Acidobacteria Actinobacteria Alphaproteobacteria
Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria
Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
Search:
7 projects found  

3 accessions found for Thermus thermophilus HB8  

Data for AP008226  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AP008226.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
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Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AP008226_1143 CDS_1089513-1086622 90.8 1.1e-25 1
AP008226_1503 CDS_1431615-1433021 86.8 1.4e-24 1
AP008226_0815 CDS_780780-778279 76.8 9.7e-22 1
AP008226_1723 CDS_1618192-1619313 66.2 1e-18 1
AP008226_1592 CDS_1515326-1514022 63.9 4.5e-18 1
AP008226_1363 CDS_1300314-1301567 60.6 3.9e-17 1
AP008226_1003 CDS_948980-950197 44.8 1.1e-12 1
AP008226_0740 CDS_707113-706136 31.5 6.8e-09 1
AP008226_0144 CDS_141376-140483 30.1 1.6e-08 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AP008226_1143 1/1 736 801 .. 1 87 [] 90.8 1.1e-25
AP008226_1503 1/1 246 312 .. 1 87 [] 86.8 1.4e-24
AP008226_0815 1/1 613 679 .. 1 87 [] 76.8 9.7e-22
AP008226_1723 1/1 146 209 .. 1 87 [] 66.2 1e-18
AP008226_1592 1/1 231 292 .. 1 87 [] 63.9 4.5e-18
AP008226_1363 1/1 214 276 .. 1 87 [] 60.6 3.9e-17
AP008226_1003 1/1 198 261 .. 1 87 [] 44.8 1.1e-12
AP008226_0740 1/1 116 183 .. 1 87 [] 31.5 6.8e-09
AP008226_0144 1/1 99 159 .. 1 87 [] 30.1 1.6e-08

Alignments of top-scoring domains:
AP008226_1143: domain 1 of 1, from 736 to 801: score 90.8, E = 1.1e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+efla++sHELRTPL+aI+g+aelL+ ++l++e
AP008226_1 736 LKGEFLAAVSHELRTPLAAILGLAELLRQ---------EPLPPEA-- 771

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e +e il++a rl +++++lLd sr+eag
AP008226_1 772 ----------QESVELILESAFRLKNMVDNLLDTSRLEAG 801

AP008226_1503: domain 1 of 1, from 246 to 312: score 86.8, E = 1.4e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++fl ++sHELRTP+taI+g++ Ll+ +t+l+e q
AP008226_1 246 AQTRFLQDASHELRTPITAILGHVGYLLR--------RTPLTEAQ-- 282

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re le+++reaer+ +L++dlLdls+ +a
AP008226_1 283 ----------RESLEVVKREAERMGKLVSDLLDLSQSGAW 312

AP008226_0815: domain 1 of 1, from 613 to 679: score 76.8, E = 9.7e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+efla++sHEL+TPLta+r++ae+L +e +ee+r
AP008226_0 613 LKDEFLATVSHELKTPLTAVRALAEILAQ---------EEVGEEER- 649

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+++ + +ea rl+rL++++L ++r+ea
AP008226_0 650 ----------RRFTALLAQEAARLSRLVEEILAYTRLEAR 679

AP008226_1723: domain 1 of 1, from 146 to 209: score 66.2, E = 1e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ e++ +++HELRTPL+a++gyae L + + ls e++
AP008226_1 146 TRAELIGTVAHELRTPLAALQGYAEGLID---------GVLSKEKA- 182

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e ilre++ ++rL++dl sr ea
AP008226_1 183 -------------AEGILREVKAMRRLVEDLSLVSRVEAK 209

AP008226_1592: domain 1 of 1, from 231 to 292: score 63.9, E = 4.5e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++f++++sHELRTPLta++gy+e+L++ +
AP008226_1 231 AARRFARHASHELRTPLTALKGYLEVLRR-------------KNE-- 262

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++le +lrea r+++L+ lL lsr+ea
AP008226_1 263 ----------PRALEGALREAGRMEALLAGLLRLSRLEAL 292

AP008226_1363: domain 1 of 1, from 214 to 276: score 60.6, E = 3.9e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + fla +sHELRTPLt+++g+++ L + +++ e
AP008226_1 214 RERAFLAEASHELRTPLTVLLGHLDRLGR---------NPMDLEA-- 249

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l+t++ aer++rL++dlL l+r e +
AP008226_1 250 -------------LRTARATAERMRRLVEDLLALARGEVE 276

AP008226_1003: domain 1 of 1, from 198 to 261: score 44.8, E = 1.1e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +f+++++HELRTP++a ++ +e+++ ++ +
AP008226_1 198 REKRFTRDAAHELRTPVAAALAQLEAAEGGY-----------LSE-- 231

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+l+ ++e+ r+ rL++ lL l+r +
AP008226_1 232 ----------GEALQATKEELLRMKRLVEALLVLAREGRV 261

AP008226_0740: domain 1 of 1, from 116 to 183: score 31.5, E = 6.8e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ + a+l+H+L+TPL + + +++ L++ ++l+ e r
AP008226_0 116 AREALYAALAHDLKTPLLSALRLLDYLER--------ADDLGKERR- 153

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+l+ +++e+ r rL ++lL l+r+ea
AP008226_0 154 ----------VALLRALREELARGHRLTENLLALARLEAR 183

AP008226_0144: domain 1 of 1, from 99 to 159: score 30.1, E = 1.6e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +e a l+HE+RTPL+++ ++ +L +++ +
AP008226_0 99 EAEEAGALLAHEFRTPLAGMAVLLRALAP-----------KDPRE-- 132

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l+ +++e+ rl rL++ l + ++ g
AP008226_0 133 ----------AQVLDLLKKEVARLTRLVESL---AHLRPG 159


Histogram of all scores:
score obs exp (one = represents 7 sequences)
----- --- ---
-15 1 0|=
-14 5 0|=
-13 26 1|*===
-12 73 45|======*====
-11 165 233|======================== *
-10 322 433|============================================== *
-9 382 448|======================================================= *
-8 310 335|============================================= *
-7 250 211|==============================*=====
-6 184 121|=================*=========
-5 105 66|=========*=====
-4 67 35|====*=====
-3 25 18|==*=
-2 22 9|=*==
-1 9 5|*=
0 7 2|*
1 5 1|*
> 2 15 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 185.9804
P(chi-square) = 5.96e-34

Total sequences searched: 1973

Whole sequence top hits:
tophits_s report:
Total hits: 9
Satisfying E cutoff: 9
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 9
Satisfying E cutoff: 9
Total memory: 24K


Acknowledgements:

This research is funded by:

Developed by: