Acidobacteria Actinobacteria Alphaproteobacteria
Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria
Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
Search:
76 projects found  

2 accessions found for Burkholderia pseudomallei 1710b  

Data for CP000124  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000124.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000124_1606 CDS_1706591-1707901 92.0 9e-26 1
CP000124_2196 CDS_2486880-2483632 78.0 8.5e-22 1
CP000124_1383 CDS_1467658-1470639 66.0 2.1e-18 1
CP000124_0959 CDS_1022252-1019799 63.2 1.3e-17 1
CP000124_2730 CDS_3069349-3068162 61.8 3.3e-17 1
CP000124_0202 CDS_216778-218262 60.0 1.1e-16 1
CP000124_0999 CDS_1055426-1056742 56.0 1.5e-15 1
CP000124_1242 CDS_1302436-1303749 54.5 3.9e-15 1
CP000124_1773 CDS_1956821-1958785 52.5 1.5e-14 1
CP000124_0945 CDS_1004795-1002987 50.9 4e-14 1
CP000124_0247 CDS_260864-262243 49.7 8.9e-14 1
CP000124_2710 CDS_3043446-3046085 42.1 1.3e-11 1
CP000124_0344 CDS_368917-371280 41.3 2.1e-11 1
CP000124_2477 CDS_2774692-2776029 39.7 6e-11 1
CP000124_0632 CDS_654686-656719 34.4 1.9e-09 1
CP000124_0374 CDS_398949-400229 27.1 2.3e-07 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000124_1606 1/1 206 272 .. 1 87 [] 92.0 9e-26
CP000124_2196 1/1 493 558 .. 1 87 [] 78.0 8.5e-22
CP000124_1383 1/1 677 748 .. 1 87 [] 66.0 2.1e-18
CP000124_0959 1/1 583 648 .. 1 87 [] 63.2 1.3e-17
CP000124_2730 1/1 167 235 .. 1 87 [] 61.8 3.3e-17
CP000124_0202 1/1 239 304 .. 1 87 [] 60.0 1.1e-16
CP000124_0999 1/1 213 278 .. 1 87 [] 56.0 1.5e-15
CP000124_1242 1/1 219 277 .. 1 87 [] 54.5 3.9e-15
CP000124_1773 1/1 45 110 .. 1 87 [] 52.5 1.5e-14
CP000124_0945 1/1 235 300 .. 1 87 [] 50.9 4e-14
CP000124_0247 1/1 238 304 .. 1 87 [] 49.7 8.9e-14
CP000124_2710 1/1 630 700 .. 1 87 [] 42.1 1.3e-11
CP000124_0344 1/1 525 597 .. 1 87 [] 41.3 2.1e-11
CP000124_2477 1/1 227 286 .. 1 87 [] 39.7 6e-11
CP000124_0632 1/1 432 494 .. 1 81 [. 34.4 1.9e-09
CP000124_0374 1/1 201 270 .. 1 87 [] 27.1 2.3e-07

Alignments of top-scoring domains:
CP000124_1606: domain 1 of 1, from 206 to 272: score 92.0, E = 9e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+an+sHEL+TPLt+++g++e+++e +ls+++r
CP000124_1 206 MRRDFVANVSHELKTPLTVLSGFLETMRE---------LPLSDDER- 242

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yle ++++a r+++++ dlL l+++e +
CP000124_1 243 ----------ARYLELMEQQASRMRHIVTDLLVLAKLEGE 272

CP000124_2196: domain 1 of 1, from 493 to 558: score 78.0, E = 8.5e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak f+a++sHE+RTPL+++ g++el+ + ++l +eq
CP000124_2 493 AKVAFFASMSHEIRTPLSSLVGNIELIAR---------GPLAPEQ-- 528

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++ ++ +a+ l +++nd+Ld+s+i+ g
CP000124_2 529 ----------QARVKAMETSARGLMQIVNDVLDFSKIDVG 558

CP000124_1383: domain 1 of 1, from 677 to 748: score 66.0, E = 2.1e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +l+++sH+LRTPLtaI g++++L + + g t +++ r
CP000124_1 677 LRNSLLSAISHDLRTPLTAIVGLSSMLAN-----ARGATREGSPARE 718

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+++ i++ea r+ ++ +lLd++r++ag
CP000124_1 719 ----------DELVDAIHDEALRMTGIVTNLLDMARLQAG 748

CP000124_0959: domain 1 of 1, from 583 to 648: score 63.2, E = 1.3e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +f+a+++H+++TPL+++r+ ae +l+ +e +++
CP000124_0 583 LQKRFIADAAHQMKTPLAGLRTQAEFALR---------HEVNADV-- 618

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ le i ++e+ rL+ +lL l+r+e+
CP000124_0 619 ----------ARSLEQIATSSEQAARLVTQLLALARAENR 648

CP000124_2730: domain 1 of 1, from 167 to 235: score 61.8, E = 3.3e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++nl+HE+++PL +Irg+a+lL+ el +e+ +++
CP000124_2 167 VNKQLIRNLAHEIKNPLGGIRGAAQLLEFEL-------GERERDEL- 205

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
rey+++i++e++rl+ L+++lL+ r +
CP000124_2 206 ----------REYTQVIIKESDRLQTLVDRLLEPHRHPHI 235

CP000124_0202: domain 1 of 1, from 239 to 304: score 60.0, E = 1.1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a+++H+LRTPLtaI+++ae + +++++q+
CP000124_0 239 AQRKFIADAAHQLRTPLTAIKLHAEQAAV----------ARDPQQA- 274

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ ++++a+r rL n+lL l+r+e g
CP000124_0 275 ----------LTAVRELRSAADRAVRLSNQLLSLARAEPG 304

CP000124_0999: domain 1 of 1, from 213 to 278: score 56.0, E = 1.5e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+a++ a+l + ++++ r
CP000124_0 213 TQKAFVADAAHELRTPLAAVQIQAQLVAR----------AQDDVSR- 248

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re++ +++ + r rL ++lL l+r+e g
CP000124_0 249 ----------REAIVDLQSGVTRATRLAEQLLALARAEPG 278

CP000124_1242: domain 1 of 1, from 219 to 277: score 54.5, E = 3.9e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +la+++H+LRTPL+ +r+ ae++ +
CP000124_1 219 DRAVMLAGVAHDLRTPLARMRLRAEMMDD------------------ 247

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + + r+++++ ++++++L ++ +a
CP000124_1 248 ----------ARLRDGVVRDVDSMTHIVDQFLVFAHGDAD 277

CP000124_1773: domain 1 of 1, from 45 to 110: score 52.5, E = 1.5e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + la++sHELR P++++++++el + + l +eq
CP000124_1 45 ASRGSLATASHELRAPVNGMLALVELVRQ---------GLLAPEQ-- 80

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l +++++++l r +nd+Ld + ieag
CP000124_1 81 ----------QRLLGLVQDSGQSLARVLNDILDHASIEAG 110

CP000124_0945: domain 1 of 1, from 235 to 300: score 50.9, E = 4e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ fl ++sHELRTPL aI g +e+Ll+ ++se
CP000124_0 235 AKNAFLGMVSHELRTPLQAICGSIEVLLA---------RPQSEAN-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++++++a +l++++ dl d+ ++++
CP000124_0 271 ----------MKTIKRLQNSAASLEAQVKDLTDYIKLRST 300

CP000124_0247: domain 1 of 1, from 238 to 304: score 49.7, E = 8.9e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+a+++H+LRTP+++I + ++ ++ e ++ +
CP000124_0 238 TQRRFIADAAHQLRTPIAVIDTQIQCARQ---------RENGDAAL- 274

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l +++r+++r+ + + lL l+ +ea
CP000124_0 275 ----------AALLASMQRSSRRMADVTDKLLLLAHAEAA 304

CP000124_2710: domain 1 of 1, from 630 to 700: score 42.1, E = 1.3e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++++++HEL++PL+aI y++ l+ l +++ +s+e++
CP000124_2 630 TMGEMASSIAHELNQPLAAINNYCSGTLA-----LVKSGRASPETL- 670

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +le+ ++a r ++ +++++ + ++
CP000124_2 671 ----------APALEKTAQQALRAGMIVKRIREFVKRSEP 700

CP000124_0344: domain 1 of 1, from 525 to 597: score 41.3, E = 2.1e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +e ++ l+HE+++PLt I++ ae L+++l +++ls ++ +
CP000124_0 525 AWGEVARRLAHEIKNPLTPIQLSAERLQMKL------SDKLSQPD-A 564

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ L ++ ti +++ + r+++d++d++r
CP000124_0 565 DVL-------KRGATTIVNQVAAMKRMVDDFRDYARTPPA 597

CP000124_2477: domain 1 of 1, from 227 to 286: score 39.7, E = 6e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +la++sH+LRTPL+ +r+ +e+ +
CP000124_2 227 DRALMLAGISHDLRTPLARLRLETEMSPSD----------------- 256

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + +++e+++r+i + d++r +
CP000124_2 257 ----------QATKDAMVDDIEQMDRIIAAFIDYARPAQR 286

CP000124_0632: domain 1 of 1, from 432 to 494: score 34.4, E = 1.9e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++a++ HEL++PL+a+r +++ + +++e+ ++
CP000124_0 432 ALGQMAAGITHELNQPLAALRSFSDNTRV--------LLDRGEQAAA 470

peLRledpeyreyletilreaerllrLindlLdl<-*
re le i +er+ ++ n+l +
CP000124_0 471 ----------RENLEAIAALTERMGKITNQLKLF 494

CP000124_0374: domain 1 of 1, from 201 to 270: score 27.1, E = 2.3e-07
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ +a+++HE+ TPL++I +++e L+e a +t+++
CP000124_0 201 ALGVQAATVAHEMGTPLSTIAMLTEELRE------AARTDAGLAR-- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y l++++++ ++ + + +l+ + +
CP000124_0 240 ---------YDADLKVLEEQMSQCTSALARLRSRASERPS 270


Histogram of all scores:
score obs exp (one = represents 13 sequences)
----- --- ---
-15 1 0|=
-14 7 0|=
-13 36 2|*==
-12 121 85|======*===
-11 263 442|===================== *
-10 518 821|======================================== *
-9 706 848|======================================================= *
-8 718 635|================================================*=======
-7 508 400|==============================*=========
-6 355 230|=================*==========
-5 213 126|=========*=======
-4 114 67|=====*===
-3 77 35|==*===
-2 41 18|=*==
-1 20 9|*=
0 11 5|*
1 4 2|*
2 2 1|*
3 0 0|
> 4 21 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 513.7761
P(chi-square) = 0

Total sequences searched: 3736

Whole sequence top hits:
tophits_s report:
Total hits: 16
Satisfying E cutoff: 16
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 16
Satisfying E cutoff: 16
Total memory: 27K


Acknowledgements:

This research is funded by:

Developed by: