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Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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264 projects found  

3 accessions found for Escherichia coli O157:H7 str. Sakai  

Data for BA000007  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: BA000007.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
BA000007_3646 CDS_3637456-3640212 100.1 6.5e-28 1
BA000007_0450 CDS_479870-481165 91.0 2.6e-25 1
BA000007_3249 CDS_3212511-3216104 81.6 1.1e-22 1
BA000007_1148 CDS_1234501-1231787 80.7 2e-22 1
BA000007_3107 CDS_3052815-3050014 80.6 2.3e-22 1
BA000007_4089 CDS_4095378-4093042 78.9 6.9e-22 1
BA000007_3422 CDS_3411527-3410037 75.4 6.7e-21 1
BA000007_2886 CDS_2838310-2839713 69.8 2.6e-19 1
BA000007_4837 CDS_4904935-4903562 66.6 2.1e-18 1
BA000007_5357 CDS_5493494-5494918 62.4 3.1e-17 1
BA000007_4926 CDS_5010751-5012127 61.5 5.8e-17 1
BA000007_0608 CDS_677430-675982 61.0 8e-17 1
BA000007_3909 CDS_3910431-3911261 60.7 1e-16 1
BA000007_4791 CDS_4852250-4851201 59.7 1.9e-16 1
BA000007_0723 CDS_802841-800157 59.6 2e-16 1
BA000007_4246 CDS_4248062-4246710 55.0 4e-15 1
BA000007_2706 CDS_2662691-2661333 52.3 2.3e-14 1
BA000007_5094 CDS_5187721-5186630 45.0 2.7e-12 1
BA000007_2315 CDS_2282683-2283984 42.4 1.5e-11 1
BA000007_5074 CDS_5166453-5168723 36.1 9.1e-10 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
BA000007_3646 1/1 292 357 .. 1 87 [] 100.1 6.5e-28
BA000007_0450 1/1 203 269 .. 1 87 [] 91.0 2.6e-25
BA000007_3249 1/1 711 777 .. 1 87 [] 81.6 1.1e-22
BA000007_1148 1/1 433 498 .. 1 87 [] 80.7 2e-22
BA000007_3107 1/1 453 518 .. 1 87 [] 80.6 2.3e-22
BA000007_4089 1/1 282 347 .. 1 87 [] 78.9 6.9e-22
BA000007_3422 1/1 270 338 .. 1 87 [] 75.4 6.7e-21
BA000007_2886 1/1 240 304 .. 1 87 [] 69.8 2.6e-19
BA000007_4837 1/1 238 300 .. 1 87 [] 66.6 2.1e-18
BA000007_5357 1/1 255 320 .. 1 87 [] 62.4 3.1e-17
BA000007_4926 1/1 237 303 .. 1 87 [] 61.5 5.8e-17
BA000007_0608 1/1 261 327 .. 1 87 [] 61.0 8e-17
BA000007_3909 1/1 63 129 .. 1 87 [] 60.7 1e-16
BA000007_4791 1/1 129 186 .. 1 79 [. 59.7 1.9e-16
BA000007_0723 1/1 663 730 .. 1 87 [] 59.6 2e-16
BA000007_4246 1/1 233 293 .. 1 87 [] 55.0 4e-15
BA000007_2706 1/1 235 301 .. 1 87 [] 52.3 2.3e-14
BA000007_5094 1/1 142 202 .. 1 87 [] 45.0 2.7e-12
BA000007_2315 1/1 211 271 .. 1 87 [] 42.4 1.5e-11
BA000007_5074 1/1 400 462 .. 1 87 [] 36.1 9.1e-10

Alignments of top-scoring domains:
BA000007_3646: domain 1 of 1, from 292 to 357: score 100.1, E = 6.5e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ tel++ q
BA000007_3 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------TELTPTQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ti+r+a+ ll++ind+Ld+s++eag
BA000007_3 328 ----------RDHLNTIERSANNLLAIINDVLDFSKLEAG 357

BA000007_0450: domain 1 of 1, from 203 to 269: score 91.0, E = 2.6e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e++ e ++l r
BA000007_0 203 ARRNFFANVSHELRTPLTVLQGYLEMMDE---------QPLEGAVR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t++++++r++ L+ +lL+ls+iea
BA000007_0 240 ----------EKALHTMREQTQRMEGLVKQLLTLSKIEAA 269

BA000007_3249: domain 1 of 1, from 711 to 777: score 81.6, E = 1.1e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fla++sHE+RTP+++I+g++elL + ls eqr
BA000007_3 711 AKSQFLATMSHEIRTPISSIMGFLELLSG---------SGLSKEQR- 747

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+++ ++ +++ll Li ++Ld +ie+g
BA000007_3 748 ----------VEAISLAYATGQSLLGLIGEILDVDKIESG 777

BA000007_1148: domain 1 of 1, from 433 to 498: score 80.7, E = 2e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL +I+g+a+lL + ++ q
BA000007_1 433 AKSAFLAAMSHEIRTPLYGILGTAQLLAD---------NPALNAQ-- 468

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ i +++e+ll ++nd+Ld+s ieag
BA000007_1 469 ----------RDDLRAITDSGESLLTILNDILDYSAIEAG 498

BA000007_3107: domain 1 of 1, from 453 to 518: score 80.6, E = 2.3e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
BA000007_3 453 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPKGV-- 488

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
BA000007_3 489 ----------DRLVTAMNNSSSLLLKIISDILDFSKIESE 518

BA000007_4089: domain 1 of 1, from 282 to 347: score 78.9, E = 6.9e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ tel++eq
BA000007_4 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TELTAEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
BA000007_4 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

BA000007_3422: domain 1 of 1, from 270 to 338: score 75.4, E = 6.7e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +fl++lsHEL+TPL+++r +elL +++ ++l++eq
BA000007_3 270 QRHQFLRHLSHELKTPLASMREGTELLADQV------VGPLTPEQ-- 308

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e +++++++++ l++Li++lLd+ r +a
BA000007_3 309 ----------KEVVSILDSSSRNLQKLIEQLLDYNRKQAD 338

BA000007_2886: domain 1 of 1, from 240 to 304: score 69.8, E = 2.6e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPL+++rg +e++++++ + ++e+
BA000007_2 240 MRRDFMADISHELRTPLAVLRGELEAIQDGV-------RKFTPET-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ e+ l +L++dl +ls ++g
BA000007_2 278 -------------VASLQAEVGTLTKLVDDLHQLSMSDEG 304

BA000007_4837: domain 1 of 1, from 238 to 300: score 66.6, E = 2.1e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
BA000007_4 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RSGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr ++
BA000007_4 274 -------------LERIETEAQRLDSMINDLLVMSRNQQK 300

BA000007_5357: domain 1 of 1, from 255 to 320: score 62.4, E = 3.1e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l HEL+ PL+aIrg+ae+L+e ++ +e
BA000007_5 255 YIEQYVYALTHELKSPLAAIRGAAEILRE---------GPPPEVV-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ il + r+++L++ lL +r+e+
BA000007_5 291 ----------ARFTDNILTQNARMQALVETLLRQARLENR 320

BA000007_4926: domain 1 of 1, from 237 to 303: score 61.5, E = 5.8e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE+R+PL++I+g+a+ e +++++ e
BA000007_4 237 ALGHLAAGVAHEIRNPLSSIKGLAKYFAE--------RAPAGGEA-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++ +ea+rl+r +++lL+l + +
BA000007_4 274 ----------HQLAQVMAKEADRLNRVVSELLELVKPTHL 303

BA000007_0608: domain 1 of 1, from 261 to 327: score 61.0, E = 8e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s f a+++HE+RTP+t +++ +e++l + +s +++
BA000007_0 261 RQSNFSADIAHEIRTPITNLITQTEIALS---------QSRSQKEL- 297

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l + l+e+ r+ ++++d+L l++++++
BA000007_0 298 ----------EDVLYSNLEELTRMAKMVSDMLFLAQADNN 327

BA000007_3909: domain 1 of 1, from 63 to 129: score 60.7, E = 1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PLta++ +e+++ ++ +++ r
BA000007_3 63 RERRFTSDAAHELRSPLTALKVQTEVAQL---------SDDDPQAR- 99

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l +++ ++r rL+++lL+lsr+++
BA000007_3 100 ----------KKALLQLHSGIDRATRLVDQLLTLSRLDSL 129

BA000007_4791: domain 1 of 1, from 129 to 186: score 59.7, E = 1.9e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
BA000007_4 129 AARDLVRGLAHEIKNPLGGLRGAAQLLSK----------ALPDPSL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
BA000007_4 165 ----------LEYTKVIIEQADRLRNLVDRLL 186

BA000007_0723: domain 1 of 1, from 663 to 730: score 59.6, E = 2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l + ++++
BA000007_0 663 IRNALLAALSHDLRTPLTVLFGQAEILTLDL-------ASEGSPH-- 700

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + i++ + rL+n+lLd++ri++g
BA000007_0 701 ----------ARQASEIRQHVLNTTRLVNNLLDMARIQSG 730

BA000007_4246: domain 1 of 1, from 233 to 293: score 55.0, E = 4e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e ++
BA000007_4 233 DRTLLMAGVSHDLRTPLTRIRLATEMMSE---------QD------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
BA000007_4 264 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 293

BA000007_2706: domain 1 of 1, from 235 to 301: score 52.3, E = 2.3e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f+ +l+HELRTP++a++g ++ l +++s +
BA000007_2 235 RLSQFADDLAHELRTPINALLGQNQVTLS---------QTRSIAE-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y++ + ++e+e ++rL +++L l+r++ +
BA000007_2 271 ---------YQKTIAGNIEELENISRLTENILFLARADKN 301

BA000007_5094: domain 1 of 1, from 142 to 202: score 45.0, E = 2.7e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+++r+++elL + t+
BA000007_5 142 NERLFTADVAHELRTPLAGVRLHLELLAK---------TH------- 172

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + ++++ + +++lL+l+r+++
BA000007_5 173 ----------HIDVAPLVARLDQMMESVSQLLQLARAGQS 202

BA000007_2315: domain 1 of 1, from 211 to 271: score 42.4, E = 1.5e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ + ls+ +
BA000007_2 211 SKKQLIDGIAHELRTPLVRLRYRLEMSDN-----------LSAAE-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
BA000007_2 245 -------------SQALNRDISQLEALIEELLTYARLDRP 271

BA000007_5074: domain 1 of 1, from 400 to 462: score 36.1, E = 9.1e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++ +l+H++++ L++I+g +el + +++
BA000007_5 400 AVGQLTGGLAHDFNNLLAVIIGSLELVNP---------DSPDAPR-- 435

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++l++aer L ++lL +sr ++
BA000007_5 436 -------------IQRALQAAERGALLTQRLLAFSRKQSL 462


Histogram of all scores:
score obs exp (one = represents 18 sequences)
----- --- ---
-16 1 0|=
-15 5 0|=
-14 29 0|==
-13 101 4|*=====
-12 306 122|======*==========
-11 548 635|=============================== *
-10 912 1178|=================================================== *
-9 1046 1217|==========================================================*
-8 869 911|================================================= *
-7 624 574|===============================*===
-6 387 330|==================*===
-5 224 181|==========*==
-4 126 97|=====*=
-3 60 51|==*=
-2 30 26|=*
-1 38 14|*==
0 15 7|*
1 7 3|*
2 7 1|*
3 3 1|*
4 0 0|
5 1 0|=
6 0 0|
> 7 22 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 456.4928
P(chi-square) = 0

Total sequences searched: 5361

Whole sequence top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: