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Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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2 accessions found for Burkholderia mallei ATCC 23344  

Data for CP000010  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000010.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000010_0687 CDS_819872-821182 92.0 7.3e-26 1
CP000010_0235 CDS_289156-287639 61.8 2.7e-17 1
CP000010_1499 CDS_1826745-1825672 61.8 2.7e-17 1
CP000010_2569 CDS_3015502-3014015 60.0 8.8e-17 1
CP000010_0272 CDS_324405-325721 56.0 1.2e-15 1
CP000010_0656 CDS_782305-783618 54.5 3.1e-15 1
CP000010_0751 CDS_914222-916186 52.5 1.2e-14 1
CP000010_2342 CDS_2779431-2778052 49.7 7.1e-14 1
CP000010_1481 CDS_1799457-1802096 42.1 1e-11 1
CP000010_0127 CDS_158732-161152 41.3 1.7e-11 1
CP000010_1269 CDS_1540430-1541788 39.7 4.8e-11 1
CP000010_2864 CDS_3359910-3361190 27.1 1.8e-07 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000010_0687 1/1 206 272 .. 1 87 [] 92.0 7.3e-26
CP000010_0235 1/1 271 336 .. 1 87 [] 61.8 2.7e-17
CP000010_1499 1/1 129 197 .. 1 87 [] 61.8 2.7e-17
CP000010_2569 1/1 240 305 .. 1 87 [] 60.0 8.8e-17
CP000010_0272 1/1 213 278 .. 1 87 [] 56.0 1.2e-15
CP000010_0656 1/1 219 277 .. 1 87 [] 54.5 3.1e-15
CP000010_0751 1/1 45 110 .. 1 87 [] 52.5 1.2e-14
CP000010_2342 1/1 238 304 .. 1 87 [] 49.7 7.1e-14
CP000010_1481 1/1 630 700 .. 1 87 [] 42.1 1e-11
CP000010_0127 1/1 544 616 .. 1 87 [] 41.3 1.7e-11
CP000010_1269 1/1 234 293 .. 1 87 [] 39.7 4.8e-11
CP000010_2864 1/1 201 270 .. 1 87 [] 27.1 1.8e-07

Alignments of top-scoring domains:
CP000010_0687: domain 1 of 1, from 206 to 272: score 92.0, E = 7.3e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+an+sHEL+TPLt+++g++e+++e +ls+++r
CP000010_0 206 MRRDFVANVSHELKTPLTVLSGFLETMRE---------LPLSDDER- 242

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yle ++++a r+++++ dlL l+++e +
CP000010_0 243 ----------ARYLELMEQQASRMRHIVTDLLVLAKLEGE 272

CP000010_0235: domain 1 of 1, from 271 to 336: score 61.8, E = 2.7e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +f+a+++H+++TPL+++r+ ae +l+ +e +++
CP000010_0 271 LQKRFIADAAHQMKTPLAGLRTQAEFALR---------HEVNADV-- 306

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ le i ++e+ rL+ +lL l+r+e+
CP000010_0 307 ----------AHSLEQIATSSEQAARLVTQLLALARAENR 336

CP000010_1499: domain 1 of 1, from 129 to 197: score 61.8, E = 2.7e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++nl+HE+++PL +Irg+a+lL+ el +e+ +++
CP000010_1 129 VNKQLIRNLAHEIKNPLGGIRGAAQLLEFEL-------GERERDEL- 167

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
rey+++i++e++rl+ L+++lL+ r +
CP000010_1 168 ----------REYTQVIIKESDRLQTLVDRLLEPHRHPHI 197

CP000010_2569: domain 1 of 1, from 240 to 305: score 60.0, E = 8.8e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a+++H+LRTPLtaI+++ae + +++++q+
CP000010_2 240 AQRKFIADAAHQLRTPLTAIKLHAEQAAV----------ARDPQQA- 275

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ ++++a+r rL n+lL l+r+e g
CP000010_2 276 ----------LTAVRELRSAADRAVRLSNQLLSLARAEPG 305

CP000010_0272: domain 1 of 1, from 213 to 278: score 56.0, E = 1.2e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+a++ a+l + ++++ r
CP000010_0 213 TQKAFVADAAHELRTPLAAVQIQAQLVAR----------AQDDVSR- 248

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re++ +++ + r rL ++lL l+r+e g
CP000010_0 249 ----------REAIVDLQSGVTRATRLAEQLLALARAEPG 278

CP000010_0656: domain 1 of 1, from 219 to 277: score 54.5, E = 3.1e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +la+++H+LRTPL+ +r+ ae++ +
CP000010_0 219 DRAVMLAGVAHDLRTPLARMRLRAEMMDD------------------ 247

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + + r+++++ ++++++L ++ +a
CP000010_0 248 ----------ARLRDGVVRDVDSMTHIVDQFLVFAHGDAD 277

CP000010_0751: domain 1 of 1, from 45 to 110: score 52.5, E = 1.2e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + la++sHELR P++++++++el + + l +eq
CP000010_0 45 ASRGSLATASHELRAPVNGMLALVELVRQ---------GLLAPEQ-- 80

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l +++++++l r +nd+Ld + ieag
CP000010_0 81 ----------QRLLGLVQDSGQSLARVLNDILDHASIEAG 110

CP000010_2342: domain 1 of 1, from 238 to 304: score 49.7, E = 7.1e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+a+++H+LRTP+++I + ++ ++ e ++ +
CP000010_2 238 TQRRFIADAAHQLRTPIAVIDTQIQCARQ---------RENGDAAL- 274

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l +++r+++r+ + + lL l+ +ea
CP000010_2 275 ----------AALLASMQRSSRRMADVTDKLLLLAHAEAA 304

CP000010_1481: domain 1 of 1, from 630 to 700: score 42.1, E = 1e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++++++HEL++PL+aI y++ l+ l +++ +s+e++
CP000010_1 630 TMGEMASSIAHELNQPLAAINNYCSGTLA-----LVKSGRASPETL- 670

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +le+ ++a r ++ +++++ + ++
CP000010_1 671 ----------APALEKTAQQALRAGMIVKRIREFVKRSEP 700

CP000010_0127: domain 1 of 1, from 544 to 616: score 41.3, E = 1.7e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +e ++ l+HE+++PLt I++ ae L+++l +++ls ++ +
CP000010_0 544 AWGEVARRLAHEIKNPLTPIQLSAERLQMKL------SDKLSQPD-A 583

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ L ++ ti +++ + r+++d++d++r
CP000010_0 584 DVL-------KRGATTIVNQVAAMKRMVDDFRDYARTPPA 616

CP000010_1269: domain 1 of 1, from 234 to 293: score 39.7, E = 4.8e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +la++sH+LRTPL+ +r+ +e+ +
CP000010_1 234 DRALMLAGISHDLRTPLARLRLETEMSPSD----------------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + +++e+++r+i + d++r +
CP000010_1 264 ----------QATKDAMVDDIEQMDRIIAAFIDYARPAQR 293

CP000010_2864: domain 1 of 1, from 201 to 270: score 27.1, E = 1.8e-07
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ +a+++HE+ TPL++I +++e L+e a +t+++
CP000010_2 201 ALGVQAATVAHEMGTPLSTIAMLTEELRE------AARTDAGLAR-- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y l++++++ ++ + + +l+ + +
CP000010_2 240 ---------YDADLKVLEEQMSQCTSALARLRSRASERPS 270


Histogram of all scores:
score obs exp (one = represents 11 sequences)
----- --- ---
-14 5 0|=
-13 38 2|*===
-12 114 68|======*====
-11 270 355|========================= *
-10 489 658|============================================= *
-9 606 680|======================================================== *
-8 564 509|==============================================*=====
-7 363 321|=============================*===
-6 237 184|================*=====
-5 143 101|=========*===
-4 69 54|====*==
-3 45 28|==*==
-2 22 15|=*
-1 7 7|*
0 7 4|*
1 1 2|*
2 1 1|*
3 0 0|
> 4 15 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 162.4901
P(chi-square) = 4.125e-29

Total sequences searched: 2996

Whole sequence top hits:
tophits_s report:
Total hits: 12
Satisfying E cutoff: 12
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 12
Satisfying E cutoff: 12
Total memory: 25K


Acknowledgements:

This research is funded by:

Developed by: