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2 accessions found for Burkholderia pseudomallei K96243  

Data for BX571965  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: BX571965.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
BX571965_1380 CDS_1593304-1594614 92.0 8.4e-26 1
BX571965_1650 CDS_1895929-1899177 78.0 7.9e-22 1
BX571965_1186 CDS_1354752-1357733 66.0 1.9e-18 1
BX571965_0783 CDS_902367-900811 63.2 1.2e-17 1
BX571965_2337 CDS_2799305-2798211 61.8 3.1e-17 1
BX571965_3456 CDS_4068551-4070035 60.0 1e-16 1
BX571965_0816 CDS_936426-937742 56.0 1.4e-15 1
BX571965_1049 CDS_1206542-1207855 54.5 3.6e-15 1
BX571965_2041 CDS_2420132-2418051 52.5 1.4e-14 1
BX571965_0741 CDS_847321-845513 50.9 3.8e-14 1
BX571965_0039 CDS_38176-39555 49.7 8.2e-14 1
BX571965_2322 CDS_2773508-2776048 42.1 1.2e-11 1
BX571965_0130 CDS_142226-144634 41.3 2e-11 1
BX571965_2115 CDS_2514986-2516344 39.7 5.6e-11 1
BX571965_0431 CDS_463292-465325 34.4 1.8e-09 1
BX571965_0205 CDS_208670-209950 27.1 2.1e-07 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
BX571965_1380 1/1 206 272 .. 1 87 [] 92.0 8.4e-26
BX571965_1650 1/1 493 558 .. 1 87 [] 78.0 7.9e-22
BX571965_1186 1/1 677 748 .. 1 87 [] 66.0 1.9e-18
BX571965_0783 1/1 284 349 .. 1 87 [] 63.2 1.2e-17
BX571965_2337 1/1 136 204 .. 1 87 [] 61.8 3.1e-17
BX571965_3456 1/1 239 304 .. 1 87 [] 60.0 1e-16
BX571965_0816 1/1 213 278 .. 1 87 [] 56.0 1.4e-15
BX571965_1049 1/1 219 277 .. 1 87 [] 54.5 3.6e-15
BX571965_2041 1/1 84 149 .. 1 87 [] 52.5 1.4e-14
BX571965_0741 1/1 235 300 .. 1 87 [] 50.9 3.8e-14
BX571965_0039 1/1 238 304 .. 1 87 [] 49.7 8.2e-14
BX571965_2322 1/1 597 667 .. 1 87 [] 42.1 1.2e-11
BX571965_0130 1/1 540 612 .. 1 87 [] 41.3 2e-11
BX571965_2115 1/1 234 293 .. 1 87 [] 39.7 5.6e-11
BX571965_0431 1/1 432 494 .. 1 81 [. 34.4 1.8e-09
BX571965_0205 1/1 201 270 .. 1 87 [] 27.1 2.1e-07

Alignments of top-scoring domains:
BX571965_1380: domain 1 of 1, from 206 to 272: score 92.0, E = 8.4e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+an+sHEL+TPLt+++g++e+++e +ls+++r
BX571965_1 206 MRRDFVANVSHELKTPLTVLSGFLETMRE---------LPLSDDER- 242

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yle ++++a r+++++ dlL l+++e +
BX571965_1 243 ----------ARYLELMEQQASRMRHIVTDLLVLAKLEGE 272

BX571965_1650: domain 1 of 1, from 493 to 558: score 78.0, E = 7.9e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak f+a++sHE+RTPL+++ g++el+ + ++l +eq
BX571965_1 493 AKVAFFASMSHEIRTPLSSLVGNIELIAR---------GPLAPEQ-- 528

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++ ++ +a+ l +++nd+Ld+s+i+ g
BX571965_1 529 ----------QARVKAMETSARGLMQIVNDVLDFSKIDVG 558

BX571965_1186: domain 1 of 1, from 677 to 748: score 66.0, E = 1.9e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +l+++sH+LRTPLtaI g++++L + + g t +++ r
BX571965_1 677 LRNSLLSAISHDLRTPLTAIVGLSSMLAN-----ARGATREGSPARE 718

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+++ i++ea r+ ++ +lLd++r++ag
BX571965_1 719 ----------DELVDAIHDEALRMTGIVTNLLDMARLQAG 748

BX571965_0783: domain 1 of 1, from 284 to 349: score 63.2, E = 1.2e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +f+a+++H+++TPL+++r+ ae +l+ +e +++
BX571965_0 284 LQKRFIADAAHQMKTPLAGLRTQAEFALR---------HEVNADV-- 319

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ le i ++e+ rL+ +lL l+r+e+
BX571965_0 320 ----------ARSLEQIATSSEQAARLVTQLLALARAENR 349

BX571965_2337: domain 1 of 1, from 136 to 204: score 61.8, E = 3.1e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++nl+HE+++PL +Irg+a+lL+ el +e+ +++
BX571965_2 136 VNKQLIRNLAHEIKNPLGGIRGAAQLLEFEL-------GERERDEL- 174

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
rey+++i++e++rl+ L+++lL+ r +
BX571965_2 175 ----------REYTQVIIKESDRLQTLVDRLLEPHRHPHI 204

BX571965_3456: domain 1 of 1, from 239 to 304: score 60.0, E = 1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a+++H+LRTPLtaI+++ae + +++++q+
BX571965_3 239 AQRKFIADAAHQLRTPLTAIKLHAEQAAV----------ARDPQQA- 274

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ ++++a+r rL n+lL l+r+e g
BX571965_3 275 ----------LTAVRELRSAADRAVRLSNQLLSLARAEPG 304

BX571965_0816: domain 1 of 1, from 213 to 278: score 56.0, E = 1.4e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+a++ a+l + ++++ r
BX571965_0 213 TQKAFVADAAHELRTPLAAVQIQAQLVAR----------AQDDVSR- 248

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re++ +++ + r rL ++lL l+r+e g
BX571965_0 249 ----------REAIVDLQSGVTRATRLAEQLLALARAEPG 278

BX571965_1049: domain 1 of 1, from 219 to 277: score 54.5, E = 3.6e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +la+++H+LRTPL+ +r+ ae++ +
BX571965_1 219 DRAVMLAGVAHDLRTPLARMRLRAEMMDD------------------ 247

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + + r+++++ ++++++L ++ +a
BX571965_1 248 ----------ARLRDGVVRDVDSMTHIVDQFLVFAHGDAD 277

BX571965_2041: domain 1 of 1, from 84 to 149: score 52.5, E = 1.4e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + la++sHELR P++++++++el + + l +eq
BX571965_2 84 ASRGSLATASHELRAPVNGMLALVELVRQ---------GLLAPEQ-- 119

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l +++++++l r +nd+Ld + ieag
BX571965_2 120 ----------QRLLGLVQDSGQSLARVLNDILDHASIEAG 149

BX571965_0741: domain 1 of 1, from 235 to 300: score 50.9, E = 3.8e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ fl ++sHELRTPL aI g +e+Ll+ ++se
BX571965_0 235 AKNAFLGMVSHELRTPLQAICGSIEVLLA---------RPQSEAN-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++++++a +l++++ dl d+ ++++
BX571965_0 271 ----------MKTIKRLQNSAASLEAQVKDLTDYIKLRST 300

BX571965_0039: domain 1 of 1, from 238 to 304: score 49.7, E = 8.2e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+a+++H+LRTP+++I + ++ ++ e ++ +
BX571965_0 238 TQRRFIADAAHQLRTPIAVIDTQIQCARQ---------RENGDAAL- 274

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l +++r+++r+ + + lL l+ +ea
BX571965_0 275 ----------AALLASMQRSSRRMADVTDKLLLLAHAEAA 304

BX571965_2322: domain 1 of 1, from 597 to 667: score 42.1, E = 1.2e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++++++HEL++PL+aI y++ l+ l +++ +s+e++
BX571965_2 597 TMGEMASSIAHELNQPLAAINNYCSGTLA-----LVKSGRASPETL- 637

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +le+ ++a r ++ +++++ + ++
BX571965_2 638 ----------APALEKTAQQALRAGMIVKRIREFVKRSEP 667

BX571965_0130: domain 1 of 1, from 540 to 612: score 41.3, E = 2e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +e ++ l+HE+++PLt I++ ae L+++l +++ls ++ +
BX571965_0 540 AWGEVARRLAHEIKNPLTPIQLSAERLQMKL------SDKLSQPD-A 579

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ L ++ ti +++ + r+++d++d++r
BX571965_0 580 DVL-------KRGATTIVNQVAAMKRMVDDFRDYARTPPA 612

BX571965_2115: domain 1 of 1, from 234 to 293: score 39.7, E = 5.6e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +la++sH+LRTPL+ +r+ +e+ +
BX571965_2 234 DRALMLAGISHDLRTPLARLRLETEMSPSD----------------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + +++e+++r+i + d++r +
BX571965_2 264 ----------QATKDAMVDDIEQMDRIIAAFIDYARPAQR 293

BX571965_0431: domain 1 of 1, from 432 to 494: score 34.4, E = 1.8e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++a++ HEL++PL+a+r +++ + +++e+ ++
BX571965_0 432 ALGQMAAGITHELNQPLAALRSFSDNTRV--------LLDRGEQAAA 470

peLRledpeyreyletilreaerllrLindlLdl<-*
re le i +er+ ++ n+l +
BX571965_0 471 ----------RENLEAIAALTERMGKITNQLKLF 494

BX571965_0205: domain 1 of 1, from 201 to 270: score 27.1, E = 2.1e-07
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ +a+++HE+ TPL++I +++e L+e a +t+++
BX571965_0 201 ALGVQAATVAHEMGTPLSTIAMLTEELRE------AARTDAGLAR-- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y l++++++ ++ + + +l+ + +
BX571965_0 240 ---------YDADLKVLEEQMSQCTSALARLRSRASERPS 270


Histogram of all scores:
score obs exp (one = represents 12 sequences)
----- --- ---
-14 7 0|=
-13 25 2|*==
-12 116 77|======*===
-11 269 402|======================= *
-10 539 747|============================================= *
-9 672 771|======================================================== *
-8 644 577|================================================*=====
-7 452 364|==============================*=======
-6 298 209|=================*=======
-5 174 114|=========*=====
-4 82 61|=====*=
-3 53 32|==*==
-2 28 17|=*=
-1 10 8|*
0 8 4|*
1 1 2|*
2 2 1|*
3 0 0|
> 4 19 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 257.6359
P(chi-square) = 0

Total sequences searched: 3460

Whole sequence top hits:
tophits_s report:
Total hits: 16
Satisfying E cutoff: 16
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 16
Satisfying E cutoff: 16
Total memory: 27K


Acknowledgements:

This research is funded by:

Developed by: