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Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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264 projects found  

7 accessions found for Escherichia coli SE11  

Data for AP009240  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AP009240.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AP009240_3044 CDS_3153991-3156747 100.1 5.7e-28 1
AP009240_0420 CDS_459574-460869 91.0 2.3e-25 1
AP009240_2667 CDS_2752482-2756075 81.6 1e-22 1
AP009240_1055 CDS_1139484-1136770 80.7 1.8e-22 1
AP009240_2486 CDS_2572810-2569961 80.6 2e-22 1
AP009240_3494 CDS_3623113-3620777 78.9 6e-22 1
AP009240_2844 CDS_2949880-2948453 75.4 5.9e-21 1
AP009240_2351 CDS_2418093-2419496 69.8 2.3e-19 1
AP009240_4200 CDS_4366474-4365101 66.6 1.8e-18 1
AP009240_4675 CDS_4882559-4883983 62.4 2.7e-17 1
AP009240_4292 CDS_4471497-4472873 61.5 5e-17 1
AP009240_0634 CDS_680957-679509 61.0 7e-17 1
AP009240_4152 CDS_4316637-4315588 59.7 1.7e-16 1
AP009240_3307 CDS_3434591-3435940 59.6 1.7e-16 1
AP009240_0755 CDS_808251-805567 59.6 1.7e-16 1
AP009240_3669 CDS_3784457-3783105 55.0 3.5e-15 1
AP009240_2197 CDS_2256091-2254733 52.3 2e-14 1
AP009240_4410 CDS_4604049-4602958 45.0 2.4e-12 1
AP009240_1730 CDS_1816385-1817686 42.4 1.3e-11 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AP009240_3044 1/1 292 357 .. 1 87 [] 100.1 5.7e-28
AP009240_0420 1/1 203 269 .. 1 87 [] 91.0 2.3e-25
AP009240_2667 1/1 711 777 .. 1 87 [] 81.6 1e-22
AP009240_1055 1/1 433 498 .. 1 87 [] 80.7 1.8e-22
AP009240_2486 1/1 469 534 .. 1 87 [] 80.6 2e-22
AP009240_3494 1/1 282 347 .. 1 87 [] 78.9 6e-22
AP009240_2844 1/1 249 317 .. 1 87 [] 75.4 5.9e-21
AP009240_2351 1/1 240 304 .. 1 87 [] 69.8 2.3e-19
AP009240_4200 1/1 238 300 .. 1 87 [] 66.6 1.8e-18
AP009240_4675 1/1 255 320 .. 1 87 [] 62.4 2.7e-17
AP009240_4292 1/1 237 303 .. 1 87 [] 61.5 5e-17
AP009240_0634 1/1 261 327 .. 1 87 [] 61.0 7e-17
AP009240_4152 1/1 129 186 .. 1 79 [. 59.7 1.7e-16
AP009240_3307 1/1 236 302 .. 1 87 [] 59.6 1.7e-16
AP009240_0755 1/1 663 730 .. 1 87 [] 59.6 1.7e-16
AP009240_3669 1/1 233 293 .. 1 87 [] 55.0 3.5e-15
AP009240_2197 1/1 235 301 .. 1 87 [] 52.3 2e-14
AP009240_4410 1/1 142 202 .. 1 87 [] 45.0 2.4e-12
AP009240_1730 1/1 211 271 .. 1 87 [] 42.4 1.3e-11

Alignments of top-scoring domains:
AP009240_3044: domain 1 of 1, from 292 to 357: score 100.1, E = 5.7e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ tel++ q
AP009240_3 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------TELTPTQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ti+r+a+ ll++ind+Ld+s++eag
AP009240_3 328 ----------RDHLNTIERSANNLLAIINDVLDFSKLEAG 357

AP009240_0420: domain 1 of 1, from 203 to 269: score 91.0, E = 2.3e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e++ e ++l r
AP009240_0 203 ARRNFFANVSHELRTPLTVLQGYLEMMDE---------QPLEGAVR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t++++++r++ L+ +lL+ls+iea
AP009240_0 240 ----------EKALHTMREQTQRMEGLVKQLLTLSKIEAA 269

AP009240_2667: domain 1 of 1, from 711 to 777: score 81.6, E = 1e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fla++sHE+RTP+++I+g++elL + ls eqr
AP009240_2 711 AKSQFLATMSHEIRTPISSIMGFLELLSG---------SGLSKEQR- 747

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+++ ++ +++ll Li ++Ld +ie+g
AP009240_2 748 ----------VEAISLAYATGQSLLGLIGEILDVDKIESG 777

AP009240_1055: domain 1 of 1, from 433 to 498: score 80.7, E = 1.8e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL +I+g+a+lL + ++ q
AP009240_1 433 AKSAFLAAMSHEIRTPLYGILGTAQLLAD---------NPALNAQ-- 468

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ i +++e+ll ++nd+Ld+s ieag
AP009240_1 469 ----------RDDLRAITDSGESLLTILNDILDYSAIEAG 498

AP009240_2486: domain 1 of 1, from 469 to 534: score 80.6, E = 2e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
AP009240_2 469 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPKGV-- 504

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
AP009240_2 505 ----------DRLVTAMNNSSSLLLKIISDILDFSKIESE 534

AP009240_3494: domain 1 of 1, from 282 to 347: score 78.9, E = 6e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ tel++eq
AP009240_3 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TELTAEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
AP009240_3 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

AP009240_2844: domain 1 of 1, from 249 to 317: score 75.4, E = 5.9e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +fl++lsHEL+TPL+++r +elL +++ ++l++eq
AP009240_2 249 QRHQFLRHLSHELKTPLASMREGTELLADQV------VGPLTPEQ-- 287

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e +++++++++ l++Li++lLd+ r +a
AP009240_2 288 ----------KEVVSILDSSSRNLQKLIEQLLDYNRKQAD 317

AP009240_2351: domain 1 of 1, from 240 to 304: score 69.8, E = 2.3e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPL+++rg +e++++++ + ++e+
AP009240_2 240 MRRDFMADISHELRTPLAVLRGELEAIQDGV-------RKFTPET-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ e+ l +L++dl +ls ++g
AP009240_2 278 -------------VASLQAEVGTLTKLVDDLHQLSMSDEG 304

AP009240_4200: domain 1 of 1, from 238 to 300: score 66.6, E = 1.8e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
AP009240_4 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RSGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr ++
AP009240_4 274 -------------LERIETEAQRLDSMINDLLVMSRNQQK 300

AP009240_4675: domain 1 of 1, from 255 to 320: score 62.4, E = 2.7e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l HEL+ PL+aIrg+ae+L+e ++ +e
AP009240_4 255 YIEQYVYALTHELKSPLAAIRGAAEILRE---------GPPPEVV-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ il + r+++L++ lL +r+e+
AP009240_4 291 ----------ARFTDNILTQNARMQALVETLLRQARLENR 320

AP009240_4292: domain 1 of 1, from 237 to 303: score 61.5, E = 5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE+R+PL++I+g+a+ e +++++ e
AP009240_4 237 ALGHLAAGVAHEIRNPLSSIKGLAKYFAE--------RAPAGGEA-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++ +ea+rl+r +++lL+l + +
AP009240_4 274 ----------HQLAQVMAKEADRLNRVVSELLELVKPTHL 303

AP009240_0634: domain 1 of 1, from 261 to 327: score 61.0, E = 7e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s f a+++HE+RTP+t +++ +e++l + +s +++
AP009240_0 261 RQSNFSADIAHEIRTPITNLITQTEIALS---------QSRSQKEL- 297

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l + l+e+ r+ ++++d+L l++++++
AP009240_0 298 ----------EDVLYSNLEELTRMAKMVSDMLFLAQADNN 327

AP009240_4152: domain 1 of 1, from 129 to 186: score 59.7, E = 1.7e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
AP009240_4 129 AARDLVRGLAHEIKNPLGGLRGAAQLLSK----------ALPDPSL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
AP009240_4 165 ----------LEYTKVIIEQADRLRNLVDRLL 186

AP009240_3307: domain 1 of 1, from 236 to 302: score 59.6, E = 1.7e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PLta++ +e+++ ++ +++ r
AP009240_3 236 RERRFTSDAAHELRSPLTALKVQTEVAQL---------SDDDPQAR- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l ++ ++r rL+++lL+lsr+++
AP009240_3 273 ----------KKALLQLHYGIDRATRLVDQLLTLSRLDSL 302

AP009240_0755: domain 1 of 1, from 663 to 730: score 59.6, E = 1.7e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l + ++++
AP009240_0 663 IRNALLAALSHDLRTPLTVLFGQAEILTLDL-------ASEGSPH-- 700

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + i++ + rL+n+lLd++ri++g
AP009240_0 701 ----------ARQASEIRQHVLNTTRLVNNLLDMARIQSG 730

AP009240_3669: domain 1 of 1, from 233 to 293: score 55.0, E = 3.5e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e ++
AP009240_3 233 DRTLLMAGVSHDLRTPLTRIRLATEMMSE---------QD------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
AP009240_3 264 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 293

AP009240_2197: domain 1 of 1, from 235 to 301: score 52.3, E = 2e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f+ +l+HELRTP++a++g ++ l +++s +
AP009240_2 235 RLSQFADDLAHELRTPINALLGQNQVTLS---------QTRSIAE-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y++ + ++e+e ++rL +++L l+r++ +
AP009240_2 271 ---------YQKTIAGNIEELENISRLTENILFLARADKN 301

AP009240_4410: domain 1 of 1, from 142 to 202: score 45.0, E = 2.4e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+++r+++elL + t+
AP009240_4 142 NERLFTADVAHELRTPLAGVRLHLELLAK---------TH------- 172

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + ++++ + +++lL+l+r+++
AP009240_4 173 ----------HIDVAPLVARLDQMMESVSQLLQLARAGQS 202

AP009240_1730: domain 1 of 1, from 211 to 271: score 42.4, E = 1.3e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ + ls+ +
AP009240_1 211 SKKQLIDGIAHELRTPLVRLRYRLEMSDN-----------LSAAE-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
AP009240_1 245 -------------SQALNRDISQLEALIEELLTYARLDRP 271


Histogram of all scores:
score obs exp (one = represents 15 sequences)
----- --- ---
-15 5 0|=
-14 30 0|==
-13 87 3|*=====
-12 253 106|=======*=========
-11 497 554|================================== *
-10 797 1028|====================================================== *
-9 858 1062|==========================================================*
-8 757 795|=================================================== *
-7 537 501|=================================*==
-6 377 288|===================*======
-5 208 158|==========*===
-4 93 84|=====*=
-3 55 44|==*=
-2 30 23|=*
-1 38 12|*==
0 15 6|*
1 7 3|*
2 12 1|*
3 2 0|=
4 0 0|
> 5 21 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 414.7385
P(chi-square) = 0

Total sequences searched: 4679

Whole sequence top hits:
tophits_s report:
Total hits: 19
Satisfying E cutoff: 19
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 19
Satisfying E cutoff: 19
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: