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Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
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Firmicutes Fusobacteria Gammaproteobacteria
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Thermotogae
Classification of phyla is from NCBI page
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2 accessions found for   

Data for AP009378  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AP009378.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AP009378_2577 CDS_2803638-2806394 100.1 5.2e-28 1
AP009378_0360 CDS_406734-408029 91.0 2.1e-25 1
AP009378_2240 CDS_2425596-2429189 81.6 9.3e-23 1
AP009378_0900 CDS_1005743-1003041 80.7 1.6e-22 1
AP009378_2100 CDS_2266859-2264058 80.6 1.8e-22 1
AP009378_3042 CDS_3313639-3311303 78.9 5.6e-22 1
AP009378_2101 CDS_2267074-2268900 77.9 1e-21 1
AP009378_2395 CDS_2612627-2611200 75.4 5.4e-21 1
AP009378_1966 CDS_2112258-2113661 70.4 1.4e-19 1
AP009378_3772 CDS_4093372-4091999 66.6 1.7e-18 1
AP009378_4334 CDS_4712382-4713806 62.4 2.5e-17 1
AP009378_3857 CDS_4194189-4195565 61.5 4.7e-17 1
AP009378_0500 CDS_558263-556821 61.0 6.5e-17 1
AP009378_2860 CDS_3127039-3128388 60.7 8.1e-17 1
AP009378_3722 CDS_4037835-4036786 59.7 1.6e-16 1
AP009378_0630 CDS_701621-698937 59.6 1.6e-16 1
AP009378_3226 CDS_3490850-3489498 55.0 3.2e-15 1
AP009378_1817 CDS_1925317-1923959 52.3 1.8e-14 1
AP009378_3992 CDS_4351138-4350047 45.0 2.2e-12 1
AP009378_1470 CDS_1583813-1585114 42.4 1.2e-11 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AP009378_2577 1/1 292 357 .. 1 87 [] 100.1 5.2e-28
AP009378_0360 1/1 203 269 .. 1 87 [] 91.0 2.1e-25
AP009378_2240 1/1 711 777 .. 1 87 [] 81.6 9.3e-23
AP009378_0900 1/1 433 498 .. 1 87 [] 80.7 1.6e-22
AP009378_2100 1/1 453 518 .. 1 87 [] 80.6 1.8e-22
AP009378_3042 1/1 282 347 .. 1 87 [] 78.9 5.6e-22
AP009378_2101 1/1 388 453 .. 1 87 [] 77.9 1e-21
AP009378_2395 1/1 249 317 .. 1 87 [] 75.4 5.4e-21
AP009378_1966 1/1 240 304 .. 1 87 [] 70.4 1.4e-19
AP009378_3772 1/1 238 300 .. 1 87 [] 66.6 1.7e-18
AP009378_4334 1/1 255 320 .. 1 87 [] 62.4 2.5e-17
AP009378_3857 1/1 237 303 .. 1 87 [] 61.5 4.7e-17
AP009378_0500 1/1 261 327 .. 1 87 [] 61.0 6.5e-17
AP009378_2860 1/1 236 302 .. 1 87 [] 60.7 8.1e-17
AP009378_3722 1/1 129 186 .. 1 79 [. 59.7 1.6e-16
AP009378_0630 1/1 663 730 .. 1 87 [] 59.6 1.6e-16
AP009378_3226 1/1 233 293 .. 1 87 [] 55.0 3.2e-15
AP009378_1817 1/1 235 301 .. 1 87 [] 52.3 1.8e-14
AP009378_3992 1/1 142 202 .. 1 87 [] 45.0 2.2e-12
AP009378_1470 1/1 211 271 .. 1 87 [] 42.4 1.2e-11

Alignments of top-scoring domains:
AP009378_2577: domain 1 of 1, from 292 to 357: score 100.1, E = 5.2e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ tel++ q
AP009378_2 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------TELTPTQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ti+r+a+ ll++ind+Ld+s++eag
AP009378_2 328 ----------RDHLNTIERSANNLLAIINDVLDFSKLEAG 357

AP009378_0360: domain 1 of 1, from 203 to 269: score 91.0, E = 2.1e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e++ e ++l r
AP009378_0 203 ARRNFFANVSHELRTPLTVLQGYLEMMDE---------QPLEGAVR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t++++++r++ L+ +lL+ls+iea
AP009378_0 240 ----------EKALHTMREQTQRMEGLVKQLLTLSKIEAA 269

AP009378_2240: domain 1 of 1, from 711 to 777: score 81.6, E = 9.3e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fla++sHE+RTP+++I+g++elL + ls eqr
AP009378_2 711 AKSQFLATMSHEIRTPISSIMGFLELLSG---------SGLSKEQR- 747

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+++ ++ +++ll Li ++Ld +ie+g
AP009378_2 748 ----------VEAISLAYATGQSLLGLIGEILDVDKIESG 777

AP009378_0900: domain 1 of 1, from 433 to 498: score 80.7, E = 1.6e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL +I+g+a+lL + ++ q
AP009378_0 433 AKSAFLAAMSHEIRTPLYGILGTAQLLAD---------NPALNAQ-- 468

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ i +++e+ll ++nd+Ld+s ieag
AP009378_0 469 ----------RDDLRAITDSGESLLTILNDILDYSAIEAG 498

AP009378_2100: domain 1 of 1, from 453 to 518: score 80.6, E = 1.8e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
AP009378_2 453 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPKGV-- 488

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
AP009378_2 489 ----------DRLVTAMNNSSSLLLKIISDILDFSKIESE 518

AP009378_3042: domain 1 of 1, from 282 to 347: score 78.9, E = 5.6e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ tel++eq
AP009378_3 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TELTAEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
AP009378_3 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

AP009378_2101: domain 1 of 1, from 388 to 453: score 77.9, E = 1e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++a+++HE R+PLtaIrgy+++L+ +++++ +
AP009378_2 388 TLGELMAGVAHEVRNPLTAIRGYVQILRQ---------QTRDPIH-- 423

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+eyl+++l+e++++++ i++lL++sr ++
AP009378_2 424 ----------QEYLSVVLKEIDSINKVIQQLLEFSRPRHS 453

AP009378_2395: domain 1 of 1, from 249 to 317: score 75.4, E = 5.4e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +fl++lsHEL+TPL+++r +elL +++ ++l++eq
AP009378_2 249 QRHQFLRHLSHELKTPLASMREGTELLADQV------VGPLTPEQ-- 287

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e +++++++++ l++Li++lLd+ r +a
AP009378_2 288 ----------KEVVSILDSSSRNLQKLIEQLLDYNRKQAD 317

AP009378_1966: domain 1 of 1, from 240 to 304: score 70.4, E = 1.4e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPL+++rg +e++++++ + ++e+
AP009378_1 240 MRRDFMADISHELRTPLAVLRGELEAIQDGV-------RKFTPET-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l +++ e+ l +L++dl +ls ++g
AP009378_1 278 -------------LASLQAEVGTLTKLVDDLHQLSMSDEG 304

AP009378_3772: domain 1 of 1, from 238 to 300: score 66.6, E = 1.7e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
AP009378_3 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RSGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr ++
AP009378_3 274 -------------LERIETEAQRLDSMINDLLVMSRNQQK 300

AP009378_4334: domain 1 of 1, from 255 to 320: score 62.4, E = 2.5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l HEL+ PL+aIrg+ae+L+e ++ +e
AP009378_4 255 YIEQYVYALTHELKSPLAAIRGAAEILRE---------GPPPEVV-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ il + r+++L++ lL +r+e+
AP009378_4 291 ----------ARFTDNILTQNARMQALVETLLRQARLENR 320

AP009378_3857: domain 1 of 1, from 237 to 303: score 61.5, E = 4.7e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE+R+PL++I+g+a+ e +++++ e
AP009378_3 237 ALGHLAAGVAHEIRNPLSSIKGLAKYFAE--------RAPAGGEA-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++ +ea+rl+r +++lL+l + +
AP009378_3 274 ----------HQLAQVMAKEADRLNRVVSELLELVKPTHL 303

AP009378_0500: domain 1 of 1, from 261 to 327: score 61.0, E = 6.5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s f a+++HE+RTP+t +++ +e++l + +s +++
AP009378_0 261 RQSNFSADIAHEIRTPITNLITQTEIALS---------QSRSQKEL- 297

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l + l+e+ r+ ++++d+L l++++++
AP009378_0 298 ----------EDVLYSNLEELTRMAKMVSDMLFLAQADNN 327

AP009378_2860: domain 1 of 1, from 236 to 302: score 60.7, E = 8.1e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PLta++ +e+++ ++ +++ r
AP009378_2 236 RERRFTSDAAHELRSPLTALKVQTEVAQL---------SDDDPQAR- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l +++ ++r rL+++lL+lsr+++
AP009378_2 273 ----------KKALLQLHSGIDRATRLVDQLLTLSRLDSL 302

AP009378_3722: domain 1 of 1, from 129 to 186: score 59.7, E = 1.6e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
AP009378_3 129 AARDLVRGLAHEIKNPLGGLRGAAQLLSK----------ALPDPSL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
AP009378_3 165 ----------LEYTKVIIEQADRLRNLVDRLL 186

AP009378_0630: domain 1 of 1, from 663 to 730: score 59.6, E = 1.6e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l + ++++
AP009378_0 663 IRNALLAALSHDLRTPLTVLFGQAEILTLDL-------ASEGSPH-- 700

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + i++ + rL+n+lLd++ri++g
AP009378_0 701 ----------ARQASEIRQHVLNTTRLVNNLLDMARIQSG 730

AP009378_3226: domain 1 of 1, from 233 to 293: score 55.0, E = 3.2e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e ++
AP009378_3 233 DRTLLMAGVSHDLRTPLTRIRLATEMMSE---------QD------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
AP009378_3 264 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 293

AP009378_1817: domain 1 of 1, from 235 to 301: score 52.3, E = 1.8e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f+ +l+HELRTP++a++g ++ l +++s +
AP009378_1 235 RLSQFADDLAHELRTPINALLGQNQVTLS---------QTRSIAE-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y++ + ++e+e ++rL +++L l+r++ +
AP009378_1 271 ---------YQKTIAGNIEELENISRLTENILFLARADKN 301

AP009378_3992: domain 1 of 1, from 142 to 202: score 45.0, E = 2.2e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+++r+++elL + t+
AP009378_3 142 NERLFTADVAHELRTPLAGVRLHLELLAK---------TH------- 172

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + ++++ + +++lL+l+r+++
AP009378_3 173 ----------HIDVAPLVARLDQMMESVSQLLQLARAGQS 202

AP009378_1470: domain 1 of 1, from 211 to 271: score 42.4, E = 1.2e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ + ls+ +
AP009378_1 211 SKKQLIDGIAHELRTPLVRLRYRLEMSDN-----------LSAAE-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
AP009378_1 245 -------------SQALNRDISQLEALIEELLTYARLDRP 271


Histogram of all scores:
score obs exp (one = represents 14 sequences)
----- --- ---
-15 1 0|=
-14 13 0|=
-13 53 3|*===
-12 207 99|=======*=======
-11 443 514|================================ *
-10 758 953|======================================================= *
-9 803 985|==========================================================*
-8 722 737|====================================================*
-7 543 464|=================================*=====
-6 323 267|===================*====
-5 206 146|==========*====
-4 95 78|=====*=
-3 56 41|==*=
-2 28 21|=*
-1 34 11|*==
0 16 5|*=
1 6 3|*
2 6 1|*
3 2 0|=
4 0 0|
> 5 23 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 322.3698
P(chi-square) = 0

Total sequences searched: 4338

Whole sequence top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: