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Classification of phyla is from NCBI page
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2 accessions found for Burkholderia mallei ATCC 23344  

Data for CP000011  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000011.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000011_1894 CDS_2169211-2166896 75.9 1.8e-21 1
CP000011_0979 CDS_1065110-1063716 67.8 3.6e-19 1
CP000011_0791 CDS_859594-858215 57.8 2.5e-16 1
CP000011_0780 CDS_842990-844195 57.1 3.9e-16 1
CP000011_1077 CDS_1181268-1179763 55.8 8.8e-16 1
CP000011_1094 CDS_1199278-1200606 47.4 2.2e-13 1
CP000011_0861 CDS_920625-922796 46.5 3.8e-13 1
CP000011_0750 CDS_808414-809775 45.3 8.7e-13 1
CP000011_1590 CDS_1811339-1810263 38.0 1e-10 2
CP000011_0278 CDS_281350-280571 29.0 3.6e-08 1
CP000011_0207 CDS_212810-213904 28.0 6.7e-08 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000011_1894 1/1 394 459 .. 1 87 [] 75.9 1.8e-21
CP000011_0979 1/1 242 308 .. 1 87 [] 67.8 3.6e-19
CP000011_0791 1/1 233 298 .. 1 87 [] 57.8 2.5e-16
CP000011_0780 1/1 186 251 .. 1 87 [] 57.1 3.9e-16
CP000011_1077 1/1 240 305 .. 1 87 [] 55.8 8.8e-16
CP000011_1094 1/1 207 272 .. 1 87 [] 47.4 2.2e-13
CP000011_0861 1/1 490 558 .. 1 87 [] 46.5 3.8e-13
CP000011_0750 1/1 230 295 .. 1 87 [] 45.3 8.7e-13
CP000011_0278 1/1 27 94 .. 1 87 [] 29.0 3.6e-08
CP000011_0207 1/1 143 206 .. 1 87 [] 28.0 6.7e-08

Alignments of top-scoring domains:
CP000011_1894: domain 1 of 1, from 394 to 459: score 75.9, E = 1.8e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+e+la++sHELRTPL++I g +e+L++ + ++ q
CP000011_1 394 LKDELLATVSHELRTPLNVIYGWIEVLRN---------PVDGALQ-- 429

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ i+r+a++l+r++ d+Ld s + +g
CP000011_1 430 ----------QQAIDAIDRSARSLSRMVGDILDASSLATG 459

CP000011_0979: domain 1 of 1, from 242 to 308: score 67.8, E = 3.6e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f +nl+H++RTPLt +++ a+++l ++++++
CP000011_0 242 RLSQFSSNLAHDMRTPLTNLLAEAQVALS---------KPRTADE-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr+ +e+ ++e +rl+r+i+d+L l+r ++
CP000011_0 278 ---------YRDVIESSIDEYQRLSRMIEDMLFLARSDNA 308

CP000011_0791: domain 1 of 1, from 233 to 298: score 57.8, E = 2.5e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ f+a+++HELRTP+ +++ ++lL++ ++s+++r
CP000011_0 233 LQRHFIADAAHELRTPIMGLSIQTQLLQR----------TASADER- 268

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l i+ + rl++L ++lL+l+r+e +
CP000011_0 269 ----------ARILAQIQAGTTRLSHLAEQLLTLARLEPE 298

CP000011_0780: domain 1 of 1, from 186 to 251: score 57.1, E = 3.9e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++ ++sHELRTPL+ +r+++e L+e + s+ +
CP000011_0 186 TQRDLTNGISHELRTPLARVRFALESLRE----------PGSAAE-- 220

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ ++++i++++ l++Li+ L+++r+e
CP000011_0 221 ---------YQNAIDSIEQDVSELDELIDMSLTYARLEYS 251

CP000011_1077: domain 1 of 1, from 240 to 305: score 55.8, E = 8.8e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a+++H+L+TPL+a ++ +el+l+ ++ e +
CP000011_1 240 ARRRFFADAAHQLKTPLAAAQAGVELALR----------PAERERV- 275

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l+++ ++++ +++++lL lsr+e+
CP000011_1 276 ----------SVHLRRVNGAVRQAAKIVQQLLSLSRLESD 305

CP000011_1094: domain 1 of 1, from 207 to 272: score 47.4, E = 2.2e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++e++ ++sHEL+TPL+ + + + lL ++++e
CP000011_1 207 QQREMMHGISHELKTPLARLEFGLALLSS---------PDAPERM-- 242

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re ++r+++ l++L+ +lL++ r+e+g
CP000011_1 243 ----------RERQAALRRDVRELDELVTELLTIGRLEQG 272

CP000011_0861: domain 1 of 1, from 490 to 558: score 46.5, E = 3.8e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+ +sH+L PL a+ g ++lL++++ + l++
CP000011_0 490 DLEQFAYVASHDLQEPLRAVAGPLQLLQRRYQ------GQLDARA-- 528

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e++ + + a r+++Li+dlL +sr +
CP000011_0 529 ----------DEFIGHAVDGATRMQSLIDDLLSYSRVGRL 558

CP000011_0750: domain 1 of 1, from 230 to 295: score 45.3, E = 8.7e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + f+an +HELRTP++a ++ ++ L + e+++e +
CP000011_0 230 AERSFAANSAHELRTPIAAALAQTQRLIA----------EAPAEPL- 265

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re ++++ +++ l+r ++l++l+++e g
CP000011_0 266 ----------RERARRVEGALHTLSRVSEQLMQLAKAEDG 295

CP000011_0278: domain 1 of 1, from 27 to 94: score 29.0, E = 3.6e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ l+ +sH+LR PL+a+ a +L++ + ++s+e +
CP000011_0 27 VRDHALSVASHDLRSPLNAMHSWAYVLER--------RLTASDENL- 64

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+ i+ +e+ +L++ d r+e+
CP000011_0 65 ----------ARALDGIRIGIEQQTKLLETTIDAPRAETR 94

CP000011_0207: domain 1 of 1, from 143 to 206: score 28.0, E = 6.7e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++e l lsH++RTP t+I++++++ ++ ++ + +
CP000011_0 143 QRDEVLDFLSHDMRTPQTSILALLDVYRN---------EHGAMPPI- 179

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ a+r l+L + + l+r++++
CP000011_0 180 -------------LERIETHARRALALADGFIHLTRAQSE 206


Histogram of all scores:
score obs exp (one = represents 8 sequences)
----- --- ---
-14 7 0|=
-13 37 1|*====
-12 85 46|=====*=====
-11 191 240|======================== *
-10 377 446|================================================ *
-9 428 460|====================================================== *
-8 331 344|==========================================*
-7 251 217|===========================*====
-6 134 125|===============*=
-5 88 68|========*==
-4 38 36|====*
-3 16 19|==*
-2 16 10|=*
-1 9 5|*=
0 3 2|*
1 2 1|*
> 2 16 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 73.7801
P(chi-square) = 2.322e-11

Total sequences searched: 2029

Whole sequence top hits:
tophits_s report:
Total hits: 11
Satisfying E cutoff: 11
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 10
Satisfying E cutoff: 10
Total memory: 24K


Acknowledgements:

This research is funded by:

Developed by: