++++++ ++++
AM747721_2 398 VLGQMAAGLTHELNQPLVAIRTLCDNARTFFE------RGQPAPA-- 436

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le++ + ++ + L +l +++r
AM747721_2 437 ----------LANLERVGKLVDGMAVLTGELKTFARKPDV 466


Histogram of all scores:
score obs exp (one = represents 10 sequences)
----- --- ---
-15 1 0|=
-14 6 0|=
-13 19 2|*=
-12 77 64|======*=
-11 229 332|======================= *
-10 469 617|=============================================== *
-9 575 637|==========================================================*
-8 533 477|===============================================*======
-7 376 300|=============================*========
-6 218 173|=================*====
-5 143 94|=========*=====
-4 70 50|====*==
-3 32 26|==*=
-2 13 14|=*
-1 9 7|*
0 5 3|*
1 3 2|*
2 2 1|*
> 3 27 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 146.5952
P(chi-square) = 7.386e-26

Total sequences searched: 2849

Whole sequence top hits:
tophits_s report:
Total hits: 19
Satisfying E cutoff: 19
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 19
Satisfying E cutoff: 19
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: