Acidobacteria Actinobacteria Alphaproteobacteria
Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria
Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
Search:
264 projects found  

5 accessions found for Escherichia coli O26:H11 str. 11368  

Data for AP010953  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: AP010953.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
AP010953_3856 CDS_3798261-3801017 100.1 6.8e-28 1
AP010953_0432 CDS_463145-464440 91.0 2.7e-25 1
AP010953_3430 CDS_3342536-3346129 81.6 1.2e-22 1
AP010953_1548 CDS_1547547-1544803 80.7 2.1e-22 1
AP010953_3145 CDS_3081778-3078977 80.6 2.4e-22 1
AP010953_4314 CDS_4283137-4280801 78.9 7.2e-22 1
AP010953_3603 CDS_3540018-3538591 75.4 7e-21 1
AP010953_2990 CDS_2916093-2917496 69.8 2.8e-19 1
AP010953_4673 CDS_4670148-4671521 66.6 2.1e-18 1
AP010953_5605 CDS_5692284-5693708 62.4 3.3e-17 1
AP010953_5112 CDS_5167436-5168812 61.5 6e-17 1
AP010953_0642 CDS_681679-680231 61.0 8.4e-17 1
AP010953_4721 CDS_4722525-4723574 59.7 2e-16 1
AP010953_4127 CDS_4093634-4094983 59.6 2e-16 1
AP010953_0757 CDS_809321-806637 59.6 2.1e-16 1
AP010953_4492 CDS_4454020-4452668 55.0 4.2e-15 1
AP010953_2852 CDS_2747594-2746236 52.3 2.4e-14 1
AP010953_5224 CDS_5299568-5298477 45.0 2.9e-12 1
AP010953_2337 CDS_2262844-2264145 42.4 1.6e-11 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
AP010953_3856 1/1 292 357 .. 1 87 [] 100.1 6.8e-28
AP010953_0432 1/1 203 269 .. 1 87 [] 91.0 2.7e-25
AP010953_3430 1/1 711 777 .. 1 87 [] 81.6 1.2e-22
AP010953_1548 1/1 443 508 .. 1 87 [] 80.7 2.1e-22
AP010953_3145 1/1 453 518 .. 1 87 [] 80.6 2.4e-22
AP010953_4314 1/1 282 347 .. 1 87 [] 78.9 7.2e-22
AP010953_3603 1/1 249 317 .. 1 87 [] 75.4 7e-21
AP010953_2990 1/1 240 304 .. 1 87 [] 69.8 2.8e-19
AP010953_4673 1/1 238 300 .. 1 87 [] 66.6 2.1e-18
AP010953_5605 1/1 255 320 .. 1 87 [] 62.4 3.3e-17
AP010953_5112 1/1 237 303 .. 1 87 [] 61.5 6e-17
AP010953_0642 1/1 261 327 .. 1 87 [] 61.0 8.4e-17
AP010953_4721 1/1 129 186 .. 1 79 [. 59.7 2e-16
AP010953_4127 1/1 236 302 .. 1 87 [] 59.6 2e-16
AP010953_0757 1/1 663 730 .. 1 87 [] 59.6 2.1e-16
AP010953_4492 1/1 233 293 .. 1 87 [] 55.0 4.2e-15
AP010953_2852 1/1 235 301 .. 1 87 [] 52.3 2.4e-14
AP010953_5224 1/1 142 202 .. 1 87 [] 45.0 2.9e-12
AP010953_2337 1/1 211 271 .. 1 87 [] 42.4 1.6e-11

Alignments of top-scoring domains:
AP010953_3856: domain 1 of 1, from 292 to 357: score 100.1, E = 6.8e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ tel++ q
AP010953_3 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------TELTPTQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ti+r+a+ ll++ind+Ld+s++eag
AP010953_3 328 ----------RDHLNTIERSANNLLAIINDVLDFSKLEAG 357

AP010953_0432: domain 1 of 1, from 203 to 269: score 91.0, E = 2.7e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e++ e ++l r
AP010953_0 203 ARRNFFANVSHELRTPLTVLQGYLEMMDE---------QPLEGAVR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t++++++r++ L+ +lL+ls+iea
AP010953_0 240 ----------EKALHTMREQTQRMEGLVKQLLTLSKIEAA 269

AP010953_3430: domain 1 of 1, from 711 to 777: score 81.6, E = 1.2e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fla++sHE+RTP+++I+g++elL + ls eqr
AP010953_3 711 AKSQFLATMSHEIRTPISSIMGFLELLSG---------SGLSKEQR- 747

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+++ ++ +++ll Li ++Ld +ie+g
AP010953_3 748 ----------VEAISLAYATGQSLLGLIGEILDVDKIESG 777

AP010953_1548: domain 1 of 1, from 443 to 508: score 80.7, E = 2.1e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL +I+g+a+lL + ++ q
AP010953_1 443 AKSAFLAAMSHEIRTPLYGILGTAQLLAD---------NPALNAQ-- 478

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ i +++e+ll ++nd+Ld+s ieag
AP010953_1 479 ----------RDDLRAITDSGESLLTILNDILDYSAIEAG 508

AP010953_3145: domain 1 of 1, from 453 to 518: score 80.6, E = 2.4e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
AP010953_3 453 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPKGV-- 488

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
AP010953_3 489 ----------DRLVTAMNNSSSLLLKIISDILDFSKIESE 518

AP010953_4314: domain 1 of 1, from 282 to 347: score 78.9, E = 7.2e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ tel++eq
AP010953_4 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TELTAEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
AP010953_4 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

AP010953_3603: domain 1 of 1, from 249 to 317: score 75.4, E = 7e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +fl++lsHEL+TPL+++r +elL +++ ++l++eq
AP010953_3 249 QRHQFLRHLSHELKTPLASMREGTELLADQV------VGPLTPEQ-- 287

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e +++++++++ l++Li++lLd+ r +a
AP010953_3 288 ----------KEVVSILDSSSRNLQKLIEQLLDYNRKQAD 317

AP010953_2990: domain 1 of 1, from 240 to 304: score 69.8, E = 2.8e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPL+++rg +e++++++ + ++e+
AP010953_2 240 MRRDFMADISHELRTPLAVLRGELEAIQDGV-------RKFTPET-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ e+ l +L++dl +ls ++g
AP010953_2 278 -------------VASLQAEVGTLTKLVDDLHQLSMSDEG 304

AP010953_4673: domain 1 of 1, from 238 to 300: score 66.6, E = 2.1e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
AP010953_4 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RSGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr ++
AP010953_4 274 -------------LERIETEAQRLDSMINDLLVMSRNQQK 300

AP010953_5605: domain 1 of 1, from 255 to 320: score 62.4, E = 3.3e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l HEL+ PL+aIrg+ae+L+e ++ +e
AP010953_5 255 YIEQYVYALTHELKSPLAAIRGAAEILRE---------GPPPEVV-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ il + r+++L++ lL +r+e+
AP010953_5 291 ----------ARFTDNILTQNARMQALVETLLRQARLENR 320

AP010953_5112: domain 1 of 1, from 237 to 303: score 61.5, E = 6e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE+R+PL++I+g+a+ e +++++ e
AP010953_5 237 ALGHLAAGVAHEIRNPLSSIKGLAKYFAE--------RAPAGGEA-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++ +ea+rl+r +++lL+l + +
AP010953_5 274 ----------HQLAQVMAKEADRLNRVVSELLELVKPTHL 303

AP010953_0642: domain 1 of 1, from 261 to 327: score 61.0, E = 8.4e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s f a+++HE+RTP+t +++ +e++l + +s +++
AP010953_0 261 RQSNFSADIAHEIRTPITNLITQTEIALS---------QSRSQKEL- 297

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l + l+e+ r+ ++++d+L l++++++
AP010953_0 298 ----------EDVLYSNLEELTRMAKMVSDMLFLAQADNN 327

AP010953_4721: domain 1 of 1, from 129 to 186: score 59.7, E = 2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
AP010953_4 129 AARDLVRGLAHEIKNPLGGLRGAAQLLSK----------ALPDPSL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
AP010953_4 165 ----------LEYTKVIIEQADRLRNLVDRLL 186

AP010953_4127: domain 1 of 1, from 236 to 302: score 59.6, E = 2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PLta++ +e+++ ++ +++ r
AP010953_4 236 RERRFTSDAAHELRSPLTALKVQTEVAQL---------SDDDPQAR- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l ++ ++r rL+++lL+lsr+++
AP010953_4 273 ----------KKALLQLHYGIDRATRLVDQLLTLSRLDSL 302

AP010953_0757: domain 1 of 1, from 663 to 730: score 59.6, E = 2.1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l + ++++
AP010953_0 663 IRNALLAALSHDLRTPLTVLFGQAEILTLDL-------ASEGSPH-- 700

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + i++ + rL+n+lLd++ri++g
AP010953_0 701 ----------ARQASEIRQHVLNTTRLVNNLLDMARIQSG 730

AP010953_4492: domain 1 of 1, from 233 to 293: score 55.0, E = 4.2e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e ++
AP010953_4 233 DRTLLMAGVSHDLRTPLTRIRLATEMMSE---------QD------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
AP010953_4 264 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 293

AP010953_2852: domain 1 of 1, from 235 to 301: score 52.3, E = 2.4e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f+ +l+HELRTP++a++g ++ l +++s +
AP010953_2 235 RLSQFADDLAHELRTPINALLGQNQVTLS---------QTRSIAE-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y++ + ++e+e ++rL +++L l+r++ +
AP010953_2 271 ---------YQKTIAGNIEELENISRLTENILFLARADKN 301

AP010953_5224: domain 1 of 1, from 142 to 202: score 45.0, E = 2.9e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+++r+++elL + t+
AP010953_5 142 NERLFTADVAHELRTPLAGVRLHLELLAK---------TH------- 172

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + ++++ + +++lL+l+r+++
AP010953_5 173 ----------HIDVAPLVARLDQMMESVSQLLQLARAGQS 202

AP010953_2337: domain 1 of 1, from 211 to 271: score 42.4, E = 1.6e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ + ls+ +
AP010953_2 211 SKKQLIDGIAHELRTPLVRLRYRLEMSDN-----------LSAAE-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
AP010953_2 245 -------------SQALNRDISQLEALIEELLTYARLDRP 271


Histogram of all scores:
score obs exp (one = represents 18 sequences)
----- --- ---
-16 1 0|=
-15 6 0|=
-14 21 0|==
-13 84 4|*====
-12 302 122|======*==========
-11 562 635|================================ *
-10 944 1179|===================================================== *
-9 1049 1218|==========================================================*
-8 857 912|================================================ *
-7 590 574|===============================*=
-6 397 330|==================*====
-5 240 181|==========*===
-4 123 97|=====*=
-3 63 51|==*=
-2 36 26|=*
-1 33 14|*=
0 18 7|*
1 6 3|*
2 9 1|*
3 2 1|*
4 0 0|
> 5 21 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 431.0948
P(chi-square) = 0

Total sequences searched: 5609

Whole sequence top hits:
tophits_s report:
Total hits: 19
Satisfying E cutoff: 19
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 19
Satisfying E cutoff: 19
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: