Acidobacteria Actinobacteria Alphaproteobacteria
Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria
Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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264 projects found  

4 accessions found for Sodalis glossinidius str. 'morsitans'  

Data for AP008232  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AP008232.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AP008232_0508 CDS_890027-887250 98.8 6.9e-28 1
AP008232_1581 CDS_2714748-2711872 78.1 5.1e-22 1
AP008232_1280 CDS_2154424-2151641 73.1 1.4e-20 1
AP008232_0220 CDS_402889-405315 71.7 3.3e-20 1
AP008232_2181 CDS_3797933-3799306 64.0 5e-18 1
AP008232_2231 CDS_3884374-3885423 60.3 5.5e-17 1
AP008232_2318 CDS_3982780-3981398 54.8 2.1e-15 1
AP008232_0960 CDS_1582530-1583636 46.3 5.3e-13 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AP008232_0508 1/1 293 358 .. 1 87 [] 98.8 6.9e-28
AP008232_1581 1/1 472 537 .. 1 87 [] 78.1 5.1e-22
AP008232_1280 1/1 398 463 .. 1 87 [] 73.1 1.4e-20
AP008232_0220 1/1 282 347 .. 1 87 [] 71.7 3.3e-20
AP008232_2181 1/1 238 300 .. 1 87 [] 64.0 5e-18
AP008232_2231 1/1 129 186 .. 1 79 [. 60.3 5.5e-17
AP008232_2318 1/1 233 293 .. 1 87 [] 54.8 2.1e-15
AP008232_0960 1/1 150 210 .. 1 87 [] 46.3 5.3e-13

Alignments of top-scoring domains:
AP008232_0508: domain 1 of 1, from 293 to 358: score 98.8, E = 6.9e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ks+flan+sHELRTPL++++g++ l+ t+ls+ q
AP008232_0 293 IKSKFLANMSHELRTPLNGVIGFTRQTLK---------TPLSPTQ-- 328

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+yl+ti+r++++ll++ind+Ld+s++eag
AP008232_0 329 ----------RDYLQTIERSGNHLLSIINDVLDFSKLEAG 358

AP008232_1581: domain 1 of 1, from 472 to 537: score 78.1, E = 5.1e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHELRTPL +I+g+++lL++ +l++
AP008232_1 472 AKSMFLATVSHELRTPLYGIIGNLDLLKT---------KALPDGV-- 507

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
AP008232_1 508 ----------DRLVMAMSNSSALLLNIISDILDFSKIESE 537

AP008232_1280: domain 1 of 1, from 398 to 463: score 73.1, E = 1.4e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks l ++sHELRTPL++ +g++elL++ t+l+++q
AP008232_1 398 RKSSHLTTISHELRTPLSGSLGALELLQM---------TTLTDKQ-- 433

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ +t+++++ +ll++in+lLd+srie+g
AP008232_1 434 ----------FQLADTARQCVFSLLSIINNLLDFSRIESG 463

AP008232_0220: domain 1 of 1, from 282 to 347: score 71.7, E = 3.3e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k+ f++++sHELRTPL++I g++ +Ll+ t l+eeq
AP008232_0 282 EKTTFISTISHELRTPLNGIVGLSRILLD---------TQLTEEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ yl+ti+ +a l + nd+ ++ ++e
AP008232_0 318 ----------HNYLKTIHVSAVTLGYIFNDIIEMDKLERR 347

AP008232_2181: domain 1 of 1, from 238 to 300: score 64.0, E = 5e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++++l+++sHELRTPLt +++++ l+++ + +
AP008232_2 238 AQQRLLSDISHELRTPLTRLQLATALMRR---------RHGEGHE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l +i+ ea+rl+++indlL lsr ++
AP008232_2 274 -------------LTRIETEAQRLDSMINDLLVLSRNQHK 300

AP008232_2231: domain 1 of 1, from 129 to 186: score 60.3, E = 5.5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
AP008232_2 129 AARDLVRGLAHEIKNPLGGLRGAAQLLAK----------ALPDPAL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
AP008232_2 165 ----------TEYTKVIIEQADRLRNLVDRLL 186

AP008232_2318: domain 1 of 1, from 233 to 293: score 54.8, E = 2.1e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ + e+
AP008232_2 233 DRTLLMAGVSHDLRTPLTRIRLATEMMSA--------------ED-- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
AP008232_2 264 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 293

AP008232_0960: domain 1 of 1, from 150 to 210: score 46.3, E = 5.3e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a+++HELRTPL++Ir+++el ++ + + +
AP008232_0 150 QDRQFTADVAHELRTPLAGIRLHLELHEK--------QHQIDCQP-- 186

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ ++ + +++lL l+ri++
AP008232_0 187 ----------------LIERVDNMAFTVEQLLMLARIRND 210


Histogram of all scores:
score obs exp (one = represents 8 sequences)
----- --- ---
-14 4 0|=
-13 20 1|*==
-12 76 55|======*===
-11 270 288|================================== *
-10 409 534|==================================================== *
-9 457 552|==========================================================*
-8 447 413|===================================================*====
-7 297 260|================================*=====
-6 203 149|==================*=======
-5 118 82|==========*====
-4 58 44|=====*==
-3 28 23|==*=
-2 13 12|=*
-1 13 6|*=
0 0 3|*
1 3 1|*
2 1 0|=
3 3 0|=
4 1 0|=
> 5 11 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 109.0829
P(chi-square) = 2.793e-18

Total sequences searched: 2432

Whole sequence top hits:
tophits_s report:
Total hits: 8
Satisfying E cutoff: 8
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 8
Satisfying E cutoff: 8
Total memory: 24K


Acknowledgements:

This research is funded by:

Developed by: