Acidobacteria Actinobacteria Alphaproteobacteria
Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria
Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
Search:
132 projects found  

5 accessions found for   

Data for AP010803  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AP010803.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AP010803_2885 CDS_2883662-2884918 90.7 2e-25 1
AP010803_1645 CDS_1638450-1640795 74.6 7.2e-21 1
AP010803_0934 CDS_941923-938777 68.9 3.1e-19 1
AP010803_1079 CDS_1085340-1083745 56.0 1.3e-15 2
AP010803_1672 CDS_1673713-1671449 49.8 8e-14 1
AP010803_3283 CDS_3270804-3268402 47.5 3.5e-13 1
AP010803_1674 CDS_1676363-1675254 45.5 1.3e-12 1
AP010803_1635 CDS_1625760-1627478 45.0 1.8e-12 1
AP010803_3110 CDS_3090584-3089229 41.5 1.8e-11 1
AP010803_0716 CDS_731878-730457 36.8 3.8e-10 1
AP010803_0493 CDS_498296-499831 36.3 5.2e-10 1
AP010803_0601 CDS_614584-612521 34.3 1.9e-09 1
AP010803_2578 CDS_2598604-2597285 33.7 2.9e-09 1
AP010803_2775 CDS_2775695-2777686 33.2 3.9e-09 1
AP010803_2542 CDS_2561316-2559973 32.1 8e-09 1
AP010803_2271 CDS_2288541-2290112 32.1 8.1e-09 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AP010803_2885 1/1 181 249 .. 1 87 [] 90.7 2e-25
AP010803_1645 1/1 558 626 .. 1 87 [] 74.6 7.2e-21
AP010803_0934 1/1 678 741 .. 1 87 [] 68.9 3.1e-19
AP010803_1079 2/2 296 361 .. 1 87 [] 54.5 3.7e-15
AP010803_1672 1/1 503 574 .. 1 87 [] 49.8 8e-14
AP010803_3283 1/1 426 492 .. 1 87 [] 47.5 3.5e-13
AP010803_1674 1/1 140 204 .. 1 87 [] 45.5 1.3e-12
AP010803_1635 1/1 339 407 .. 1 87 [] 45.0 1.8e-12
AP010803_3110 1/1 247 305 .. 1 87 [] 41.5 1.8e-11
AP010803_0716 1/1 255 320 .. 1 87 [] 36.8 3.8e-10
AP010803_0493 1/1 282 353 .. 1 87 [] 36.3 5.2e-10
AP010803_0601 1/1 307 374 .. 1 87 [] 34.3 1.9e-09
AP010803_2578 1/1 228 280 .. 1 81 [. 33.7 2.9e-09
AP010803_2775 1/1 285 352 .. 1 87 [] 33.2 3.9e-09
AP010803_2542 1/1 238 296 .. 1 87 [] 32.1 8e-09
AP010803_2271 1/1 147 213 .. 1 87 [] 32.1 8.1e-09

Alignments of top-scoring domains:
AP010803_2885: domain 1 of 1, from 181 to 249: score 90.7, E = 2e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +f+an+sHELRTPL++I+g++e+L + ++ ++ +e
AP010803_2 181 MRVDFVANASHELRTPLAGILGFIETLAD------PELGKDDETR-- 219

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l++++ ea+r++rLi+dl lsriea+
AP010803_2 220 ----------QRFLKIMDGEARRMQRLIDDLISLSRIEAE 249

AP010803_1645: domain 1 of 1, from 558 to 626: score 74.6, E = 7.2e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f+ n+s ELRTPLt+I g+ae++ +++ +els+
AP010803_1 558 VKTAFVTNMSYELRTPLTTIAGFAEMMSAGYA------GELSASA-- 596

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ey++ il++++rl+ Li+++Ldl++ eag
AP010803_1 597 ----------KEYVDGILQSTNRLSMLIDNVLDLTQGEAG 626

AP010803_0934: domain 1 of 1, from 678 to 741: score 68.9, E = 3.1e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+f+ ++sHE+RTPL++I+gya+lL + ++ ++
AP010803_0 678 AKSRFIVGISHEIRTPLNTISGYAQLLDK------------DPAHL- 711

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++++i+r+a +l +Li+ l d srie+g
AP010803_0 712 ----------ADAVRVIRRSATHLTDLIDGLVDVSRIENG 741

AP010803_1079: domain 2 of 2, from 296 to 361: score 54.5, E = 3.7e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + f+a++sHEL++P++++r ++++L + +++e
AP010803_1 296 ATDAFAADVSHELKNPIASLRSALDALDR---------VDKPELR-- 331

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++++++rl+rL+ d+ + sri+a+
AP010803_1 332 ----------AQLMAIAQDDVRRLDRLVTDIAEASRIDAQ 361

AP010803_1672: domain 1 of 1, from 503 to 574: score 49.8, E = 8e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a s+ ++ ++HE+++PLt I+++ae L++++ +e +++++
AP010803_1 503 AWSDVARRIAHEIKNPLTPIQLAAERLQRRYA------EEVTSDKAT 543

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ ti r++ l+r+++++ ++r+ +
AP010803_1 544 ---------FTRLTGTIVRQVGDLRRIVDEFSSFARMPKP 574

AP010803_3283: domain 1 of 1, from 426 to 492: score 47.5, E = 3.5e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++ +++H++++ LtaI+g+++l+l+ +++ ++ +
AP010803_3 426 AIGQLAGGVAHDFNNILTAIIGHCDLMLM--------RHTPGDSD-- 462

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++ i++ ++r L ++lL +sr ++
AP010803_3 463 ----------YDDIQQIKSNSNRAAGLTRQLLAFSRQQTL 492

AP010803_1674: domain 1 of 1, from 140 to 204: score 45.5, E = 1.3e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +a l+HE+++PL++Irg+a+lL+ + +
AP010803_1 140 SAIGAAAILAHEIKNPLSGIRGAAQLLES----------GNDGRD-- 174

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ i +e++r+ +Li+++ d++ ++
AP010803_1 175 ----------AALTQLICNEVDRIAALIDRMQDFTTDRTL 204

AP010803_1635: domain 1 of 1, from 339 to 407: score 45.0, E = 1.8e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++ l HELRTPL+aI+g+ae+++ el+ +++++e
AP010803_1 339 LSADSIRQLVHELRTPLNAILGFAEIIEQELF------GPAGPEY-- 377

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++ +i +a++ll +dl +r g
AP010803_1 378 ----------RDMAGKIAVDARHLLTAFDDLDLAARVSRG 407

AP010803_3110: domain 1 of 1, from 247 to 305: score 41.5, E = 1.8e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k+++l ++ H+LRTPL+++r ae ++ e +
AP010803_3 247 EKDRMLGAIGHDLRTPLASLRVRAESVED-------------EGE-- 278

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + ++ ++r+++d+L l+r++
AP010803_3 279 -------------RARMSETIDEMNRMLEDILSLARAGRS 305

AP010803_0716: domain 1 of 1, from 255 to 320: score 36.8, E = 3.8e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ ++ +l+H+L+ P+t ++ +e + + +++++
AP010803_0 255 QLRMMTDGLAHDLKSPVTRLISVVEQASA---------QTRDDTA-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++le++++ea+ l++++ L +sr eag
AP010803_0 291 ----------LDALEKVHHEAQTLRSMLTTALLISRTEAG 320

AP010803_0493: domain 1 of 1, from 282 to 353: score 36.3, E = 5.2e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++++l+HEL++PL+a+ +y+e++++ l +e+++e
AP010803_0 282 AMGTMASTLAHELNQPLAAVALYLETIRDML-------DERDDEP-F 320

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
L r + + +e+ r +++++l+d+ ++
AP010803_0 321 VSL-------RSVMDDAAQETLRAGHIVRRLRDFVARGEV 353

AP010803_0601: domain 1 of 1, from 307 to 374: score 34.3, E = 1.9e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++ +++H++++ L + g++elL++ l+e+q
AP010803_0 307 TLGQLTGGVAHDFNNLLQIVTGNLELLQR----------GLNEDQ-- 341

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+Rl r++ + + aer L ++lL ++r +
AP010803_0 342 --ARL-----RRAADNAMAGAERAALLTQRLLAFARRQPL 374

AP010803_2578: domain 1 of 1, from 228 to 280: score 33.7, E = 2.9e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++e la++ H++RTPL+ +r+ +e L +
AP010803_2 228 ERTETLAAVGHDMRTPLARLRLRLENLPD------------------ 256

peLRledpeyreyletilreaerllrLindlLdl<-*
e+ e i+ ++ + ++i+ lL +
AP010803_2 257 ----------NEAREAIEGDLTEMGEMIDSLLAF 280

AP010803_2775: domain 1 of 1, from 285 to 352: score 33.2, E = 3.9e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++ +++H++++ L+++ g +el++++l l ++++
AP010803_2 285 AVGQLTGGIAHDFNNMLAVVVGGLELAKRKL--------RLKPQEA- 322

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ l+ + + a+r +L ++lL ++r e
AP010803_2 323 ----------NRHLDNAMEGANRAAALTRRLLAFARSEPL 352

AP010803_2542: domain 1 of 1, from 238 to 296: score 32.1, E = 8e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++ l +++H+LRT +t +r+ ae + +
AP010803_2 238 ERTRVLGAIAHDLRTYMTRLRLRAEFIDD------------------ 266

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ r+++ + +L+nd L l+ ++
AP010803_2 267 ----------AGHRDRAVRDLDEMTALVNDTLFLADRDTA 296

AP010803_2271: domain 1 of 1, from 147 to 213: score 32.1, E = 8.1e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++ +++H++++ L++I g ++l++ + + +++
AP010803_2 147 AIGKLTGGVAHDFNNLLAVIVGSLDLARH--------RLATGADV-- 183

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+y++ + +aer L +++L ++r ++
AP010803_2 184 ----------SRYIDNAMTAAERGATLTQRMLAFARKQEL 213


Histogram of all scores:
score obs exp (one = represents 12 sequences)
----- --- ---
-14 20 0|==
-13 52 2|*====
-12 184 80|======*=========
-11 338 418|============================= *
-10 588 776|================================================= *
-9 656 801|======================================================= *
-8 612 600|=================================================*=
-7 438 378|===============================*=====
-6 265 217|==================*====
-5 162 119|=========*====
-4 101 63|=====*===
-3 41 33|==*=
-2 24 17|=*
-1 13 9|*=
0 7 4|*
1 5 2|*
2 0 1|*
3 0 0|
4 1 0|=
5 0 0|
> 6 22 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 281.8859
P(chi-square) = 0

Total sequences searched: 3529

Whole sequence top hits:
tophits_s report:
Total hits: 16
Satisfying E cutoff: 16
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 16
Satisfying E cutoff: 16
Total memory: 27K


Acknowledgements:

This research is funded by:

Developed by: