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Thermotogae
Classification of phyla is from NCBI page
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76 projects found  

3 accessions found for Burkholderia sp. 383  

Data for CP000152  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000152.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000152_2873 CDS_3260471-3257460 91.3 1.2e-25 1
CP000152_2087 CDS_2396847-2395255 88.9 5.9e-25 1
CP000152_2876 CDS_3265143-3262045 80.7 1.2e-22 1
CP000152_2423 CDS_2765535-2764111 70.8 8e-20 1
CP000152_1637 CDS_1866317-1864299 70.3 1.1e-19 1
CP000152_1727 CDS_1968420-1969859 67.4 7.1e-19 1
CP000152_2374 CDS_2712783-2711077 66.1 1.7e-18 1
CP000152_1760 CDS_2005948-2004515 60.6 6.1e-17 1
CP000152_2763 CDS_3136863-3138281 60.5 6.7e-17 1
CP000152_0750 CDS_849771-850901 59.3 1.5e-16 1
CP000152_0910 CDS_1024359-1025810 57.3 5.2e-16 1
CP000152_0764 CDS_873702-872317 53.2 7.6e-15 1
CP000152_2882 CDS_3269897-3271717 52.6 1.1e-14 1
CP000152_3044 CDS_3447356-3448441 46.6 5.8e-13 1
CP000152_2238 CDS_2567299-2568078 43.6 4.1e-12 1
CP000152_1559 CDS_1768694-1770736 41.6 1.5e-11 1
CP000152_0306 CDS_331503-329620 31.9 8.4e-09 1
CP000152_2521 CDS_2874237-2875658 30.8 1.7e-08 1
CP000152_0904 CDS_1018258-1016912 29.6 3.6e-08 1
CP000152_2725 CDS_3092228-3090876 28.7 6.7e-08 1
CP000152_0398 CDS_439541-440863 27.8 1.2e-07 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000152_2873 1/1 520 585 .. 1 87 [] 91.3 1.2e-25
CP000152_2087 1/1 150 217 .. 1 87 [] 88.9 5.9e-25
CP000152_2876 1/1 521 586 .. 1 87 [] 80.7 1.2e-22
CP000152_2423 1/1 242 308 .. 1 87 [] 70.8 8e-20
CP000152_1637 1/1 294 359 .. 1 87 [] 70.3 1.1e-19
CP000152_1727 1/1 234 301 .. 1 87 [] 67.4 7.1e-19
CP000152_2374 1/1 337 404 .. 1 87 [] 66.1 1.7e-18
CP000152_1760 1/1 249 314 .. 1 87 [] 60.6 6.1e-17
CP000152_2763 1/1 247 313 .. 1 87 [] 60.5 6.7e-17
CP000152_0750 1/1 161 226 .. 1 87 [] 59.3 1.5e-16
CP000152_0910 1/1 255 320 .. 1 87 [] 57.3 5.2e-16
CP000152_0764 1/1 236 301 .. 1 87 [] 53.2 7.6e-15
CP000152_2882 1/1 235 300 .. 1 87 [] 52.6 1.1e-14
CP000152_3044 1/1 134 198 .. 1 87 [] 46.6 5.8e-13
CP000152_2238 1/1 28 95 .. 1 87 [] 43.6 4.1e-12
CP000152_1559 1/1 442 499 .. 1 77 [. 41.6 1.5e-11
CP000152_0306 1/1 398 466 .. 1 87 [] 31.9 8.4e-09
CP000152_2521 1/1 241 298 .. 1 79 [. 30.8 1.7e-08
CP000152_0904 1/1 229 280 .. 1 80 [. 29.6 3.6e-08
CP000152_2725 1/1 247 305 .. 1 87 [] 28.7 6.7e-08
CP000152_0398 1/1 231 272 .. 1 62 [. 27.8 1.2e-07

Alignments of top-scoring domains:
CP000152_2873: domain 1 of 1, from 520 to 585: score 91.3, E = 1.2e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL+aI+g++el+ + +el++ +
CP000152_2 520 AKSTFLATMSHEIRTPLNAIIGNLELMGR---------AELPPTE-- 555

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l+ti ++++ ll++ind+Ldls++e++
CP000152_2 556 ----------QRRLKTIVSSSDALLNIINDVLDLSKAESN 585

CP000152_2087: domain 1 of 1, from 150 to 217: score 88.9, E = 5.9e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fl+++sHELR PL+aI+g+a+l+ +++ ++ ++ q
CP000152_2 150 AKSDFLSSMSHELRSPLNAILGFAQLMATDS-------PPPTPSQ-- 187

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++ ilr++ +ll+Lind+Ldl++i+ag
CP000152_2 188 ----------QASIDQILRAGWHLLELINDVLDLAKIDAG 217

CP000152_2876: domain 1 of 1, from 521 to 586: score 80.7, E = 1.2e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++ HE+RTPL++I+g++elL + ++l++ q
CP000152_2 521 AKSSFLAAITHEIRTPLNVILGNLELLDR---------SALDASQ-- 556

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++t++ +a ll L++d+Ld+s+ieag
CP000152_2 557 ----------HGRVQTLRAAASGLLGLVSDILDFSKIEAG 586

CP000152_2423: domain 1 of 1, from 242 to 308: score 70.8, E = 8e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f +nl+H++RTPLt ++++a++ l +++s+e+
CP000152_2 242 RLSQFSSNLAHDMRTPLTNLQAAAQVVLS---------QPRSAEE-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr +e+ ++e +rl+r+i+d+L l+r e+
CP000152_2 278 ---------YRNVIESSIDEYQRLSRMIEDMLFLARSEQA 308

CP000152_1637: domain 1 of 1, from 294 to 359: score 70.3, E = 1.1e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+e+la++sHELRTPL++I g +e+L++ +
CP000152_1 294 LKDELLATVSHELRTPLNVIYGWVEVLRN---------VDGQGLA-- 329

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ i+r+a++l++++ dlLd s + +g
CP000152_1 330 ----------QQAVDAIDRSARSLSHMVADLLDASSLATG 359

CP000152_1727: domain 1 of 1, from 234 to 301: score 67.4, E = 7.1e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f a+++HELRTP++ ++g ++++l+ + +++ e +
CP000152_1 234 RLEAFNADVAHELRTPISILIGQTQVALT--------SRDRTVERM- 271

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l++ l+e erl+ +ind+L lsr + g
CP000152_1 272 ----------QQTLQSNLEEFERLRVIINDMLFLSRSDRG 301

CP000152_2374: domain 1 of 1, from 337 to 404: score 66.1, E = 1.7e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ +la++sH+L+TPLtaIrg+ae+L++ +e+ ++ ++
CP000152_2 337 MRNALLAAVSHDLKTPLTAIRGLAETLER---------PERLADGQP 374

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + i+++ae l L+ +lLdl+r++++
CP000152_2 375 ----------AALAHGIRNQAEALHGLVVNLLDLARMQSE 404

CP000152_1760: domain 1 of 1, from 249 to 314: score 60.6, E = 6.1e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a+++H+L+TPL+a+++ +el+l+ ++ +
CP000152_1 249 ARRRFFADAAHQLKTPLAAVQAGVELALR---------PDEQPRA-- 284

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l+++ ++++ +++++lL lsr+++
CP000152_1 285 ----------NGHLRRANGAVRQAAKIVQQLLSLSRLDSD 314

CP000152_2763: domain 1 of 1, from 247 to 313: score 60.5, E = 6.7e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f ++l+H++RTPL+ ++ +++ l +++ e+
CP000152_2 247 RLSQFSSDLAHDMRTPLANVISSSQVTLS---------RARTTEE-- 282

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ ++++ ++e erl+r+i+++L l+r ++
CP000152_2 283 ---------YEALIDSNIEECERLQRMIENMLFLARTDNA 313

CP000152_0750: domain 1 of 1, from 161 to 226: score 59.3, E = 1.5e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++ ++sHELRTPL+ +r+++e+L+e + s+ +
CP000152_0 161 AQRDLTNGISHELRTPLARVRFALEMLRE----------PGSAAE-- 195

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ +le+i +++ l++Li+ L+++r+e
CP000152_0 196 ---------YQGALESIAQDVTELEELIDMSLTYARLEYS 226

CP000152_0910: domain 1 of 1, from 255 to 320: score 57.3, E = 5.2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + +l HE++ PL+aI+g+aelL+e e++ r
CP000152_0 255 YVETYIHTLTHEMKSPLAAISGAAELLQE----------EMPVANR- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+++e i+r+a rl+++i+ lL l+ e+
CP000152_0 291 ----------RRFTENIRRQAGRLEQMIRKLLALAEVEQK 320

CP000152_0764: domain 1 of 1, from 236 to 301: score 53.2, E = 7.6e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ f+a+++HELRTP+ +++ ++lL++ + ++e+r
CP000152_0 236 LQRHFIADAAHELRTPIMGLSIQSQLLRR----------ASTAEER- 271

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l i+ + rl +L ++lL+l+r+e
CP000152_0 272 ----------EHILAQIHAGTTRLGHLAEQLLTLARLEPD 301

CP000152_2882: domain 1 of 1, from 235 to 300: score 52.6, E = 1.1e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ fl ++sHELRTPL aI g +e+Ll+ ++s+
CP000152_2 235 AKNAFLGMVSHELRTPLQAICGSVEILLA---------RPQSDAN-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++++++a +l++L+ dl d+ ++++
CP000152_2 271 ----------LKTIRRLQNSALSLEALVKDLTDYIKLRST 300

CP000152_3044: domain 1 of 1, from 134 to 198: score 46.6, E = 5.8e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + a+++HELRTP+t++rg ++ L e+++ + +e q
CP000152_3 134 EQAIWNAAIAHELRTPVTVLRGRLQGLAEGVF-------KPDEAQ-- 171

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++l ++e l rLi+dl+ s ++ g
CP000152_3 172 -------------FRSLLAQVEGLTRLIEDLRVVSLADGG 198

CP000152_2238: domain 1 of 1, from 28 to 95: score 43.6, E = 4.1e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ l+++sH+LR PL+a+ a +L+++l +++++
CP000152_2 28 LRDQALSTASHDLRSPLNAMHSWAYVLERQL-------ANADPNL-- 65

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l i+ +++ +Li+d+Ld r+++
CP000152_2 66 ----------QRALAGIRTGIDQQVALIDDVLDAPRADTR 95

CP000152_1559: domain 1 of 1, from 442 to 499: score 41.6, E = 1.5e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++la++sHELRTPL++I ++a+ L d+ s++ +
CP000152_1 442 EQRQLLATVSHELRTPLAVIDATAQNLDL--------DDSGSDPLT- 479

peLRledpeyreyletilreaerllrLind<-*
++ilr+++rl Lind
CP000152_1 480 ----------SSRYQKILRATQRLTVLIND 499

CP000152_0306: domain 1 of 1, from 398 to 466: score 31.9, E = 8.4e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++a+l HEL++PL aIr++++ ++++++ ++++
CP000152_0 398 VLGQMAAGLTHELNQPLVAIRTLCDNARTFFE------RGQPAPA-- 436

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i + ++++ L +l +++r
CP000152_0 437 ----------LANLERIGKLVDSMAVLTGELKTFARKPDV 466

CP000152_2521: domain 1 of 1, from 241 to 298: score 30.8, E = 1.7e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a+++H++RTPL+ + + +elL ++ ++ +
CP000152_2 241 AMQRFIADAAHQMRTPLARLDAQIELLDG---------EADPARH-- 276

peLRledpeyreyletilreaerllrLindlL<-*
+ l+ ++ rL +lL
CP000152_2 277 ----------AARLDALRATCSDVGRLTGQLL 298

CP000152_0904: domain 1 of 1, from 229 to 280: score 29.6, E = 3.6e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+s +la++sH++RTPLt +r+++ ++l
CP000152_0 229 TRSLMLAGVSHDIRTPLTKLRLAIAMALP------------------ 257

peLRledpeyreyletilreaerllrLindlLd<-*
r + + ++e+ l++i+ +L+
CP000152_0 258 ----------RGTHDALTTSTEHYLDQIDTILQ 280

CP000152_2725: domain 1 of 1, from 247 to 305: score 28.7, E = 6.7e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++fla+++HEL TPLt +rg +el + q
CP000152_2 247 VQQQFLADAAHELQTPLTLVRGQIELQPD-------------IRQ-- 278

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+lre++ + r++ +lL l+ +
CP000152_2 279 -------------KALLLREIDLMARQVKQLLHLAEVSEA 305

CP000152_0398: domain 1 of 1, from 231 to 272: score 27.8, E = 1.2e-07
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + la++sH+L TP+t +r+ a+++++ ++++++ r
CP000152_0 231 ERMQILASISHDLQTPITRMRLRADMMED---------DAQGAKLR- 267

peLRledpeyreyle<-*
++++e
CP000152_0 268 ----------QDLIE 272


Histogram of all scores:
score obs exp (one = represents 12 sequences)
----- --- ---
-14 4 0|=
-13 22 2|*=
-12 98 72|=====*===
-11 267 376|======================= *
-10 512 697|=========================================== *
-9 671 720|======================================================== *
-8 590 539|============================================*=====
-7 408 340|============================*=====
-6 259 195|================*=====
-5 149 107|========*====
-4 79 57|====*==
-3 43 30|==*=
-2 16 15|=*
-1 18 8|*=
0 6 4|*
1 3 2|*
2 3 1|*
> 3 26 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 173.0748
P(chi-square) = 2.746e-31

Total sequences searched: 3174

Whole sequence top hits:
tophits_s report:
Total hits: 21
Satisfying E cutoff: 21
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 21
Satisfying E cutoff: 21
Total memory: 29K


Acknowledgements:

This research is funded by:

Developed by: