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Thermotogae
Classification of phyla is from NCBI page
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39 projects found  

1 accessions found for Synechococcus sp. JA-2-3B'a(2-13)  

Data for CP000240  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000240.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000240_0497 CDS_523083-518503 97.6 1.8e-27 1
CP000240_1598 CDS_1712408-1708080 96.0 5.1e-27 1
CP000240_2354 CDS_2517517-2519619 88.7 6.1e-25 1
CP000240_0962 CDS_1023713-1021950 82.4 3.8e-23 1
CP000240_0027 CDS_37646-34638 79.5 2.5e-22 1
CP000240_1727 CDS_1860257-1856514 76.0 2.4e-21 1
CP000240_2398 CDS_2562273-2564777 75.5 3.4e-21 1
CP000240_2404 CDS_2569874-2568126 75.4 3.5e-21 1
CP000240_0836 CDS_891888-893147 69.1 2.1e-19 1
CP000240_1375 CDS_1478037-1479386 67.6 5.7e-19 1
CP000240_1221 CDS_1297727-1296879 65.2 2.8e-18 1
CP000240_1597 CDS_1708045-1706804 63.0 1.1e-17 1
CP000240_2718 CDS_2893312-2895972 61.7 2.6e-17 1
CP000240_2646 CDS_2814921-2813527 53.4 6e-15 1
CP000240_2713 CDS_2887174-2888088 49.2 9.4e-14 1
CP000240_0940 CDS_1002196-1001414 47.8 2.4e-13 1
CP000240_1847 CDS_1982510-1981377 44.0 2.9e-12 1
CP000240_0693 CDS_728829-727768 34.5 1.4e-09 1
CP000240_1315 CDS_1414633-1413155 32.8 4.2e-09 1
CP000240_1314 CDS_1413045-1412287 28.5 7e-08 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000240_0497 1/1 848 913 .. 1 87 [] 97.6 1.8e-27
CP000240_1598 1/1 815 880 .. 1 87 [] 96.0 5.1e-27
CP000240_2354 1/1 436 504 .. 1 87 [] 88.7 6.1e-25
CP000240_0962 1/1 319 386 .. 1 87 [] 82.4 3.8e-23
CP000240_0027 1/1 752 818 .. 1 87 [] 79.5 2.5e-22
CP000240_1727 1/1 1025 1090 .. 1 87 [] 76.0 2.4e-21
CP000240_2398 1/1 598 663 .. 1 87 [] 75.5 3.4e-21
CP000240_2404 1/1 337 404 .. 1 87 [] 75.4 3.5e-21
CP000240_0836 1/1 192 256 .. 1 87 [] 69.1 2.1e-19
CP000240_1375 1/1 197 263 .. 1 87 [] 67.6 5.7e-19
CP000240_1221 1/1 53 122 .. 1 87 [] 65.2 2.8e-18
CP000240_1597 1/1 187 252 .. 1 87 [] 63.0 1.1e-17
CP000240_2718 1/1 651 716 .. 1 87 [] 61.7 2.6e-17
CP000240_2646 1/1 211 274 .. 1 87 [] 53.4 6e-15
CP000240_2713 1/1 51 126 .. 1 87 [] 49.2 9.4e-14
CP000240_0940 1/1 41 108 .. 1 87 [] 47.8 2.4e-13
CP000240_1847 1/1 147 216 .. 1 87 [] 44.0 2.9e-12
CP000240_0693 1/1 138 205 .. 1 87 [] 34.5 1.4e-09
CP000240_1315 1/1 260 306 .. 1 67 [. 32.8 4.2e-09
CP000240_1314 1/1 30 93 .. 1 87 [] 28.5 7e-08

Alignments of top-scoring domains:
CP000240_0497: domain 1 of 1, from 848 to 913: score 97.6, E = 1.8e-27
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTP++a++g++ lLle t+l++eq
CP000240_0 848 AKSSFLATMSHEIRTPMNAVLGMTGLLLE---------TPLNAEQ-- 883

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+++eti+ +++ ll Lind+Ld+s++eag
CP000240_0 884 ----------RDFVETIRISGDALLTLINDILDFSKLEAG 913

CP000240_1598: domain 1 of 1, from 815 to 880: score 96.0, E = 5.1e-27
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aksefla++sHE+RTP++aI+g+++lLl+ t l+++q
CP000240_1 815 AKSEFLATISHEIRTPINAILGMTSLLLD---------TSLDPQQ-- 850

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ ++ti+ +e ll+Lind+Ld+s+ie++
CP000240_1 851 ----------QDWVQTIRYGGEVLLNLINDILDFSKIESQ 880

CP000240_2354: domain 1 of 1, from 436 to 504: score 88.7, E = 6.1e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak +f++n+sHELRTPL +I+ ++e+L e+++ + s+e
CP000240_2 436 AKAQFISNISHELRTPLFSIKSFIETLYEYGE------QMSSAER-- 474

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+yle++ re++rl rL+nd+Ldlsr+e+g
CP000240_2 475 ----------LDYLEIANRETDRLTRLVNDVLDLSRLESG 504

CP000240_0962: domain 1 of 1, from 319 to 386: score 82.4, E = 3.8e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ks+flan sHELRTPL++I+g+++l l+++ +e ee+
CP000240_0 319 LKSQFLANTSHELRTPLNGIIGFIKLVLDGM-------AENREEE-- 356

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l+ ++r+a +ll+Lind+Ld+++ieag
CP000240_0 357 ----------LDFLQEAYRSALHLLALINDVLDIAKIEAG 386

CP000240_0027: domain 1 of 1, from 752 to 818: score 79.5, E = 2.5e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k++fl+++sHELRTP+t +r+++++L++ t ++e++
CP000240_0 752 LKDDFLSTVSHELRTPMTNVRMALQMLQM---------TRDNPEKQ- 788

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r y+ ++l+e +r +LindlLd+ r++ag
CP000240_0 789 ----------RHYFTIALKECNRQIELINDLLDMRRLGAG 818

CP000240_1727: domain 1 of 1, from 1025 to 1090: score 76.0, E = 2.4e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k++f++++sHELRTPL+++++++++L++ ++ +e+
CP000240_1 1025 LKDDFISTVSHELRTPLASMKMALKMLQM---------APTGEKR-- 1060

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl +++re +r +LindlLdl r+ ag
CP000240_1 1061 ----------AQYLAIAERECQREIELINDLLDLQRLKAG 1090

CP000240_2398: domain 1 of 1, from 598 to 663: score 75.5, E = 3.4e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k++fl+++sHELRTP+t +r++++lL++ + ++ +
CP000240_2 598 LKDDFLSTVSHELRTPITNMRMAIQLLKT---------ARAPQKR-- 633

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+++++e er +L+ndlLdl r+e+g
CP000240_2 634 ----------EQYLKILEQECEREAELVNDLLDLQRLEQG 663

CP000240_2404: domain 1 of 1, from 337 to 404: score 75.4, E = 3.5e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
akse++a HELRTPL++I+ +e L d++++ e r
CP000240_2 337 AKSELIAVTGHELRTPLSTIQVCLESLAS--------DPDMPLEMR- 374

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+l+t+l++a+rl++L++d+L+ls++e+g
CP000240_2 375 ----------QEMLNTALQDADRLRELVQDFLTLSKLESG 404

CP000240_0836: domain 1 of 1, from 192 to 256: score 69.1, E = 2.1e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++++++++HEL+TPLt+Ir++ae+L+ ++ q
CP000240_0 192 QRDRWASDVAHELKTPLTSIRLLAETLQS----------RVDAAQ-- 226

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +e++l+e+ rl++L++dlL+ls + g
CP000240_0 227 ----------AVWVERLLNETLRLSHLVQDLLELSALNLG 256

CP000240_1375: domain 1 of 1, from 197 to 263: score 67.6, E = 5.7e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +f+a++sHELR PL++I+++++++l+ d+ l++++
CP000240_1 197 QLKQFTADASHELRSPLASIQTAVQVALA--------DSQLDADT-- 233

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ + ++r rl rL++dlL l+r ++g
CP000240_1 234 ----------RQRWQMVERLCLRLGRLVDDLLFLARHDSG 263

CP000240_1221: domain 1 of 1, from 53 to 122: score 65.2, E = 2.8e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ fla++sHELRTPLt+I++ ++lL+ + + ++l+++q+
CP000240_1 53 IRDNFLAAVSHELRTPLTSISLSVHLLKLSY-----QVSPLTPKQI- 93

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+yle+++++ er +LindlLdl + +
CP000240_1 94 -----------QYLEVLEQACEREISLINDLLDLQNLSGN 122

CP000240_1597: domain 1 of 1, from 187 to 252: score 63.0, E = 1.1e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ fla++sHELRTPLt I++++elL + ++l+e+q
CP000240_1 187 LKDSFLASVSHELRTPLTKIKLALELLGR---------SPLDEKQ-- 222

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+y +++l+e + +Lin+lLdl +ea
CP000240_1 223 ----------RQYHRIALEECQAEIELINRLLDLQGLEAK 252

CP000240_2718: domain 1 of 1, from 651 to 716: score 61.7, E = 2.6e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+efl ++sHE+RTPLt +++++ L + ++l+e +
CP000240_2 651 LKDEFLHMVSHEMRTPLTNMKLAIGFLSK---------ANLTERE-- 686

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+y+++++ e++r l+LindlL+l +e+g
CP000240_2 687 ----------RRYFQILEMETNRELELINDLLELQALESG 716

CP000240_2646: domain 1 of 1, from 211 to 274: score 53.4, E = 6e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELR PL+a++ +a+++l ++ ++ r
CP000240_2 211 QLQRFTADASHELRAPLAALMSNAQMALL---------APEQAQPR- 247

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le++ + a+rl+ Li+ lL+l+r +
CP000240_2 248 -------------LEKVVSGARRLSVLIDTLLQLARQQGS 274

CP000240_2713: domain 1 of 1, from 51 to 126: score 49.2, E = 9.4e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkv.lagdtelseeqr
k++fl+++sHELRTPL+ +++++ lL l ++++g + +++ +
CP000240_2 51 LKDDFLSTVSHELRTPLSNMKMAIRLLSSVL--LpAQGAPRSPDPAK 95

lpeLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +yl+++++e er rL++dlL+l ++e
CP000240_2 96 ----------ISQYLKVLDNECEREIRLVEDLLELQQLEVL 126

CP000240_0940: domain 1 of 1, from 41 to 108: score 47.8, E = 2.4e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e+l ++ HELR+PL++ +g ++l l +l s+e+
CP000240_0 41 FQQELLVSIGHELRNPLSSQMGSLQLVLSDL--------CDSPEEE- 78

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
reyl+++++++erl +L+++ l+r + +
CP000240_0 79 ----------REYLQSAKEAVERLIKLLEEYTRLARHDLP 108

CP000240_1847: domain 1 of 1, from 147 to 216: score 44.0, E = 2.9e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k++ la+l H+LR PLta +++e+L+ ++++ l+
CP000240_1 147 FKDRVLAMLVHDLRSPLTATALAVETLQQ------GREGSLDKALE- 186

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++++ ++++++ ++++i d+L+ +r a
CP000240_1 187 ----------RQLFDHARQQLRKMDSMITDILESARGAAS 216

CP000240_0693: domain 1 of 1, from 138 to 205: score 34.5, E = 1.4e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f+a+l H+L+TPL a ++++ + d+ l +eqr
CP000240_0 138 RREAFTATLVHDLKTPLIAFGHLLSAFKQ--------DQQLEPEQR- 175

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r +l++il+e ++ l+L++ + + r+e g
CP000240_0 176 ----------RALLDRILQENQHNLSLVQKMVEAHRLERG 205

CP000240_1315: domain 1 of 1, from 260 to 306: score 32.8, E = 4.2e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ e+l++l HE+ TPL++Ir++++l+l+ +++l++
CP000240_1 260 SEAELLRALIHEIQTPLSTIRTLVSLILK--------RHDLPSRV-- 296

peLRledpeyreyletilre<-*
rey+e+i+re
CP000240_1 297 ----------REYVEKIDRE 306

CP000240_1314: domain 1 of 1, from 30 to 93: score 28.5, E = 7e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ l++l HE+R+PLta++++a+lL++ l++e+r
CP000240_1 30 LSAQQLSTLLHEMRNPLTALSTLAKLLQK----------RLPPEDR- 65

peLRledpeyreylet.ilreaerllrLindlLdlsrieag<-*
+ +i++e ++l++L+ ++ +r++
CP000240_1 66 ----------NHWIGLsIEQECKHLQELLAEF---ERLDGI 93


Histogram of all scores:
score obs exp (one = represents 9 sequences)
----- --- ---
-15 3 0|=
-14 28 0|====
-13 68 2|*=======
-12 144 65|=======*========
-11 288 339|================================ *
-10 442 629|================================================== *
-9 472 649|===================================================== *
-8 492 486|=====================================================*=
-7 336 306|=================================*====
-6 221 176|===================*=====
-5 141 96|==========*=====
-4 85 51|=====*====
-3 45 27|==*==
-2 28 14|=*==
-1 20 7|*==
0 14 3|*=
1 10 2|*=
2 0 1|*
3 2 0|=
4 1 0|=
5 0 0|
6 0 0|
> 7 22 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 307.2806
P(chi-square) = 0

Total sequences searched: 2862

Whole sequence top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: