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2 accessions found for Burkholderia pseudomallei K96243  

Data for BX571966  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: BX571966.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
BX571966_0119 CDS_150353-147309 96.1 4e-27 1
BX571966_2289 CDS_3020396-3018081 75.9 2.2e-21 1
BX571966_1057 CDS_1416412-1415018 67.8 4.3e-19 1
BX571966_2030 CDS_2699365-2700819 59.0 1.3e-16 1
BX571966_0656 CDS_876578-875199 57.8 2.9e-16 1
BX571966_0645 CDS_859892-861007 57.1 4.6e-16 1
BX571966_0723 CDS_948067-949566 55.8 1e-15 1
BX571966_0704 CDS_929988-928660 47.4 2.5e-13 1
BX571966_1388 CDS_1862680-1860467 46.5 4.5e-13 1
BX571966_1488 CDS_1993325-1991964 45.0 1.2e-12 1
BX571966_1677 CDS_2263775-2262606 38.0 1.2e-10 2
BX571966_0063 CDS_67529-69460 31.6 7.7e-09 1
BX571966_1827 CDS_2453119-2453898 29.0 4.2e-08 1
BX571966_1910 CDS_2550168-2549071 28.0 7.9e-08 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
BX571966_0119 1/1 532 597 .. 1 87 [] 96.1 4e-27
BX571966_2289 1/1 394 459 .. 1 87 [] 75.9 2.2e-21
BX571966_1057 1/1 242 308 .. 1 87 [] 67.8 4.3e-19
BX571966_2030 1/1 242 308 .. 1 87 [] 59.0 1.3e-16
BX571966_0656 1/1 233 298 .. 1 87 [] 57.8 2.9e-16
BX571966_0645 1/1 156 221 .. 1 87 [] 57.1 4.6e-16
BX571966_0723 1/1 238 303 .. 1 87 [] 55.8 1e-15
BX571966_0704 1/1 207 272 .. 1 87 [] 47.4 2.5e-13
BX571966_1388 1/1 504 572 .. 1 87 [] 46.5 4.5e-13
BX571966_1488 1/1 230 295 .. 1 87 [] 45.0 1.2e-12
BX571966_0063 1/1 407 475 .. 1 87 [] 31.6 7.7e-09
BX571966_1827 1/1 27 94 .. 1 87 [] 29.0 4.2e-08
BX571966_1910 1/1 144 207 .. 1 87 [] 28.0 7.9e-08

Alignments of top-scoring domains:
BX571966_0119: domain 1 of 1, from 532 to 597: score 96.1, E = 4e-27
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL+aI+g++elL++ ++lse+q
BX571966_0 532 AKSTFLATMSHEIRTPLNAIIGNLELLRR---------SPLSEQQ-- 567

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e l++++++++ ll++ind+Ldls+ e+g
BX571966_0 568 ----------SERLHVVESCSNALLHIINDILDLSKVESG 597

BX571966_2289: domain 1 of 1, from 394 to 459: score 75.9, E = 2.2e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+e+la++sHELRTPL++I g +e+L++ + ++ q
BX571966_2 394 LKDELLATVSHELRTPLNVIYGWIEVLRN---------PVDGALQ-- 429

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ i+r+a++l+r++ d+Ld s + +g
BX571966_2 430 ----------QQAIDAIDRSARSLSRMVGDILDASSLATG 459

BX571966_1057: domain 1 of 1, from 242 to 308: score 67.8, E = 4.3e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f +nl+H++RTPLt +++ a+++l ++++++
BX571966_1 242 RLSQFSSNLAHDMRTPLTNLLAEAQVALS---------KPRTADE-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr+ +e+ ++e +rl+r+i+d+L l+r ++
BX571966_1 278 ---------YRDVIESSIDEYQRLSRMIEDMLFLARSDNA 308

BX571966_2030: domain 1 of 1, from 242 to 308: score 59.0, E = 1.3e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ e ++l+H++RTPLt +++ a+++l + +s ++
BX571966_2 242 RLKEYSSDLAHDIRTPLTNLLAEAQVALS---------QRRSVDE-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr+ +e+ +e +rl r+++d+L l+r++
BX571966_2 278 ---------YRQVIESSVEEYQRLARMVDDMLFLARADGH 308

BX571966_0656: domain 1 of 1, from 233 to 298: score 57.8, E = 2.9e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ f+a+++HELRTP+ +++ ++lL++ ++s+++r
BX571966_0 233 LQRHFIADAAHELRTPIMGLSIQTQLLQR----------TASADER- 268

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l i+ + rl++L ++lL+l+r+e +
BX571966_0 269 ----------ARILAQIQAGTTRLSHLAEQLLTLARLEPE 298

BX571966_0645: domain 1 of 1, from 156 to 221: score 57.1, E = 4.6e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++ ++sHELRTPL+ +r+++e L+e + s+ +
BX571966_0 156 TQRDLTNGISHELRTPLARVRFALESLRE----------PGSAAE-- 190

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ ++++i++++ l++Li+ L+++r+e
BX571966_0 191 ---------YQNAIDSIEQDVSELDELIDMSLTYARLEYS 221

BX571966_0723: domain 1 of 1, from 238 to 303: score 55.8, E = 1e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a+++H+L+TPL+a ++ +el+l+ ++ e +
BX571966_0 238 ARRRFFADAAHQLKTPLAAAQAGVELALR----------PAERERV- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l+++ ++++ +++++lL lsr+e+
BX571966_0 274 ----------SVHLRRVNGAVRQAAKIVQQLLSLSRLESD 303

BX571966_0704: domain 1 of 1, from 207 to 272: score 47.4, E = 2.5e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++e++ ++sHEL+TPL+ + + + lL ++++e
BX571966_0 207 QQREMMHGISHELKTPLARLEFGLALLSS---------PDAPERM-- 242

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re ++r+++ l++L+ +lL++ r+e+g
BX571966_0 243 ----------RERQAALRRDVRELDELVTELLTIGRLEQG 272

BX571966_1388: domain 1 of 1, from 504 to 572: score 46.5, E = 4.5e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+ +sH+L PL a+ g ++lL++++ + l++
BX571966_1 504 DLEQFAYVASHDLQEPLRAVAGPLQLLQRRYQ------GQLDARA-- 542

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e++ + + a r+++Li+dlL +sr +
BX571966_1 543 ----------DEFIGHAVDGATRMQSLIDDLLSYSRVGRL 572

BX571966_1488: domain 1 of 1, from 230 to 295: score 45.0, E = 1.2e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + f+an +HELRTP++a ++ ++ L + e+++e +
BX571966_1 230 AERSFTANSAHELRTPIAAALAQTQRLIA----------EAPAEPL- 265

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re ++++ +++ l+r ++l++l+++e g
BX571966_1 266 ----------RERARRVEGALHTLSRVSEQLMQLAKAEDG 295

BX571966_0063: domain 1 of 1, from 407 to 475: score 31.6, E = 7.7e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++a++ HEL++PL+aI+++++ + + + +s++
BX571966_0 407 ALGQMAAGITHELNQPLAAIMTLSSNAVRMAA------LGRSADL-- 445

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ le + + a r+ +++ + ++r e+
BX571966_0 446 ----------TRNLELVNDLAGRMGKIVAHMKGFARHESV 475

BX571966_1827: domain 1 of 1, from 27 to 94: score 29.0, E = 4.2e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ l+ +sH+LR PL+a+ a +L++ + ++s+e +
BX571966_1 27 VRDHALSVASHDLRSPLNAMHSWAYVLER--------RLTASDENL- 64

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+ i+ +e+ +L++ d r+e+
BX571966_1 65 ----------ARALDGIRIGIEQQTKLLETTIDAPRAETR 94

BX571966_1910: domain 1 of 1, from 144 to 207: score 28.0, E = 7.9e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++e l lsH++RTP t+I++++++ ++ ++ + +
BX571966_1 144 QRDEVLDFLSHDMRTPQTSILALLDVYRN---------EHGAMPPI- 180

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ a+r l+L + + l+r++++
BX571966_1 181 -------------LERIETHARRALALADGFIHLTRAQSE 207


Histogram of all scores:
score obs exp (one = represents 8 sequences)
----- --- ---
-15 1 0|=
-14 0 0|
-13 26 1|*===
-12 57 53|======*=
-11 171 276|====================== *
-10 395 512|================================================== *
-9 466 528|==========================================================*
-8 428 395|=================================================*====
-7 329 249|===============================*==========
-6 187 143|=================*======
-5 127 78|=========*======
-4 57 42|=====*==
-3 24 22|==*
-2 22 11|=*=
-1 12 6|*=
0 4 3|*
1 3 1|*
> 2 20 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 165.1560
P(chi-square) = 1.169e-29

Total sequences searched: 2395

Whole sequence top hits:
tophits_s report:
Total hits: 14
Satisfying E cutoff: 14
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 13
Satisfying E cutoff: 13
Total memory: 26K


Acknowledgements:

This research is funded by:

Developed by: