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2 accessions found for Burkholderia pseudomallei 1710b  

Data for CP000125  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000125.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
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Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000125_1625 CDS_1988651-1985685 96.1 4.4e-27 1
CP000125_1377 CDS_1685434-1683125 75.9 2.4e-21 1
CP000125_0029 CDS_57406-55259 67.8 4.7e-19 1
CP000125_1103 CDS_1382051-1383361 59.0 1.4e-16 1
CP000125_2199 CDS_2698062-2694781 57.8 3.2e-16 1
CP000125_2184 CDS_2679456-2680757 57.1 5e-16 1
CP000125_2270 CDS_2767546-2769051 55.8 1.1e-15 1
CP000125_2250 CDS_2749495-2748167 47.4 2.8e-13 1
CP000125_0382 CDS_543346-541175 46.5 4.9e-13 1
CP000125_0489 CDS_675044-672876 45.0 1.3e-12 1
CP000125_0709 CDS_944960-943884 38.0 1.3e-10 2
CP000125_1570 CDS_1908805-1910736 31.6 8.4e-09 1
CP000125_0875 CDS_1137136-1137984 29.0 4.6e-08 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000125_1625 1/1 506 571 .. 1 87 [] 96.1 4.4e-27
CP000125_1377 1/1 394 459 .. 1 87 [] 75.9 2.4e-21
CP000125_0029 1/1 493 559 .. 1 87 [] 67.8 4.7e-19
CP000125_1103 1/1 194 260 .. 1 87 [] 59.0 1.4e-16
CP000125_2199 1/1 867 932 .. 1 87 [] 57.8 3.2e-16
CP000125_2184 1/1 218 283 .. 1 87 [] 57.1 5e-16
CP000125_2270 1/1 240 305 .. 1 87 [] 55.8 1.1e-15
CP000125_2250 1/1 207 272 .. 1 87 [] 47.4 2.8e-13
CP000125_0382 1/1 490 558 .. 1 87 [] 46.5 4.9e-13
CP000125_0489 1/1 499 564 .. 1 87 [] 45.0 1.3e-12
CP000125_1570 1/1 407 475 .. 1 87 [] 31.6 8.4e-09
CP000125_0875 1/1 50 117 .. 1 87 [] 29.0 4.6e-08

Alignments of top-scoring domains:
CP000125_1625: domain 1 of 1, from 506 to 571: score 96.1, E = 4.4e-27
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL+aI+g++elL++ ++lse+q
CP000125_1 506 AKSTFLATMSHEIRTPLNAIIGNLELLRR---------SPLSEQQ-- 541

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e l++++++++ ll++ind+Ldls+ e+g
CP000125_1 542 ----------SERLHVVESCSNALLHIINDILDLSKVESG 571

CP000125_1377: domain 1 of 1, from 394 to 459: score 75.9, E = 2.4e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+e+la++sHELRTPL++I g +e+L++ + ++ q
CP000125_1 394 LKDELLATVSHELRTPLNVIYGWIEVLRN---------PVDGALQ-- 429

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ i+r+a++l+r++ d+Ld s + +g
CP000125_1 430 ----------QQAIDAIDRSARSLSRMVGDILDASSLATG 459

CP000125_0029: domain 1 of 1, from 493 to 559: score 67.8, E = 4.7e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f +nl+H++RTPLt +++ a+++l ++++++
CP000125_0 493 RLSQFSSNLAHDMRTPLTNLLAEAQVALS---------KPRTADE-- 528

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr+ +e+ ++e +rl+r+i+d+L l+r ++
CP000125_0 529 ---------YRDVIESSIDEYQRLSRMIEDMLFLARSDNA 559

CP000125_1103: domain 1 of 1, from 194 to 260: score 59.0, E = 1.4e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ e ++l+H++RTPLt +++ a+++l + +s ++
CP000125_1 194 RLKEYSSDLAHDIRTPLTNLLAEAQVALS---------QRRSVDE-- 229

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr+ +e+ +e +rl r+++d+L l+r++
CP000125_1 230 ---------YRQVIESSVEEYQRLARMVDDMLFLARADGH 260

CP000125_2199: domain 1 of 1, from 867 to 932: score 57.8, E = 3.2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ f+a+++HELRTP+ +++ ++lL++ ++s+++r
CP000125_2 867 LQRHFIADAAHELRTPIMGLSIQTQLLQR----------TASADER- 902

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l i+ + rl++L ++lL+l+r+e +
CP000125_2 903 ----------ARILAQIQAGTTRLSHLAEQLLTLARLEPE 932

CP000125_2184: domain 1 of 1, from 218 to 283: score 57.1, E = 5e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++ ++sHELRTPL+ +r+++e L+e + s+ +
CP000125_2 218 TQRDLTNGISHELRTPLARVRFALESLRE----------PGSAAE-- 252

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ ++++i++++ l++Li+ L+++r+e
CP000125_2 253 ---------YQNAIDSIEQDVSELDELIDMSLTYARLEYS 283

CP000125_2270: domain 1 of 1, from 240 to 305: score 55.8, E = 1.1e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a+++H+L+TPL+a ++ +el+l+ ++ e +
CP000125_2 240 ARRRFFADAAHQLKTPLAAAQAGVELALR----------PAERERV- 275

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l+++ ++++ +++++lL lsr+e+
CP000125_2 276 ----------SVHLRRVNGAVRQAAKIVQQLLSLSRLESD 305

CP000125_2250: domain 1 of 1, from 207 to 272: score 47.4, E = 2.8e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++e++ ++sHEL+TPL+ + + + lL ++++e
CP000125_2 207 QQREMMHGISHELKTPLARLEFGLALLSS---------PDAPERM-- 242

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re ++r+++ l++L+ +lL++ r+e+g
CP000125_2 243 ----------RERQAALRRDVRELDELVTELLTIGRLEQG 272

CP000125_0382: domain 1 of 1, from 490 to 558: score 46.5, E = 4.9e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+ +sH+L PL a+ g ++lL++++ + l++
CP000125_0 490 DLEQFAYVASHDLQEPLRAVAGPLQLLQRRYQ------GQLDARA-- 528

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e++ + + a r+++Li+dlL +sr +
CP000125_0 529 ----------DEFIGHAVDGATRMQSLIDDLLSYSRVGRL 558

CP000125_0489: domain 1 of 1, from 499 to 564: score 45.0, E = 1.3e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + f+an +HELRTP++a ++ ++ L + e+++e +
CP000125_0 499 AERSFTANSAHELRTPIAAALAQTQRLIA----------EAPAEPL- 534

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re ++++ +++ l+r ++l++l+++e g
CP000125_0 535 ----------RERARRVEGALHTLSRVSEQLMQLAKAEDG 564

CP000125_1570: domain 1 of 1, from 407 to 475: score 31.6, E = 8.4e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++a++ HEL++PL+aI+++++ + + + +s++
CP000125_1 407 ALGQMAAGITHELNQPLAAIMTLSSNAVRMAA------LGRSADL-- 445

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ le + + a r+ +++ + ++r e+
CP000125_1 446 ----------TRNLELVNDLAGRMGKIVAHMKGFARHESV 475

CP000125_0875: domain 1 of 1, from 50 to 117: score 29.0, E = 4.6e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ l+ +sH+LR PL+a+ a +L++ + ++s+e +
CP000125_0 50 VRDHALSVASHDLRSPLNAMHSWAYVLER--------RLTASDENL- 87

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+ i+ +e+ +L++ d r+e+
CP000125_0 88 ----------ARALDGIRIGIEQQTKLLETTIDAPRAETR 117


Histogram of all scores:
score obs exp (one = represents 9 sequences)
----- --- ---
-15 1 0|=
-14 8 0|=
-13 40 1|*====
-12 71 59|======*=
-11 219 309|========================= *
-10 391 574|============================================ *
-9 476 592|===================================================== *
-8 474 443|=================================================*===
-7 369 279|==============================*==========
-6 226 161|=================*========
-5 148 88|=========*=======
-4 82 47|=====*====
-3 35 24|==*=
-2 23 13|=*=
-1 15 6|*=
0 7 3|*
1 4 1|*
2 2 0|=
> 3 20 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 253.8744
P(chi-square) = 0

Total sequences searched: 2611

Whole sequence top hits:
tophits_s report:
Total hits: 13
Satisfying E cutoff: 13
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 12
Satisfying E cutoff: 12
Total memory: 25K


Acknowledgements:

This research is funded by:

Developed by: