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Thermotogae
Classification of phyla is from NCBI page
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264 projects found  

2 accessions found for Klebsiella pneumoniae NTUH-K2044  

Data for AP006725  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AP006725.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AP006725_2137 CDS_2282440-2279747 106.3 1.1e-29 1
AP006725_3993 CDS_4222467-4225217 96.8 5.4e-27 1
AP006725_1068 CDS_1165486-1166781 91.9 1.3e-25 1
AP006725_4329 CDS_4554477-4557719 82.7 5.2e-23 1
AP006725_3512 CDS_3706846-3704006 79.4 4.6e-22 1
AP006725_4471 CDS_4692123-4689784 78.8 6.5e-22 1
AP006725_1664 CDS_1796338-1797810 78.8 6.7e-22 1
AP006725_3753 CDS_3967705-3966266 76.9 2.3e-21 1
AP006725_0071 CDS_78172-76799 66.1 2.7e-18 1
AP006725_0729 CDS_792616-794040 65.2 4.9e-18 1
AP006725_3395 CDS_3569865-3571343 63.0 2e-17 1
AP006725_0223 CDS_251289-252683 60.4 1.1e-16 1
AP006725_0026 CDS_34802-33753 60.3 1.2e-16 1
AP006725_0616 CDS_676781-678226 60.2 1.3e-16 1
AP006725_4284 CDS_4514854-4516203 59.4 2.1e-16 1
AP006725_1487 CDS_1610508-1607821 59.2 2.4e-16 1
AP006725_4626 CDS_4837484-4836129 53.8 8e-15 1
AP006725_3386 CDS_3555400-3557343 48.5 2.5e-13 1
AP006725_1571 CDS_1701451-1700354 45.8 1.5e-12 1
AP006725_2278 CDS_2433780-2432479 44.1 4.6e-12 1
AP006725_0321 CDS_364661-366946 41.0 3.5e-11 1
AP006725_2501 CDS_2639779-2637770 35.1 1.6e-09 1
AP006725_2584 CDS_2726075-2724732 31.1 2.2e-08 1
AP006725_1920 CDS_2081389-2079923 26.8 3.5e-07 2

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AP006725_2137 1/1 267 332 .. 1 87 [] 106.3 1.1e-29
AP006725_3993 1/1 292 357 .. 1 87 [] 96.8 5.4e-27
AP006725_1068 1/1 203 269 .. 1 87 [] 91.9 1.3e-25
AP006725_4329 1/1 596 662 .. 1 87 [] 82.7 5.2e-23
AP006725_3512 1/1 467 532 .. 1 87 [] 79.4 4.6e-22
AP006725_4471 1/1 282 347 .. 1 87 [] 78.8 6.5e-22
AP006725_1664 1/1 268 336 .. 1 87 [] 78.8 6.7e-22
AP006725_3753 1/1 255 323 .. 1 87 [] 76.9 2.3e-21
AP006725_0071 1/1 238 300 .. 1 87 [] 66.1 2.7e-18
AP006725_0729 1/1 255 320 .. 1 87 [] 65.2 4.9e-18
AP006725_3395 1/1 265 329 .. 1 87 [] 63.0 2e-17
AP006725_0223 1/1 241 307 .. 1 87 [] 60.4 1.1e-16
AP006725_0026 1/1 129 186 .. 1 79 [. 60.3 1.2e-16
AP006725_0616 1/1 262 328 .. 1 87 [] 60.2 1.3e-16
AP006725_4284 1/1 236 302 .. 1 87 [] 59.4 2.1e-16
AP006725_1487 1/1 663 730 .. 1 87 [] 59.2 2.4e-16
AP006725_4626 1/1 233 293 .. 1 87 [] 53.8 8e-15
AP006725_3386 1/1 427 492 .. 1 87 [] 48.5 2.5e-13
AP006725_1571 1/1 143 203 .. 1 87 [] 45.8 1.5e-12
AP006725_2278 1/1 211 271 .. 1 87 [] 44.1 4.6e-12
AP006725_0321 1/1 402 464 .. 1 87 [] 41.0 3.5e-11
AP006725_2501 1/1 448 516 .. 1 87 [] 35.1 1.6e-09
AP006725_2584 1/1 226 284 .. 1 87 [] 31.1 2.2e-08

Alignments of top-scoring domains:
AP006725_2137: domain 1 of 1, from 267 to 332: score 106.3, E = 1.1e-29
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks flan+sHE+RTP+++I+g+++l+l+ t+l++eq
AP006725_2 267 AKSAFLANMSHEIRTPMNGILGMTQLCLD---------TPLTAEQ-- 302

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
reyl+ + ++a++ll++ind+Ld+srie+g
AP006725_2 303 ----------REYLSLVMSSAQSLLHIINDILDFSRIESG 332

AP006725_3993: domain 1 of 1, from 292 to 357: score 96.8, E = 5.4e-27
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ t+l++ q
AP006725_3 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------TDLNATQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l ti+r+a+ ll++ind+Ld+s++eag
AP006725_3 328 ----------RDHLTTIERSANNLLAIINDVLDFSKLEAG 357

AP006725_1068: domain 1 of 1, from 203 to 269: score 91.9, E = 1.3e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e+++e + l +r
AP006725_1 203 ARRNFFANVSHELRTPLTVLQGYLEMMQE---------QVLEGATR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t++++++r++ L+ +lL+lsriea
AP006725_1 240 ----------EKALHTMREQTQRMEGLVKQLLTLSRIEAA 269

AP006725_4329: domain 1 of 1, from 596 to 662: score 82.7, E = 5.2e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fla++sHELRTP++aI g++elL + +el+ qr
AP006725_4 596 AKSRFLASMSHELRTPVSAIVGFLELLAK---------PELNVGQR- 632

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e++e + + a+ ll Li ++Ld+ +ie+g
AP006725_4 633 ----------KEAIELAGSTAQTLLGLIGNILDIDKIESG 662

AP006725_3512: domain 1 of 1, from 467 to 532: score 79.4, E = 4.6e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ +l+
AP006725_3 467 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KALPKGV-- 502

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
AP006725_3 503 ----------DRLVTAMNNSSSLLLKIISDILDFSKIESE 532

AP006725_4471: domain 1 of 1, from 282 to 347: score 78.8, E = 6.5e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ tel++eq
AP006725_4 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TELTSEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
AP006725_4 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

AP006725_1664: domain 1 of 1, from 268 to 336: score 78.8, E = 6.7e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ef+an+sH+LRTPLt+++gy+e+L +d+ l++e+r
AP006725_1 268 QRREFVANISHDLRTPLTSLLGYLETLTL-------KDEWLTAEER- 306

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+yl ++lr+++ ++L ++l +l+r+e+g
AP006725_1 307 ----------RQYLTIALRQGNKVRHLSQQLFELARLEHG 336

AP006725_3753: domain 1 of 1, from 255 to 323: score 76.9, E = 2.3e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +fl++lsHEL+TPL+++r +elL +++ ++l++eq
AP006725_3 255 QRHQFLRHLSHELKTPLASMREGTELLADRVA------GPLTPEQ-- 293

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e++e+++++++ l++Li++lLd+ r +a
AP006725_3 294 ----------QEIVEILDSSSRNLQKLIEQLLDYNRKQAD 323

AP006725_0071: domain 1 of 1, from 238 to 300: score 66.1, E = 2.7e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
AP006725_0 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RSGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr +a
AP006725_0 274 -------------LERIETEAHRLDSMINDLLVMSRNQAK 300

AP006725_0729: domain 1 of 1, from 255 to 320: score 65.2, E = 4.9e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + + +l HEL+ PL+aIrg+ae+L+e ++ +e
AP006725_0 255 AIENYVYDLTHELKSPLAAIRGAAEILRE---------GPPPEVA-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ il + r++ L+++lL+ +r+e+
AP006725_0 291 ----------ARFTDNILAQNTRMQLLVERLLQQARLESR 320

AP006725_3395: domain 1 of 1, from 265 to 329: score 63.0, E = 2e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++++a++sHELRTPL+++rg +e++++++ ++e
AP006725_3 265 MRRDLMADISHELRTPLAVLRGELEAIQDGV-------RRFTPES-- 302

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ e+ l +L++dl +ls ++g
AP006725_3 303 -------------IPSLQAEVATLTKLVDDLHQLSMSDEG 329

AP006725_0223: domain 1 of 1, from 241 to 307: score 60.4, E = 1.1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE+R+PL++I+g+a+ e +t + e
AP006725_0 241 ALGHLAAGVAHEIRNPLSSIKGLAKYFAE--------RTSPGGES-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++ +ea+rl+r +++lL+l r +
AP006725_0 278 ----------HQLAQVMAKEADRLNRVVSELLELVRPAHL 307

AP006725_0026: domain 1 of 1, from 129 to 186: score 60.3, E = 1.2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
AP006725_0 129 AARDLVRGLAHEIKNPLGGLRGAAQLLSK----------ALPDPAL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
AP006725_0 165 ----------TEYTKVIIEQADRLRNLVDRLL 186

AP006725_0616: domain 1 of 1, from 262 to 328: score 60.2, E = 1.3e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s f a+++HE+RTP+t + + +e++l + +s +++
AP006725_0 262 RQSNFSADIAHEIRTPITNLVTQTEIALS---------QSRSQQEL- 298

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e l + l+e r++r+++d+L l++++++
AP006725_0 299 ----------EEVLYSNLEEFSRMSRMVSDMLFLAQADNN 328

AP006725_4284: domain 1 of 1, from 236 to 302: score 59.4, E = 2.1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PL+a++ +e+++ + ++e r
AP006725_4 236 RERRFTSDAAHELRSPLAALKVQTEVAQL---------SLDDPEGR- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+ +++ ++r rL+++lL+lsr+++
AP006725_4 273 ----------EKALDQLHQGIDRATRLVDQLLTLSRLDSL 302

AP006725_1487: domain 1 of 1, from 663 to 730: score 59.2, E = 2.4e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l + ++++
AP006725_1 663 LRNSLLAALSHDLRTPLTVLFGQAEILTLDL-------ASEGSKH-- 700

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + i++ + rL+n+lLd++ri++g
AP006725_1 701 ----------APQANEIRQHVLNTTRLVNNLLDMARIQSG 730

AP006725_4626: domain 1 of 1, from 233 to 293: score 53.8, E = 8e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e ++
AP006725_4 233 DRTLLMAGVSHDLRTPLTRIRLATEMMGE---------QD------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
AP006725_4 264 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 293

AP006725_3386: domain 1 of 1, from 427 to 492: score 48.5, E = 2.5e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+ +++HE+RTPL++I++++e L+ +++s q
AP006725_3 427 HQRQFMGMVAHEFRTPLAVIQAALENLRL---------SAASTSQ-- 462

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++i r+a rl +L ++ L +r+ +
AP006725_3 463 ----------EARFDRIGRAATRLVQLTDNCLADARLASH 492

AP006725_1571: domain 1 of 1, from 143 to 203: score 45.8, E = 1.5e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + f+a+++HELRTPL+++r+++elL + + ++
AP006725_1 143 RERLFTADVAHELRTPLAGLRLHLELLAK--------VHGMG----- 176

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ +++ ++++ i++lL+l+r ++
AP006725_1 177 -------------VDPLIQRLDQMTTSISQLLQLARVGQS 203

AP006725_2278: domain 1 of 1, from 211 to 271: score 44.1, E = 4.6e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ ++ lse +
AP006725_2 211 SKKQLIDGIAHELRTPLVRLRYRLEMSEN-----------LSEAE-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
AP006725_2 245 -------------SQALNRDIGQLEALIEELLTYARLDRP 271

AP006725_0321: domain 1 of 1, from 402 to 464: score 41.0, E = 3.5e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++ +l+H++++ L++I+g +el + ++++++
AP006725_0 402 AVGQLTGGLAHDFNNLLAVIIGSLELVEP---------DARDAPR-- 437

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l+++l++aer L ++lL +sr +a
AP006725_0 438 -------------LSRALKAAERGALLTQRLLAFSRKQAL 464

AP006725_2501: domain 1 of 1, from 448 to 516: score 35.1, E = 1.6e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l+HE+++PL+a+++y+ ++ + a+++ + e+
AP006725_2 448 VVGQTMTTLAHEINQPLNALSMYLFTAGR------AIEQGQAEQA-- 486

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r l++++ ++r++++i+ l++++r +
AP006725_2 487 ----------RTTLSKAEGLINRIDAIIRSLRQFTRRAEL 516

AP006725_2584: domain 1 of 1, from 226 to 284: score 31.1, E = 2.2e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + la++sH+L TP+t +++ +e++
AP006725_2 226 ERARILAAISHDLQTPITRMKLRVEMADQ------------------ 254

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+ ++l++++ + rL+++ ++r ++
AP006725_2 255 ----------PELRGKLLQDLDNMTRLVREGIAFARTSQP 284


Histogram of all scores:
score obs exp (one = represents 17 sequences)
----- --- ---
-15 4 0|=
-14 29 0|==
-13 89 3|*=====
-12 202 114|======*=====
-11 449 593|=========================== *
-10 832 1100|================================================= *
-9 984 1136|==========================================================*
-8 864 851|==================================================*
-7 618 536|===============================*=====
-6 417 308|==================*======
-5 221 169|=========*===
-4 111 90|=====*=
-3 70 47|==*==
-2 38 25|=*=
-1 26 13|*=
0 10 6|*
1 6 3|*
2 7 1|*
3 3 0|=
> 4 26 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 290.2275
P(chi-square) = 0

Total sequences searched: 5006

Whole sequence top hits:
tophits_s report:
Total hits: 24
Satisfying E cutoff: 24
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 23
Satisfying E cutoff: 23
Total memory: 30K


Acknowledgements:

This research is funded by:

Developed by: