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Classification of phyla is from NCBI page
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106 projects found  

1 accessions found for Corynebacterium diphtheriae NCTC 13129  

Data for BX248353  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: BX248353.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
BX248353_0677 CDS_669450-670892 75.2 3.3e-21 1
BX248353_1893 CDS_1991032-1989473 73.6 9.5e-21 1
BX248353_0376 CDS_357293-358447 65.8 1.5e-18 1
BX248353_0830 CDS_828428-829918 48.6 1.1e-13 1
BX248353_0058 CDS_57667-56540 40.2 2.6e-11 1
BX248353_0277 CDS_255947-255150 35.8 4.8e-10 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
BX248353_0677 1/1 233 300 .. 1 87 [] 75.2 3.3e-21
BX248353_1893 1/1 293 357 .. 1 87 [] 73.6 9.5e-21
BX248353_0376 1/1 149 215 .. 1 87 [] 65.8 1.5e-18
BX248353_0830 1/1 232 304 .. 1 87 [] 48.6 1.1e-13
BX248353_0058 1/1 143 207 .. 1 87 [] 40.2 2.6e-11
BX248353_0277 1/1 41 98 .. 9 87 .] 35.8 4.8e-10

Alignments of top-scoring domains:
BX248353_0677: domain 1 of 1, from 233 to 300: score 75.2, E = 3.3e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +f++++sHELRTPLt++r++a+l+ +e+ ++ls+ +
BX248353_0 233 LQKQFTSDVSHELRTPLTTVRMAADLIVDEA-------DDLSPGT-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++ e + re++r ++L+ dlL++sr +ag
BX248353_0 271 ----------RRASELMVRELDRFEALLADLLEISRHDAG 300

BX248353_1893: domain 1 of 1, from 293 to 357: score 73.6, E = 9.5e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sHELRTPLt+++gyael + ++ ++ +
BX248353_1 293 QMRRFVGDASHELRTPLTSVKGYAELYRS---------GATTDAD-- 328

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+i++ea+r++ L++dlL l+r+e
BX248353_1 329 -----------LVIEKIEDEAKRMSLLVEDLLALTRAEGA 357

BX248353_0376: domain 1 of 1, from 149 to 215: score 65.8, E = 1.5e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+an+sHEL+TP+ ++ ++ae++ e + + eq+
BX248353_0 149 ARRDFVANVSHELKTPVGGMALLAEAITE---------ASDDQEQV- 185

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + +++++ea+rl ++in+l ls+++
BX248353_0 186 ----------EYFGNRLYKEAHRLADMINELISLSKLQGA 215

BX248353_0830: domain 1 of 1, from 232 to 304: score 48.6, E = 1.1e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkv.lagdtelseeqr
+++e++a++ HEL+TPLt++r+++elL + + ++ see++
BX248353_0 232 RQTELVADAGHELKTPLTSMRTNIELLMM----MhNTDSASISEEDK 274

lpeLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + ++ + e l+ Li dl dl+r e+
BX248353_0 275 -----------QALQSDVIAQMEELSTLIGDLIDLARQETS 304

BX248353_0058: domain 1 of 1, from 143 to 207: score 40.2, E = 2.6e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++l++l+HE+ TPL+++ +y++ L++++ +++
BX248353_0 143 VRRQMLSDLAHEMGTPLSVLTAYLDGLQDGV-------VDWNNAN-- 180

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ +++ rl rL +d+ sr+++
BX248353_0 181 -------------HTIMADQLTRLTRLMEDIDYVSRAQEH 207

BX248353_0277: domain 1 of 1, from 41 to 98: score 35.8, E = 4.8e-10
*->lsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrlpeLRledp
l+HE+RTPL+ I+g+aelL + + +
BX248353_0 41 LAHEIRTPLSLIKGAAELLGQ---------ESDPHKC---------- 68

eyreyletilreaerllrLindlLdlsrieag<-*
++++ ti + r + + +L +++ +g
BX248353_0 69 --ERLVATIGANSTRAIEVAESFLLQAKLNSG 98


Histogram of all scores:
score obs exp (one = represents 8 sequences)
----- --- ---
-14 10 0|==
-13 42 1|*=====
-12 138 51|======*===========
-11 238 269|============================== *
-10 416 499|==================================================== *
-9 403 515|=================================================== *
-8 401 386|================================================*==
-7 245 243|==============================*
-6 156 140|=================*==
-5 87 76|=========*=
-4 59 41|=====*==
-3 27 21|==*=
-2 20 11|=*=
-1 7 5|*
0 10 3|*=
1 3 1|*
2 2 0|=
3 0 0|
4 1 0|=
5 0 0|
> 6 7 -|=


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 204.4610
P(chi-square) = 8.82e-38

Total sequences searched: 2320

Whole sequence top hits:
tophits_s report:
Total hits: 6
Satisfying E cutoff: 6
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 6
Satisfying E cutoff: 6
Total memory: 23K


Acknowledgements:

This research is funded by:

Developed by: