Acidobacteria Actinobacteria Alphaproteobacteria
Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria
Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
Search:
264 projects found  

2 accessions found for   

Data for CP000127  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000127.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000127_1216 CDS_1403259-1407758 93.5 2.8e-26 1
CP000127_2304 CDS_2750889-2749576 82.3 4.1e-23 1
CP000127_1674 CDS_1975322-1977478 71.3 5.4e-20 1
CP000127_1544 CDS_1816014-1814524 65.0 3.2e-18 1
CP000127_1335 CDS_1550310-1553126 61.1 4.2e-17 1
CP000127_2349 CDS_2795124-2796623 59.8 9.6e-17 1
CP000127_0680 CDS_780027-781685 59.7 1e-16 1
CP000127_1522 CDS_1784674-1781006 55.1 2.1e-15 1
CP000127_0638 CDS_733591-732212 55.0 2.2e-15 1
CP000127_0740 CDS_855852-857327 50.8 3.4e-14 1
CP000127_2906 CDS_3411288-3413426 49.7 7e-14 2
CP000127_1621 CDS_1906186-1907292 49.1 1e-13 1
CP000127_1618 CDS_1902839-1904500 37.5 2.1e-10 1
CP000127_1114 CDS_1278348-1277101 35.1 9.6e-10 1
CP000127_2351 CDS_2797081-2798751 33.2 3.3e-09 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000127_1216 1/1 272 337 .. 1 87 [] 93.5 2.8e-26
CP000127_2304 1/1 200 267 .. 1 87 [] 82.3 4.1e-23
CP000127_1674 1/1 501 569 .. 1 87 [] 71.3 5.4e-20
CP000127_1544 1/1 265 330 .. 1 87 [] 65.0 3.2e-18
CP000127_1335 1/1 574 640 .. 1 87 [] 61.1 4.2e-17
CP000127_2349 1/1 276 344 .. 1 87 [] 59.8 9.6e-17
CP000127_0680 1/1 325 391 .. 1 87 [] 59.7 1e-16
CP000127_1522 1/1 858 924 .. 1 87 [] 55.1 2.1e-15
CP000127_0638 1/1 232 296 .. 1 87 [] 55.0 2.2e-15
CP000127_0740 1/1 262 330 .. 1 87 [] 50.8 3.4e-14
CP000127_1621 1/1 143 211 .. 1 87 [] 49.1 1e-13
CP000127_2906 1/2 477 549 .. 1 87 [] 48.8 1.3e-13
CP000127_1618 1/1 321 391 .. 1 87 [] 37.5 2.1e-10
CP000127_1114 1/1 172 238 .. 1 87 [] 35.1 9.6e-10
CP000127_2351 1/1 334 406 .. 1 87 [] 33.2 3.3e-09

Alignments of top-scoring domains:
CP000127_1216: domain 1 of 1, from 272 to 337: score 93.5, E = 2.8e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ef+an+sHE+RTPL++++g +elL++ l+++q
CP000127_1 272 IKGEFAANVSHEIRTPLNGVIGILELLKN---------MGLNPKQ-- 307

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
rey++ + +++e ll+Li ++Ld+srie+g
CP000127_1 308 ----------REYVQAACNSGETLLELIGNILDFSRIESG 337

CP000127_2304: domain 1 of 1, from 200 to 267: score 82.3, E = 4.1e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPLt++rgy+e+L+++ + ++e
CP000127_2 200 MRRDFIASVSHELRTPLTVLRGYLEILEKG--------KNVGSES-- 236

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + ++t+ +++ r+++L++dlL lsr+e+
CP000127_2 237 ---------WNRSFKTMGEQVGRMQHLVEDLLMLSRLESR 267

CP000127_1674: domain 1 of 1, from 501 to 569: score 71.3, E = 5.4e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f ++sH+LR PL +I g++++Lle+++ ++l++e
CP000127_1 501 ELEAFSYSVSHDLRAPLRSIDGFSQALLEDYE------DKLDSEG-- 539

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl++++ +++r+ +Li+dlL+lsri
CP000127_1 540 ----------QDYLQRVRAATQRMGKLIDDLLQLSRISRV 569

CP000127_1544: domain 1 of 1, from 265 to 330: score 65.0, E = 3.2e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +e++a+++HELR+PL++I++ ++ L++ + +++q
CP000127_1 265 AVGELAASIAHELRNPLAGILMSCSNLRK---------EISDPDQ-- 300

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l+ i e++rl rL+n+lLd ++ +
CP000127_1 301 ----------AQRLDLIGAELKRLTRLLNNLLDQAKHTPQ 330

CP000127_1335: domain 1 of 1, from 574 to 640: score 61.1, E = 4.2e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+efla+l HELR+PL+ +r ++ +++ +++e +
CP000127_1 574 KKDEFLATLTHELRNPLAPMRNALYVIKS---------NSANAEAQ- 610

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e i+r++ ++ rLi+dl+d sri g
CP000127_1 611 ----------THAHELIERQISQIVRLIDDLMDVSRITRG 640

CP000127_2349: domain 1 of 1, from 276 to 344: score 59.8, E = 9.6e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sH+LR PL +I+g++ +L+ + t + eq+
CP000127_2 276 ELERFIYTVSHDLRSPLITIQGFSGMLKQSF-------TQHNQEQI- 314

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e + +i+ +a ++ L++dlL+lsri+
CP000127_2 315 ----------LEDIGRIQAAAGKMQLLLDDLLELSRIGRL 344

CP000127_0680: domain 1 of 1, from 325 to 391: score 59.7, E = 1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++++a+++HE+R+PL aI+ +++lL+e +++ls +
CP000127_0 325 SLGRLTASIAHEIRNPLGAISHASQLLRE--------SSTLSQSE-- 361

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++le+il+ + ++ ++L+lsr ++
CP000127_0 362 ----------QRLLEIILNHCTGVNGIVKNVLQLSRRQQH 391

CP000127_1522: domain 1 of 1, from 858 to 924: score 55.1, E = 2.1e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k+efla l HELR+PL++I ++elL +e+ +++++++
CP000127_1 858 QKDEFLALLGHELRNPLAVIFNTTELLIRESG------ATRDAQHG- 897

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ i r+a++l rL++dlL l+r +g
CP000127_1 898 -------------IALIGRQAKHLGRLVDDLLNLTRVNSG 924

CP000127_0638: domain 1 of 1, from 232 to 296: score 55.0, E = 2.2e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++l+++sHELR PL+ ++ ++ l + ++ ++++ +
CP000127_0 232 SQKQLLSDVSHELRSPLARLQVALGLVRQRQ-------QHQTNAE-- 269

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l++i++eaerl++Li +lL l+r+e++
CP000127_0 270 -------------LDRIEHEAERLNELIGQLLSLTRLESN 296

CP000127_0740: domain 1 of 1, from 262 to 330: score 50.8, E = 3.4e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k +fl+++sHEL+TPL+a+r +elL +++ + ls++q
CP000127_0 262 TKVKFLRHVSHELKTPLAALREGSELLCDQVI------GRLSAQQ-- 300

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e +++++ + rl++Li+d+L + ++++
CP000127_0 301 ----------LEVARILRSNSLRLQKLIEDMLRFNLAGTN 330

CP000127_1621: domain 1 of 1, from 143 to 211: score 49.1, E = 1e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ +sH+L PL ++ ya+lL +++ + l+++
CP000127_1 143 ELEQFAYVASHDLQEPLRMVSSYAQLLARRY------RNQLDSDA-- 181

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e++e + + a r+++LindlL +sr+++
CP000127_1 182 ----------DEFIEFMVDGATRMQALINDLLAYSRAGTK 211

CP000127_2906: domain 1 of 2, from 477 to 549: score 48.8, E = 1.3e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +e ++ l+HE+++PLt I++ ae L++++ l+ +q++
CP000127_2 477 AWGEVARRLAHEIKNPLTPIQLSAERLRRKY------LKLLPTDQIQ 517

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
p ++++ti+ ++e + +++n + +++r a
CP000127_2 518 PL--------DRLTHTIIAQVEAMKEMVNAFSEYARNPAL 549

CP000127_1618: domain 1 of 1, from 321 to 391: score 37.5, E = 2.1e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++a ++HEL++PL aI +y++++l+ l +++++++++
CP000127_1 321 TLGEMAAQIAHELNQPLGAITTYSDICLRTL-------EPQTSKHQP 360

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++le i +aer ++i+ l+ l ++
CP000127_1 361 ---------LRDILEEIATQAERGGKIIRHLRNLIHKKEQ 391

CP000127_1114: domain 1 of 1, from 172 to 238: score 35.1, E = 9.6e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++++l+ + H++R L+aI g++ +L t+++ e
CP000127_1 172 ARGKLLREATHDIRGGLSAIEGASAILNI---------TKKPHES-- 207

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l+++ +++ ++++ lL+lsr+e+g
CP000127_1 208 ---------FTHILDILNAGINSVKEMLDSLLELSRLESG 238

CP000127_2351: domain 1 of 1, from 334 to 406: score 33.2, E = 3.3e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkv.lagdtelseeqr
++ef ++l+HE ++P+ta++ y+ +++ ag ++ + +++
CP000127_2 334 TLGEFGSTLAHEVNQPITAVINYVRACQQ----IiMAGKEPTTLQTI 376

lpeLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+ ++ ea+r ++i l++++r ++
CP000127_2 377 -----------HELMDKTAGEADRAASIIHHLREFARTGEL 406


Histogram of all scores:
score obs exp (one = represents 10 sequences)
----- --- ---
-14 3 0|=
-13 29 2|*==
-12 130 67|======*======
-11 273 352|============================ *
-10 457 654|============================================== *
-9 568 675|========================================================= *
-8 501 505|==================================================*
-7 370 318|===============================*=====
-6 259 183|==================*=======
-5 153 100|=========*======
-4 111 53|=====*======
-3 43 28|==*==
-2 32 14|=*==
-1 9 7|*
0 9 4|*
1 4 2|*
2 1 1|*
3 2 0|=
> 4 20 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 305.5854
P(chi-square) = 0

Total sequences searched: 2976

Whole sequence top hits:
tophits_s report:
Total hits: 15
Satisfying E cutoff: 15
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 15
Satisfying E cutoff: 15
Total memory: 26K


Acknowledgements:

This research is funded by:

Developed by: